A636P testing in Ashkenazi Jews

scientific article

A636P testing in Ashkenazi Jews is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S10689-004-0899-Z
P698PubMed publication ID15516845
P5875ResearchGate publication ID8203281

P50authorKenneth OffitQ20732365
P2093author name stringKhedoudja Nafa
Nathan A Ellis
Harvey G Moore
Jose G Guillem
Arnold J Markowitz
Emily Glogowski
Rob Finch
Crystal Palmer
P2860cites workFamilial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.Q54559294
A636P is associated with early-onset colon cancer in Ashkenazi Jews.Q54788578
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the DiseaseQ57567959
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda GuidelinesQ57978042
Clinical Findings with Implications for Genetic Testing in Families with Clustering of Colorectal CancerQ58006261
Clustering of colorectal cancer in families of probands under 40 years of ageQ71513218
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancerQ28253384
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Gastrointestinal polyposis syndromesQ33599177
Clinical implications of genetic testing of hereditary nonpolyposis colorectal cancerQ33764554
Genetic anthropology of the colorectal cancer-susceptibility allele APC I1307K: evidence of genetic drift within the AshkenazimQ33905286
MSH2 c.1452-1455delAATG is a founder mutation and an important cause of hereditary nonpolyposis colorectal cancer in the southern Chinese populationQ33909800
The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish populationQ34161196
Recurrent germline mutation in MSH2 arises frequently de novoQ35435822
Genetic instability occurs in the majority of young patients with colorectal cancerQ38297232
Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes.Q40770785
Age and origin of two common MLH1 mutations predisposing to hereditary colon cancerQ42011353
Multiple HNPCC tumours: ask the family!Q43087314
A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screeningQ43199969
Population-based molecular detection of hereditary nonpolyposis colorectal cancerQ43783854
A founder mutation of the MSH2 gene and hereditary nonpolyposis colorectal cancer in the United StatesQ46655105
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindredQ48044118
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
Hereditary susceptibility to colorectal cancer. Relatives of early onset cases are particularly at risk.Q52869239
P433issue3-4
P304page(s)223-227
P577publication date2004-01-01
P1433published inFamilial CancerQ15761917
P1476titleA636P testing in Ashkenazi Jews
P478volume3

Reverse relations

cites work (P2860)
Q44095031A novel MSH2 germline mutation in a Druze HNPCC family
Q36808349High risk of colorectal and endometrial cancer in Ashkenazi families with the MSH2 A636P founder mutation
Q55465499Homozygosity of MSH2 c.1906G-->C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I.
Q51889166Mutation spectrum in HNPCC in the Israeli population.

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