DNA mismatch repair and mutation avoidance pathways

scientific article (publication date: April 2002)

DNA mismatch repair and mutation avoidance pathways is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/JCP.10077
P698PubMed publication ID11920679
P5875ResearchGate publication ID11443895

P50authorOliver FleckQ57647551
Christophe KunzQ59168322
P2093author name stringThomas M Marti
P2860cites workInteractions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancerQ22003969
MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1Q22009114
Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidanceQ22009967
MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instabilityQ22010995
Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexesQ24290314
The interaction of DNA mismatch repair proteins with human exonuclease IQ24291370
Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair proteinQ24309547
DNA polymerase delta is required for human mismatch repair in vitroQ24313002
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2Q24314329
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repairQ24318892
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6Q24323176
Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).Q24532243
The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2Q24596494
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication fociQ24602221
Mismatch repair deficiency associated with overexpression of the MSH3 geneQ24681589
Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repairQ27617873
Crystal structures of mismatch repair protein MutS and its complex with a substrate DNAQ27627633
The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatchQ27627644
Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repairQ27629464
Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.Q27929951
The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairsQ27930815
Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition.Q27932001
Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repairQ27932017
Enhancement of MSH2-MSH3-mediated mismatch recognition by the yeast MLH1-PMS1 complexQ27932428
Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeastQ27934236
A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognitionQ27934451
Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genesQ27934736
Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3.Q27934985
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutationsQ27935158
MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clampQ27935260
exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repairQ27935389
Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repairQ27938608
ATP-dependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexesQ27939412
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correctionQ27939611
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesisQ27939891
hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNAQ28138775
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complexQ28142999
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sitesQ28145111
The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switchQ28258968
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor CellsQ28292781
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cellsQ28292790
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologsQ34554581
Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutantsQ35063842
Evidence for short-patch mismatch repair in Saccharomyces cerevisiaeQ35115265
Mutator phenotypes in human colorectal carcinoma cell linesQ35568305
Repair of heteroduplex DNA molecules with multibase loops in Escherichia coliQ36102308
Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB.Q36182527
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repairQ36235057
Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sitesQ36272166
Mismatch repair, gene conversion, and crossing-over in two recombination-defective mutants of Drosophila melanogasterQ36314345
Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutationsQ36570003
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Mechanisms and biological effects of mismatch repairQ37041860
Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiaeQ37149138
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosisQ38293261
Escherichia coli MutL loads DNA helicase II onto DNA.Q38308417
Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA.Q38320783
hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalphaQ38336441
Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplexQ38337751
Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosisQ38344945
Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded proteinQ38346658
Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repairQ39449001
hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairsQ28343394
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repairQ28508905
HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functionsQ28589491
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repairQ28610848
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repairQ28610858
Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalphaQ28610863
Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanismQ28610864
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repairQ29615027
Mismatch repair in replication fidelity, genetic recombination, and cancer biologyQ29616483
Binding and repair of mismatched DNA mediated by Rhp14, the fission yeast homologue of human XPA.Q30993003
The swi4+ gene of Schizosaccharomyces pombe encodes a homologue of mismatch repair enzymesQ31160628
Evidence for a physical interaction between the Escherichia coli methyl-directed mismatch repair proteins MutL and UvrD.Q32108861
Nucleotide excision repair: from E. coli to man.Q33601014
Identification of proteins of Escherichia coli and Saccharomyces cerevisiae that specifically bind to C/C mismatches in DNA.Q33617930
Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correctionQ33680797
Mouse models for colorectal cancerQ33739279
DNA mismatch repair catalyzed by extracts of mitotic, postmitotic, and senescent Drosophila tissues and involvement of mei-9 gene function for full activityQ33772428
Sliding clamps: a (tail)ored fit.Q33830292
Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coliQ33849909
Mismatch repair defects in cancerQ33885063
MutS mediates heteroduplex loop formation by a translocation mechanismQ33887145
Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleasesQ33888460
Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiaeQ33933718
Human DNA mismatch repair in vitro operates independently of methylation status at CpG sitesQ33939108
Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancersQ33943737
Efficient repair of large DNA loops in Saccharomyces cerevisiaeQ33948391
The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization.Q33957081
Base excision repair of DNA in mammalian cellsQ33957142
The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiaeQ33957467
Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavageQ33968982
DNA mismatch repair and genetic instabilityQ34090778
A role for MLH3 in hereditary nonpolyposis colorectal cancerQ34093711
Role of MED1 (MBD4) Gene in DNA repair and human cancerQ34194512
Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I.Q34311670
Evolutionary origin, diversification and specialization of eukaryotic MutS homolog mismatch repair proteinsQ39542069
Mutator phenotype induced by aberrant replicationQ39610863
Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genesQ40022200
Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.Q40920177
The human PMS2L proteins do not interact with hMLH1, a major DNA mismatch repair proteinQ40963280
Repair of large insertion/deletion heterologies in human nuclear extracts is directed by a 5' single-strand break and is independent of the mismatch repair systemQ40969083
Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A.Q40990759
The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repairQ41396267
Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.Q41676798
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancerQ42856984
Role of the DNA repair nucleases Rad13, Rad2 and Uve1 of Schizosaccharomyces pombe in mismatch correction.Q43860202
Kinetic measurement of the step size of DNA unwinding by Escherichia coli UvrD helicaseQ47315601
Mismatch repair, molecular switches, and signal transductionQ47787090
Frameshift mismatch recognition by the human MutS alpha complexQ47791002
Exonuclease X of Escherichia coli. A novel 3'-5' DNase and Dnaq superfamily member involved in DNA repair.Q47922901
Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repairQ47979502
The high mobility group domain protein Cmb1 of Schizosaccharomyces pombe binds to cytosines in base mismatches and opposite chemically altered guaninesQ48010364
Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correctionQ48076989
Mismatch recognition and DNA-dependent stimulation of the ATPase activity of hMutSalpha is abolished by a single mutation in the hMSH6 subunitQ50335571
Cleavage of substrates with mismatched nucleotides by Flap endonuclease-1. Implications for mammalian Okazaki fragment processing.Q52535059
A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.Q53963518
Photocross-linking of the NH2-terminal region of Taq MutS protein to the major groove of a heteroduplex DNA.Q54558924
Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteinsQ59040284
The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonucleaseQ59087847
Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1Q59168212
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectDNA mismatch repairQ2984243
P304page(s)28-41
P577publication date2002-04-01
P1433published inJournal of Cellular PhysiologyQ1524270
P1476titleDNA mismatch repair and mutation avoidance pathways
P478volume191

Reverse relations

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