| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1042080593 |
| P356 | DOI | 10.1038/NG1197-271 |
| P3181 | OpenCitations bibliographic resource ID | 3537280 |
| P698 | PubMed publication ID | 9354786 |
| P5875 | ResearchGate publication ID | 13874318 |
| P2093 | author name string | K Tanaka | |
| M Konishi | |||
| T Mori | |||
| M Chiba | |||
| M Koike | |||
| M Miyaki | |||
| M Muraoka | |||
| M Yasuno | |||
| R Kikuchi-Yanoshita | |||
| T Igari | |||
| P2860 | cites work | Mutations of two PMS homologues in hereditary nonpolyposis colon cancer | Q24318484 |
| Mutation of a mutL homolog in hereditary colon cancer | Q28114939 | ||
| The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer | Q28256988 | ||
| Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer | Q28257360 | ||
| Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells | Q28292781 | ||
| GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells | Q28292790 | ||
| Mutations of GTBP in genetically unstable cells | Q28292802 | ||
| Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair | Q29615027 | ||
| Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review | Q40901949 | ||
| Clues to the pathogenesis of familial colorectal cancer | Q42622043 | ||
| Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer | Q48084125 | ||
| Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer. | Q53452567 | ||
| Frameshift mutator mutations | Q57978058 | ||
| Germ line mutations of hMSH2 and hMLH1 genes in Japanese families with hereditary nonpolyposis colorectal cancer (HNPCC): usefulness of DNA analysis for screening and diagnosis of HNPCC patients | Q70951139 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | colorectal cancer | Q188874 |
| colorectal carcinoma | Q25493920 | ||
| Lynch syndrome | Q783644 | ||
| P304 | page(s) | 271-2 | |
| P577 | publication date | 1997-11-01 | |
| P1433 | published in | Nature Genetics | Q976454 |
| P1476 | title | Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer | |
| P478 | volume | 17 |
| Q62977759 | A 10-Mb paracentric inversion of chromosome arm 2p inactivatesMSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North-American kindred |
| Q43199969 | A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening |
| Q77668057 | A modified multiplex PCR assay for detection of large deletions in MSH2 and MLH1 |
| Q44095031 | A novel MSH2 germline mutation in a Druze HNPCC family |
| Q79858923 | A novel MSH2 mutation in a Chinese family with hereditary non-polyposis colorectal cancer |
| Q74073284 | A novel germline 1.8-kb deletion of hMLH1 mimicking alternative splicing: a founder mutation in the Chinese population |
| Q33269177 | A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer |
| Q28283356 | A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer |
| Q35013990 | A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory |
| Q54788578 | A636P is associated with early-onset colon cancer in Ashkenazi Jews. |
| Q35934041 | A636P testing in Ashkenazi Jews |
| Q36416282 | ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes |
| Q28587976 | Acceleration of lymphomagenesis in mismatch-repair deficient mice by exposure to genotoxic agents |
| Q74434710 | Alterations of repeated sequences in 5' upstream and coding regions in colorectal tumors from patients with hereditary nonpolyposis colorectal cancer and Turcot syndrome |
| Q33620910 | An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis. |
| Q35594366 | An insight into the genetic pathway of adenocarcinoma of the small intestine |
| Q38202510 | Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery |
| Q36309767 | Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection |
| Q37686215 | Association between IHC and MSI testing to identify mismatch repair-deficient patients with ovarian cancer |
| Q39232774 | Association between MSH6 G39E polymorphism and cancer susceptibility: a meta-analysis of 7,046 cases and 34,554 controls |
| Q24539206 | Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations. |
| Q35446668 | BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing |
| Q34848218 | Basic concepts for genetic testing in common hereditary colorectal cancer syndromes |
| Q38295926 | Bias in detection of instability of the (C)8 mononucleotide repeat of MSH6 in tumours from HNPCC patients |
| Q34558159 | Biology and genetics of colorectal cancer |
| Q34346199 | Cancer genetics in oncology practice |
| Q39012229 | Cancer predisposition syndromes: lessons for truly precision medicine |
| Q33582756 | Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management |
| Q35971538 | Characterization of two Ashkenazi Jewish founder mutations in MSH6 gene causing Lynch syndrome |
| Q53914199 | Chemotherapy resistant ovarian cancer in carriers of an hMSH2 mutation? |
| Q58006247 | Clinical Definition of Hereditary Non-polyposis Colorectal Cancer: A Search for the Impossible? |
| Q33813997 | Clinical challenges in management of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer |
| Q36932299 | Clinical genomic database |
| Q27692120 | Clinical implications of BRAF mutation test in colorectal cancer |
| Q53331560 | Clinical significance of microsatellite instability in endometrial carcinoma. |
| Q34174654 | Clinicopathological and genetic features of Chinese hereditary nonpolyposis colorectal cancer (HNPCC). |
| Q35782915 | Colorectal cancer as a complex disease: defining at-risk subjects in the general population - a preventive strategy |
| Q41657778 | Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum |
| Q37385768 | Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases |
| Q57567891 | Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer |
| Q35748966 | Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors |
| Q38129858 | Criteria and prediction models for mismatch repair gene mutations: a review. |
| Q21328691 | Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients |
| Q78066993 | Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer |
| Q36527421 | DNA mismatch repair and Lynch syndrome |
| Q34164892 | DNA mismatch repair and cancer |
| Q34568596 | DNA mismatch repair defects: role in colorectal carcinogenesis |
| Q33947053 | DNA mismatch repair genes and colorectal cancer |
| Q28295863 | DNA replication fidelity and cancer |
| Q91212090 | De novo variants in FBXO11 cause a syndromic form of intellectual disability with behavioral problems and dysmorphisms |
| Q33888905 | Deficiency of a novel mismatch repair activity in a bladder tumor cell line |
| Q37164481 | Deficient DNA mismatch repair is common in Lynch syndrome-associated colorectal adenomas |
| Q37235042 | Differences and evolution of the methods for the assessment of microsatellite instability |
| Q50288846 | Dimeric TGFB1 does not bind TGFBR2 MSI frameshift mutants |
| Q34128565 | Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium? |
| Q39297259 | Educational and Psychosocial Support Needs in Lynch Syndrome: Implementation and Assessment of an Educational Workshop and Support Group |
| Q37236178 | Endometrial cancer as a familial tumor: pathology and molecular carcinogenesis (review). |
| Q38454955 | Endometrial cancer: redefining the molecular-targeted approach |
| Q34253892 | Establishing a cancer genetics programme in Asia - the singapore experience |
| Q44841081 | Estimated prevalence of hereditary cancers and the need for surveillance in a Norwegian county, Telemark |
| Q27939116 | Eukaryotic DNA mismatch repair |
| Q61196038 | Evaluation of the replication error phenotype in relation to molecular and clinicopathological features in hereditary and early onset colorectal cancer |
| Q77619057 | Excess of hMLH1 germline mutations in Swiss families with hereditary non-polyposis colorectal cancer |
| Q97539272 | Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges |
| Q36641429 | Extensive molecular screening for hereditary non-polyposis colorectal cancer |
| Q28145436 | Familial endometrial cancer in female carriers of MSH6 germline mutations |
| Q37048169 | Features of trinucleotide repeat instability in vivo |
| Q47791002 | Frameshift mismatch recognition by the human MutS alpha complex |
| Q34756357 | Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases |
| Q35594265 | Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients |
| Q36385676 | Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer |
| Q33739955 | Functional analysis of human mismatch repair gene mutations identifies weak alleles and polymorphisms capable of polygenic interactions |
| Q44745628 | Gene-environment interaction in hereditary nonpolyposis colorectal cancer with implications for diagnosis and genetic testing. |
| Q33681640 | Genetic implications of double primary cancers of the colorectum and endometrium |
| Q34783505 | Genetic insights into familial cancers-- update and recent discoveries |
| Q31464606 | Genetic predisposition and somatic diversification in tumor development and progression |
| Q35930688 | Genetic predisposition to colorectal cancer |
| Q34008801 | Genetic predisposition to colorectal cancer: where we stand and future perspectives |
| Q33764029 | Genetic susceptibility to non-polyposis colorectal cancer |
| Q33814001 | Genetic testing and counseling for hereditary forms of colorectal cancer |
| Q36422099 | Genetic testing for Lynch syndrome: family communication and motivation |
| Q35034265 | Genetic testing for colon cancer: joint statement of the American College of Medical Genetics and American Society of Human Genetics. Joint Test and Technology Transfer Committee Working Group |
| Q34533915 | Genetic testing for high-risk colon cancer patients |
| Q35090219 | Genetic testing for polyposis: practical and ethical aspects. |
| Q33864863 | Genomic instability in multistage carcinogenesis |
| Q36677899 | Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts |
| Q33943737 | Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancers |
| Q42856984 | Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer |
| Q57978009 | Germline and somatic mutations in hMSH6 and hMSH3 in gastrointestinal cancers of the microsatellite mutator phenotype |
| Q35776136 | Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients. |
| Q54116561 | Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers. |
| Q40810320 | Growth inhibition due to complementation of transforming growth factor-beta receptor type II-defect by human chromosome 3 transfer in human colorectal carcinoma cells |
| Q51063696 | Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-society Task Force on colorectal cancer |
| Q93493049 | HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review |
| Q28589491 | HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions |
| Q34098053 | Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression |
| Q28085485 | Hereditary Syndromes Manifesting as Endometrial Carcinoma: How Can Pathological Features Aid Risk Assessment? |
| Q35355789 | Hereditary colorectal cancer in the general population: from cancer registration to molecular diagnosis |
| Q43695489 | Hereditary non-polyposis colorectal cancer/Lynch syndrome in Korean patients with endometrial cancer |
| Q34977063 | Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management |
| Q53414631 | Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability. |
| Q37716875 | History, genetics, and strategies for cancer prevention in Lynch syndrome |
| Q37010994 | Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas. |
| Q79073717 | Identification of germline MSH2 gene mutations in endometrial cancer not fulfilling the new clinical criteria for hereditary nonpolyposis colorectal cancer |
| Q40920177 | Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1. |
| Q36414493 | Identification of miR-215 mediated targets/pathways via translational immunoprecipitation expression analysis (TrIP-chip). |
| Q57729078 | Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing |
| Q57291374 | Impact of colonoscopic screening in Familial Colorectal Cancer Type X |
| Q36392688 | Impact of genetic testing on endometrial cancer risk-reducing practices in women at risk for Lynch syndrome |
| Q33755092 | Incomplete Segregation of MSH6 Frameshift Variants with Phenotype of Lynch Syndrome |
| Q49452061 | Inflammation-associated microsatellite alterations: Mechanisms and significance in the prognosis of patients with colorectal cancer |
| Q57742300 | Inherited susceptibility to colorectal adenomas and carcinomas: Evidence for a new predisposition gene on 15q14-q22 |
| Q22003969 | Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer |
| Q42824675 | Investigating of microsatellites instability in patients with hereditary non-polyposis colorectal cancer in Isfahan |
| Q77537643 | Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation |
| Q35954134 | Is surveillance of the small bowel indicated for Lynch syndrome families? |
| Q62978070 | Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report |
| Q34204951 | Little evidence for involvement of MLH3 in colorectal cancer predisposition |
| Q62978214 | Long Term Follow-up of HNPCC Gene Mutation Carriers: Compliance with Screening and Satisfaction with Counseling and Screening Procedures |
| Q36784982 | Loss of DNA mismatch repair protein hMSH6 in ovarian cancer is histotype-specific |
| Q54760397 | Low mutation rate of hMSH2 and hMLH1 in Taiwanese hereditary non-polyposis colorectal cancer. |
| Q35777640 | Low prevalence of germline hMSH6 mutations in colorectal cancer families from Spain |
| Q47141178 | Lynch II syndrome: a case report. |
| Q36246487 | Lynch syndrome genes |
| Q37254339 | MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer |
| Q37423053 | MLH1 promoter germline-methylation in selected probands of Chinese hereditary non-polyposis colorectal cancer families |
| Q22010995 | MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability |
| Q62068013 | MSH-6: extending the reliability of immunohistochemistry as a screening tool in Muir–Torre syndrome |
| Q62977773 | MSH2 genomic deletions are a frequent cause of HNPCC |
| Q33933576 | MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer. |
| Q36695748 | MSH6 missense mutations are often associated with no or low cancer susceptibility |
| Q28295022 | Mammalian MutS homologue 5 is required for chromosome pairing in meiosis |
| Q37506265 | Meta-analysis of MSH6 gene mutation frequency in colorectal and endometrial cancers |
| Q89782419 | Microsatellite Instability and MMR Genes Abnormalities in Canine Mammary Gland Tumors |
| Q31164885 | Microsatellite analysis of hereditary nonpolyposis colorectal cancer-associated colorectal adenomas by laser-assisted microdissection: correlation with mismatch repair protein expression provides new insights in early steps of tumorigenesis |
| Q36289277 | Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps |
| Q44201536 | Microsatellite instability and loss of heterozygosity of tumor suppressor genes in Bosnian patients with sporadic colorectal cancer |
| Q24627393 | Microsatellite instability in colorectal cancer |
| Q73758307 | Microsatellite instability in squamous cell carcinoma of head and neck from the Indian patient population |
| Q64101180 | Microsatellite instability is inversely associated with type 2 diabetes mellitus in colorectal cancer |
| Q35355631 | Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer |
| Q34217505 | Microsatellite instability: application in hereditary non-polyposis colorectal cancer. |
| Q43864989 | Milestones of Lynch syndrome: 1895-2015. |
| Q47291374 | Minichromosome maintenance complex component 6 (MCM6) expression correlates with histological grade and survival in endometrioid endometrial adenocarcinoma |
| Q38895750 | Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade |
| Q33885063 | Mismatch repair defects in cancer |
| Q38741029 | Mismatch repair deficiency testing in clinical practice |
| Q38262826 | Mismatch repair genes founder mutations and cancer susceptibility in Lynch syndrome. |
| Q46111533 | Mismatch repair protein expression and microsatellite instability: a comparison of clear cell sarcoma of soft parts and metastatic melanoma |
| Q33904639 | Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene |
| Q42379696 | Molecular analysis: microsatellity instability and loss of heterozygosity of tumor suppressor gene in hereditary non-polyposis colorectal cancers (HNPCC). |
| Q37360286 | Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant |
| Q36772096 | Molecular carcinogenesis of endometrial cancer |
| Q57316220 | Molecular characterization of the spectrum of genomic deletions in the mismatch repair genesMSH2,MLH1,MSH6, andPMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC) |
| Q33670210 | Molecular diagnostics of cancer predisposition: hereditary non-polyposis colorectal carcinoma and mismatch repair defects |
| Q28205777 | Molecular dimensions of gastrointestinal tumors: Some thoughts for digestion |
| Q24617331 | Molecular origins of cancer: Molecular basis of colorectal cancer |
| Q35433209 | Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer |
| Q33739279 | Mouse models for colorectal cancer |
| Q39844167 | Mph1 requires mismatch repair-independent and -dependent functions of MutSalpha to regulate crossover formation during homologous recombination repair |
| Q34386209 | Muir-Torre phenotype has a frequency of DNA mismatch-repair-gene mutations similar to that in hereditary nonpolyposis colorectal cancer families defined by the Amsterdam criteria |
| Q33759595 | Muir-Torre syndrome: case report of a patient with concurrent jejunal and ureteral cancer and a review of the literature |
| Q73173931 | Multiple sites required for expression in 5'-flanking region of the hMLH1 gene |
| Q81602162 | Mutational analysis of hMsh6 in Israeli HNPCC and HNPCC-like families |
| Q87606540 | Mutational dynamics of early and late relapsed childhood ALL: rapid clonal expansion and long-term dormancy |
| Q52720227 | Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers. |
| Q79198177 | Mutations of the 'minor' mismatch repair gene MSH6 in typical and atypical hereditary nonpolyposis colorectal cancer |
| Q35790060 | Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer |
| Q38421164 | Novel LOVD databases for hereditary breast cancer and colorectal cancer genes in the Chinese population |
| Q41711225 | Novel dominant mutations in Saccharomyces cerevisiae MSH6. |
| Q51819338 | Occult endometrial cancer and decision making for prophylactic hysterectomy in hereditary nonpolyposis colorectal cancer patients. |
| Q28066110 | Opportunities for immunotherapy in microsatellite instable colorectal cancer |
| Q36510713 | Optimizing the detection of hereditary non-polyposis colorectal cancer: an update. |
| Q27024662 | PMS2 monoallelic mutation carriers: the known unknown |
| Q34975960 | Pathogenesis and clinical management of hereditary non-polyposis colorectal cancer |
| Q34160157 | Pathogenesis of colorectal cancer |
| Q78732134 | Pathogenesis of colorectal cancer |
| Q33910331 | Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history |
| Q51023349 | Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer. |
| Q46324177 | Phenotypic and genotypic heterogeneity of Lynch syndrome: a complex diagnostic challenge |
| Q36882484 | Prediction of germline mutations and cancer risk in the Lynch syndrome |
| Q83529174 | Predictive and prognostic markers in colorectal cancer |
| Q35595893 | Prevalence and incidence of hyperplastic polyps and adenomas in familial colorectal cancer: correlation between the two types of colon polyps |
| Q37103047 | Prevalence of adenomas and hyperplastic polyps in mismatch repair mutation carriers among CAPP2 participants: report by the colorectal adenoma/carcinoma prevention programme 2. |
| Q35022384 | Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers |
| Q57591232 | Prevalence of germline mutations ofMLH1 andMSH2 in hereditary nonpolyposis colorectal cancer families from Spain |
| Q34583335 | Prevention and chemoprevention of colorectal neoplasms |
| Q34190072 | Preventive surgery for colon cancer in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer syndrome |
| Q33887815 | Prioritizing candidate disease genes by network-based boosting of genome-wide association data. |
| Q35791897 | Proportion and phenotype of MYH-associated colorectal neoplasia in a population-based series of Finnish colorectal cancer patients |
| Q58408439 | Prédispositions héréditaires au cancer colorectal |
| Q30743260 | Realizing the promise of cancer predisposition genes |
| Q36484887 | Recently identified colon cancer predispositions: MYH and MSH6 mutations |
| Q74610810 | Reduction in hMSH2 mRNA levels by premature translation termination: implications for mutation screening in hereditary nonpolyposis colorectal cancer |
| Q37477005 | Reflex test reminders in required cancer synoptic templates decrease order entry error: An analysis of mismatch repair immunohistochemical orders to screen for Lynch syndrome |
| Q37056141 | Regulation of the Human MSH6 Gene by the Sp1 Transcription Factor and Alteration of Promoter Activity and Expression by Polymorphisms |
| Q34612512 | Requirement for Msh6, but not for Swi4 (Msh3), in Msh2-dependent repair of base-base mismatches and mononucleotide loops in Schizosaccharomyces pombe |
| Q34975833 | Review article: genetic testing and counselling for hereditary colorectal cancer |
| Q104135139 | SVA retrotransposon insertion in exon of MMR genes results in aberrant RNA splicing and causes Lynch syndrome |
| Q48654808 | Screening for germline mutations in mismatch repair genes in patients with Lynch syndrome by next generation sequencing |
| Q35438561 | Screening for microsatellite instability target genes in colorectal cancers. |
| Q35435690 | Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. |
| Q38314848 | Sequence analysis of the mismatch repair gene hMSH6 in the germline of patients with familial and sporadic colorectal cancer |
| Q73143600 | Signaling mismatch repair in cancer |
| Q42616545 | Single-amplicon MSH2 A636P mutation testing in Ashkenazi Jewish patients with colorectal cancer: role in presurgical management |
| Q24803238 | Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype |
| Q26823199 | Somatic mosaicism in the human genome |
| Q40878184 | Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability |
| Q27641634 | Structural variation in PWWP domains |
| Q33769290 | Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicity |
| Q37274864 | Synchronous occult cancers of the endometrium and fallopian tube in an MSH2 mutation carrier at time of prophylactic surgery |
| Q64934285 | Systematic Review: An Update on the Spectrum of Urological Malignancies in Lynch Syndrome. |
| Q53398388 | Systematic identification of genes with coding microsatellites mutated in DNA mismatch repair-deficient cancer cells. |
| Q37128242 | Systematic review and meta-analysis of ovarian cancers: estimation of microsatellite-high frequency and characterization of mismatch repair deficient tumor histology |
| Q36627936 | The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair |
| Q63966105 | The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome |
| Q73115286 | The Muir-Torre syndrome in kindreds with hereditary nonpolyposis colorectal cancer (Lynch syndrome): A classic obligation in preventive medicine |
| Q28507079 | The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin |
| Q33901159 | The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation? |
| Q57741867 | The added value of PMS2 immunostaining in the diagnosis of hereditary nonpolyposis colorectal cancer |
| Q33762979 | The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside |
| Q28066460 | The biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized care |
| Q55067670 | The concise handbook of family cancer syndromes. Mayo Familial Cancer Program. |
| Q28077234 | The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery |
| Q34989790 | The genetic pathogenesis of colorectal cancer |
| Q47739281 | The genetics of hereditary common cancers |
| Q37038987 | The history of Lynch syndrome |
| Q37420429 | The identification of Lynch syndrome in British Columbia |
| Q28137782 | The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer |
| Q42027522 | The mRNA level of MLH1 in peripheral blood is a biomarker for the diagnosis of hereditary nonpolyposis colorectal cancer |
| Q46688108 | The mechanism of microsatellite instability is different in synchronous and metachronous colorectal cancer |
| Q35037873 | The molecular and genetic basis of colon cancer |
| Q54320805 | The molecular basis of EPCAM expression loss in Lynch syndrome-associated tumors. |
| Q90953408 | The practice of universal screening for Lynch syndrome in newly diagnosed endometrial carcinoma |
| Q36615234 | The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers |
| Q35435480 | The role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancers |
| Q40281420 | The silent mutation MLH1 c.543C>T resulting in aberrant splicing can cause Lynch syndrome: a case report |
| Q40597964 | Three new mutations in hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay |
| Q33298821 | Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families |
| Q34384230 | Transcriptome profiling of the cancer, adjacent non-tumor and distant normal tissues from a colorectal cancer patient by deep sequencing |
| Q52577954 | Tumor development in Japanese patients with Lynch syndrome. |
| Q33890086 | Tumour suppressor gene mutations in humans and mice: parallels and contrasts |
| Q57714843 | Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect |
| Q47604676 | Unusual tumors associated with the hereditary nonpolyposis colorectal cancer syndrome |
| Q36890349 | Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients |
| Q24322575 | WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma |
| Q50785085 | What is the appropriate screening protocol in Lynch syndrome? |
| Q82288276 | [Hereditary colorectal cancer] |
| Q54442531 | [Inherited tumors of the gastrointestinal tract. Diagnosis and therapeutic aspects]. |
| Q44470300 | hMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from southern Sweden |
| Q40864619 | hMSH6 deficiency and inactivation of the alphaE-catenin invasion-suppressor gene in HCT-8 colon cancer cells. |
Search more.