PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}.

scientific article published on 11 March 2009

PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/JB/MVP043
P932PMC publication ID3892766
P698PubMed publication ID19279190

P2093author name stringJiro Usukura
Takashi Takahashi
Motoshi Suzuki
Takashi Murate
Shuta Tomida
Takashi Hishida
Akihiko Kikuchi
Siripan Limsirichaikul
Shunji Izuta
Yoshiyuki Nakagawa
Tomohiro Akashi
Yasutomo Itoh
Qin Miao Huang
Atsuko Niimi
Youri Pavlov
P2860cites workRoles of DNA polymerases in replication, repair, and recombination in eukaryotes.Q36687824
Translesion synthesis: Y-family polymerases and the polymerase switchQ36760898
Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activityQ37011650
Replication protein-A mediates the association of calf thymus DNA polymerase alpha-DNA primase complex with guanine-rich DNA sequenceQ38352495
Evidence for Preferential Mismatch Repair of Lagging Strand DNA Replication Errors in YeastQ38355096
The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase alpha is important in discriminating correct deoxyribonucleotides from incorrect onesQ38356754
Microsatellite instability and mismatch repair target gene mutations in cell lines and xenografts of prostate cancerQ40334710
Genetic and cellular characterizations of human TCF4 with microsatellite instability in colon cancer and leukemia cell lines.Q40420164
ATP utilization by yeast replication factor C. II. Multiple stepwise ATP binding events are required to load proliferating cell nuclear antigen onto primed DNA.Q43658431
Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase deltaQ46848079
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities.Q50645182
Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability.Q53989253
Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I.Q54567474
Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV LesionsQ58883733
Branch Migrating Sister Chromatid Junctions Form at Replication Origins through Rad51/Rad52-Independent MechanismsQ58883735
Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumoursQ63407701
Deoxypyrimidine cluster mediates the priming by calf thymus DNA primase subunitQ72079926
DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiaeQ73406613
Frameshift mutations in caspase-5 and other target genes in leukemia and lymphoma cell lines having microsatellite instabilityQ78804736
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase deltaQ82346662
DNA replication fidelity: proofreading in transQ82872821
Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7Q24291530
Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forksQ24314325
Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesisQ24594244
The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instabilityQ24606412
Yeast DNA polymerase epsilon participates in leading-strand DNA replicationQ24652913
Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a.Q27930823
exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repairQ27935389
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.Q27937465
Functional and physical interaction of yeast Mgs1 with PCNA: impact on RAD6-dependent DNA damage toleranceQ27938957
Error rate and specificity of human and murine DNA polymerase etaQ28216092
Interaction of hREV1 with three human Y-family DNA polymerasesQ28266239
Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 proteinQ28510960
Eukaryotic translesion synthesis DNA polymerases: specificity of structure and functionQ29617871
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugationQ29619155
Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alphaQ30897941
Eukaryotic DNA polymerases: proposal for a revised nomenclature.Q34093113
Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1Q34234530
Eukaryotic mutagenesis and translesion replication dependent on DNA polymerase zeta and Rev1 proteinQ34253002
Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesisQ34597716
Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affairQ34770150
Cellular roles of DNA polymerase zeta and Rev1 proteinQ35037431
A novel function of DNA polymerase zeta regulated by PCNA.Q35040027
Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta.Q35728727
ATP-dependent structural change of the eukaryotic clamp-loader protein, replication factor C.Q35835905
Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregationQ35938214
Mutator alleles of yeast DNA polymerase zeta.Q36247787
RNA priming coupled with DNA synthesis on natural template by calf thymus DNA polymerase alpha-primase.Q36673277
P433issue1
P921main subjectprotein ubiquitinationQ3547638
P304page(s)13-21
P577publication date2009-03-11
P1433published inJournal of BiochemistryQ6294839
P1476titlePCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}.
P478volume146

Reverse relations

cites work (P2860)
Q28255094DNA polymerases at the eukaryotic fork-20 years later
Q35156821Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 Complex
Q35834445Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing
Q92479421Large-scale contractions of Friedreich's ataxia GAA repeats in yeast occur during DNA replication due to their triplex-forming ability
Q42248736Mcm10 deficiency causes defective-replisome-induced mutagenesis and a dependency on error-free postreplicative repair.
Q36365706PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast
Q33628462Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae
Q53062576Proper functioning of the GINS complex is important for the fidelity of DNA replication in yeast.
Q42383457Role of DNA polymerases in repeat-mediated genome instability
Q41868005The genome maintenance factor Mgs1 is targeted to sites of replication stress by ubiquitylated PCNA.
Q42467404The role of DNA polymerase alpha in the control of mutagenesis in Saccharomyces cerevisiae cells starved for nutrients

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