Role of DNA polymerases in repeat-mediated genome instability

scientific article published on 8 November 2012

Role of DNA polymerases in repeat-mediated genome instability is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2012.10.006
P932PMC publication ID3513503
P698PubMed publication ID23142667
P5875ResearchGate publication ID233394875

P50authorSergei MirkinQ11256582
Irina VoineaguQ61305425
P2093author name stringYouri I Pavlov
Polina V Shcherbakova
Alexander A Shishkin
Kartik A Shah
P2860cites workPCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}.Q37482417
Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide poolsQ37483304
Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genesQ37599112
Repeat instability as the basis for human diseases and as a potential target for therapyQ37696952
Timing and spacing of ubiquitin‐dependent DNA damage bypassQ37878585
Replication stalling at Friedreich's ataxia (GAA)n repeats in vivo.Q40633778
Intrinsic coupling of lagging-strand synthesis to chromatin assembly.Q41457868
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repairQ42556770
Large-scale expansions of Friedreich's ataxia GAA repeats in yeastQ43077169
Patching broken chromosomes with extranuclear cellular DNAQ64388709
Trinucleotide repeat expansion and human diseaseQ71576495
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase deltaQ24601494
Advances in mechanisms of genetic instability related to hereditary neurological diseasesQ24816457
DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiaeQ27929803
Increased mutagenesis and unique mutation signature associated with mitotic gene conversionQ27934880
DNA polymerases at the eukaryotic fork-20 years laterQ28255094
A constant rate of spontaneous mutation in DNA-based microbesQ28271032
Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansionQ28275699
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zetaQ28354217
Trinucleotide Repeat DisordersQ29038716
Eukaryotic translesion synthesis DNA polymerases: specificity of structure and functionQ29617871
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins.Q33257520
Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiaeQ33628462
Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t)Q33786528
The Friedreich ataxia GAA triplet repeat: premutation and normal alleles.Q34435679
Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast.Q34582933
Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.Q34606865
The effect of DNA replication mutations on CAG tract stability in yeast.Q34607157
A novel function of DNA polymerase zeta regulated by PCNA.Q35040027
Mechanisms of trinucleotide repeat instability during human developmentQ35219284
Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative diseaseQ35547560
Replication fork dynamics and dynamic mutations: the fork-shift model of repeat instabilityQ36105938
DNA structures, repeat expansions and human hereditary disorders.Q36483404
Expandable DNA repeats and human disease.Q36854284
Instability and chromatin structure of expanded trinucleotide repeatsQ36900707
Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activityQ37011650
Features of trinucleotide repeat instability in vivoQ37048169
Dividing the workload at a eukaryotic replication forkQ37149735
P433issue5
P921main subjectgenome stabilityQ98655700
P304page(s)1088-1095
P577publication date2012-11-08
P1433published inCell ReportsQ5058165
P1476titleRole of DNA polymerases in repeat-mediated genome instability
P478volume2

Reverse relations

cites work (P2860)
Q42623262A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)n Repeats Associated with Friedreich's Ataxia
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