The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable

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The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M011472200
P698PubMed publication ID11278911

P2093author name stringLoeb LA
Patel PH
Shinkai A
P2860cites workA rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMPQ27728960
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTPQ27729369
Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanismQ27729370
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69Q27740210
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolutionQ27748814
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistanceQ27766086
A constant rate of spontaneous mutation in DNA-based microbesQ28271032
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitorQ29547710
DNA replication fidelityQ29616841
Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.Q29616842
DNA polymerases: structural diversity and common mechanismsQ29619403
Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I.Q30400206
DNA polymerase active site is highly mutable: evolutionary consequencesQ30869765
Multiple amino acid substitutions allow DNA polymerases to synthesize RNA.Q30929263
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.Q34508854
Proliferation of mutators in A cell populationQ35618973
Detection of the catalytic activities of DNA polymerases and their associated exonucleases following SDS-polyacrylamide gel electrophoresisQ35707068
A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotidesQ36000833
The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidanceQ36099918
Overproduction of DnaE protein (alpha subunit of DNA polymerase III) restores viability in a conditionally inviable Escherichia coli strain deficient in DNA polymerase IQ36112741
High-copy-number and low-copy-number plasmid vectors for lacZ alpha-complementation and chloramphenicol- or kanamycin-resistance selectionQ36448348
An attempt to unify the structure of polymerasesQ41204694
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.Q41728302
A general structure for DNA-dependent DNA polymerases.Q43654996
Role of mutator alleles in adaptive evolution.Q54564129
DNA polymerases on the moveQ74164952
How E. coli DNA polymerase I (Klenow fragment) distinguishes between deoxy- and dideoxynucleotidesQ74507055
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)18836-18842
P577publication date2001-03-12
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable
P478volume276

Reverse relations

cites work (P2860)
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Q34142849Genome instability due to ribonucleotide incorporation into DNA.
Q33273825Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I.
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Q26747256Modified Nucleoside Triphosphates for In-vitro Selection Techniques
Q28245001Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis
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Q37011650Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity
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Q28303047Unlocking the sugar "steric gate" of DNA polymerases

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