scholarly article | Q13442814 |
P50 | author | Sabine Rüsch-Gerdes | Q30002009 |
Stefan Niemann | Q30011787 | ||
Thomas A Kohl | Q53678284 | ||
Lanfranco Fattorini | Q56424438 | ||
Helen Cox | Q38641538 | ||
Marco R. Oggioni | Q42137324 | ||
P2093 | author name string | Elvira Richter | |
Andreas Roetzer | |||
Francis Varaine | |||
Leona Truebe | |||
Matthias Merker | |||
P2860 | cites work | Mechanism of thioamide drug action against tuberculosis and leprosy | Q24676495 |
The Beijing genotype and drug resistant tuberculosis in the Aral Sea region of Central Asia | Q24814887 | ||
Molecular genetic analysis of nucleotide polymorphisms associated with ethambutol resistance in human isolates of Mycobacterium tuberculosis | Q28343859 | ||
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis | Q28344564 | ||
Genomic diversity among drug sensitive and multidrug resistant isolates of Mycobacterium tuberculosis with identical DNA fingerprints | Q28476294 | ||
Treatment of tuberculosis in a region with high drug resistance: outcomes, drug resistance amplification and re-infection | Q28476640 | ||
Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients | Q28482730 | ||
Whole genome sequencing versus traditional genotyping for investigation of a Mycobacterium tuberculosis outbreak: a longitudinal molecular epidemiological study | Q28709007 | ||
The magic bullets and tuberculosis drug targets. | Q30350532 | ||
Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis | Q30419570 | ||
Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study | Q31107101 | ||
VarDetect: a nucleotide sequence variation exploratory tool | Q33393974 | ||
Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates | Q33970864 | ||
Evolution of high mutation rates in experimental populations of E. coli | Q34429727 | ||
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. | Q34508854 | ||
Drug-susceptible Mycobacterium tuberculosis Beijing genotype does not develop mutation-conferred resistance to rifampin at an elevated rate | Q34975227 | ||
Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection | Q35006626 | ||
Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis | Q35627816 | ||
Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes. | Q35635595 | ||
Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background. | Q53442441 | ||
Role of mutator alleles in adaptive evolution. | Q54564129 | ||
Exclusive mutations related to isoniazid and ethionamide resistance among Mycobacterium tuberculosis isolates from Korea | Q57216216 | ||
Characteristics of drug-resistant tuberculosis in Abkhazia (Georgia), a high-prevalence area in Eastern Europe | Q60441794 | ||
Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB. | Q35844623 | ||
Microevolution of extensively drug-resistant tuberculosis in Russia | Q35864738 | ||
Mycobacterium tuberculosis population structure determines the outcome of genetics-based second-line drug resistance testing | Q35941443 | ||
Mycobacterium tuberculosis thymidylate synthase gene thyX is essential and potentially bifunctional, while thyA deletion confers resistance to p-aminosalicylic acid | Q35960308 | ||
Detection of first- and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing | Q36022970 | ||
Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients | Q36368678 | ||
Double infection with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis | Q37065017 | ||
Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis | Q37184072 | ||
Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis | Q37190809 | ||
Infectiousness, reproductive fitness and evolution of drug-resistant Mycobacterium tuberculosis. | Q37634147 | ||
Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs | Q37874018 | ||
Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis | Q39743333 | ||
Mechanisms of drug resistance in Mycobacterium tuberculosis | Q43253948 | ||
The tempo and mode of molecular evolution of Mycobacterium tuberculosis at patient-to-patient scale | Q43260011 | ||
Molecular epidemiology and drug resistance of widespread genotypes of Mycobacterium tuberculosis in northwestern Russia. | Q43269048 | ||
Exact and complete short-read alignment to microbial genomes using Graphics Processing Unit programming | Q43918351 | ||
Emergence of extensive drug resistance during treatment for multidrug-resistant tuberculosis | Q43949976 | ||
Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis | Q44198145 | ||
In-vitro activity of rifabutin against rifampicin-resistant Mycobacterium tuberculosis isolates with known rpoB mutations | Q44950221 | ||
Comparison of gyrA gene mutations between laboratory-selected ofloxacin-resistant Mycobacterium tuberculosis strains and clinical isolates | Q46829493 | ||
Genetic polymorphism in Mycobacterium tuberculosis isolates from patients with chronic multidrug-resistant tuberculosis | Q47348924 | ||
Tuberculosis ethambutol resistance: concordance between phenotypic and genotypic test results | Q47862617 | ||
The Beijing genotype is a major cause of drug-resistant tuberculosis in Kazakhstan. | Q47877435 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Mycobacterium tuberculosis | Q130971 |
Beijing | Q956 | ||
multiple drug resistance | Q643839 | ||
whole genome sequencing | Q2068526 | ||
P304 | page(s) | e82551 | |
P577 | publication date | 2013-01-01 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients | |
P478 | volume | 8 |
Q59200572 | Advances in Tuberculosis Diagnostics |
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Q40463792 | Early diagnosis and effective treatment regimens are the keys to tackle antimicrobial resistance in tuberculosis (TB): A report from Euroscicon's international TB Summit 2016. |
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Q103001977 | Integron gene cassettes harboring novel variants of D-alanine-D-alanine ligase confer high-level resistance to D-cycloserine |
Q26752616 | Interpreting whole genome sequencing for investigating tuberculosis transmission: a systematic review |
Q40683305 | Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance |
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Q28389409 | Methodological and Clinical Aspects of the Molecular Epidemiology of Mycobacterium tuberculosis and Other Mycobacteria |
Q47173840 | Multi-clonal evolution of multi-drug-resistant/extensively drug-resistant Mycobacterium tuberculosis in a high-prevalence setting of Papua New Guinea for over three decades |
Q61814968 | Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery |
Q49289731 | Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts |
Q38616709 | PathoBacTyper: A Web Server for Pathogenic Bacteria Identification and Molecular Genotyping |
Q30927278 | PhyResSE: a Web Tool Delineating Mycobacterium tuberculosis Antibiotic Resistance and Lineage from Whole-Genome Sequencing Data |
Q38966881 | Potential for adaptation overrides cost of resistance. |
Q37132034 | Rapid Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates Directly from Clinical Samples by Use of Amplicon Sequencing: a Proof-of-Concept Study |
Q41991754 | Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance |
Q90286638 | Sources of multi-drug resistance in patients with previous isoniazid resistant tuberculosis identified using whole genome sequencing: A longitudinal cohort study |
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Q38210265 | Totally drug-resistant tuberculosis and adjunct therapies. |
Q37247747 | Tracing Mycobacterium tuberculosis transmission by whole genome sequencing in a high incidence setting: a retrospective population-based study in East Greenland |
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