Role of mutator alleles in adaptive evolution.

scientific article

Role of mutator alleles in adaptive evolution. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1031812288
P356DOI10.1038/42696
P698PubMed publication ID9192893
P5875ResearchGate publication ID14026143

P50authorMiroslav RadmanQ2749478
P2093author name stringTaddei F
Godelle B
Gouyon PH
Maynard-Smith J
Toupance B
P2860cites workLong-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 GenerationsQ22066139
Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populationsQ28245607
A constant rate of spontaneous mutation in DNA-based microbesQ28271032
How clonal are bacteria?Q29618572
The mutation rate and cancerQ34410886
Evolution of high mutation rates in experimental populations of E. coliQ34429727
Proliferation of mutators in A cell populationQ35618973
The population genetics of Escherichia coliQ40080341
Adaptive evolution of highly mutable loci in pathogenic bacteriaQ40629814
Genetic barriers among bacteria.Q41120565
High mutation frequencies among Escherichia coli and Salmonella pathogensQ48057867
Incidence of mutator strains in Escherichia coli and coliforms in nature.Q54538245
Transposable elements as mutator genes in evolutionQ59084250
Modifiers of mutation rate: a general reduction principleQ69602852
Selective advantage of polA1 mutator over polA+ strains of Escherichia coli in a chemostatQ69905919
Competition growth between Escherichia coli mutL and mut+ in continuously growing culturesQ70186065
Competition between isogenic mutS and mut+ populations of Escherichia coli K12 in continuously growing culturesQ70409687
Host-parasite arms race in mutation modifications: indefinite escalation despite a heavy load?Q71932257
Observations on two types of genetic instability in Escherichia coliQ78790920
P433issue6634
P407language of work or nameEnglishQ1860
P921main subjectadaptive evolutionQ113049937
P304page(s)700-702
P577publication date1997-06-01
P1433published inNatureQ180445
P1476titleRole of mutator alleles in adaptive evolution.
P478volume387

Reverse relations

cites work (P2860)
Q35729697A Genetic Incompatibility Accelerates Adaptation in Yeast
Q37630251A Mobile Element in mutS Drives Hypermutation in a Marine Vibrio
Q33917768A biochemical mechanism for nonrandom mutations and evolution
Q93064899A proofreading-impaired herpesvirus generates populations with quasispecies-like structure
Q36344782A single nucleotide change in mutY increases the emergence of antibiotic-resistant Campylobacter jejuni mutants
Q51489925A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria.
Q59335721Access to high-impact mutations constrains the evolution of antibiotic resistance in soft agar
Q51064794Active causation and the origin of meaning.
Q64933411Adaptive dynamics of unstable cancer populations: The canonical equation.
Q59757712Adaptive mutation in Escherichia coli
Q24623723Adaptive mutation: implications for evolution
Q36369411An analogy between the evolution of drug resistance in bacterial communities and malignant tissues
Q28393123An evolutionary paradigm for carcinogenesis?
Q39448750An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy
Q52007778Analysis of convergence of an evolutionary algorithm with self-adaptation using a stochastic Lyapunov function.
Q44282478Analysis of the Pseudomonas aeruginosa oprD gene from clinical and environmental isolates.
Q34047307Animal Mitochondrial DNA as We Do Not Know It: mt-Genome Organization and Evolution in Nonbilaterian Lineages.
Q41937031Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system.
Q36933558Association between hypermutator phenotype, clinical variables, mucoid phenotype, and antimicrobial resistance in Pseudomonas aeruginosa
Q33992054Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level.
Q33946964Bacteria are different: observations, interpretations, speculations, and opinions about the mechanisms of adaptive evolution in prokaryotes
Q38103942Bacterial genome evolution within a clonal population: from in vitro investigations to in vivo observations
Q37794342Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance
Q90129566Baker's Yeast Clinical Isolates Provide a Model for How Pathogenic Yeasts Adapt to Stress
Q34606746Beneficial mutations, hitchhiking and the evolution of mutation rates in sexual populations
Q28748265Biological species is the only possible form of existence for higher organisms: the evolutionary meaning of sexual reproduction
Q52245251Biomathematics. Merging lines and emerging levels.
Q28727500Cancer in light of experimental evolution
Q33692244Chance favors the prepared genome
Q28247346Chaperonin overexpression promotes genetic variation and enzyme evolution
Q39494379Chromosomal changes during experimental evolution in laboratory populations of Escherichia coli
Q34491552Clinical significance of microbial infection and adaptation in cystic fibrosis
Q24545892Clonal interference and the periodic selection of new beneficial mutations in Escherichia coli
Q33943859Clusters of mutations from transient hypermutability
Q34722064Coevolution with viruses drives the evolution of bacterial mutation rates.
Q35350270Coexistence and within-host evolution of diversified lineages of hypermutable Pseudomonas aeruginosa in long-term cystic fibrosis infections.
Q36914997Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation.
Q35032768Comparative transcriptome analysis of geographically distinct virulent and attenuated Babesia bovis strains reveals similar gene expression changes through attenuation
Q51069725Comparative transcriptomes reveal novel evolutionary strategies adopted by Saccharomyces cerevisiae with improved xylose utilization capability.
Q42379133Competition and fixation of cohorts of adaptive mutations under Fisher geometrical model
Q42736352Competition between high- and higher-mutating strains of Escherichia coli
Q33692357Contingency loci, mutator alleles, and their interactions. Synergistic strategies for microbial evolution and adaptation in pathogenesis
Q36076137Contrasting dynamics of a mutator allele in asexual populations of differing size.
Q41255353Contribution of increased mutagenesis to the evolution of pollutants-degrading indigenous bacteria
Q30869765DNA polymerase active site is highly mutable: evolutionary consequences
Q37109944DNA polymerases in adaptive immunity
Q36071909DNA replication: one strand may be more equal.
Q37627287Darwinism for the Genomic Age: Connecting Mutation to Diversification
Q55162233Death and population dynamics affect mutation rate estimates and evolvability under stress in bacteria.
Q34725734Decay of unused characters by selection and drift
Q50130080Detection of mutator subpopulations in Salmonella typhimurium LT2 by reversion of his alleles
Q42111438Developing controllable hypermutable Clostridium cells through manipulating its methyl-directed mismatch repair system
Q39683024Digital evolution in time-dependent fitness landscapes
Q33991388Direct selection for mutators in Escherichia coli.
Q50056870Distribution of mutation frequencies among Salmonella enterica isolates from animal and human sources and genetic characterization of a Salmonella Heidelberg hypermutator
Q36178618Diversify or die: generation of diversity in response to stress.
Q90148668Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection
Q28247846Dynamics of cancer progression
Q31029779Dynamics of mutator and antibiotic-resistant populations in a pharmacokinetic/pharmacodynamic model of Pseudomonas aeruginosa biofilm treatment.
Q92650977Eco-evolutionary community turnover following environmental change
Q39632553Efflux-pump-derived multiple drug resistance to ethambutol monotherapy in Mycobacterium tuberculosis and the pharmacokinetics and pharmacodynamics of ethambutol
Q92266072Elucidating the functional role of Mycobacterium smegmatis recX in stress response
Q36643853Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast
Q37100886Emergence of species in evolutionary "simulated annealing".
Q52881848Environmental fluctuations do not select for increased variation or population-based resistance in Escherichia coli.
Q35058954Environmental regulation of mutation rates at specific sites.
Q50123026Environmentally constrained mutation and adaptive evolution in Salmonella
Q56902070Enzymes of evolutionary change
Q54517598Equilibrium Distribution of Mutators in the Single Fitness Peak Model
Q76399123Error and repair catastrophes: A two-dimensional phase diagram in the quasispecies model
Q34049897Error‐prone DNA polymerase IV is controlled by the stress‐response sigma factor, RpoS, in Escherichia coli
Q35599902Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity
Q86095467Evaluating evolutionary models of stress-induced mutagenesis in bacteria
Q64104894Evolthon: A community endeavor to evolve lab evolution
Q34082906Evolution and adaptation in Pseudomonas aeruginosa biofilms driven by mismatch repair system-deficient mutators.
Q42741265Evolution of Mutation Rates in Rapidly Adapting Asexual Populations.
Q40877493Evolution of antibiotic resistance
Q28207333Evolution of digital organisms at high mutation rates leads to survival of the flattest
Q33692297Evolution of evolvability.
Q34429727Evolution of high mutation rates in experimental populations of E. coli
Q52568580Evolution of high-level resistance during low-level antibiotic exposure.
Q36456226Evolution of microbial diversity during prolonged starvation
Q28238561Evolution of mutation rates in bacteria
Q24642537Evolution of mutation rates: phylogenomic analysis of the photolyase/cryptochrome family
Q27312240Evolution of mutational robustness in the yeast genome: a link to essential genes and meiotic recombination hotspots
Q33762702Evolution of the linear chromosomal DNA in Streptomyces: is genomic variability developmentally modulated?
Q30243898Evolution, genomics and epidemiology of Pseudomonas syringae: Challenges in Bacterial Molecular Plant Pathology.
Q33949870Evolution-driving genes
Q73592523Evolution: setting the mutation rate
Q34169739Evolution: the evolvability enigma
Q34094904Evolutionary changes in mutation rates and spectra and their influence on the adaptation of pathogens
Q33641954Evolutionary genetics: The economics of mutation
Q79750953Evolutionary genetics: sexually selected mutation rates
Q50117948Evolutionary implications of the frequent horizontal transfer of mismatch repair genes
Q35960653Evolutionary origins of invasive populations
Q59090104Evolving evolvability
Q33837103Evolving mutation rate advances the invasion speed of a sexual species
Q46352624Excess of non-conservative amino acid changes in marine bacterioplankton lineages with reduced genomes.
Q34611032Experimental analysis of molecular events during mutational periodic selections in bacterial evolution.
Q26865383Experimental evolution and the dynamics of genomic mutation rate modifiers
Q64124033Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts
Q24633927Extreme-longevity mutations orchestrate silencing of multiple signaling pathways
Q38616021Fidelity Variants and RNA Quasispecies.
Q38414823Fighting microbial drug resistance: a primer on the role of evolutionary biology in public health
Q34616140Fitness evolution and the rise of mutator alleles in experimental Escherichia coli populations.
Q34575830Fitness landscapes and evolvability
Q41778880Fixation probability of rare nonmutator and evolution of mutation rates
Q95840911Genes and Proteomes Associated With Increased Mutation Frequency and Multidrug Resistance of Naturally Occurring Mismatch Repair-Deficient Salmonella Hypermutators
Q41366386Genetic adaptation of Pseudomonas aeruginosa to the airways of cystic fibrosis patients is catalyzed by hypermutation
Q33963695Genetic analysis of Pseudomonas aeruginosa isolates from the sputa of Australian adult cystic fibrosis patients
Q33804007Genetic instability and darwinian selection in tumours
Q56687584Genetic instability and darwinian selection in tumours
Q40106664Genetic recombinational events in prokaryotes and their viruses: insight into the study of evolution and biodiversity
Q37376525Genome replication engineering assisted continuous evolution (GREACE) to improve microbial tolerance for biofuels production
Q34719336Genomewide screen for modulators of evolvability under toxic antibiotic exposure.
Q64963172Genomic clustering of fitness-affecting mutations favors the evolution of chromosomal instability.
Q55041884Genomic confirmation of nutrient-dependent mutability of mutators in Escherichia coli.
Q40423782Genomic evolution of bacterial populations under coselection by antibiotics and phage
Q33836661Genomics of rapid adaptation to antibiotics: convergent evolution and scalable sequence amplification
Q52136186Hereditary stability and variation in evolution and development.
Q54271627High Recombinant Frequency in Extraintestinal Pathogenic Escherichia coli Strains.
Q39694657High frequency of mutator strains among human uropathogenic Escherichia coli isolates.
Q55285004High mutation rates limit evolutionary adaptation in Escherichia coli.
Q51711564High relatedness selects against hypermutability in bacterial metapopulations.
Q34617567Horizontal acquisition of divergent chromosomal DNA in bacteria: effects of mutator phenotypes
Q34220245Horizontal gene transfer: a critical view
Q34603856Hypermutability in carcinogenesis
Q44350722Hypermutable Staphylococcus aureus strains present at high frequency in subclinical bovine mastitis isolates are associated with the development of antibiotic resistance
Q37922538Hypermutation and stress adaptation in bacteria
Q37598703Hypermutation and the preexistence of antibiotic-resistant Pseudomonas aeruginosa mutants: implications for susceptibility testing and treatment of chronic infections
Q79162727Hypermutation as a Factor Contributing to the Acquisition of Antimicrobial Resistance
Q41974061Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infections
Q89766030Hypermutator Pseudomonas aeruginosa exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis patients
Q40731504Impact of mutS inactivation on foreign DNA acquisition by natural transformation in Pseudomonas stutzeri
Q38241740Implications of new research and technologies for malolactic fermentation in wine.
Q58758641In search of the Goldilocks zone for hybrid speciation
Q35879421In vivo-selected mutations in methyl-directed mismatch repair suppress the virulence attenuation of Salmonella dam mutant strains following intraperitoneal, but not oral, infection of naïve mice
Q93047512Inactivation of a Mismatch-Repair System Diversifies Genotypic Landscape of Escherichia coli During Adaptive Laboratory Evolution
Q42560500Inactivation of the mismatch repair system in Pseudomonas aeruginosa attenuates virulence but favors persistence of oropharyngeal colonization in cystic fibrosis mice.
Q57802932Incompatibilities in Mismatch Repair Genes Contribute to a Wide Range of Mutation Rates in Human Isolates of Baker's Yeast
Q33345237Incompatibilities involving yeast mismatch repair genes: a role for genetic modifiers and implications for disease penetrance and variation in genomic mutation rates
Q39551661Independence of evolutionary and mutational rates after transmission of avian influenza viruses to swine.
Q43181792Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria
Q42574139Inherited and environmentally induced differences in mutation frequencies between wild strains of Sordaria fimicola from "Evolution Canyon".
Q24807229Inter-species horizontal transfer resulting in core-genome and niche-adaptive variation within Helicobacter pylori
Q34102811Interactions among strategies associated with bacterial infection: pathogenicity, epidemicity, and antibiotic resistance
Q42705384Intermediate mutation frequencies favor evolution of multidrug resistance in Escherichia coli
Q33543179Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response
Q89782907Intratumor Heterogeneity and Therapy Resistance: Contributions of Dormancy, Apoptosis Reversal (Anastasis) and Cell Fusion to Disease Recurrence
Q41830947Kick-starting the ratchet: the fate of mutators in an asexual population
Q52682692Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains.
Q39955018Lack of association between hypermutation and antibiotic resistance development in Pseudomonas aeruginosa isolates from intensive care unit patients
Q34420742Lateral and oblique gene transfer
Q28756839Lethal mutagenesis of bacteria
Q37596302Long-term effect of mutagenic DNA repair on accumulation of mutations in Pseudomonas syringae B86-17.
Q37052306Long-term effects of inducible mutagenic DNA repair on relative fitness and phenotypic diversification in Pseudomonas cichorii 302959.
Q90186558Low mutational load and high mutation rate variation in gut commensal bacteria
Q46324175Mechanisms and consequences of diversity-generating immune strategies.
Q38053191Mechanisms and selection of evolvability: experimental evidence.
Q34011353Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B.
Q33847662Mechanisms of stationary phase mutation: a decade of adaptive mutation
Q30754550Microbial astronauts: assembling microbial communities for advanced life support systems
Q34232235Microbial domestication signatures of Lactococcus lactis can be reproduced by experimental evolution.
Q52262067Microbial genetics. The tinkerer's evolving tool-box.
Q22122024Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation
Q55691280Mild environmental stress elicits mutations affecting fitness in Chlamydomonas.
Q48244295Mismatch Repair Incompatibilities in Diverse Yeast Populations
Q43212807Modelling the evolution of genetic instability during tumour progression
Q28647014Molecular Clock of Neutral Mutations in a Fitness-Increasing Evolutionary Process
Q26823667Molecular epidemiology and genomics of group A Streptococcus
Q34117477Mucoidy, quorum sensing, mismatch repair and antibiotic resistance in Pseudomonas aeruginosa from cystic fibrosis chronic airways infections
Q33690962Multiple genetic switches spontaneously modulating bacterial mutability
Q46296390Mutation Rate Evolution in Partially Selfing and Partially Asexual Organisms
Q36590556Mutation accumulation and fitness in mutator subpopulations of Escherichia coli
Q46334331Mutation accumulation under UV radiation in Escherichia coli
Q35869358Mutation as a stress response and the regulation of evolvability
Q41703503Mutation for survival
Q33945503Mutation frequencies and antibiotic resistance
Q33952076Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori
Q36128650Mutation hot spots in yeast caused by long-range clustering of homopolymeric sequences
Q52010693Mutation landscapes.
Q36048167Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.
Q80114206Mutation rate and genome reduction in endosymbiotic and free-living bacteria
Q28710085Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load
Q51327741Mutation rate evolution in replicator dynamics.
Q92752649Mutation rate variability as a driving force in adaptive evolution
Q36885382Mutation rate variation in multicellular eukaryotes: causes and consequences
Q36395099Mutation, recombination, and incipient speciation of bacteria in the laboratory
Q38578737Mutation--The Engine of Evolution: Studying Mutation and Its Role in the Evolution of Bacteria
Q36014236Mutation-Driven Divergence and Convergence Indicate Adaptive Evolution of the Intracellular Human-Restricted Pathogen, Bartonella bacilliformis
Q34550797Mutational spectrum drives the rise of mutator bacteria
Q39646894Mutations in polI but not mutSLH destabilize Haemophilus influenzae tetranucleotide repeats
Q34502921Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family
Q34113782Mutator bacteria as a risk factor in treatment of infectious diseases
Q52043835Mutator dynamics in fluctuating environments.
Q37678002Mutators and hypermutability in bacteria: the Escherichia coli paradigm
Q37247776Mutators and sex in bacteria: conflict between adaptive strategies
Q40507706Mutators in space: the dynamics of high-mutability clones in a two-patch model
Q34607018Mutators, population size, adaptive landscape and the adaptation of asexual populations of bacteria
Q21145371Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapes
Q46527792Network-Based Identification of Adaptive Pathways in Evolved Ethanol-Tolerant Bacterial Populations.
Q37997288New insights into bacterial adaptation through in vivo and in silico experimental evolution
Q33194639Nitrogen-Regulated Hypermutator Strain of Synechococcus sp. for Use in In Vivo Artificial Evolution
Q34232085Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model.
Q46063964Nutrient co-limited Trichodesmium as nitrogen source or sink in a future ocean
Q53395950Nutrient-dependent growth defects and mutability of mutators in Escherichia coli.
Q24794536Occurrence of leu+ revertants under starvation cultures in Escherichia coli is growth-dependent
Q42240703Occurrence of weak mutators among avian pathogenic Escherichia coli (APEC) isolates causing salpingitis and peritonitis in broiler breeders
Q60939386Old Trade, New Tricks: Insights into the Spontaneous Mutation Process from the Partnering of Classical Mutation Accumulation Experiments with High-Throughput Genomic Approaches
Q33667067Optimization of DNA polymerase mutation rates during bacterial evolution
Q54242442Parallel Evolution of High-Level Aminoglycoside Resistance in Escherichia coli Under Low and High Mutation Supply Rates.
Q34351963Parasitic plants have increased rates of molecular evolution across all three genomes
Q36139867Perspective on mutagenesis and repair: the standard model and alternate modes of mutagenesis
Q56431644Phenotypic and Genomic Evolution during a 20,000-Generation Experiment with the Bacterium Escherichia coli
Q36367007Phenotypic heterogeneity promotes adaptive evolution.
Q33307180Phenotypic mutation rates and the abundance of abnormal proteins in yeast
Q28215261Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells
Q35121892Polarisation of prokaryotic chromosomes
Q39005916Population Heterogeneity in Mutation Rate Increases the Frequency of Higher-Order Mutants and Reduces Long-Term Mutational Load.
Q28256131Prokaryotic DNA mismatch repair
Q40166144Rapid and Consistent Evolution of Colistin Resistance in Extensively Drug-Resistant Pseudomonas aeruginosa during Morbidostat Culture
Q51206475Rapid evolution as an ecological process.
Q39492100Rapid evolution of novel traits in microorganisms
Q41722793Rapid in vivo evolution of a beta-lactamase using phagemids
Q37716243Rate and effects of spontaneous mutations that affect fitness in mutator Escherichia coli
Q24548000Rates of spontaneous mutation
Q46838890Reductive genome evolution at both ends of the bacterial population size spectrum.
Q34617476Regulating general mutation rates: examination of the hypermutable state model for Cairnsian adaptive mutation.
Q34434306Regulation of mutY and nature of mutator mutations in Escherichia coli populations under nutrient limitation
Q55067610Retroviruses, ascorbate, and mutations, in the evolution of Homo sapiens.
Q36843864Robustness promotes evolvability of thermotolerance in an RNA virus
Q42012937Role of DNA base excision repair in the mutability and virulence of Streptococcus mutans
Q44034811Role of a short tandem leucine/arginine repeat in strong mutator phenotype acquisition in a clinical isolate of Salmonella Typhimurium
Q33975727Role of genomic typing in taxonomy, evolutionary genetics, and microbial epidemiology
Q42754912Role of mutS and mutL genes in hypermutability and recombination in Staphylococcus aureus
Q21144990SOS response induces persistence to fluoroquinolones in Escherichia coli
Q37197670Saccharomyces cerevisiae: a sexy yeast with a prion problem
Q45950358Second-order cooperation: Cooperative offspring as a living public good arising from second-order selection on non-cooperative individuals.
Q34203956Second-order selection in bacterial evolution: selection acting on mutation and recombination rates in the course of adaptation
Q55003119Selection and Neutral Mutations Drive Pervasive Mutability Losses in Long-Lived Anti-HIV B-Cell Lineages.
Q38201509Selection of antibiotic resistance at very low antibiotic concentrations
Q37028295Self-structuring in spatial evolutionary ecology
Q73423086Sequence variation in Helicobacter pylori
Q36660289Sexual selection and the evolution of evolvability.
Q24799773Sexual selection, germline mutation rate and sperm competition
Q37406333Side effects of antibiotics on genetic variability.
Q51148036Sign of selection on mutation rate modifiers depends on population size.
Q33846180Significance of multiple mutations in cancer
Q36474342Spontaneously Arising mutL Mutators in Evolving Escherichia coli Populations Are the Result of Changes in Repeat Length
Q35544150Stationary phase mutagenesis: mechanisms that accelerate adaptation of microbial populations under environmental stress
Q35986593Stress responses and genetic variation in bacteria.
Q34504117Stress-induced evolution and the biosafety of genetically modified microorganisms released into the environment
Q51052567Stress-induced mutagenesis and complex adaptation.
Q36961683Stress-induced mutagenesis in bacteria.
Q41200966Stress-induced mutagenesis: Stress diversity facilitates the persistence of mutator genes
Q30327563Superbugs: How They Evolve and Minimize the Cost of Resistance.
Q37571299Supra-operonic clusters of functionally related genes (SOCs) are a source of horizontal gene co-transfers
Q51168768Temperature effects on life-history trade-offs, germline maintenance and mutation rate under simulated climate warming.
Q22122206The Beagle in a bottle
Q40615967The CRISPR case, « ready-made » mutations and Lamarckian evolution of an adaptive immunity system
Q29301497The Evolution of Mutation Rate in Finite Asexual Populations
Q92857979The Mutator Phenotype: Adapting Microbial Evolution to Cancer Biology
Q47100798The Red Queen and King in finite populations
Q90038371The SNAP hypothesis: Chromosomal rearrangements could emerge from positive Selection during Niche Adaptation
Q35077947The advantage of arriving first: characteristic times in finite size populations of error-prone replicators
Q73373285The approach to mutation-selection balance in an infinite asexual population, and the evolution of mutation rates
Q38517985The balance between mutators and nonmutators in asexual populations
Q54222557The complexities of viral mutation rates.
Q34609052The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness
Q43560044The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable
Q38953067The conserved phylogeny of blood microbiome
Q55430533The cost of replication fidelity in human immunodeficiency virus type 1.
Q33692274The distribution of rates of spontaneous mutation over viruses, prokaryotes, and eukaryotes
Q35115441The dynamics of repeated elements: applications to the epidemiology of tuberculosis.
Q36004587The ecology of the genome - mobile DNA elements and their hosts
Q64056369The effect of bacterial mutation rate on the evolution of CRISPR-Cas adaptive immunity
Q33763823The effect of population bottlenecks on mutation rate evolution in asexual populations
Q22065663The emergence of antibiotic resistance by mutation
Q54652456The evolution of bacterial mutation rates under simultaneous selection by interspecific and social parasitism.
Q34617981The evolution of mutator genes in bacterial populations: the roles of environmental change and timing.
Q34285727The evolution of stress-induced hypermutation in asexual populations
Q37152739The fixation probability of rare mutators in finite asexual populations.
Q38304923The frequency of mutators in populations of Escherichia coli
Q44935797The generation of multiple co-existing mal-regulatory mutations through polygenic evolution in glucose-limited populations of Escherichia coli
Q54525605The influence of cellular physiology on the initiation of mutational pathways inEscherichia colipopulations
Q34611553The influence of hitchhiking and deleterious mutation upon asexual mutation rates
Q35362334The lower bound to the evolution of mutation rates
Q28492576The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutants
Q42758515The mutL mutation in Pseudomonas aeruginosa isolates reveals multidrug-resistant traits and possible evolutionary trends
Q74481910The mutation rate and cancer
Q41862731The optimal burst of mutation to create a phenotype
Q35885995The properties of spontaneous mutations in the opportunistic pathogen Pseudomonas aeruginosa
Q24619467The rate of establishment of complex adaptations
Q37323963The rich phase structure of a mutator model.
Q36098286The rise and spread of a new pathogen: seroresistant Moraxella catarrhalis
Q41613054The role of genomics in studying genetic susceptibility to infectious disease
Q35177659The role of mutators in the emergence of antibiotic-resistant bacteria
Q27011463The role of robustness in phenotypic adaptation and innovation
Q34330675The speed of evolution and maintenance of variation in asexual populations
Q37120152Thioridazine as Chemotherapy for Mycobacterium avium Complex Diseases
Q42248684Time-Resolved Tracking of Mutations Reveals Diverse Allele Dynamics during Escherichia coli Antimicrobial Adaptive Evolution to Single Drugs and Drug Pairs.
Q50132690To be a mutator, or how pathogenic and commensal bacteria can evolve rapidly
Q34603730Transient and heritable mutators in adaptive evolution in the lab and in nature
Q53428207Transient appearance of the mutator phenotype during carcinogenesis as a possible explanation for the lack of mini/microsatellite instability in many late stage tumors.
Q34220343Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution.
Q34974987Tuberculosis chemotherapy: the influence of bacillary stress and damage response pathways on drug efficacy
Q40711295Ultra Deep Sequencing of a Baculovirus Population Reveals Widespread Genomic Variations
Q60535165Urbanization erodes ectomycorrhizal fungal diversity and may cause microbial communities to converge.
Q51302402Viral mutation rates: modelling the roles of within-host viral dynamics and the trade-off between replication fidelity and speed.
Q43514301Virus mutators and antimutators: roles in evolution, pathogenesis and emergence
Q38665569Weak mutators can drive the evolution of fluoroquinolone resistance in Escherichia coli
Q28536445Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients
Q28072013Within-host evolution of bacterial pathogens