Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1

scientific article (publication date: 2013)

Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1 is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...872424Z
P356DOI10.1371/JOURNAL.PONE.0072424
P932PMC publication ID3748068
P698PubMed publication ID23977297
P5875ResearchGate publication ID256102682

P50authorJunyan LuQ51550184
Ruihan ZhangQ57563948
P2093author name stringXin Li
Lin Li
Cheng Luo
Xiangqian Kong
Yujun George Zheng
Zhongjie Liang
Kongkai Zhu
Sisheng Ouyang
P2860cites workGeometry optimization with QM/MM, ONIOM, and other combined methods. I. Microiterations and constraints.Q51639495
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Substrate-Induced Control of Product Formation by Protein Arginine Methyltransferase 1Q56923550
Understanding product specificity of protein lysine methyltransferases from QM/MM molecular dynamics and free energy simulations: the effects of mutation on SET7/9 beyond the Tyr/Phe switchQ83227936
PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory functionQ24313443
Regulation of estrogen rapid signaling through arginine methylation by PRMT1Q24317316
Crystal structure of the conserved core of protein arginine methyltransferase PRMT3Q24631369
H++: a server for estimating pKas and adding missing hydrogens to macromoleculesQ24813167
Comparison of simple potential functions for simulating liquid waterQ26778447
Modeling a new water channel that allows SET9 to dimethylate p53Q27341883
The structure and oligomerization of the yeast arginine methyltransferase, Hmt1Q27628760
Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of Its Binding to Substrate PeptidesQ27641186
Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMTQ27641462
Insights into histone code syntax from structural and biochemical studies of CARM1 methyltransferaseQ27648374
Functional insights from structures of coactivator-associated arginine methyltransferase 1 domainsQ27648377
Structural Biology of Human H3K9 MethyltransferasesQ27659033
Chemogenetic analysis of human protein methyltransferasesQ27667805
Investigation of the Molecular Origins of Protein-arginine Methyltransferase I (PRMT1) Product Specificity Reveals a Role for Two Conserved Methionine ResiduesQ27670511
Crystal Structure of the Plant Epigenetic Protein Arginine Methyltransferase 10Q27674910
Structural insights into protein arginine symmetric dimethylation by PRMT5Q27675998
VMD: visual molecular dynamicsQ27860554
The Amber biomolecular simulation programsQ27860745
Comparison of multiple Amber force fields and development of improved protein backbone parametersQ27861040
Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational studyQ28477309
A combined quantum mechanical and molecular mechanical potential for molecular dynamics simulationsQ29305558
Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanesQ29397708
Development and testing of a general amber force fieldQ29547642
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptorQ29614530
Protein arginine methylation in mammals: who, what, and whyQ29617309
SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase foldQ29618153
Measuring conformational dynamics of biomolecules by single molecule fluorescence spectroscopyQ34019499
Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylationQ34113450
Investigation of the acetylation mechanism by GCN5 histone acetyltransferaseQ34264881
Protein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexesQ34752160
A transient kinetic analysis of PRMT1 catalysisQ35156782
Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferasesQ36557929
Protein arginine methyltransferases (PRMTs) as therapeutic targetsQ38012526
Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1.Q38464556
Target-based approach to inhibitors of histone arginine methyltransferasesQ40146057
Kinetic mechanism of protein arginine methyltransferase 1.Q41975588
Protein arginine methyltransferase 1: positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysisQ42106743
Investigation of the Catalytic Mechanism of Sir2 Enzyme with QM/MM Approach: SN1 vs SN2?Q42931298
A quantum mechanics/molecular mechanics study of the catalytic mechanism and product specificity of viral histone lysine methyltransferase.Q45988311
Histone lysine methyltransferase SET7/9: formation of a water channel precedes each methyl transferQ46263113
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)e72424
P577publication date2013-01-01
P1433published inPLOS OneQ564954
P1476titleTheoretical insights into catalytic mechanism of protein arginine methyltransferase 1
P478volume8

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cites work (P2860)
Q93239156A Family Divided: Distinct Structural and Mechanistic Features of the SpoU-TrmD (SPOUT) Methyltransferase Superfamily
Q37691602A remodeled protein arginine methyltransferase 1 (PRMT1) generates symmetric dimethylarginine
Q35884628BTG1 potentiates apoptosis and suppresses proliferation in renal cell carcinoma by interacting with PRMT1
Q35722457Chemical biology of protein arginine modifications in epigenetic regulation
Q85277949Computational Study of Symmetric Methylation on Histone Arginine Catalyzed by Protein Arginine Methyltransferase PRMT5 through QM/MM MD and Free Energy Simulations

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