| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1039430816 |
| P356 | DOI | 10.1038/NM0495-348 |
| P698 | PubMed publication ID | 7585065 |
| P50 | author | Kenneth W. Kinzler | Q28031580 |
| Bert Vogelstein | Q827502 | ||
| Malcolm G. Dunlop | Q37371270 | ||
| Gloria M Petersen | Q95972100 | ||
| P2093 | author name string | Liu B | |
| Fujiwara T | |||
| Parsons R | |||
| Hamilton SR | |||
| Papadopoulos N | |||
| Jen J | |||
| Wyllie AH | |||
| Farrington SM | |||
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| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | patient | Q181600 |
| colorectal cancer | Q188874 | ||
| P304 | page(s) | 348-352 | |
| P577 | publication date | 1995-04-01 | |
| P1433 | published in | Nature Medicine | Q1633234 |
| P1476 | title | Genetic instability occurs in the majority of young patients with colorectal cancer | |
| P478 | volume | 1 |
| Q46861521 | A comparative microsatellite analysis of colorectal cancer in patients <35 years and >50 years of age. |
| Q47342245 | A mutational comparison of adult and adolescent and young adult (AYA) colon cancer. |
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| Q47736618 | A novel missense mutation and frameshift mutations in the type II receptor of transforming growth factor-beta gene in sporadic colon cancer with microsatellite instability |
| Q54788578 | A636P is associated with early-onset colon cancer in Ashkenazi Jews. |
| Q35934041 | A636P testing in Ashkenazi Jews |
| Q37383704 | APC mutations in colorectal tumors with mismatch repair deficiency |
| Q37640674 | Allelic imbalance and microsatellite instability of the DCC gene in colorectal cancer in patients under the age of 35 using fluorescent DNA technology |
| Q36637607 | Alternative genetic pathways in colorectal carcinogenesis. |
| Q57570041 | Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients |
| Q37425820 | Aspirin, salicylates, and cancer. |
| Q36761302 | Association Between Younger Age and Targetable Genomic Alterations and Prognosis in Non-Small-Cell Lung Cancer |
| Q55033193 | BAT-26 identifies sporadic colorectal cancers with mutator phenotype: a correlative study with clinico-pathological features and mutations in mismatch repair genes. |
| Q36717196 | Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma |
| Q57569922 | Cascade genetic testing for mismatch repair gene mutations |
| Q58862209 | Causes of microsatellite instability in colorectal tumors |
| Q71970798 | Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer |
| Q42134566 | Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair |
| Q33813997 | Clinical challenges in management of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer |
| Q33655292 | Colorectal cancer in adolescents. |
| Q38283945 | Colorectal cancer in young adults |
| Q33706262 | Colorectal cancer screening |
| Q36431615 | Colorectal carcinoma in Hong Kong: epidemiology and genetic mutations. |
| Q77983932 | Comparison of three methods of microsatellite detection |
| Q33677624 | Complex genetic predisposition to cancer in an extended HNPCC family with an ancestral hMLH1 mutation. |
| Q37145772 | Concordance with clinical practice guidelines for adjuvant chemotherapy in patients with stage I-III colon cancer: experience in 2 Canadian provinces |
| Q36643467 | Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients |
| Q43614950 | Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast |
| Q34102586 | Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer |
| Q34568596 | DNA mismatch repair defects: role in colorectal carcinogenesis |
| Q41536289 | DNA mismatch repair in mammals: role in disease and meiosis |
| Q41264767 | DNA repair and colorectal cancer |
| Q71520203 | Diagnostic use of microsatellite instability in hereditary non-polyposis colorectal cancer |
| Q34622391 | Differences in K-ras and mitochondrial DNA mutations and microsatellite instability between colorectal cancers of Vietnamese and Japanese patients. |
| Q30308834 | Direct analysis for familial adenomatous polyposis mutations |
| Q34012713 | Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients. |
| Q46778172 | Does mutation of transforming growth factor-beta type II receptor gene play an important role in colorectal polyps? |
| Q57570007 | Early-onset colorectal cancer with stable microsatellite DNA and near-diploid chromosomes |
| Q33350295 | Early-onset gastric cancer: Learning lessons from the young |
| Q36749671 | Evaluating Lynch syndrome in very early onset colorectal cancer probands without apparent polyposis |
| Q40750391 | Evaluation of colonoscopic sized biopsies for microsatellite instability and adenomatous polyposis coli (APC) variants |
| Q61196038 | Evaluation of the replication error phenotype in relation to molecular and clinicopathological features in hereditary and early onset colorectal cancer |
| Q38489602 | Evidence for an age-related influence of microsatellite instability on colorectal cancer survival |
| Q38466084 | Exome sequencing to detect rare variants associated with general cognitive ability: a pilot study. |
| Q47960692 | Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability |
| Q36641429 | Extensive molecular screening for hereditary non-polyposis colorectal cancer |
| Q36141256 | Extracolonic features of familial adenomatous polyposis in patients with sporadic colorectal cancer |
| Q41264786 | Familial risk and colorectal cancer |
| Q41697780 | Family history of cancer in children and young adults with colorectal cancer |
| Q55449475 | Frameshift mutations of the hMSH6 gene in human leukemia cell lines. |
| Q35594265 | Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients |
| Q30470281 | Genes driving the colonoscope. |
| Q50302961 | Genes for Prader Willi syndrome/Angelman syndrome and fragile X syndrome are homologous, with genetic imprinting and unstable trinucleotide repeats causing mental retardation, autism and aggression |
| Q51896941 | Genetic alterations of K‐ras may reflect prognosis in stage III colon cancer patients below 60 years of age |
| Q64982538 | Genomic alterations and survival in young patients aged under 40 years with completely resected non-small cell lung cancer. |
| Q52859644 | Genomic deletions in MSH2 or MLH1 are a frequent cause of hereditary non-polyposis colorectal cancer: identification of novel and recurrent deletions by MLPA. |
| Q36115550 | Genomic loci susceptible to replication errors in cancer cells |
| Q57266882 | Germline E-cadherin Gene (CDH1) Mutations Predispose to Familial Gastric Cancer and Colorectal Cancer |
| Q42005199 | Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer |
| Q38361824 | Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers. |
| Q41073930 | Growth stimulation of tumor-specific cytotoxic T lymphocytes on concanavalin a-immobilized carrier beads |
| Q34526950 | Guidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers syndrome |
| Q35355789 | Hereditary colorectal cancer in the general population: from cancer registration to molecular diagnosis |
| Q41045332 | Hereditary nonpolyposis colorectal cancer: review of clinical, molecular genetics, and counseling aspects |
| Q55005128 | High rate of induction of human autologous cytotoxic T lymphocytes against renal carcinoma cells cultured with an interleukin cocktail. |
| Q37518592 | High-resolution characterization of CPD hotspot formation in human fibroblasts |
| Q33948312 | Hypermutability at a poly(A/T) tract in the human germline |
| Q39888827 | Immortalization of normal human gingival keratinocytes and cytological and cytogenetic characterization of the cells |
| Q57285929 | Immunohistochemistry detects mismatch repair gene defects in colorectal cancer |
| Q39402769 | Incidence of colorectal cancer in young patients |
| Q41738452 | Increased frequency of mutations in DNA from infertile men with meiotic arrest |
| Q54498867 | Influence of age on adenomatous polyposis coli and p53 mutation frequency in sporadic colorectal cancer-rarity of co-occurrence of mutations in APC, K-ras, and p53 genes. |
| Q37239487 | Infrequent loss of heterozygosity of APC/MCC and DCC genes in gastric cancer showing DNA microsatellite instability |
| Q41352120 | Inheritance and susceptibility to tumours of the large bowel: a new classification of colorectal malignancies. |
| Q40705179 | Loss of heterozygosity on chromosome 7q in in vitro-immortalized human oral keratinocyte cell lines |
| Q55034846 | Loss or somatic mutations of hMSH2 occur in hereditary nonpolyposis colorectal cancers with hMSH2 germline mutations. |
| Q34242626 | Low frequency of Lynch syndrome among young patients with non-familial colorectal cancer |
| Q33897441 | Lung adenocarcinoma patients of young age have lower EGFR mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors. |
| Q57741862 | Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics |
| Q74323855 | MLH1 and MSH2 constitutional mutations in colorectal cancer families not meeting the standard criteria for hereditary nonpolyposis colorectal cancer |
| Q34545271 | MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer |
| Q28203826 | Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair |
| Q59944728 | Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair |
| Q37930489 | MicroRNA Dysregulation in Colon Cancer Microenvironment Interactions: The Importance of Small Things in Metastases. |
| Q46781654 | Microsatellite analysis of the DCC gene in nephroblastomas: pathologic correlations and prognostic implications |
| Q53425970 | Microsatellite instability and aneuploidy rate in young colorectal-cancer patients do not differ significantly from those in older patients. |
| Q34723085 | Microsatellite instability and its relevance to cutaneous tumorigenesis |
| Q35753493 | Microsatellite instability and mutation of DNA mismatch repair genes in gliomas. |
| Q47181135 | Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer. |
| Q35363901 | Microsatellite instability and the clinicopathological features of sporadic colorectal cancer |
| Q73554869 | Microsatellite instability in colorectal-cancer patients with suspected genetic predisposition |
| Q33678081 | Microsatellite instability in early onset and familial colorectal cancer. |
| Q36338134 | Microsatellite instability in gastrointestinal tract cancers: a brief update |
| Q28305319 | Microsatellite instability in human solid tumors |
| Q38345275 | Microsatellite instability in lung cancer patients 40 years of age or younger |
| Q74290555 | Microsatellite instability is uncommon in young patients with renal cell carcinoma |
| Q33938926 | Microsatellite instability markers in breast cancer: a review and study showing MSI was not detected at 'BAT 25' and 'BAT 26' microsatellite markers in early-onset breast cancer |
| Q36618286 | Microsatellite instability, Epstein-Barr virus, mutation of type II transforming growth factor beta receptor and BAX in gastric carcinomas in Hong Kong Chinese |
| Q35355631 | Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer |
| Q40483766 | Microsatellite instability. Shifting concepts in tumorigenesis |
| Q34217505 | Microsatellite instability: application in hereditary non-polyposis colorectal cancer. |
| Q54102997 | Microsatellite instability: impact on cancer progression in proximal and distal colorectal cancers. |
| Q38472647 | Microsatellite markers in leukaemia and lymphoma: comments on a timely topic |
| Q41170340 | Mismatch repair defects in human carcinogenesis |
| Q35129256 | Mismatch repair proficiency and in vitro response to 5-fluorouracil |
| Q82521439 | Molecular Genetics of Colorectal Cancer |
| Q34622005 | Molecular aspects of melanocytic dysplastic nevi |
| Q41686589 | Molecular biology of colorectal cancer |
| Q78167044 | Molecular characteristics of poorly differentiated adenocarcinoma and signet-ring-cell carcinoma of colorectum |
| Q54478476 | Molecular genetic alterations and clinical features in early-onset colorectal carcinomas and their role for the recognition of hereditary cancer syndromes. |
| Q41458471 | Molecular genetics of colorectal cancer (Part 2). |
| Q36291749 | Molecular pathogenesis of sporadic duodenal cancer |
| Q35433209 | Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer |
| Q77495447 | Mononucleotide repeat instability is infrequent in neuroblastoma |
| Q84372973 | Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups |
| Q24318892 | Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair |
| Q74223885 | Mutations associated with microsatellite unstable colorectal carcinomas exhibit widespread intratumoral heterogeneity |
| Q71970804 | Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instability |
| Q53448774 | Mutations of the transforming growth factor-beta type II receptor gene are strongly related to sporadic proximal colon carcinomas with microsatellite instability. |
| Q28235642 | Mutations predisposing to hereditary nonpolyposis colorectal cancer |
| Q41099814 | Mutator genes and mosaicism in colorectal cancer |
| Q40969554 | Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome). |
| Q34975960 | Pathogenesis and clinical management of hereditary non-polyposis colorectal cancer |
| Q24793045 | Predominance of CIN versus MSI in the development of rectal cancer at young age. |
| Q34633911 | Prevalence of pathological germline mutations of hMLH1 and hMSH2 genes in colorectal cancer |
| Q35875960 | Prognosis in DNA mismatch repair deficient colorectal cancer: are all MSI tumours equivalent? |
| Q38473008 | Prognostic significance of DNA replication errors in young patients with colorectal cancer |
| Q85155982 | Prospective Immunohistochemical Analysis of Primary Colorectal Cancers for Loss of Mismatch Repair Protein Expression |
| Q36598199 | Recent advances. Medical genetics |
| Q53998721 | Relationship between grade of microsatellite instability and target genes of mismatch repair pathways in sporadic colorectal carcinoma. |
| Q34975833 | Review article: genetic testing and counselling for hereditary colorectal cancer |
| Q24610838 | Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications |
| Q38422078 | Risk of developing advanced colorectal neoplasia after removing high-risk adenoma detected at index colonoscopy in young patients: A KASID study |
| Q40656410 | Role of microsatellites instability in carcinogenesis of postcricoid carcinoma on top of plummer-vinson syndrome |
| Q57569990 | Screening for exonic copy number mutations at MSH2 and MLH1 by MAPH |
| Q43226430 | Screening for familial colorectal cancer |
| Q41313487 | Screening of patients with a positive family history of colorectal cancer. |
| Q34366761 | Single nucleotide polymorphism seeking long term association with complex disease |
| Q38109817 | Sporadic carcinoma of the colon-rectum in young patients: a distinct disease? A critical review. |
| Q77413342 | Stability of microsatellites in myeloid neoplasias |
| Q71803120 | Testing for cancer genes: Decisions, decisions |
| Q34786141 | The "comparative growth assay": examining the interplay of anti-cancer agents with cells carrying single gene alterations |
| Q57240725 | The Labyrinthine Ways of Cancer Immunotherapy–T Cell, Tumor Cell Encounter: “How Do I Lose Thee? Let Me Count the Ways” |
| Q30234889 | The Rising Incidence of Younger Patients With Colorectal Cancer: Questions About Screening, Biology, and Treatment |
| Q28594399 | The absence of Msh2 alters abelson virus pre-B-cell transformation by influencing p53 mutation |
| Q40849233 | The genetics of inherited colon cancer |
| Q41194136 | The genotype of the human cancer cell: implications for risk analysis. |
| Q41438677 | The natural somatic mutation frequency and human carcinogenesis. |
| Q34394951 | The pathobiology of pulmonary hypertension. Endothelium |
| Q44628695 | The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study |
| Q41736390 | The role of microsatellite instability in gastric carcinoma |
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| Q34820332 | Unique characteristics of adolescent and young adult acute lymphoblastic leukemia, breast cancer, and colon cancer |
| Q40344816 | Unique prevalence of oncogenic genetic alterations in young patients with lung adenocarcinoma |
| Q81160714 | Value of microsatellite instability typing in detecting hereditary non-polyposis colorectal cancer. A prospective multicentric study by the Association Aquitaine Gastro |
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