| scholarly article | Q13442814 |
| P50 | author | Dmitry A. Gordenin | Q55130852 |
| Michael A Resnick | Q62124589 | ||
| P2093 | author name string | P M Burgers | |
| T A Kunkel | |||
| R Obert | |||
| Y H Jin | |||
| P2860 | cites work | Mutations in RAD27 define a potential link between G1 cyclins and DNA replication | Q40016855 |
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| Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing | Q59444619 | ||
| A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair | Q64389285 | ||
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| Evidence favouring the hypothesis of a conserved 3'-5' exonuclease active site in DNA-dependent DNA polymerases | Q68079183 | ||
| Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase | Q70158810 | ||
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| DNA polymerase from Saccharomyces cerevisiae | Q70984801 | ||
| The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae | Q72240900 | ||
| Analysis of the Okazaki fragment distributions along single long DNAs replicated by the bacteriophage T4 proteins | Q73221711 | ||
| The Schizosaccharomyces pombe cdc6 gene encodes the catalytic subunit of DNA polymerase delta | Q73235287 | ||
| Overexpression of multisubunit replication factors in yeast | Q78150997 | ||
| Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance | Q22009967 | ||
| Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex | Q27620076 | ||
| Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease | Q27930354 | ||
| The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication | Q27933493 | ||
| Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein | Q27933995 | ||
| The DNA replication fork in eukaryotic cells. | Q27939216 | ||
| New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae | Q28131599 | ||
| Replication fork pausing and recombination or "gimme a break" | Q28142854 | ||
| Pathway correcting DNA replication errors in Saccharomyces cerevisiae | Q28263175 | ||
| Gene expression of flap endonuclease-1 during cell proliferation and differentiation | Q28565438 | ||
| Enzymes and reactions at the eukaryotic DNA replication fork | Q28610363 | ||
| DNA polymerase delta, an essential enzyme for DNA transactions | Q28610365 | ||
| Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1 | Q28645598 | ||
| Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination | Q29615272 | ||
| DNA replication fidelity | Q29616841 | ||
| DNA polymerases: structural diversity and common mechanisms | Q29619403 | ||
| Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair | Q31505231 | ||
| Plant homologue of flap endonuclease-1: molecular cloning, characterization, and evidence of expression in meristematic tissues | Q33334586 | ||
| Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t) | Q33786528 | ||
| The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae | Q33957467 | ||
| Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations. | Q33957827 | ||
| A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk. | Q33958881 | ||
| Recombination factors of Saccharomyces cerevisiae | Q33984330 | ||
| Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA | Q33994195 | ||
| DNA Polymerase Fidelity: From Genetics Toward a Biochemical Understanding | Q34603989 | ||
| Factors Affecting Inverted Repeat Stimulation of Recombination and Deletion in Saccharomyces cerevisiae | Q34604021 | ||
| Regulation of DNA Polymerase Exonucleolytic Proofreading Activity: Studies of Bacteriophage T4 “Antimutator” DNA Polymerases | Q34604145 | ||
| Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast. | Q34606865 | ||
| Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes. | Q36555338 | ||
| Suppressors of thermosensitive mutations in the DNA polymerase delta gene of Saccharomyces cerevisiae | Q36716530 | ||
| DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies | Q37442754 | ||
| Mutants in the Exo I motif of Escherichia coli dnaQ: defective proofreading and inviability due to error catastrophe | Q37678547 | ||
| Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency | Q38320553 | ||
| Structure and Processivity of Two Forms of Saccharomyces cerevisiae DNA Polymerase δ | Q38335236 | ||
| Homologous recombination is required for the viability of rad27 mutants | Q39726024 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | genome stability | Q98655700 |
| P304 | page(s) | 5122-5127 | |
| P577 | publication date | 2001-04-17 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability | |
| P478 | volume | 98 |
| Q36464280 | 3' to 5' exonuclease activity of herpes simplex virus type 1 DNA polymerase modulates its strand displacement activity |
| Q41990410 | A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading |
| Q24814638 | A network of multi-tasking proteins at the DNA replication fork preserves genome stability |
| Q61124737 | A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme |
| Q28534685 | A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability |
| Q21558766 | Activation of an alternative, rec12 (spo11)-independent pathway of fission yeast meiotic recombination in the absence of a DNA flap endonuclease |
| Q54092693 | Analysis of DNA replication intermediates suggests mechanisms of repeat sequence expansion |
| Q44294677 | Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion |
| Q27024636 | Antimutator variants of DNA polymerases |
| Q36593752 | Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis. |
| Q37142738 | Cadmium is a mutagen that acts by inhibiting mismatch repair. |
| Q73420352 | Characterization of mutations that are synthetic lethal with pol3-13, a mutated allele of DNA polymerase delta in Saccharomyces cerevisiae |
| Q36846071 | Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae |
| Q35616094 | Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity |
| Q34421580 | Computational protein design suggests that human PCNA-partner interactions are not optimized for affinity. |
| Q35079299 | Considering the cancer consequences of altered DNA polymerase function |
| Q38037373 | DNA Polymerase ε |
| Q63384098 | DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in |
| Q38290311 | DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro |
| Q26991961 | DNA polymerase delta in dna replication and genome maintenance |
| Q36961060 | DNA polymerase epsilon: a polymerase of unusual size (and complexity). |
| Q89983002 | DNA polymerase δ proofreads errors made by DNA polymerase ε |
| Q26822699 | DNA polymerase ε and its roles in genome stability |
| Q28287769 | DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer |
| Q28255094 | DNA polymerases at the eukaryotic fork-20 years later |
| Q36090978 | DNA polymerases that propagate the eukaryotic DNA replication fork |
| Q28295863 | DNA replication fidelity and cancer |
| Q24630816 | DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination |
| Q48845921 | Direct Visualization of RNA-DNA Primer Removal from Okazaki Fragments Provides Support for Flap Cleavage and Exonucleolytic Pathways in Eukaryotic Cells. |
| Q55025484 | Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair. |
| Q28277921 | Division of labor at the eukaryotic replication fork |
| Q59128954 | Dna2 processes behind the fork long ssDNA flaps generated by Pif1 and replication-dependent strand displacement |
| Q24805912 | Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase |
| Q24798598 | Enzymatic properties of the Caenorhabditis elegans Dna2 endonuclease/helicase and a species-specific interaction between RPA and Dna2 |
| Q34520066 | Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta |
| Q36115776 | Evidence that the DNA mismatch repair system removes 1-nucleotide Okazaki fragment flaps |
| Q28248149 | Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication |
| Q36447527 | FEN nucleases: bind, bend, fray, cut. |
| Q33670045 | FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells |
| Q35183869 | Flap endonuclease 1: a novel tumour suppresser protein |
| Q36990200 | Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis |
| Q35834445 | Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing |
| Q34098053 | Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression |
| Q47766916 | Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro |
| Q24560006 | Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication |
| Q53153858 | In vitro reconstitution of RNA primer removal in Archaea reveals the existence of two pathways |
| Q34442824 | Kinetic Approaches to Understanding the Mechanisms of Fidelity of the Herpes Simplex Virus Type 1 DNA Polymerase |
| Q92479421 | Large-scale contractions of Friedreich's ataxia GAA repeats in yeast occur during DNA replication due to their triplex-forming ability |
| Q34427479 | Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease |
| Q38331739 | Maturation of bacteriophage T4 lagging strand fragments depends on interaction of T4 RNase H with T4 32 protein rather than the T4 gene 45 clamp |
| Q28294940 | Mechanism of trinucleotide repeats instabilities: the necessities of repeat non-B secondary structure formation and the roles of cellular trans-acting factors |
| Q27937434 | Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε. |
| Q37483304 | Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools |
| Q36836977 | Mutagenic and recombinagenic responses to defective DNA polymerase delta are facilitated by the Rev1 protein in pol3-t mutants of Saccharomyces cerevisiae |
| Q39646894 | Mutations in polI but not mutSLH destabilize Haemophilus influenzae tetranucleotide repeats |
| Q42797357 | Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication |
| Q34055320 | Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast |
| Q35661319 | Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability |
| Q28214427 | Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick |
| Q24632622 | Okazaki fragment maturation: nucleases take centre stage |
| Q64231032 | PCNA accelerates the nucleotide incorporation rate by DNA polymerase δ |
| Q37482417 | PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}. |
| Q33358808 | Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal |
| Q24653831 | Polymerase dynamics at the eukaryotic DNA replication fork |
| Q34994597 | Polymorphisms in DNA repair and environmental interactions |
| Q33964152 | Processing of lagging-strand intermediates in vitro by herpes simplex virus type 1 DNA polymerase |
| Q35734815 | Quantifying the contributions of base selectivity, proofreading and mismatch repair to nuclear DNA replication in Saccharomyces cerevisiae |
| Q33255508 | RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase delta. |
| Q27938925 | Reconstituted Okazaki fragment processing indicates two pathways of primer removal |
| Q28205766 | Reconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme |
| Q38638250 | Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast |
| Q35562105 | Regulation of yeast DNA polymerase δ-mediated strand displacement synthesis by 5'-flaps |
| Q39421725 | Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy |
| Q28258327 | Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans |
| Q36873034 | Resolving individual steps of Okazaki-fragment maturation at a millisecond timescale |
| Q36391187 | Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA. |
| Q37628288 | Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity |
| Q36687824 | Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. |
| Q36316468 | S-phase checkpoint pathways stimulate the mobility of the retrovirus-like transposon Ty1. |
| Q46554910 | Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions. |
| Q28242820 | Sensitivity to phosphonoacetic acid: a new phenotype to probe DNA polymerase delta in Saccharomyces cerevisiae. |
| Q27938722 | Single strand annealing and ATP-independent strand exchange activities of yeast and human DNA2: possible role in Okazaki fragment maturation |
| Q27935769 | Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy. |
| Q28475748 | Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair |
| Q35691498 | The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication |
| Q33300908 | The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA. |
| Q41883034 | The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication. |
| Q24630867 | The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases |
| Q47391938 | The importance of an interaction network for proper DNA polymerase ζ heterotetramer activity. |
| Q35064113 | The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis |
| Q21144935 | The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved |
| Q35219919 | The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers |
| Q27932484 | The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains |
| Q27938619 | The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae |
| Q34614165 | The roles of Klenow processing and flap processing activities of DNA polymerase I in chromosome instability in Escherichia coli K12 strains |
| Q35550042 | Trinucleotide repeat instability: a hairpin curve at the crossroads of replication, recombination, and repair |
| Q44114984 | Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks |
| Q47148057 | Whole Genome Sequence Analysis of Mutations Accumulated in rad27Δ Yeast Strains with Defects in the Processing of Okazaki Fragments Indicates Template-Switching Events |
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