Mouse models for colorectal cancer

scientific article

Mouse models for colorectal cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1050284220
P356DOI10.1038/SJ.ONC.1203036
P698PubMed publication ID10498885
P5875ResearchGate publication ID12801246

P2093author name stringYang K
Edelmann W
Kucherlapati R
Lipkin M
Heyer J
P2860cites workIdentification of deletion mutations and three new genes at the familial polyposis locusQ24294229
Identification of c-MYC as a target of the APC pathwayQ24310637
Homeosis and intestinal tumours in Cdx2 mutant miceQ24323758
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouseQ34344768
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologsQ34554581
Dietary fat influences on polyp phenotype in multiple intestinal neoplasia miceQ36084832
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Parallel human genome analysis: microarray-based expression monitoring of 1000 genesQ36825305
Mechanisms and biological effects of mismatch repairQ37041860
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosisQ38293261
Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC geneQ40951183
Familial risk and colorectal cancerQ41264786
DNA loop repair by human cell extractsQ41429743
The role of beta-catenin in cell adhesion, signal transduction, and cancer.Q41702467
Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomasQ42013009
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Mutations in the SMAD4/DPC4 gene in juvenile polyposisQ45345229
CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancerQ47684602
PTEN and inherited hamartoma-cancer syndromesQ47852476
Retinal pigment epithelium abnormalities in mice with adenomatous polyposis coli gene disruption.Q52525509
Suppression of intestinal polyp development by low-fat and high-fiber diet in Apc(delta716) knockout mice.Q53439555
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.Q54558350
Suppression of intestinal neoplasia by DNA hypomethylation.Q54613769
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in miceQ58378937
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc geneQ24562061
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumorsQ24564011
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cellsQ27860717
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesisQ27939891
Lessons from hereditary colorectal cancerQ28131788
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) geneQ28236533
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancerQ28253384
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Association of the APC tumor suppressor protein with cateninsQ28257313
Biochemistry and genetics of eukaryotic mismatch repairQ28282377
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing overQ28282791
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor CellsQ28292781
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancerQ28294774
Mammalian MutS homologue 5 is required for chromosome pairing in meiosisQ28295022
Identification of FAP locus genes from chromosome 5q21Q28300247
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genesQ28508338
MSH2 deficient mice are viable and susceptible to lymphoid tumoursQ28508486
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repairQ28508905
Pten is essential for embryonic development and tumour suppressionQ28509238
Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cystsQ28510629
Meiotic pachytene arrest in MLH1-deficient miceQ28510650
Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and developmentQ28511030
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryoQ28512702
Mutation in the mismatch repair gene Msh6 causes cancer susceptibilityQ28592583
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinomaQ29615026
Mismatch repair in replication fidelity, genetic recombination, and cancer biologyQ29616483
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC geneQ29616490
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1Q29616726
Gene expression profiles in normal and cancer cellsQ29619943
Identification and characterization of the familial adenomatous polyposis coli geneQ29620382
The oncogenic activation of beta-cateninQ33540073
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasiaQ34313013
P433issue38
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)5325-5333
P577publication date1999-09-01
P1433published inOncogeneQ1568657
P1476titleMouse models for colorectal cancer
P478volume18

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