Tbx1 is necessary for palatal elongation and elevation

scientific article published on 7 March 2010

Tbx1 is necessary for palatal elongation and elevation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.MOD.2010.03.001
P932PMC publication ID2871954
P698PubMed publication ID20214979
P5875ResearchGate publication ID41848222

P2093author name stringH Scott Baldwin
Christopher Brown
Amy Law
Steven Goudy
Gabriela Sanchez
P2860cites workAbnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)Q24675845
DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1Q28204282
Irf6 is a key determinant of the keratinocyte proliferation-differentiation switchQ28268504
Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathwaysQ28511687
Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defectsQ28512647
TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndromeQ28512803
Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancyQ28586089
Defects in limb, craniofacial, and thymic development in Jagged2 mutant miceQ28586431
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palateQ28587665
Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouseQ28587760
Gli3-deficient mice exhibit cleft palate associated with abnormal tongue developmentQ28587791
Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery developmentQ28589109
The many faces and factors of orofacial cleftsQ33724077
Palatal fusion - where do the midline cells go? A review on cleft palate, a major human birth defectQ34564875
Specification and patterning of neural crest cells during craniofacial development.Q36299299
Recent advances in craniofacial morphogenesisQ36471176
Molecular control of secondary palate developmentQ36581780
Palatal seam disintegration: to die or not to die? that is no longer the questionQ37137587
Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence.Q37239895
An extracellular matrix infrastructure provides support for murine secondary palatal shelf remodellingQ38484994
Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse.Q44132458
Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouseQ47194311
Tbx1 is expressed at multiple sites of epithelial-mesenchymal interaction during early development of the facial complex.Q52021572
The cellular and molecular etiology of the cleft secondary palate in Fgf10 mutant mice.Q52085311
Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.Q52200425
Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations.Q52568551
P433issue5-6
P304page(s)292-300
P577publication date2010-03-07
P1433published inMechanisms of DevelopmentQ6804657
P1476titleTbx1 is necessary for palatal elongation and elevation
P478volume127

Reverse relations

cites work (P2860)
Q64926091Cellular and molecular mechanisms of cleft palate development.
Q36891185Contribution of polymorphisms in genes associated with craniofacial development to the risk of nonsyndromic cleft lip and/or palate in the Brazilian population.
Q28255041Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients
Q41249705Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development
Q37845412Disintegration of the medial epithelial seam: is cell death important in palatogenesis?
Q34187192Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations via mechanisms distinct to those caused by loss of Tbx1
Q55306118Gene expression profiling in the developing secondary palate in the absence of Tbx1 function.
Q42316991Genetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis.
Q54372898Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
Q49834334Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans.
Q35878640Implications of TGFβ on Transcriptome and Cellular Biofunctions of Palatal Mesenchyme
Q57186379Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transit
Q40186459Mapping cellular processes in the mesenchyme during palatal development in the absence of Tbx1 reveals complex proliferation changes and perturbed cell packing and polarity.
Q37736023MicroRNAs in Palatogenesis and Cleft Palate
Q28081179Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit development
Q36247698Mutations in HYAL2, Encoding Hyaluronidase 2, Cause a Syndrome of Orofacial Clefting and Cor Triatriatum Sinister in Humans and Mice
Q35085547Neural crest-specific deletion of Ldb1 leads to cleft secondary palate with impaired palatal shelf elevation
Q38199181Roles of retinoic acid signaling in normal and abnormal development of the palate and tongue
Q35234113TBX1 protein interactions and microRNA-96-5p regulation controls cell proliferation during craniofacial and dental development: implications for 22q11.2 deletion syndrome
Q35040180Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development
Q39271331Tbx1 regulates oral epithelial adhesion and palatal development.
Q48613114The regulation of endogenous retinoic acid level through CYP26B1 is required for elevation of palatal shelves
Q28592403Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis
Q37341674Understanding the role of Tbx1 as a candidate gene for 22q11.2 deletion syndrome

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