| scholarly article | Q13442814 |
| P50 | author | Cynthia T McMurray | Q88307093 |
| P2093 | author name string | Craig Spiro | |
| P2860 | cites work | Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells | Q22003975 |
| Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300 | Q24291379 | ||
| Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity | Q24291787 | ||
| The characterization of a mammalian DNA structure-specific endonuclease | Q24336672 | ||
| Essential amino acids for substrate binding and catalysis of human flap endonuclease 1 | Q24336892 | ||
| Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). | Q24532243 | ||
| The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability | Q24606412 | ||
| Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK | Q24609992 | ||
| Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen | Q27931829 | ||
| Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae | Q28140402 | ||
| A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy | Q28142117 | ||
| Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats | Q28142629 | ||
| Genetic analysis of BRCA1 function in a defined tumor cell line | Q28142643 | ||
| Functional analysis of human FEN1 in Saccharomyces cerevisiae and its role in genome stability | Q28146137 | ||
| Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair | Q28198657 | ||
| Homologous regions of Fen1 and p21Cip1 compete for binding to the same site on PCNA: a potential mechanism to co-ordinate DNA replication and repair | Q28240258 | ||
| Trinucleotide repeats that expand in human disease form hairpin structures in vitro | Q28301826 | ||
| Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice | Q28505404 | ||
| Gene expression of flap endonuclease-1 during cell proliferation and differentiation | Q28565438 | ||
| Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1 | Q28645598 | ||
| A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells | Q29547557 | ||
| Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice | Q29615357 | ||
| Molecular mechanism of nucleotide excision repair. | Q30669716 | ||
| Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair | Q31505231 | ||
| DNA secondary structure: a common and causative factor for expansion in human disease | Q33537493 | ||
| Nucleotide excision repair and human syndromes | Q33846209 | ||
| Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins | Q33857767 | ||
| A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk. | Q33958881 | ||
| Novel function of Rad27 (FEN-1) in restricting short-sequence recombination | Q33967784 | ||
| Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage | Q33968982 | ||
| Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression | Q34098053 | ||
| Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism | Q34613942 | ||
| Functional analysis of point mutations in human flap endonuclease-1 active site | Q34633807 | ||
| A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events | Q34988376 | ||
| Role of ERCC1 in removal of long non-homologous tails during targeted homologous recombination | Q35116728 | ||
| Different mechanisms underlie DNA instability in Huntington disease and colorectal cancer | Q35238626 | ||
| Orientation dependence of trinucleotide CAG repeat instability in Saccharomyces cerevisiae | Q36563938 | ||
| Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA. | Q36699598 | ||
| DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro | Q38290311 | ||
| Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin | Q39688114 | ||
| Homologous recombination is required for the viability of rad27 mutants | Q39726024 | ||
| Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome | Q40021880 | ||
| Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae | Q40022432 | ||
| Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease. | Q40704833 | ||
| Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex | Q40749079 | ||
| Xrcc3 is required for assembly of Rad51 complexes in vivo | Q41016235 | ||
| Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier. | Q41017582 | ||
| The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair | Q41396267 | ||
| Processing of UV damage in vitro by FEN-1 proteins as part of an alternative DNA excision repair pathway | Q41645407 | ||
| Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA. | Q41676798 | ||
| Fen1 expression: a novel marker for cell proliferation | Q42816724 | ||
| Stimulation of eukaryotic flap endonuclease-1 activities by proliferating cell nuclear antigen (PCNA) is independent of its in vitro interaction via a consensus PCNA binding region | Q43690417 | ||
| Regulatory roles of p21 and apurinic/apyrimidinic endonuclease 1 in base excision repair | Q43771474 | ||
| Defective flap endonuclease 1 activity in mammalian cells is associated with impaired DNA repair and prolonged S phase delay | Q43785547 | ||
| Increased instability of intermediate alleles in families with sporadic Huntington disease compared to similar sized intermediate alleles in the general population | Q45291704 | ||
| Gender of the embryo contributes to CAG instability in transgenic mice containing a Huntington's disease gene | Q45301591 | ||
| Trinucleotide expansion in haploid germ cells by gap repair | Q45302664 | ||
| CTG repeats show bimodal amplification in E. coli | Q46115806 | ||
| Involvement of flap endonuclease 1 in base excision DNA repair. | Q48038198 | ||
| Structure, Recognition, and Processing of Cisplatin-DNA Adducts. | Q55035583 | ||
| The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin | Q64388522 | ||
| Multiple pathways of recombination define cellular responses to cisplatin | Q64388676 | ||
| A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair | Q64389285 | ||
| DNA structure determines protein binding and transcriptional efficiency of the proenkephalin cAMP-responsive enhancer | Q71585641 | ||
| Sensitivity of a S. cerevisiae RAD27 deletion mutant to DNA-damaging agents and in vivo complementation by the human FEN-1 gene | Q73135068 | ||
| Human MSH2 binds to trinucleotide repeat DNA structures associated with neurodegenerative diseases | Q73494415 | ||
| Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion | Q73626789 | ||
| Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation | Q73911234 | ||
| Expansion and length-dependent fragility of CTG repeats in yeast | Q74128701 | ||
| GAA instability in Friedreich's Ataxia shares a common, DNA-directed and intraallelic mechanism with other trinucleotide diseases | Q74771975 | ||
| P433 | issue | 17 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6063-6074 | |
| P577 | publication date | 2003-09-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability | |
| P478 | volume | 23 |
| Q34712058 | A 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β |
| Q37406053 | ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice |
| Q37584997 | Abnormal base excision repair at trinucleotide repeats associated with diseases: a tissue-selective mechanism |
| Q24816457 | Advances in mechanisms of genetic instability related to hereditary neurological diseases |
| Q37680431 | Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion |
| Q33637169 | Convergent transcription through a long CAG tract destabilizes repeats and induces apoptosis |
| Q37459997 | Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion. |
| Q38422476 | DNA Repair Endonucleases: Physiological Roles and Potential as Drug Targets. |
| Q35881868 | DNA base excision repair: a mechanism of trinucleotide repeat expansion. |
| Q34477635 | Defining Genetic Factors That Modulate Intergenerational CAG Repeat Instability inDrosophila melanogaster |
| Q33460873 | Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells |
| Q37687363 | Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes |
| Q36799848 | Evidence for base excision repair processing of DNA interstrand crosslinks |
| Q37048169 | Features of trinucleotide repeat instability in vivo |
| Q53599152 | Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1. |
| Q35865397 | Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner |
| Q35847997 | Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis |
| Q34343255 | Kinetics of endogenous mouse FEN1 in base excision repair. |
| Q35064141 | Microsatellite repeat instability and neurological disease |
| Q36741168 | Mitochondrial DNA damage and repair in neurodegenerative disorders |
| Q89721926 | On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability |
| Q34182956 | Potassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse model |
| Q27936102 | Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae |
| Q35680075 | Repeat instability during DNA repair: Insights from model systems |
| Q36277189 | Repeat instability: mechanisms of dynamic mutations |
| Q42177075 | Replication-dependent instability at (CTG)•(CAG) repeat hairpins in human cells |
| Q28386202 | Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis |
| Q39757351 | Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats. |
| Q37424442 | Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability |
| Q54481127 | Srs2 helicase of Saccharomyces cerevisiae selectively unwinds triplet repeat DNA. |
| Q30972892 | Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice |
| Q36466470 | The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder |
| Q35909014 | The Repeat Expansion Diseases: The dark side of DNA repair |
| Q38206321 | The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once |
| Q33917909 | Topoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction in human cells |
| Q36580985 | Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1. |
| Q38304778 | ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes |
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