Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis

scientific journal article

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YDBIO.2005.08.037
P3181OpenCitations bibliographic resource ID1187036
P698PubMed publication ID16169548
P5875ResearchGate publication ID7593314

P2093author name stringJie Shen
Raphael Kopan
Zhenyi Liu
Yonghua Pan
P2860cites workNotch signaling controls multiple steps of pancreatic differentiationQ24569636
The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidanceQ28141216
Murine notch homologs (N1-4) undergo presenilin-dependent proteolysisQ28214246
Functions of FGF signalling from the apical ectodermal ridge in limb developmentQ28216618
A re-examination of proximodistal patterning during vertebrate limb developmentQ28216626
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domainQ28273268
Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridgeQ28511730
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant miceQ28512351
Jagged2: a serrate-like gene expressed during rat embryogenesisQ28580835
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18Q28584951
Defects in limb, craniofacial, and thymic development in Jagged2 mutant miceQ28586431
PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutationsQ28587440
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1Q28589104
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegenerationQ28590719
gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesisQ28591384
Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathwayQ28592687
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6Q28593218
Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathwayQ28593284
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family membersQ33929533
Patterning the embryonic axis: FGF signaling and how vertebrate embryos measure time.Q34340515
Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.Q34415366
A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesisQ38360357
Fgf8 is required for outgrowth and patterning of the limbsQ38525644
Serrate2 is disrupted in the mouse limb-development mutant syndactylismQ39454683
Genetic mosaic analysis indicates that the bulb region of coat hair follicles contains a resident population of several active multipotent epithelial lineage progenitors.Q39590790
Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling.Q40398123
Dorsal-ventral signaling in limb developmentQ41678568
Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud developmentQ41734974
A role for hairy1 in regulating chick limb bud growthQ43814674
Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegansQ44246281
An O-fucose site in the ligand binding domain inhibits Notch activationQ44662116
Gamma-secretase: proteasome of the membrane?Q44918417
Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neuronsQ45200176
Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limbQ46444960
Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activationQ47070716
Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteinsQ47072858
Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nailQ47406430
Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutationQ47408089
Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation.Q48052345
Expression patterns of Notch1, Serrate1, Serrate2 and Delta1 in tissues of the developing chick limb.Q52182018
Notch1 is essential for postimplantation development in mice.Q52512097
Expression of Cre recombinase in the developing mouse limb bud driven by aPrxl enhancerQ64965676
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
Presenilin 1Q21496912
Notch 2Q21986192
Notch 1Q21986193
Presenilin 2Q21988969
P304page(s)472–482
P577publication date2005-10-15
P1433published inDevelopmental BiologyQ3025402
P1476titleNotch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis
P478volume286

Reverse relations

cites work (P2860)
Q33307527An obligatory role of mind bomb-1 in notch signaling of mammalian development
Q21136351Bare bones pattern formation: a core regulatory network in varying geometries reproduces major features of vertebrate limb development and evolution
Q98474258Cell death in the developing vertebrate limb: A Locally regulated mechanism contributing to musculoskeletal tissue morphogenesis and differentiation
Q57456317Deficiency of lrp4 in zebrafish and human LRP4 mutation induce aberrant activation of Jagged-Notch signaling in fin and limb development
Q36950245Early pancreatic islet fate and maturation is controlled through RBP-Jκ
Q31152378Elucidating the genetic basis of an oligogenic birth defect using whole genome sequence data in a non-model organism, Bubalus bubalis
Q40114200Formation of normal interdigital web spaces in the hand revisited: implications for the pathogenesis of syndactyly in humans and experimental animals
Q95820013Geminin is required for Hox gene regulation to pattern the developing limb
Q21145242Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
Q33589613Genetic control of programmed cell death during animal development
Q28261852Haploinsufficiency of the NOTCH1 Receptor as a Cause of Adams-Oliver Syndrome With Variable Cardiac Anomalies
Q37845411Interdigital cell death function and regulation: new insights on an old programmed cell death model
Q24311638Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signaling
Q36973782Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
Q35941365Moonlighting activity of presenilin in plants is independent of gamma-secretase and evolutionarily conserved
Q37325961Nas transgenic mouse line allows visualization of Notch pathway activity in vivo.
Q39042666Notch in memories: Points to remember
Q46789753Notch in memories: Points to remember.
Q37339719Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
Q27333237Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity
Q27334560Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1
Q35739711Pleiotropic patterning response to activation of Shh signaling in the limb apical ectodermal ridge
Q37362813Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window
Q36820308The development of synovial joints.
Q38116930The molecular basis of human congenital limb malformations

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