scholarly article | Q13442814 |
P819 | ADS bibcode | 2013PLoSO...865190E |
P356 | DOI | 10.1371/JOURNAL.PONE.0065190 |
P932 | PMC publication ID | 3677893 |
P698 | PubMed publication ID | 23762313 |
P5875 | ResearchGate publication ID | 237200599 |
P50 | author | Magbubah Essack | Q58882445 |
Aleksandar Radovanovic | Q43371015 | ||
Vladimir B. Bajic | Q30347500 | ||
P2860 | cites work | Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients. | Q54585312 |
Attenuation of pulmonary hypertension secondary to left ventricular dysfunction in the rat by Rho-kinase inhibitor fasudil. | Q54655545 | ||
Indomethacin and Alzheimer's disease | Q57372930 | ||
Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease | Q58416036 | ||
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia | Q72704827 | ||
Levels of endothelial, neutrophil and platelet-specific factors in sickle cell anemia patients during hydroxyurea therapy | Q78208970 | ||
Leukocyte numbers correlate with plasma levels of granulocyte-macrophage colony-stimulating factor in sickle cell disease | Q79496860 | ||
Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis | Q83540454 | ||
Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line | Q39639963 | ||
Hydroxycarbamide stimulates the production of proinflammatory cytokines by endothelial cells: relevance to sickle cell disease | Q39729979 | ||
Gene expression profiles of erythroid precursors characterise several mechanisms of the action of hydroxycarbamide in sickle cell anaemia | Q40199173 | ||
Globin gene silencing in primary erythroid cultures. An inhibitory role for interleukin-6. | Q41094592 | ||
Improved survival in homozygous sickle cell disease: lessons from a cohort study | Q42061138 | ||
Therapy with hydroxyurea is associated with reduced adhesion molecule gene and protein expression in sickle red cells with a concomitant reduction in adhesive properties. | Q42508588 | ||
Cucurbitacin D induces fetal hemoglobin synthesis in K562 cells and human hematopoietic progenitors through activation of p38 pathway and stabilization of the γ-globin mRNA | Q42868264 | ||
Fasudil protects hippocampal neurons against hypoxia‐reoxygenation injury by suppressing microglial inflammatory responses in mice | Q42873128 | ||
Rho-kinase signalling regulates CXC chemokine formation and leukocyte recruitment in colonic ischemia-reperfusion | Q42996719 | ||
Dragon exploratory system on hepatitis C virus (DESHCV). | Q43032574 | ||
Amelioration of endothelial damage/dysfunction is a possible mechanism for the neuroprotective effects of Rho-kinase inhibitors against ischemic brain damage | Q43282369 | ||
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin | Q44189616 | ||
Increased soluble guanylate cyclase activity in the red blood cells of sickle cell patients | Q44776810 | ||
Circulating endothelin-3 levels in patients with sickle cell disease during hydroxyurea treatment. | Q44799590 | ||
Altered levels of cytokines and inflammatory mediators in plasma and leukocytes of sickle cell anemia patients and effects of hydroxyurea therapy | Q44929555 | ||
Involvement of Rho-kinase in cold ischemia-reperfusion injury after liver transplantation in rats | Q45022046 | ||
Decreased plasma endothelin-1 levels in children with sickle cell disease treated with hydroxyurea. | Q45304426 | ||
Campaign to control genetic blood diseases in Bahrain | Q46378992 | ||
Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells | Q46530038 | ||
Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition | Q46637737 | ||
DESTAF: a database of text-mined associations for reproductive toxins potentially affecting human fertility | Q46743543 | ||
MedlineRanker: flexible ranking of biomedical literature | Q22242846 | ||
Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase | Q24554376 | ||
Entrez Gene: gene-centered information at NCBI | Q24670011 | ||
The KEGG databases at GenomeNet | Q27933576 | ||
Reactome: a knowledge base of biologic pathways and processes | Q28757721 | ||
The Universal Protein Resource (UniProt) 2009 | Q29619148 | ||
DDESC: Dragon database for exploration of sodium channels in human | Q30855778 | ||
State of the nation in data integration for bioinformatics | Q31150346 | ||
Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line | Q33253539 | ||
Naamidines H and I, cytotoxic imidazole alkaloids from the Indonesian marine sponge Leucetta chagosensis | Q33297792 | ||
DDEC: Dragon database of genes implicated in esophageal cancer | Q33478723 | ||
Placenta growth factor-induced early growth response 1 (Egr-1) regulates hypoxia-inducible factor-1alpha (HIF-1alpha) in endothelial cells | Q33966992 | ||
Sickle-cell disease | Q34153339 | ||
DDPC: Dragon Database of Genes associated with Prostate Cancer | Q34456593 | ||
Integrating biological databases | Q35120173 | ||
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice | Q35140955 | ||
Hydroxyurea for sickle cell anemia: what have we learned and what questions still remain? | Q35234959 | ||
Recent advances in globin gene transfer for the treatment of beta-thalassemia and sickle cell anemia | Q36433492 | ||
Text-based discovery in biomedicine: the architecture of the DAD-system | Q36460944 | ||
Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia | Q36591800 | ||
Induction of fetal hemoglobin in the treatment of sickle cell disease | Q36662091 | ||
PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites | Q36749427 | ||
Anni 2.0: a multipurpose text-mining tool for the life sciences | Q36787149 | ||
DP-155, a lecithin derivative of indomethacin, is a novel nonsteroidal antiinflammatory drug for analgesia and Alzheimer's disease therapy. | Q36879568 | ||
Sphingosine-1-phosphate and interleukin-1 independently regulate plasminogen activator inhibitor-1 and urokinase-type plasminogen activator receptor expression in glioblastoma cells: implications for invasiveness | Q36982983 | ||
Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage | Q37023057 | ||
SciMiner: web-based literature mining tool for target identification and functional enrichment analysis | Q37126103 | ||
Database for exploration of functional context of genes implicated in ovarian cancer | Q37202563 | ||
Knowledge discovery by automated identification and ranking of implicit relationships | Q38423824 | ||
HCVpro: hepatitis C virus protein interaction database | Q38484332 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | sickle-cell disease | Q185034 |
P304 | page(s) | e65190 | |
P577 | publication date | 2013-01-01 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Information exploration system for sickle cell disease and repurposing of hydroxyfasudil | |
P478 | volume | 8 |
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Q41075666 | DES-TOMATO: A Knowledge Exploration System Focused On Tomato Species. |
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Q28082443 | Recent Advances and Emerging Applications in Text and Data Mining for Biomedical Discovery |
Q39152826 | What are the most promising emerging therapies for sickle cell disease? |