Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity

scientific article published on April 2004

Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.24.7.2734-2746.2004
P932PMC publication ID371111
P698PubMed publication ID15024063
P5875ResearchGate publication ID8677223

P50authorEric T. KoolQ30323358
P2093author name stringChikahide Masutani
Fumio Hanaoka
Shigenori Iwai
Motoshi Suzuki
Yukihiro Nishiyama
Shonen Yoshida
Siripan Limsirichaikul
Atsuko Niimi
P2860cites workMutations of Bacteria from Virus Sensitivity to Virus ResistanceQ24533278
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Sequence of a yeast DNA fragment containing a chromosomal replicator and the TRP1 geneQ48413159
Low fidelity DNA synthesis by human DNA polymerase-etaQ50335566
A table for the estimation of the spontaneous mutations rate of cells in cultureQ52957251
Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I.Q54567474
A specific partner for abasic damage in DNAQ59049012
Phi 29 DNA polymerase active site. The conserved amino acid motif "Kx3NSxYG" is involved in template-primer binding and dNTP selectionQ63384211
Differential extension of 3' mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-alphaQ69293401
The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiaeQ72240900
MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiaeQ73075608
Specific amino acid changes enhance the anti-recombination activity of the UmuD'C complexQ73665085
Defective DNA polymerase-delta proofreading causes cancer susceptibility in miceQ73954766
Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helixQ74036849
Getting a grip on how DNA polymerases functionQ74266456
Requirement of DNA polymerase activity of yeast Rad30 protein for its biological functionQ77808091
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesisQ27939891
Error rate and specificity of human and murine DNA polymerase etaQ28216092
Translesion synthesis by human DNA polymerase eta across thymine glycol lesionsQ28216674
Pathway correcting DNA replication errors in Saccharomyces cerevisiaeQ28263175
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zetaQ28354217
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreadingQ28510929
DNA replication fidelityQ29616841
Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.Q29616842
DNA polymerases: structural diversity and common mechanismsQ29619403
Prokaryotic DNA polymerase I: evolution, structure, and "base flipping" mechanism for nucleotide selectionQ30667746
Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alphaQ30897941
The role of mismatch repair in the prevention of base pair mutations in Saccharomyces cerevisiaeQ33592366
The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiaeQ33957467
DNA mismatch repair and genetic instabilityQ34090778
Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypassQ35037436
Checkpoint activation regulates mutagenic translesion synthesisQ35963618
A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repairQ36553838
Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structureQ36817752
Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins.Q38293922
Pyrene nucleotide as a mechanistic probe: evidence for a transient abasic site-like intermediate in the bypass of dipyrimidine photoproducts by T7 DNA polymeraseQ38306436
The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase alpha is important in discriminating correct deoxyribonucleotides from incorrect onesQ38356754
Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repairQ39449001
Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase deltaQ39455847
Mutator phenotype induced by aberrant replicationQ39610863
Fidelity of DNA synthesisQ40113209
Compilation, alignment, and phylogenetic relationships of DNA polymerasesQ40405362
Biochemical basis of DNA replication fidelityQ40903454
A single highly mutable catalytic site amino acid is critical for DNA polymerase fidelityQ43509472
The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutableQ43560044
O-helix mutant T664P of Thermus aquaticus DNA polymerase I: altered catalytic properties for incorporation of incorrect nucleotides but not correct nucleotidesQ43603086
Fidelity studies of the human DNA polymerase alpha. The most conserved region among alpha-like DNA polymerases is responsible for metal-induced infidelity in DNA synthesis.Q43757735
In vivo mutagenesis by Escherichia coli DNA polymerase I. Ile(709) in motif A functions in base selection.Q43767918
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta.Q44367170
Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coliQ45771082
Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptaseQ46193418
Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutantsQ46691965
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)2734-2746
P577publication date2004-04-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titlePalm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity
P478volume24

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cites work (P2860)
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