| scholarly article | Q13442814 |
| P2093 | author name string | Bayer TA | |
| Beyreuther K | |||
| Czech C | |||
| Multhaup G | |||
| Wirths O | |||
| Blanchard V | |||
| Pradier L | |||
| Tremp G | |||
| Moussaoui S | |||
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| P433 | issue | 1-2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 116-120 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | Neuroscience Letters | Q7002625 |
| P1476 | title | Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice | |
| P478 | volume | 306 |
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| Q35084882 | Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice |
| Q37102001 | Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology |
| Q33955075 | Alpha7 nicotinic acetylcholine receptor: a link between inflammation and neurodegeneration. |
| Q30499574 | Alzheimer disease models and human neuropathology: similarities and differences |
| Q48430413 | Alzheimer's disease and Alzheimer's dementia: distinct but overlapping entities |
| Q36713885 | Alzheimer's disease protein Abeta1-42 does not disrupt isolated synaptic vesicles |
| Q35899503 | Alzheimer's disease: a clinical practice-oriented review |
| Q38006665 | Amyloid and Alzheimer's disease: inside and out. |
| Q38242621 | Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease |
| Q33914305 | Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. |
| Q33515877 | Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide |
| Q47339779 | Amyloid β oligomers (AβOs) in Alzheimer's disease |
| Q30476347 | Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline |
| Q26739839 | Amyloidosis in Retinal Neurodegenerative Diseases |
| Q33927819 | An overview of APP processing enzymes and products |
| Q28306851 | Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation |
| Q44410484 | Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains |
| Q64258466 | Autophagy Activator Drugs: A New Opportunity in Neuroprotection from Misfolded Protein Toxicity |
| Q41506935 | Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A. |
| Q37993451 | Aβ toxicity in Alzheimer's disease |
| Q33918218 | Back to the future with phenotypic screening |
| Q46768341 | Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses |
| Q93076147 | Blast-Mediated Traumatic Brain Injury Exacerbates Retinal Damage and Amyloidosis in the APPswePSENd19e Mouse Model of Alzheimer's Disease |
| Q55514851 | Brain Energy and Oxygen Metabolism: Emerging Role in Normal Function and Disease. |
| Q22252362 | Brain cholinesterases: II. The molecular and cellular basis of Alzheimer's disease |
| Q26851244 | Caenorhabditis elegans as a model organism to study APP function |
| Q30633722 | Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology |
| Q34460818 | Ceramide and Related-Sphingolipid Levels Are Not Altered in Disease-Associated Brain Regions of APP and APP/PS1 Mouse Models of Alzheimer's Disease: Relationship with the Lack of Neurodegeneration? |
| Q41907734 | Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer's disease |
| Q93061586 | Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice |
| Q30495675 | Co-occurrence of Alzheimer's disease ß-amyloid and τ pathologies at synapses. |
| Q44214690 | Consistent immunohistochemical detection of intracellular beta-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex |
| Q61800926 | Contribution of syndecans to cellular internalization and fibrillation of amyloid-β(1-42) |
| Q36342011 | Critical role of intraneuronal Aβ in Alzheimer's disease: technical challenges in studying intracellular Aβ. |
| Q46046558 | Curcumin Ameliorates Neuroinflammation, Neurodegeneration, and Memory Deficits in p25 Transgenic Mouse Model that Bears Hallmarks of Alzheimer's Disease. |
| Q39672283 | DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration |
| Q36879568 | DP-155, a lecithin derivative of indomethacin, is a novel nonsteroidal antiinflammatory drug for analgesia and Alzheimer's disease therapy. |
| Q48348329 | Detection of vascular alterations by in vivo magnetic resonance angiography and histology in APP/PS1 mouse model of Alzheimer's disease. |
| Q34063838 | Development of a novel cellular model of Alzheimer's disease utilizing neurosphere cultures derived from B6C3-Tg(APPswe,PSEN1dE9)85Dbo/J embryonic mouse brain |
| Q34043269 | Distinct temporal and anatomical distributions of amyloid-β and tau abnormalities following controlled cortical impact in transgenic mice |
| Q48102481 | Down syndrome, beta-amyloid and neuroimaging |
| Q34276376 | Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model |
| Q48112174 | Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer's disease |
| Q38502400 | Effect of amyloids on the vesicular machinery: implications for somatic neurotransmission |
| Q36964574 | Effects of Alzheimer's amyloid-beta and tau protein on mitochondrial function -- role of glucose metabolism and insulin signalling |
| Q48505432 | Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture |
| Q40564428 | Effects of neprilysin chimeric proteins targeted to subcellular compartments on amyloid beta peptide clearance in primary neurons |
| Q30497246 | Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice. |
| Q40893495 | Endocytic pathways mediating oligomeric Abeta42 neurotoxicity. |
| Q36870079 | Environmental and dietary risk factors in Alzheimer's disease |
| Q48228188 | Evidence linking neuronal cell death to autoimmunity in Alzheimer's disease |
| Q48562250 | Expression of the Alzheimer's Disease Mutations AβPP695sw and PSEN1M146I in Double-Transgenic Göttingen Minipigs |
| Q48382178 | Extracellular amyloid formation and associated pathology in neural grafts |
| Q35207688 | Fiber Tracts Anomalies in APPxPS1 Transgenic Mice Modeling Alzheimer's Disease |
| Q46706790 | Gradual alteration of mitochondrial structure and function by beta-amyloids: importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release |
| Q35474378 | High-resolution 3D reconstruction reveals intra-synaptic amyloid fibrils. |
| Q24672501 | Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease |
| Q35569964 | How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario |
| Q36983713 | Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice |
| Q59543826 | Impact of Aging: Sporadic, and Genetic Risk Factors on Vulnerability to Apoptosis in Alzheimer's Disease |
| Q35578470 | Impaired β-amyloid secretion in Alzheimer's disease pathogenesis |
| Q39431937 | Implications of peptide assemblies in amyloid diseases |
| Q35700403 | Increased apoptotic cell death in sporadic and genetic Alzheimer's disease |
| Q36884880 | Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease. |
| Q37257172 | Independent effects of intra- and extracellular Abeta on learning-related gene expression |
| Q34035607 | Interaction of intracellular beta amyloid peptide with chaperone proteins |
| Q40139351 | Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. |
| Q34995075 | Intracellular A-beta amyloid, a sign for worse things to come? |
| Q36795149 | Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome |
| Q37765478 | Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease |
| Q42004000 | Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons. |
| Q29615626 | Intracellular amyloid-beta in Alzheimer's disease |
| Q42386276 | Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system. |
| Q57777652 | Intraneuronal -Amyloid Expression Downregulates the Akt Survival Pathway and Blunts the Stress Response |
| Q35683326 | Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration |
| Q35747757 | Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology |
| Q48696171 | Intraneuronal Aβ accumulation, amyloid plaques, and synapse pathology in Alzheimer's disease. |
| Q35968298 | Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. |
| Q33674631 | Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease |
| Q35246412 | Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease |
| Q39066009 | Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain |
| Q30489966 | Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model |
| Q34019193 | Is Alzheimer's disease a systemic disease? |
| Q34020079 | Late-onset Alzheimer's disease, heating up and foxed by several proteins: pathomolecular effects of the aging process. |
| Q37630543 | MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE. |
| Q30478167 | Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model |
| Q41487372 | Mechanisms of amyloid-Beta Peptide uptake by neurons: the role of lipid rafts and lipid raft-associated proteins |
| Q35959633 | Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology |
| Q34922777 | Mitochondria, Amyloid β, and Alzheimer's Disease |
| Q33288260 | Mitochondrial oxidative stress causes hyperphosphorylation of tau. |
| Q36938297 | Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer's disease |
| Q41195874 | Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice |
| Q28510031 | Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implication |
| Q42278922 | N-truncated Aβ4-x peptides in sporadic Alzheimer's disease cases and transgenic Alzheimer mouse models |
| Q51029900 | Neurofibrillary Tangles of Aβx-40 in Alzheimer's Disease Brains. |
| Q38297925 | Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer's disease. |
| Q40650184 | Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway |
| Q38118901 | Neurotoxic saboteurs: straws that break the hippo's (hippocampus) back drive cognitive impairment and Alzheimer's Disease |
| Q44384541 | No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment |
| Q47798328 | Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. |
| Q39627415 | Overexpression of neprilysin reduces alzheimer amyloid-beta42 (Abeta42)-induced neuron loss and intraneuronal Abeta42 deposits but causes a reduction in cAMP-responsive element-binding protein-mediated transcription, age-dependent axon pathology, an |
| Q42729244 | Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models |
| Q38959054 | Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity. |
| Q38872162 | Physical Exercise and Brain Mitochondrial Fitness: The Possible Role Against Alzheimer's Disease. |
| Q64057694 | Preliminary Study on Clusterin Protein (sCLU) Expression in PC-12 Cells Overexpressing Wild-Type and Mutated (Swedish) genes Affected by Non-Steroid Isoprenoids and Water-Soluble Cholesterol |
| Q48529619 | Presenilins are not required for A beta 42 production in the early secretory pathway |
| Q36942363 | RAGE is a key cellular target for Abeta-induced perturbation in Alzheimer's disease |
| Q41442163 | Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons |
| Q42425842 | Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. |
| Q44641925 | Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models |
| Q34105167 | Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice |
| Q37294108 | Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model |
| Q48553698 | Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody |
| Q36324215 | Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons |
| Q41160304 | Staging of cognitive deficits and neuropathological and ultrastructural changes in streptozotocin-induced rat model of Alzheimer's disease |
| Q35103335 | Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice |
| Q34028039 | Synapses, synaptic activity and intraneuronal abeta in Alzheimer's disease |
| Q30491040 | Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations |
| Q37855544 | The Relationship between Parkin and Protein Aggregation in Neurodegenerative Diseases |
| Q36241698 | The Role of Autophagy in the Correlation Between Neuron Damage and Cognitive Impairment in Rat Chronic Cerebral Hypoperfusion |
| Q34493230 | The absence of myelin basic protein promotes neuroinflammation and reduces amyloid β-protein accumulation in Tg-5xFAD mice |
| Q41635913 | The effects of endogenous non-peptide molecule isatin and hydrogen peroxide on proteomic profiling of rat brain amyloid-β binding proteins: relevance to Alzheimer's disease? |
| Q33936364 | The novel amyloid-beta peptide aptamer inhibits intracellular amyloid-beta peptide toxicity |
| Q36063543 | The role of caspase cleavage of tau in Alzheimer disease neuropathology |
| Q38214602 | The role of intracellular zinc release in aging, oxidative stress, and Alzheimer's disease |
| Q33715954 | The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice |
| Q79322897 | Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice |
| Q37266151 | Tissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views. |
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| Q53269757 | [The role of copper in the pathophysiology of Alzheimer's disease]. |
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