Mutator phenotype induced by aberrant replication

scientific article published on February 1999

Mutator phenotype induced by aberrant replication is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.19.2.1126
P932PMC publication ID116042
P698PubMed publication ID9891047
P5875ResearchGate publication ID13398162

P2093author name stringT S Wang
D Bhaumik
V F Liu
P2860cites workStructural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damageQ24312006
Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitroQ24319018
The characterization of a mammalian DNA structure-specific endonucleaseQ24336672
S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombeQ24607761
Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathwayQ27938580
Biochemistry and genetics of eukaryotic mismatch repairQ28282377
Enzymes and reactions at the eukaryotic DNA replication forkQ28610363
Molecular genetic analysis of fission yeast Schizosaccharomyces pombeQ29547703
The structure and evolution of the human beta-globin gene familyQ29618222
A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replicationQ29618307
Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinasesQ32028781
Spectrum of spontaneous mutation at the APRT locus of Chinese hamster ovary cells: an analysis at the DNA sequence levelQ33574499
Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).Q33786528
Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion terminiQ33879867
Short, direct repeats at the breakpoints of deletions of the retinoblastoma geneQ34286847
Replication checkpoint enforced by kinases Cds1 and Chk1.Q34466698
Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombeQ34467598
Fission yeast with DNA polymerase delta temperature-sensitive alleles exhibits cell division cycle phenotypeQ34995794
Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes.Q36555338
Mutational effect of fission yeast polalpha on cell cycle eventsQ36897524
Base substitutions, frameshifts, and small deletions constitute ionizing radiation-induced point mutations in mammalian cellsQ37480732
Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genesQ37599112
Mutator phenotype may be required for multistage carcinogenesisQ37732904
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeastQ40365871
Hereditary Nonpolyposis Colorectal Cancer: the Syndrome, the Genes, and Historical PerspectivesQ40482404
Microsatellite instability: marker of a mutator phenotype in cancer.Q40630726
Gene deletions causing human genetic disease: mechanisms of mutagenesis and the role of the local DNA sequence environmentQ41182021
The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repairQ41396267
Cancer cells exhibit a mutator phenotypeQ41617067
rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrestQ42124885
Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repairQ46348708
A kinase from fission yeast responsible for blocking mitosis in S phaseQ48074342
The human gene mutation databaseQ57263881
Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombeQ57270224
Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1Q59061022
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repairQ64389285
DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeastQ70826114
The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phaseQ71733813
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
P304page(s)1126-1135
P577publication date1999-02-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleMutator phenotype induced by aberrant replication
P478volume19

Reverse relations

cites work (P2860)
Q37574087A coordinated temporal interplay of nucleosome reorganization factor, sister chromatin cohesion factor, and DNA polymerase alpha facilitates DNA replication
Q24643321Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation
Q33966167Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation
Q35963618Checkpoint activation regulates mutagenic translesion synthesis
Q28211143DNA mismatch repair and mutation avoidance pathways
Q30897941Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha
Q33853216Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage
Q33558478Fission yeast Rad17 associates with chromatin in response to aberrant genomic structures
Q37709083Genetics of lagging strand DNA synthesis and maturation in fission yeast: suppression analysis links the Dna2-Cdc24 complex to DNA polymerase delta
Q34618433Genomic Instability Induced by Mutations in Saccharomyces cerevisiae POL1
Q39572388In vitro expansion of mammalian telomere repeats by DNA polymerase alpha-primase
Q39455847Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta
Q46445542Methods for studying mutagenesis and checkpoints in Schizosaccharomyces pombe
Q37483304Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools
Q33786781Mutational spectrum analysis of RNase H(35) deficient Saccharomyces cerevisiae using fluorescence-based directed termination PCR.
Q44246963Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta
Q37011650Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity
Q60955060Regulation of Structure-Specific Endonucleases in Replication Stress
Q42051868Relationship of an hRAD54 gene polymorphism (2290 C/T) in an Ecuadorian population with chronic myelogenous leukemia.
Q33751481Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress
Q34930176Replication proteins influence the maintenance of telomere length and telomerase protein stability
Q34671481Role of fission yeast primase catalytic subunit in the replication checkpoint
Q39449001Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair
Q39459799Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control
Q38751802The repeatability of genome-wide mutation rate and spectrum estimates
Q42467404The role of DNA polymerase alpha in the control of mutagenesis in Saccharomyces cerevisiae cells starved for nutrients

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