review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1050284220 |
P356 | DOI | 10.1038/SJ.ONC.1203036 |
P698 | PubMed publication ID | 10498885 |
P5875 | ResearchGate publication ID | 12801246 |
P2093 | author name string | Yang K | |
Edelmann W | |||
Kucherlapati R | |||
Lipkin M | |||
Heyer J | |||
P2860 | cites work | Identification of deletion mutations and three new genes at the familial polyposis locus | Q24294229 |
Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
Homeosis and intestinal tumours in Cdx2 mutant mice | Q24323758 | ||
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse | Q34344768 | ||
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs | Q34554581 | ||
Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice | Q36084832 | ||
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene | Q36643609 | ||
Parallel human genome analysis: microarray-based expression monitoring of 1000 genes | Q36825305 | ||
Mechanisms and biological effects of mismatch repair | Q37041860 | ||
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis | Q38293261 | ||
Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene | Q40951183 | ||
Familial risk and colorectal cancer | Q41264786 | ||
DNA loop repair by human cell extracts | Q41429743 | ||
The role of beta-catenin in cell adhesion, signal transduction, and cancer. | Q41702467 | ||
Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas | Q42013009 | ||
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast | Q42427955 | ||
Mutations in the SMAD4/DPC4 gene in juvenile polyposis | Q45345229 | ||
CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer | Q47684602 | ||
PTEN and inherited hamartoma-cancer syndromes | Q47852476 | ||
Retinal pigment epithelium abnormalities in mice with adenomatous polyposis coli gene disruption. | Q52525509 | ||
Suppression of intestinal polyp development by low-fat and high-fiber diet in Apc(delta716) knockout mice. | Q53439555 | ||
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. | Q54558350 | ||
Suppression of intestinal neoplasia by DNA hypomethylation. | Q54613769 | ||
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene | Q24562061 | ||
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors | Q24564011 | ||
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | Q27860717 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis | Q27939891 | ||
Lessons from hereditary colorectal cancer | Q28131788 | ||
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene | Q28236533 | ||
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer | Q28253384 | ||
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer | Q28256988 | ||
Association of the APC tumor suppressor protein with catenins | Q28257313 | ||
Biochemistry and genetics of eukaryotic mismatch repair | Q28282377 | ||
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over | Q28282791 | ||
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells | Q28292781 | ||
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer | Q28294774 | ||
Mammalian MutS homologue 5 is required for chromosome pairing in meiosis | Q28295022 | ||
Identification of FAP locus genes from chromosome 5q21 | Q28300247 | ||
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes | Q28508338 | ||
MSH2 deficient mice are viable and susceptible to lymphoid tumours | Q28508486 | ||
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair | Q28508905 | ||
Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts | Q28510629 | ||
Meiotic pachytene arrest in MLH1-deficient mice | Q28510650 | ||
Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development | Q28511030 | ||
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo | Q28512702 | ||
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility | Q28592583 | ||
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma | Q29615026 | ||
Mismatch repair in replication fidelity, genetic recombination, and cancer biology | Q29616483 | ||
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene | Q29616490 | ||
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1 | Q29616726 | ||
Gene expression profiles in normal and cancer cells | Q29619943 | ||
Identification and characterization of the familial adenomatous polyposis coli gene | Q29620382 | ||
The oncogenic activation of beta-catenin | Q33540073 | ||
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia | Q34313013 | ||
P433 | issue | 38 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | colorectal cancer | Q188874 |
colorectal carcinoma | Q25493920 | ||
P304 | page(s) | 5325-5333 | |
P577 | publication date | 1999-09-01 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Mouse models for colorectal cancer | |
P478 | volume | 18 |
Q28272700 | A panoply of errors: polymerase proofreading domain mutations in cancer |
Q28744112 | Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium |
Q61415596 | B-mode compound imaging in mice |
Q74148150 | Beta-catenin and adenomatous polyposis coli (APC) mutations in adenomas from hereditary non-polyposis colorectal cancer patients |
Q24302011 | Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA |
Q58737393 | Colorectal carcinogenesis: Insights into the cell death and signal transduction pathways: A review |
Q36412661 | Cryptosporidium parvum, a potential cause of colic adenocarcinoma |
Q53388373 | Cyclooxygenase-2 expression in spontaneous intestinal neoplasia of domestic dogs. |
Q28211143 | DNA mismatch repair and mutation avoidance pathways |
Q35788926 | DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice |
Q33852849 | Detecting low penetrance genes in cancer: the way ahead |
Q88549076 | Development of Preclinical Models to Understand and Treat Colorectal Cancer |
Q34313844 | Dietary fat-influenced development of colon neoplasia in Apc Min mice exposed to benzo(a)pyrene |
Q35005048 | Dietary polyunsaturated fatty acids and colorectal neoplasia. |
Q28592033 | Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells |
Q39592126 | Gene trapping identifies chloride channel 4 as a novel inducer of colon cancer cell migration, invasion and metastases |
Q46320321 | Genetic assessment of the importance of galectin-3 in cancer initiation, progression, and dissemination in mice. |
Q28131737 | Genome maintenance mechanisms for preventing cancer |
Q38111773 | Genomic instability and colon carcinogenesis: from the perspective of genes |
Q37183586 | Growth hormone is permissive for neoplastic colon growth |
Q28510929 | High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading |
Q52844263 | High-frequency ultrasound for in vivo measurement of colon wall thickness in mice. |
Q36157411 | Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. |
Q35003070 | Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia. |
Q35596304 | In vivo biomarkers for targeting colorectal neoplasms. |
Q35083740 | KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations |
Q35193514 | Live bacteria as the basis for immunotherapies against cancer. |
Q86824131 | Modulation of colon cancer by nutmeg |
Q25257401 | Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesis |
Q37831162 | Morphological and molecular alterations in 1,2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats |
Q34150255 | Morphology and Properties of Pericytes |
Q33684472 | Mouse models for cancer stem cell research |
Q26774627 | Mouse models for the discovery of colorectal cancer driver genes |
Q33204054 | Mouse models of human familial cancer syndromes |
Q34234115 | Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes |
Q24308753 | Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription |
Q34382804 | Novel translational strategies in colorectal cancer research |
Q75312804 | Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice |
Q35637318 | Polycyclic aromatic hydrocarbons and digestive tract cancers: a perspective |
Q58050599 | Proteomic Techniques in Colorectal Cancer Research |
Q34554730 | Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways |
Q27931230 | Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs |
Q34772160 | The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies |
Q41819314 | The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice |
Q36860902 | The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals |
Q34514072 | The armadillo repeat domain of Apc suppresses intestinal tumorigenesis. |
Q36232457 | The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells |
Q34989790 | The genetic pathogenesis of colorectal cancer |
Q52901776 | The immune response to sporadic colorectal cancer in a novel mouse model |
Q28077795 | The role of testosterone in colorectal carcinoma: pathomechanisms and open questions |
Q35812510 | Trials, tribulations, and trends in tumor modeling in mice |
Q24336689 | Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets |
Q41956272 | p16(Ink4a) inhibits histologic progression and angiogenic signaling in min colon tumors |
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