| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Eran Dvir | |
| Arik Dahan | |||
| Amnon Hoffman | |||
| Jonathan E Friedman | |||
| Danielle Simmons | |||
| Israel Shapiro | |||
| Revital Duvdevani | |||
| Anat Elman | |||
| P2860 | cites work | Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice | Q22242267 |
| NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo | Q24679444 | ||
| Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain | Q28137790 | ||
| Direct cytotoxicity of non-steroidal anti-inflammatory drugs in acidic media: model study on human erythrocytes with DIDS-inhibited anion exchanger | Q28194803 | ||
| Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation | Q28205815 | ||
| Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways | Q28374821 | ||
| Phospholipase A2 enzymes | Q28609770 | ||
| Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease | Q29614374 | ||
| Drug-phospholipid conjugates as potential prodrugs: synthesis, characterization, and degradation by pancreatic phospholipase A(2). | Q31613227 | ||
| Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. | Q31840691 | ||
| Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease | Q32028060 | ||
| Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity | Q33187378 | ||
| Inflammation of the brain in Alzheimer's disease: implications for therapy. | Q33594683 | ||
| Alzheimer's disease and inflammation: a review of cellular and therapeutic mechanisms | Q33851318 | ||
| Rationale and applications of lipids as prodrug carriers | Q34061168 | ||
| Epidemiology and pharmacoeconomic implications of non-steroidal anti-inflammatory drug-associated gastrointestinal toxicity | Q34200679 | ||
| Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes | Q34452028 | ||
| Indomethacin for the treatment of Alzheimer's disease patients | Q34699322 | ||
| Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease | Q35103526 | ||
| COX-3 the enzyme and the concept: steps towards highly specialized pathways and precision therapeutics? | Q35568844 | ||
| Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology | Q35747757 | ||
| Intraneuronal Abeta42 accumulation in human brain. | Q35793325 | ||
| Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action | Q35918744 | ||
| Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation | Q35952432 | ||
| NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies | Q36477257 | ||
| The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases | Q36552432 | ||
| Improvement of the gastric tolerance of non-steroidal anti-inflammatory drugs by polyene phosphatidylcholine (Phospholipon 100). | Q38590136 | ||
| Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin. | Q40455953 | ||
| A comparative study of the antipyretic effects of indomethacin and dipyrone in rats. | Q40588134 | ||
| COX-1, COX-2, and COX-3 and the future treatment of chronic inflammatory disease | Q40775836 | ||
| The antipyretic effect of indomethacin | Q40896058 | ||
| Inflammation and Alzheimer's disease pathogenesis | Q41189072 | ||
| Renal and gastric lesions after phenylbutazone and indomethacin in the rat. | Q42233408 | ||
| Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. | Q43638880 | ||
| NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. | Q43726776 | ||
| A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity | Q43793656 | ||
| Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists | Q44044362 | ||
| In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile | Q44345724 | ||
| Integrins regulate NMDA receptor-mediated synaptic currents. | Q44436425 | ||
| COX-2 inhibitors--lessons in drug safety | Q45267551 | ||
| Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice | Q48242315 | ||
| Are there fundamental differences in the peripheral mechanisms of visceral and somatic pain? | Q48252407 | ||
| Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling | Q48463246 | ||
| A novel phospholipid derivative of indomethacin, DP-155 [mixture of 1-steroyl and 1-palmitoyl-2-{6-[1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetamido]hexanoyl}-sn-glycero-3-phosophatidyl [corrected] choline], shows superior safety and simil | Q48504674 | ||
| Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice | Q48846848 | ||
| Local cerebral circulatory and metabolic effects of indomethacin | Q48903850 | ||
| Central effect of the non-steroid anti-inflammatory agents, indomethacin, ibuprofen, and diclofenac, determined in C fibre-evoked activity in single neurones of the rat thalamus | Q49027269 | ||
| Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain | Q49122730 | ||
| Clinical trial of indomethacin in Alzheimer's disease. | Q53318286 | ||
| Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease | Q57782086 | ||
| Prevention of cytokine-induced changes in leukocyte adhesion receptors by nonsteroidal antiinflammatory drugs from the oxicam family | Q58064524 | ||
| Effect of Anti-inflammatory Medications on Neuropathological Findings in Alzheimer Disease | Q59544668 | ||
| The differentiation of NSAIDs and prostaglandin action using a mechanical visceral pain model in the rat | Q69730164 | ||
| Role of the renal prostaglandins in furosemide-induced diuresis | Q70944265 | ||
| Differential effect of three cyclooxygenase inhibitors on human cerebral blood flow velocity and carbon dioxide reactivity | Q72157142 | ||
| Central mechanism of indomethacin analgesia | Q72408753 | ||
| Interaction of indomethacin and naproxen with gastric surface-active phospholipids: a possible mechanism for the gastric toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs) | Q77799753 | ||
| A novel mechanism for oral controlled release of drugs by continuous degradation of a phospholipid prodrug along the intestine: in-vivo and in-vitro evaluation of an indomethacin-lecithin conjugate | Q80028177 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Alzheimer's disease | Q11081 |
| P304 | page(s) | 260-277 | |
| P577 | publication date | 2007-01-01 | |
| P1433 | published in | CNS Neuroscience & Therapeutics | Q5013184 |
| P1476 | title | DP-155, a lecithin derivative of indomethacin, is a novel nonsteroidal antiinflammatory drug for analgesia and Alzheimer's disease therapy | |
| P478 | volume | 13 |
| Q47442677 | Computational modeling and in-vitro/in-silico correlation of phospholipid-based prodrugs for targeted drug delivery in inflammatory bowel disease. |
| Q41075666 | DES-TOMATO: A Knowledge Exploration System Focused On Tomato Species. |
| Q28533770 | Information exploration system for sickle cell disease and repurposing of hydroxyfasudil |
| Q51042522 | Modern prodrug design for targeted oral drug delivery. |
| Q91796750 | Molecular Modeling-Guided Design of Phospholipid-Based Prodrugs |
| Q93159935 | Phospholipid-Based Prodrugs for Colon-Targeted Drug Delivery: Experimental Study and In-Silico Simulations |
| Q37735764 | Phospholipids and lipid-based formulations in oral drug delivery |
| Q37193593 | Progress in drug delivery to the central nervous system by the prodrug approach. |
| Q58575563 | Prospects and Challenges of Phospholipid-Based Prodrugs |
| Q38019048 | Targeted prodrugs in oral drug delivery: the modern molecular biopharmaceutical approach. |
| Q37657525 | Various drug delivery approaches to the central nervous system |
Search more.