Rapid in vivo evolution of a beta-lactamase using phagemids

scientific article published on April 2000

Rapid in vivo evolution of a beta-lactamase using phagemids is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/(SICI)1097-0290(20000405)68:1<121::AID-BIT15>3.0.CO;2-X
P698PubMed publication ID10699880

P2093author name stringSchellenberger V
Liu AD
Long-McGie J
P2860cites workRapid evolution of a protein in vitro by DNA shufflingQ28245873
Evolution of high mutation rates in experimental populations of E. coliQ34429727
Development of test panel of beta-lactamases expressed in a common Escherichia coli host background for evaluation of new beta-lactam antibioticsQ35111391
TEM-4, a new plasmid-mediated beta-lactamase that hydrolyzes broad-spectrum cephalosporins in a clinical isolate of Escherichia coliQ35360336
Isolation of a thermostable enzyme variant by cloning and selection in a thermophileQ35587822
Amino acid sequence determinants of beta-lactamase structure and activityQ36799732
Extended-spectrum plasmid-mediated beta-lactamasesQ40936228
Role of mutator alleles in adaptive evolution.Q54564129
The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamaseQ56902347
Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strainQ71397837
P433issue1
P304page(s)121-125
P577publication date2000-04-01
P1433published inBiotechnology and BioengineeringQ4915339
P1476titleRapid in vivo evolution of a beta-lactamase using phagemids
P478volume68

Reverse relations

cites work (P2860)
Q46540264Evolutionary engineering of mixed-sugar utilization by a xylose-fermenting Saccharomyces cerevisiae strain
Q40677633Evolutionary potential of an RNA virus
Q44957101Experimental evolution of gene duplicates in a bacterial plasmid model
Q39792503Haemophilus influenzae bla(ROB-1) mutations in hypermutagenic deltaampC Escherichia coli conferring resistance to cefotaxime and beta-lactamase inhibitors and increased susceptibility to cefaclor
Q34548635Multiple Global Suppressors of Protein Stability Defects Facilitate the Evolution of Extended-Spectrum TEM β-Lactamases
Q37735903Natural evolution of TEM-1 β-lactamase: experimental reconstruction and clinical relevance
Q28477196Network models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectories
Q34614621Predicting evolutionary potential: in vitro evolution accurately reproduces natural evolution of the tem beta-lactamase
Q40744300Prolonged maltose-limited cultivation of Saccharomyces cerevisiae selects for cells with improved maltose affinity and hypersensitivity
Q39492100Rapid evolution of novel traits in microorganisms
Q35813374Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I.
Q22065663The emergence of antibiotic resistance by mutation

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