| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.3109/10409239309086792 |
| P698 | PubMed publication ID | 8485987 |
| P2093 | author name string | Goodman MF | |
| Creighton S | |||
| Bloom LB | |||
| Petruska J | |||
| P2860 | cites work | Genetical Implications of the Structure of Deoxyribonucleic Acid | Q22122440 |
| Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR | Q24630526 | ||
| Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS) | Q24635921 | ||
| Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase | Q26778389 | ||
| Crystal structure and stability of a DNA duplex containing A(anti).G(syn) base-pairs | Q27727725 | ||
| Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations | Q27728602 | ||
| Refined crystal structure of an octanucleotide duplex with G . T mismatched base-pairs | Q27728951 | ||
| Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP | Q27728960 | ||
| Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia | Q27861076 | ||
| SOS Repair Hypothesis: Phenomenology of an Inducible DNA Repair Which is Accompanied by Mutagenesis | Q28141658 | ||
| The structure of DNA | Q28210412 | ||
| Regulation and expression of the adaptive response to alkylating agents | Q28289093 | ||
| Mutagenesis by apurinic/apyrimidinic sites | Q28300337 | ||
| MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis | Q28343030 | ||
| Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG | Q29616532 | ||
| The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) | Q29619959 | ||
| Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. | Q30400206 | ||
| Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions. A nuclear magnetic resonance study on an oligonucleotide containing a bromouracil-guanine base-pair as a function of pH. | Q30868730 | ||
| Analysis of the RNA- and DNA-dependent DNA polymerase activities of point mutants of HIV-1 reverse transcriptase lacking ribonuclease H activity | Q42616916 | ||
| O6-methylguanine and A.C and G.T mismatches cause asymmetric structural defects in DNA that are affected by DNA sequence | Q43620668 | ||
| A general structure for DNA-dependent DNA polymerases. | Q43654996 | ||
| Polymerase-specific differences in the DNA intermediates of frameshift mutagenesis. In vitro synthesis errors of Escherichia coli DNA polymerase I and its large fragment derivative | Q43974674 | ||
| Antimutagenic DNA polymerases of bacteriophage T4. | Q44086575 | ||
| Comparative efficiency of forming m4T.G versus m4T.A base pairs at a unique site by use of Escherichia coli DNA polymerase I (Klenow fragment) and Drosophila melanogaster polymerase alpha-primase complex | Q44210738 | ||
| Effect of pH on the base-mispairing properties of 5-bromouracil during DNA synthesis | Q44527969 | ||
| Detection of ras point mutations by polymerase chain reaction using mutation-specific, inosine-containing oligonucleotide primers | Q44701782 | ||
| Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases | Q44705872 | ||
| Studies on the biochemical basis of spontaneous mutation. III. Rate model for DNA polymerase-effected nucleotide misincorporation | Q44741297 | ||
| RecA protein and SOS. Correlation of mutagenesis phenotype with binding of mutant RecA proteins to duplex DNA and LexA cleavage | Q44834679 | ||
| Fidelity of the RNA-dependent DNA synthesis exhibited by the reverse transcriptases of human immunodeficiency virus types 1 and 2 and of murine leukemia virus: mispair extension frequencies | Q45872557 | ||
| Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural RNA | Q45873683 | ||
| Kinetics of extension of O6-methylguanine paired with cytosine or thymine in defined oligonucleotide sequences | Q46254218 | ||
| DNA replication fidelity: kinetics and thermodynamics | Q46859027 | ||
| Characterization of the high pH wobble structure of the 2-aminopurine.cytosine mismatch by N-15 NMR spectroscopy | Q47580781 | ||
| The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants | Q50192890 | ||
| Bacterial mutator genes and the control of spontaneous mutation | Q50228161 | ||
| Comparative rates of spontaneous mutation | Q50244165 | ||
| Kinetic mechanism of DNA polymerase I (Klenow). | Q52582535 | ||
| Fidelity of replication of bacteriophage X174 DNA in vitro and in Vivo | Q52873405 | ||
| Influence of local nucleotide sequence on substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro | Q52873585 | ||
| Nonrandom substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro. | Q52875047 | ||
| Thermodynamic comparison of the base pairs formed by the carcinogenic lesion O6-methylguanine with reference both to Watson-Crick pairs and to mismatched pairs. | Q53514339 | ||
| Genetic control of mutation rates in bacteriophageT4. | Q53766791 | ||
| The specific mutagenic effect of base analogues on Phage T4 | Q54094851 | ||
| Mutational specificity of a conditional Escherichia coli mutator, mutD5 | Q54154876 | ||
| In vitro evidence that UV-induced frameshift and substitution mutations at T tracts are the result of misalignment-mediated replication past a specific thymine dimer. | Q54680558 | ||
| The accuracy of reverse transcriptase from HIV-1. | Q54738770 | ||
| Oxidative damage in DNA. Lack of mutagenicity by thymine glycol lesions. | Q54748389 | ||
| Mechanism of mutagenesis by O6-methylguanine | Q59068375 | ||
| DNA repair enzymes | Q39532106 | ||
| DNA mismatch correction | Q39664959 | ||
| Inducible DNA repair systems | Q39826678 | ||
| Fidelity of DNA synthesis | Q40113209 | ||
| 2-Aminopurine | Q40281516 | ||
| The SOS regulatory system of Escherichia coli | Q40335741 | ||
| Synthesis and biophysical studies of short oligodeoxynucleotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynucleotide synthesis. | Q40461899 | ||
| Synthesis and physicochemical properties of two analogs of poly(dA): poly(2-aminopurine-9-β-D-deoxyribonucleotide) and poly 2-amino-deoxyadenylic acid | Q40465040 | ||
| Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural DNA. | Q40521759 | ||
| Complementary base pairing and the origin of substitution mutations | Q41060332 | ||
| Interaction of DNA with the Klenow fragment of DNA polymerase I studied by time-resolved fluorescence spectroscopy | Q33376429 | ||
| Direct electrophoretic detection of the allelic state of single DNA molecules in human sperm by using the polymerase chain reaction | Q33635397 | ||
| Comparison between DNA melting thermodynamics and DNA polymerase fidelity | Q33642760 | ||
| Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair | Q33663239 | ||
| Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vector | Q33663733 | ||
| A Factor (or Mutator Gene) Influencing Mutation Rates in Escherichia Coli | Q33714309 | ||
| Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia | Q33850554 | ||
| T5 DNA polymerase: structural--functional relationships to other DNA polymerases | Q33861715 | ||
| A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication | Q33865033 | ||
| Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation | Q34035189 | ||
| 8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity | Q34119141 | ||
| Structure of an adenine-cytosine base pair in DNA and its implications for mismatch repair | Q34196889 | ||
| Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday | Q34229913 | ||
| Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication | Q34257072 | ||
| Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used | Q34314972 | ||
| Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. | Q34315598 | ||
| Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs | Q34319463 | ||
| Bacteriophage PRD1 DNA polymerase: evolution of DNA polymerases | Q34369297 | ||
| Specificity and efficiency of editing of mismatches involved in the formation of base-substitution mutations by the 3'----5' exonuclease activity of phage T4 DNA polymerase | Q34595206 | ||
| Enzyme associations in T4 phage DNA precursor synthesis | Q35041189 | ||
| Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine | Q35047947 | ||
| 2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA | Q35059875 | ||
| Detection of single DNA base differences by competitive oligonucleotide priming | Q35222182 | ||
| Sites of termination of in vitro DNA synthesis on ultraviolet- and N-acetylaminofluorene-treated phi X174 templates by prokaryotic and eukaryotic DNA polymerases | Q35300157 | ||
| Structure and function of the bacteriophage T4 DNA polymerase holoenzyme | Q35359717 | ||
| On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro | Q35360018 | ||
| Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,T). | Q35556177 | ||
| Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro. | Q35564216 | ||
| Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity | Q35594093 | ||
| MutM, a protein that prevents G C→T A transversions, is formamidopyrimidine-DNA glycosylase | Q35770316 | ||
| Effects of primer-template mismatches on the polymerase chain reaction: human immunodeficiency virus type 1 model studies | Q35829749 | ||
| Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector | Q35837992 | ||
| Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR | Q35927120 | ||
| On the specificity of DNA polymerase | Q35970247 | ||
| The fidelity of base selection by the polymerase subunit of DNA polymerase III holoenzyme | Q36058122 | ||
| Mutagenic frequencies of site-specifically located O6-methylguanine in wild-type Escherichia coli and in a strain deficient in ada-methyltransferase | Q36129916 | ||
| SOS-dependent replication past a single trans-syn T-T cyclobutane dimer gives a different mutation spectrum and increased error rate compared with replication past this lesion in uninduced cells | Q36160219 | ||
| Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms | Q36317689 | ||
| Deoxyribonucleotide pools, base pairing, and sequence configuration affecting bromodeoxyuridine- and 2-aminopurine-induced mutagenesis | Q36362460 | ||
| Enzymatic synthesis of deoxyribonucleic acid. X. Influence of bromouracil substitutions on replication | Q36394308 | ||
| Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro | Q36765526 | ||
| Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA | Q37132610 | ||
| Escherichia coli MutY protein has both N-glycosylase and apurinic/apyrimidinic endonuclease activities on A.C and A.G mispairs | Q37209405 | ||
| Fidelity mechanisms in DNA replication | Q37285267 | ||
| Eukaryotic DNA polymerases | Q37285272 | ||
| Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III | Q37296938 | ||
| Detection of a guanine X adenine base pair in a decadeoxyribonucleotide by proton magnetic resonance spectroscopy | Q37341850 | ||
| The in vivo mutagenic frequency and specificity of O6-methylguanine in phi X174 replicative form DNA. | Q37401468 | ||
| Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis | Q37407082 | ||
| DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies | Q37442754 | ||
| uvrA and recA mutations inhibit a site-specific transition produced by a single O6-methylguanine in gene G of bacteriophage phi X174. | Q37536056 | ||
| Demonstration of the production of frameshift and base-substitution mutations by quasipalindromic DNA sequences | Q37566558 | ||
| In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome | Q37572277 | ||
| Infidelity of DNA synthesis associated with bypass of apurinic sites | Q37601868 | ||
| A fidelity assay using "dideoxy" DNA sequencing: a measurement of sequence dependence and frequency of forming 5-bromouracil X guanine base mispairs | Q37678883 | ||
| Mutagenic repair in Escherichia coli: products of the recA gene and of the umuD and umuC genes act at different steps in UV-induced mutagenesis | Q37692184 | ||
| The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions? | Q37713424 | ||
| Frameshift mutation: determinants of specificity | Q37794682 | ||
| Mutation induced by DNA damage: a many protein affair | Q37892175 | ||
| Minimal kinetic mechanism for misincorporation by DNA polymerase I (Klenow fragment) | Q38325804 | ||
| Reverse transcriptase from human immunodeficiency virus: a single template-primer binding site serves two physically separable catalytic functions | Q38332456 | ||
| An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics | Q38337035 | ||
| Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant | Q38337038 | ||
| cis-syn thymine dimers are not absolute blocks to replication by DNA polymerase I of Escherichia coli in vitro. | Q38342006 | ||
| Fluorescent oligonucleotides and deoxynucleotide triphosphates: preparation and their interaction with the large (Klenow) fragment of Escherichia coli DNA polymerase I. | Q38344586 | ||
| DNA substrate structural requirements for the exonuclease and polymerase activities of procaryotic and phage DNA polymerases | Q38345051 | ||
| Stepwise mechanism of HIV reverse transcriptase: primer function of phosphorothioate oligodeoxynucleotide | Q38345288 | ||
| Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity | Q38346541 | ||
| Mismatch repair in Escherichia coli | Q39480893 | ||
| P433 | issue | 2 | |
| P304 | page(s) | 83-126 | |
| P577 | publication date | 1993-01-01 | |
| P1433 | published in | Critical Reviews in Biochemistry and Molecular Biology | Q5186661 |
| P1476 | title | Biochemical basis of DNA replication fidelity | |
| P478 | volume | 28 |
| Q34329434 | 1H NMR determination of base-pair lifetimes in oligonucleotides containing single base mismatches |
| Q40392746 | 3'-5' proofreading-induced detection of point mutations by PCR using Tli DNA polymerase |
| Q54630951 | 3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase. |
| Q40240453 | 8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, 'action-at-a-distance' mutagenesis and inhibition of replication |
| Q36768809 | A general strategy for expanding polymerase function by droplet microfluidics |
| Q41973778 | A mechanism of nucleotide misincorporation during transcription due to template-strand misalignment |
| Q39516070 | A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis |
| Q34604079 | A new look at old mutants of T4 DNA polymerase |
| Q59049012 | A specific partner for abasic damage in DNA |
| Q36588022 | A thymidine triphosphate shape analog lacking Watson-Crick pairing ability is replicated with high sequence selectivity |
| Q43981486 | A unique unnatural base pair between a C analogue, pseudoisocytosine, and an A analogue, 6-methoxypurine, in replication |
| Q40463112 | ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts |
| Q27323759 | Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1 |
| Q44525342 | Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts |
| Q37097247 | Accuracy of lesion bypass by yeast and human DNA polymerase eta. |
| Q36177279 | Accurate and efficient bypass of 8,5'-cyclopurine-2'-deoxynucleosides by human and yeast DNA polymerase η. |
| Q39458346 | Acidic residues critical for the activity and biological function of yeast DNA polymerase eta. |
| Q28247869 | Activities and mechanism of DNA polymerase beta |
| Q41859576 | Alkylating agents induce UVM, a recA-independent inducible mutagenic phenomenon in Escherichia coli |
| Q39892134 | Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment. |
| Q39728310 | An in vitro screening technique for DNA polymerases that can incorporate modified nucleotides. Pseudo-thymidine as a substrate for thermostable polymerases |
| Q30047870 | An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules |
| Q29395124 | An unnatural hydrophobic base pair system: site-specific incorporation of nucleotide analogs into DNA and RNA |
| Q38344371 | Analysis of the effect of bulk at N2-alkylguanine DNA adducts on catalytic efficiency and fidelity of the processive DNA polymerases bacteriophage T7 exonuclease- and HIV-1 reverse transcriptase |
| Q50913062 | Analyzing the Catalytic Activities and Interactions of Eukaryotic Translesion Synthesis Polymerases. |
| Q27024636 | Antimutator variants of DNA polymerases |
| Q39229297 | Arg660Ser mutation in Thermus aquaticus DNA polymerase I suppresses T-->C transitions: implication of wobble base pair formation at the nucleotide incorporation step |
| Q36220380 | Both DNA strands of antibody genes are hypermutation targets |
| Q47119488 | Calcium-driven DNA synthesis by a high-fidelity DNA polymerase |
| Q44987429 | Chain termination and inhibition of Saccharomyces cerevisiae poly(A) polymerase by C-8-modified ATP analogs |
| Q37326085 | Competitive repair pathways in immunoglobulin gene hypermutation. |
| Q45672901 | Contribution of the 3'- to 5'-exonuclease activity of herpes simplex virus type 1 DNA polymerase to the fidelity of DNA synthesis |
| Q37543875 | Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site |
| Q37695534 | DNA interstrand cross-linking upon irradiation of aryl halide C-nucleotides |
| Q40565074 | DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA. |
| Q34042552 | DNA polymerase beta ribonucleotide discrimination: insertion, misinsertion, extension, and coding. |
| Q42953629 | DNA polymerase beta: analysis of the contributions of tyrosine-271 and asparagine-279 to substrate specificity and fidelity of DNA replication by pre-steady-state kinetics |
| Q36677703 | DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG. |
| Q30492695 | DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kinetics |
| Q34603989 | DNA polymerase fidelity: from genetics toward a biochemical understanding |
| Q43518631 | DNA polymerase mutagenic bypass and proofreading of endogenous DNA lesions. |
| Q42117840 | DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase |
| Q26822699 | DNA polymerase ε and its roles in genome stability |
| Q35978843 | DNA polymerases eta and iota |
| Q35677447 | DNA replication fidelity |
| Q28295863 | DNA replication fidelity and cancer |
| Q24548004 | DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiae |
| Q33938993 | DNA synthesis fidelity by the reverse transcriptase of the yeast retrotransposon Ty1. |
| Q48276998 | Design and Discovery of New Combinations of Mutant DNA Polymerases and Modified DNA Substrates. |
| Q34078211 | Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication |
| Q34008591 | Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation |
| Q30897941 | Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha |
| Q27694673 | Double GC:GC mismatch in dsDNA enhances local dynamics retaining the DNA footprint: a high-resolution NMR study |
| Q42548215 | Dysfunctional proofreading in the Escherichia coli DNA polymerase III core |
| Q37626119 | Effect of dNTP pool alterations on fidelity of leading and lagging strand DNA replication in E. coli. |
| Q44641231 | Effect of the Oxidized Guanosine Lesions Spiroiminodihydantoin and Guanidinohydantoin on Proofreading by Escherichia coli DNA Polymerase I (Klenow Fragment) in Different Sequence Contexts |
| Q33814887 | Effects of exonuclease activity and nucleotide selectivity of the herpes simplex virus DNA polymerase on the fidelity of DNA replication in vivo. |
| Q36948837 | Effects of the N terminus of mouse DNA polymerase κ on the bypass of a guanine-benzo[a]pyrenyl adduct |
| Q43816434 | Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts |
| Q38362195 | Efficiency of correct nucleotide insertion governs DNA polymerase fidelity. |
| Q27934276 | Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase eta. |
| Q77530267 | Efficient replication between non-hydrogen-bonded nucleoside shape analogs |
| Q79266795 | Elements for a theory of molecular evolution |
| Q34342518 | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase |
| Q29619958 | Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions |
| Q73348907 | Evaluating the Effects of Enhanced Processivity and Metal Ions on Translesion DNA Replication Catalyzed by the Bacteriophage T4 DNA Polymerase |
| Q51689692 | Exonuclease activity of proofreading DNA polymerases is at the origin of artifacts in molecular profiling studies. |
| Q39733616 | Exonuclease-deficient polymerase mutant of herpes simplex virus type 1 induces altered spectra of mutations |
| Q36627376 | Exploring the role of large conformational changes in the fidelity of DNA polymerase beta |
| Q38356442 | Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct |
| Q43734029 | Fidelity and damage bypass ability of Schizosaccharomyces pombe Eso1 protein, comprised of DNA polymerase eta and sister chromatid cohesion protein Ctf7. |
| Q27931739 | Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta. |
| Q56637826 | Fidelity of DNA replication—a matter of proofreading |
| Q46320742 | Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies |
| Q44049947 | Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment |
| Q38313569 | Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe |
| Q37454368 | Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation |
| Q38318428 | Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: probing T7 DNA polymerase with variably sized base pairs |
| Q46607481 | Gel kinetic analysis of DNA polymerase fidelity in the presence of proofreading using bacteriophage T4 DNA polymerase |
| Q35869250 | Genetic Bit Analysis: a solid phase method for typing single nucleotide polymorphisms |
| Q36670381 | Genetic elements of plant viruses as tools for genetic engineering |
| Q36530952 | Genetic fidelity under harsh conditions: analysis of spontaneous mutation in the thermoacidophilic archaeon Sulfolobus acidocaldarius |
| Q34439328 | Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. |
| Q39903099 | High density labeling of polymerase chain reaction products with the fluorescent base analogue tCo |
| Q34957121 | High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds. |
| Q34157412 | Highly Precise Shape Mimicry by a Difluorotoluene Deoxynucleoside, a Replication‐Competent Substitute for Thymidine |
| Q38354607 | Highly efficient incorporation of the fluorescent nucleotide analogs tC and tCO by Klenow fragment |
| Q24534772 | Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini |
| Q33268518 | Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity |
| Q91664398 | Human DNA polymerase delta requires an iron-sulfur cluster for high-fidelity DNA synthesis |
| Q34141563 | Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides |
| Q24670499 | Human DNA polymerase kappa uses template-primer misalignment as a novel means for extending mispaired termini and for generating single-base deletions |
| Q36466634 | Human DNA polymerase ε is able to efficiently extend from multiple consecutive ribonucleotides |
| Q24803070 | Hybridization properties and enzymatic replication of oligonucleotides containing the photocleavable 7-nitroindole base analog |
| Q37528573 | Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA. |
| Q36002542 | Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathways |
| Q37161426 | Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase. |
| Q40209793 | Iminodiacetic-phosphoramidates as metabolic prototypes for diversifying nucleic acid polymerization in vivo |
| Q54578229 | Iminodipropionic acid as the leaving group for DNA polymerization by HIV-1 reverse transcriptase. |
| Q58048567 | Impact of DNA physical properties on local sequence bias of human mutation |
| Q35569252 | Importance of steric effects on the efficiency and fidelity of transcription by T7 RNA polymerase |
| Q39898806 | In Vitro Lesion Bypass Studies of O(4)-Alkylthymidines with Human DNA Polymerase η. |
| Q36742594 | In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase |
| Q37395678 | In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosine |
| Q35893844 | In vitro replication and thermodynamic studies of methylation and oxidation modifications of 6-thioguanine |
| Q35189851 | In vitro replication studies of carboxymethylated DNA lesions with Saccharomyces cerevisiae polymerase η. |
| Q40675013 | Increased G-->A transition frequencies displayed by primer grip mutants of human immunodeficiency virus type 1 reverse transcriptase |
| Q48043477 | Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA. |
| Q31655742 | Inefficient bypass of an abasic site by DNA polymerase eta. |
| Q53639781 | Influence of DNA structure on DNA polymerase beta active site function: extension of mutagenic DNA intermediates. |
| Q78068262 | Inhibition of Escherichia coli DNA polymerase-I by the anti-cancer drug cis-diaminedichloroplatinum(II): what roles do polymerases play in cis-platin-induced cytotoxicity? |
| Q31777720 | Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69. |
| Q27935721 | Interaction with PCNA is essential for yeast DNA polymerase eta function |
| Q33692254 | Involvement of gene products in bacterial evolution |
| Q73053417 | Isotopic assays of viral polymerases and related proteins |
| Q37296730 | Kinetic analysis of an efficient DNA-dependent TNA polymerase |
| Q37540918 | Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2'-deoxyguanosine by the catalytic core of yeast DNA polymerase η. |
| Q38289676 | Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1. |
| Q38315115 | Kinetic evidence for inefficient and error-prone bypass across bulky N2-guanine DNA adducts by human DNA polymerase iota |
| Q44007612 | Kinetics of deoxyribonucleotide insertion and extension at abasic template lesions in different sequence contexts using HIV-1 reverse transcriptase |
| Q45144504 | Kinetics of nucleotide incorporation opposite DNA bulky guanine N2 adducts by processive bacteriophage T7 DNA polymerase (exonuclease-) and HIV-1 reverse transcriptase |
| Q22121984 | Lesion (in)tolerance reveals insights into DNA replication fidelity |
| Q54446661 | Lesion bypass activity of DNA polymerase A from the extremely radioresistant organism Deinococcus radiodurans. |
| Q38363801 | Local deformations revealed by dynamics simulations of DNA polymerase Beta with DNA mismatches at the primer terminus |
| Q41159214 | Mass-spectrometry analysis of modifications at DNA termini induced by DNA polymerases |
| Q28597450 | Methylated Cytosines Mutate to Transcription Factor Binding Sites that Drive Tetrapod Evolution |
| Q34129209 | Minor Groove Interactions between Polymerase and DNA: More Essential to Replication than Watson−Crick Hydrogen Bonds? |
| Q27643487 | Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta |
| Q34725650 | Molecular basis of fidelity of DNA synthesis and nucleotide specificity of retroviral reverse transcriptases |
| Q41770330 | Multiple forms of DNA polymerase from the thermo-acidophilic eubacterium Bacillus acidocaldarius: purification, biochemical characterization and possible biological role |
| Q35842713 | Multiple solutions to inefficient lesion bypass by T7 DNA polymerase. |
| Q37698525 | Multiplex genotype determination at a large number of gene loci |
| Q36555081 | Mutation avoidance and DNA repair proficiency in Ustilago maydis are differentially lost with progressive truncation of the REC1 gene product |
| Q39686714 | Mutation spectra of herpes simplex virus type 1 thymidine kinase mutants |
| Q73019259 | Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity |
| Q34055320 | Mutator suppression and escape from replication error-induced extinction in yeast |
| Q55383095 | N6-Methyladenine hinders RNA- and DNA-directed DNA synthesis: application in human rRNA methylation analysis of clinical specimens. |
| Q38361820 | Neighbouring bases in template influence base-pairing of isoguanine |
| Q43603086 | O-helix mutant T664P of Thermus aquaticus DNA polymerase I: altered catalytic properties for incorporation of incorrect nucleotides but not correct nucleotides |
| Q38323024 | O4-alkyl-2'-deoxythymidine cross-linked DNA to probe recognition and repair by O6-alkylguanine DNA alkyltransferases |
| Q45072743 | Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase. |
| Q24548129 | PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases |
| Q37011650 | Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity |
| Q24548300 | Physical and functional interactions of human DNA polymerase eta with PCNA |
| Q49948938 | Physico-chemical profiles of the wobble ↔ Watson-Crick G*·2AP(w) ↔ G·2AP(WC) and A·2AP(w) ↔ A*·2AP(WC) tautomerisations: a QM/QTAIM comprehensive survey. |
| Q35212044 | Prechemistry versus preorganization in DNA replication fidelity |
| Q34115892 | Probing the active site tightness of DNA polymerase in subangstrom increments |
| Q56903200 | Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase delta |
| Q35868344 | Proofreading DNA: recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I |
| Q33598642 | RB69 DNA polymerase structure, kinetics, and fidelity |
| Q34480916 | Radiosensitization by a modified nucleotide that produces DNA interstrand cross-links under hypoxic conditions |
| Q54647452 | Rapid and sensitive detection of DNA polymerase fidelity by singly labeled smart fluorescent probes |
| Q35905947 | Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. |
| Q36681696 | Refined solution structure of a DNA heteroduplex containing an aldehydic abasic site |
| Q39114338 | Replication across O6-methylguanine by human DNA polymerase beta in vitro. Insights into the futile cytotoxic repair and mutagenesis of O6-methylguanine |
| Q39683254 | Replication fidelity of the supF gene integrated in the thymidine kinase locus of herpes simplex virus type 1. |
| Q73555611 | Replication of template-primers containing propanodeoxyguanosine by DNA polymerase beta. Induction of base pair substitution and frameshift mutations by template slippage and deoxynucleoside triphosphate stabilization |
| Q27930712 | Replication past O(6)-methylguanine by yeast and human DNA polymerase eta. |
| Q38847971 | Replicative Bypass Studies of α-Anomeric Lesions of 2'-Deoxyribonucleosides in Vitro |
| Q39407326 | Replicative Bypass of O(2)-Alkylthymidine Lesions in Vitro |
| Q34348711 | Reversal of a mutator activity by a nearby fidelity-neutral substitution in the RB69 DNA polymerase binding pocket |
| Q27939380 | Role of DNA polymerase eta in the bypass of a (6-4) TT photoproduct |
| Q24541478 | Role of human DNA polymerase kappa as an extender in translesion synthesis |
| Q28363488 | Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites |
| Q42687325 | Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol beta |
| Q57050038 | Snapshots of a modified nucleotide moving through the confines of a DNA polymerase |
| Q50134974 | Sources of spontaneous mutagenesis in bacteria. |
| Q37371343 | Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases |
| Q24537135 | Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA. |
| Q27677038 | Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue |
| Q34315115 | Structure and replication of yDNA: a novel genetic set widened by benzo-homologation |
| Q45153419 | Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication |
| Q39720937 | Structure of the hydrogen bonding complex of O6-methylguanine with cytosine and thymine during DNA replication |
| Q27656089 | Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXES |
| Q27758682 | Structures of apurinic and apyrimidinic sites in duplex DNAs |
| Q28251979 | Structures of mismatch replication errors observed in a DNA polymerase |
| Q43087758 | Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase zeta |
| Q39446100 | Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators |
| Q57895656 | Synthesis of 3-(2-deoxy-β-d-ribofuranosyl)pyridin-2-one and 2-amino-6-(N,N-dimethylamino)-9-(2-deoxy-β-d-ribofuranosyl)purine derivatives for an unnatural base pair |
| Q39256550 | Synthesis, and in vitro enzymatic and antiviral evaluation of d4T polyphosphate derivatives as chain terminators |
| Q41174277 | Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides |
| Q39117143 | Systematic characterization of 2'-deoxynucleoside- 5'-triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNA |
| Q44531735 | TNA synthesis by DNA polymerases |
| Q30769976 | Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. |
| Q28251730 | Terminal deoxynucleotidyl transferase: the story of a misguided DNA polymerase |
| Q38341988 | The 5'-exonuclease activity of bacteriophage T4 RNase H is stimulated by the T4 gene 32 single-stranded DNA-binding protein, but its flap endonuclease is inhibited |
| Q38356754 | The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase alpha is important in discriminating correct deoxyribonucleotides from incorrect ones |
| Q36026062 | The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination |
| Q40533640 | The control of the discrimination between dNTP and rNTP in DNA and RNA polymerase |
| Q24804691 | The effect of the 2-amino group of 7,8-dihydro-8-oxo-2'-deoxyguanosine on translesion synthesis and duplex stability |
| Q34780836 | The effects of the ring fragmentation product of thymidine C5-hydrate on phosphodiesterases and klenow (exo-) fragment |
| Q40085607 | The energetic difference between synthesis of correct and incorrect base pairs accounts for highly accurate DNA replication |
| Q24630867 | The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases |
| Q38158093 | The high cost of fidelity |
| Q24683573 | The human DINB1 gene encodes the DNA polymerase Poltheta |
| Q77892158 | The mechanism of action of T7 DNA polymerase |
| Q38333960 | The proofreading pathway of bacteriophage T4 DNA polymerase. |
| Q34570808 | The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer |
| Q27640849 | The structural basis for the mutagenicity of O6-methyl-guanine lesions |
| Q40176435 | The structural impact of DNA mismatches |
| Q24817153 | The use of thymidine analogs to improve the replication of an extra DNA base pair: a synthetic biological system |
| Q54477526 | Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug. |
| Q39724036 | Thermodynamics of internal C.T mismatches in DNA. |
| Q74036849 | Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix |
| Q48032922 | Transcriptional fidelity and proofreading by RNA polymerase II. |
| Q43619478 | Translesion DNA synthesis catalyzed by human pol eta and pol kappa across 1,N6-ethenodeoxyadenosine. |
| Q38312615 | Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa |
| Q37213767 | Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ. |
| Q39095399 | Translesional synthesis on DNA templates containing the 2'-deoxyribonolactone lesion. |
| Q37412973 | Two Distinct Pathways Support Gene Correction by Single-Stranded Donors at DNA Nicks |
| Q33617135 | Universal bases for hybridization, replication and chain termination |
| Q36174707 | Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma |
| Q62590161 | Using 2-Aminopurine Fluorescence and Mutational Analysis to Demonstrate an Active Role of Bacteriophage T4 DNA Polymerase in Strand Separation Required for 3′ → 5′-Exonuclease Activity |
| Q38363604 | Using 2-aminopurine fluorescence to measure incorporation of incorrect nucleotides by wild type and mutant bacteriophage T4 DNA polymerases |
| Q41496563 | Variants of sequence family B Thermococcus kodakaraensis DNA polymerase with increased mismatch extension selectivity |
| Q34157423 | Varied Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes |
| Q27653071 | Versatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine Adducts |
| Q77520952 | Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions |
| Q38073986 | Why nature really chose phosphate |
| Q34473133 | Yeast DNA polymerase zeta is an efficient extender of primer ends opposite from 7,8-dihydro-8-Oxoguanine and O6-methylguanine |
| Q41652726 | Yeast DNA polymerase ϵ catalytic core and holoenzyme have comparable catalytic rates |
| Q38291977 | Yeast Rev1 protein is a G template-specific DNA polymerase |
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