Molecular Genetics of Colorectal Cancer

scientific article published on 01 January 2011

Molecular Genetics of Colorectal Cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1146/ANNUREV-PATHOL-011110-130235
P953full work available at URLhttp://arjournals.annualreviews.org/doi/abs/10.1146/annurev-pathol-011110-130235
https://www.annualreviews.org/doi/pdf/10.1146/annurev-pathol-011110-130235
P698PubMed publication ID21090969

P2093author name stringEric R. Fearon
P2860cites workBiochimica et Biophysica ActaQ864239
Cancer ResearchQ326097
Hypermutability and mismatch repair deficiency in RER+ tumor cellsQ41508298
Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin.Q41825735
Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomasQ42013009
Clues to the pathogenesis of familial colorectal cancerQ42622043
Altered growth of human colon cancer cell lines disrupted at activated Ki-rasQ42810367
Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.Q42827942
Prospective results of surveillance colonoscopy in dominant familial colorectal cancer with and without Lynch syndromeQ44371959
Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancersQ44779665
FBXW7/hCDC4 is a general tumor suppressor in human cancer.Q45345209
Mutant p53 protein localized in the cytoplasm inhibits autophagyQ46345867
Clinical and genetic findings in an Ashkenazi Jewish population with colorectal neoplasmsQ46549856
Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors.Q46803723
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotypeQ53445992
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APCQ54559294
RAS oncogenes: the first 30 years.Q55036584
Alterations in DNA Methylation: A Fundamental Aspect of NeoplasiaQ56418625
Hereditary factors in cancer. Study of two large midwestern kindredsQ56482519
Familial Adenomatous PolyposisQ56486183
RAF/RAS oncogenes and mismatch-repair statusQ57281056
Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancerQ58862199
Cytogenetics of colorectal adenocarcinomasQ68786733
Hypomethylation of DNA from benign and malignant human colon neoplasmsQ69381419
Hereditary colorectal cancerQ73088287
Loss of IGF2 imprinting: a potential marker of colorectal cancer riskQ73128690
Identification of critical CpG sites for repression of L1 transcription by DNA methylationQ73378476
Mutations of p53 gene in human colorectal cancer: distinct frameshifts among populationsQ73687941
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli proteinQ24291288
Identification of c- MYC as a Target of the APC PathwayQ24310637
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cellsQ24314491
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathwaysQ24317164
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancerQ24319963
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instabilityQ24319995
Familial colorectal cancer type X: the other half of hereditary nonpolyposis colon cancer syndromeQ24594612
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shoresQ24649374
Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancersQ24649562
Regulation of autophagy by cytoplasmic p53Q24651258
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancersQ24656162
Seminars in gastrointestinal diseaseQ27714056
Stage-specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesisQ79252702
CpG island methylator phenotype in cancerQ81080870
Frequency of familial colon cancer and hereditary nonpolyposis colorectal cancer (Lynch syndrome) in a large population databaseQ81149391
Effects of oncogenic p110alpha subunit mutations on the lipid kinase activity of phosphoinositide 3-kinaseQ81314502
Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- statusQ81946858
Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastasesQ82657420
A genetic model for colorectal tumorigenesisQ27860582
The functions of animal microRNAsQ27860621
The genomic landscapes of human breast and colorectal cancersQ27861078
MicroRNA expression profiles classify human cancersQ28032481
High frequency of mutations of the PIK3CA gene in human cancersQ28131776
Lessons from hereditary colorectal cancerQ28131788
Statins and the risk of colorectal cancerQ28176056
Colorectal cancer preventionQ28212789
Genetic instability in human mismatch repair deficient cancersQ28214754
New insights into TGF-beta-Smad signallingQ28260517
Low frequency of AXIN2 mutations and high frequency of MUTYH mutations in patients with multiple polyposisQ28260891
Genetic mapping of a locus predisposing to human colorectal cancerQ28268634
Colorectal cancer and genetic alterations in the Wnt pathwayQ28276998
Genetic alterations during colorectal-tumor developmentQ28281200
Clonal analysis of human colorectal tumorsQ28283169
Identification of mismatch repair genes and their role in the development of cancerQ28288647
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activityQ28294122
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinBQ28508041
Blinded by the Light: The Growing Complexity of p53Q29547590
Cancer statistics, 2009Q29547625
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancerQ29614277
Phenotypic plasticity and the epigenetics of human diseaseQ29614515
Gene silencing in cancer in association with promoter hypermethylationQ29617274
Genetic instability in colorectal cancersQ29618711
Microsatellite instability in cancer of the proximal colonQ29620692
Modulation of microRNA processing by p53Q29620776
Mutations in the APC gene and their implications for protein structure and functionQ30418378
LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instabilityQ33283510
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profilingQ33520213
Colorectal cancer: molecules and populationsQ33652932
Population-based family history-specific risks for colorectal cancer: a constellation approachQ33699254
Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiologyQ33954537
Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based studyQ34102606
Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancersQ34138113
Allelotype of colorectal carcinomasQ34461209
Revving the Throttle on an oncogene: CDK8 takes the driver seatQ37389726
The impact of dietary and lifestyle risk factors on risk of colorectal cancer: a quantitative overview of the epidemiological evidence.Q37436205
MYC-induced cancer cell energy metabolism and therapeutic opportunitiesQ37438881
Cytoplasmic functions of the tumour suppressor p53.Q37466228
MicroRNAs, ultraconserved genes and colorectal cancersQ37508276
MicroRNAs in colorectal cancer: translation of molecular biology into clinical applicationQ37632608
DNA methylation markers in colorectal cancerQ37687919
Genetic instability occurs in the majority of young patients with colorectal cancerQ38297232
Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer.Q38934630
A dual role of p53 in the control of autophagyQ39964629
TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcriptionQ40302206
DNA demethylation and pericentromeric rearrangements of chromosome 1Q41087672
Very high risk of cancer in familial Peutz-Jeghers syndromeQ34512286
CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.Q34561921
Peutz-Jeghers syndrome: clinicopathology and molecular alterationsQ34570577
The role of the APC tumor suppressor in chromosomal instabilityQ34596019
Microsatellite instability in colorectal cancer-the stable evidenceQ34616565
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor geneQ34690901
Natural history of untreated colonic polyps.Q34691452
Cancer family “G” revisited: 1895-1970Q34701495
Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study WorkgroupQ34728738
Beta-catenin hits chromatin: regulation of Wnt target gene activationQ34967116
PTEN hamartoma tumor syndrome: an overviewQ34996547
The role of Myc-induced protein synthesis in cancerQ35014312
BRAF mutations in aberrant crypt foci and hyperplastic polyposisQ35083792
Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcomeQ35588576
Genomic instability and colon cancerQ35682092
Diagnosis and management of dysplasia in patients with inflammatory bowel diseasesQ35787460
Genetic conditions associated with intestinal juvenile polypsQ35841136
Risk of colorectal cancer in juvenile polyposisQ36013971
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerQ36103305
MutYH (MYH) and colorectal cancerQ36206408
Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancerQ36487126
Mutations of TGFbeta signaling molecules in human diseaseQ36606635
Classification of colorectal cancer based on correlation of clinical, morphological and molecular featuresQ36699559
The many ways of Wnt in cancerQ36701583
DNA methylation: the nuts and bolts of repressionQ36914335
The genetics of hereditary colon cancerQ36972251
The Fbxw7/hCdc4 tumor suppressor in human cancerQ37187016
PTEN and the PI3-kinase pathway in cancerQ37259680
Class I PI3K in oncogenic cellular transformation.Q37270450
APC shuttling to the membrane, nucleus and beyondQ37291638
Myc's broad reachQ37299032
LKB1; linking cell structure and tumor suppressionQ37333592
Lynch syndrome and related familial colorectal cancersQ37357249
Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR.Q37360712
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)479-507
P577publication date2011-01-01
P1433published inAnnual Review of Pathology: Mechanisms of DiseaseQ15263665
P1476titleMolecular genetics of colorectal cancer
Molecular Genetics of Colorectal Cancer
P478volume6

Reverse relations

cites work (P2860)
Q93018069(Pro)renin Receptor Expression Increases throughout the Colorectal Adenoma-Adenocarcinoma Sequence and It Is Associated with Worse Colorectal Cancer Prognosis
Q58548750A Bioinformatic Profile of Gene Expression of Colorectal Carcinoma Derived Organoids
Q60933442A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis
Q39002395A Prospective Study of Smoking and Risk of Synchronous Colorectal Cancers
Q57709818A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects
Q30561752A calibrated agent-based computer model of stochastic cell dynamics in normal human colon crypts useful for in silico experiments
Q37608528A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).
Q38912247A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells
Q37620700A functional role for Smad7 in sustaining colon cancer cell growth and survival.
Q37141208A gene browser of colorectal cancer with literature evidence and pre-computed regulatory information to identify key tumor suppressors and oncogenes
Q27852431A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.
Q36959154A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer
Q37017721A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC.
Q39787266A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1
Q34737151A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study
Q34455992A red meat-derived glycan promotes inflammation and cancer progression
Q35777548A survey of tandem repeat instabilities and associated gene expression changes in 35 colorectal cancers
Q64924502ANIMAL MODELS FOR COLORECTAL CANCER.
Q38041525APC and DNA Demethylation in Cell Fate Specification and Intestinal Cancer
Q39313634APC hypermethylation for early diagnosis of colorectal cancer: a meta-analysis and literature review
Q37209158APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation
Q30354461ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.
Q37056909Aberrant Promoter Methylation at CpG Cytosines Induce the Upregulation of the E2F5 Gene in Breast Cancer
Q55211165Aberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer.
Q38631444Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer
Q36391986Abnormal expression of GADD45B in human colorectal carcinoma
Q38760598Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States
Q38983986Activation of the PI3K/Akt/mTOR/p70S6K pathway is involved in S100A4-induced viability and migration in colorectal cancer cells
Q52625681Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile.
Q35761547Adiponectin Gene Polymorphisms are Associated with Increased Risk of Colorectal Cancer
Q40771944Advanced Proteogenomic Analysis Reveals Multiple Peptide Mutations and Complex Immunoglobulin Peptides in Colon Cancer
Q34671136Advanced colorectal adenoma related gene expression signature may predict prognostic for colorectal cancer patients with adenoma-carcinoma sequence.
Q45711137Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis
Q93226610Altered ARID1A expression in colorectal cancer
Q35677014Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APCMin/+ Mice
Q92135237Altered expression of renin-angiotensin system receptors throughout colorectal adenoma-adenocarcinoma sequence
Q35313181Altered pathways and colorectal cancer prognosis
Q40888327An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function
Q38619061An Optimal Mean Based Block Robust Feature Extraction Method to Identify Colorectal Cancer Genes with Integrated Data
Q92643926An enhanced genetic model of colorectal cancer progression history
Q91276869An immunohistochemical approach to detect oncogenic CTNNB1 mutations in primary neoplastic tissues
Q35882267An in vivo molecular response analysis of colorectal cancer treated with Astragalus membranaceus extract
Q85649650An updated meta-analysis of the association between GSTM1 polymorphism and colorectal cancer in Asians
Q55387488Analysis of potential genes and pathways associated with the colorectal normal mucosa-adenoma-carcinoma sequence.
Q27009170Animal models of colorectal cancer
Q54309791Annexin A10 is a marker for the serrated pathway of colorectal carcinoma
Q50284827Antagonistic Interactions between Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and Retinoic Acid Receptor Signaling in Colorectal Cancer Cells
Q35154305Apc and p53 interaction in DNA damage and genomic instability in hepatocytes
Q28315014Apoptotic effect of novel Schiff based CdCl₂(C₁₄H₂₁N₃O₂) complex is mediated via activation of the mitochondrial pathway in colon cancer cells
Q36086105Application of Circulating Tumor DNA as a Non-Invasive Tool for Monitoring the Progression of Colorectal Cancer
Q38015538Application of molecular techniques in the diagnosis, prognosis and management of patients with colorectal cancer: a practical approach
Q89221788Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
Q84445943Aqueous Fraction of Nephelium ramboutan-ake Rind Induces Mitochondrial-Mediated Apoptosis in HT-29 Human Colorectal Adenocarcinoma Cells
Q38730064Aspirin and colorectal cancer: the promise of precision chemoprevention.
Q44561607Assessment of the association between hOGG1 C8069G polymorphism and colorectal cancer
Q47916683Association between NQO1 C609T polymorphism and colorectal cancer risk
Q64083358Association between TP53 genetic polymorphisms and the methylation and expression of miR-34a, 34b/c in colorectal cancer tissues
Q35117711Association between appendectomy and subsequent colorectal cancer development: an Asian population study
Q40198390Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Q64064834Association of pathway mutation with survival after recurrence in colorectal cancer patients treated with adjuvant fluoropyrimidine and oxaliplatin chemotherapy
Q54979116Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer.
Q39123135B-cell epitope peptide vaccination targeting dimer interface of epidermal growth factor receptor (EGFR)
Q42353442BRAF inhibitor treatment of melanoma causing colonic polyps: An alternative hypothesis
Q37608879BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.
Q36675203Bcl-2 is a critical mediator of intestinal transformation
Q91754859Biomarker-guided therapy for colorectal cancer: strength in complexity
Q37597668Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer
Q88170682Butyrate Inhibits Indices of Colorectal Carcinogenesis via Enhancing α-Ketoglutarate-Dependent DNA Demethylation of Mismatch Repair Genes
Q38966986CDC42 inhibition suppresses progression of incipient intestinal tumors
Q37714068CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
Q38911627CP-31398 prevents the growth of p53-mutated colorectal cancer cells in vitro and in vivo
Q52643886CREPT facilitates colorectal cancer growth through inducing Wnt/β-catenin pathway by enhancing p300-mediated β-catenin acetylation
Q51025967CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls.
Q35756082Cancer Biology: A New RING to Wnt Signaling
Q36737189Cancer Stem Cells in Colorectal Cancer: Genetic and Epigenetic Changes
Q38050262Cancer syndromes and therapy by stop-codon readthrough
Q35034857Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice
Q36094119Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity
Q36920489Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance
Q35799783Capturing the Molecular and Biological Diversity of High-Grade Astrocytoma in Genetically Engineered Mouse Models
Q36916409Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis
Q91564745Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
Q28079969Changes in cellular mechanical properties during onset or progression of colorectal cancer
Q50195553Characterization of Cancer Stem Cells in Colon Adenocarcinoma Metastasis to the Liver
Q24318881Charting the molecular links between driver and susceptibility genes in colorectal cancer
Q34110442Checkpoint Signaling, Base Excision Repair, and PARP Promote Survival of Colon Cancer Cells Treated with 5-Fluorodeoxyuridine but Not 5-Fluorouracil
Q37109620Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis
Q38059925Chromothripsis: chromosomes in crisis
Q26801596Chronic inflammation and the development of malignancy in the GI tract
Q97587502CircAGFG1 drives metastasis and stemness in colorectal cancer by modulating YY1/CTNNB1
Q47630611Circadian gene hCLOCK contributes to progression of colorectal carcinoma and is directly regulated by tumor‑suppressive microRNA‑124.
Q35387747Circadian gene hClock enhances proliferation and inhibits apoptosis of human colorectal carcinoma cells in vitro and in vivo
Q35183062Clinical Response to Sorafenib in a Patient with Metastatic Colorectal Cancer and FLT3 Amplification
Q34378719Clinical application of genetics in management of colorectal cancer
Q37266384Clinical applications of next-generation sequencing in colorectal cancers
Q47682948Clinical performance evaluation of the Idylla NRAS-BRAF mutation test on retrospectively collected formalin-fixed paraffin-embedded colorectal cancer tissue
Q37086263Clinicopathologic distribution of KRAS and BRAF mutations in a Chinese population with colorectal cancer precursor lesions
Q33842013Co-occurrence of driver and passenger bacteria in human colorectal cancer
Q57100445Collaborating genomic, transcriptomic and microbiomic alterations lead to canine extreme intestinal polyposis
Q27853014Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab
Q52655145Colon cancers carrying BRAF V600E and β-catenin T41A activating mutations are resistant to numerous common anticancer drugs
Q38652194Colorectal Cancer Subtypes: Developmental Origin and Microenvironmental Regulation
Q57191694Colorectal cancer
Q36053988Colorectal cancer DNA methylation patterns from patients in Manaus, Brazil
Q37399066Colorectal cancer and the KIR genes in the human genome: A meta-analysis
Q34207776Colorectal cancer with liver metastases: neoadjuvant chemotherapy, surgical resection first or palliation alone?
Q55411157Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells.
Q34997425Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency
Q58737393Colorectal carcinogenesis: Insights into the cell death and signal transduction pathways: A review
Q35579056Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages
Q39036665Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas
Q58588233Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2
Q35135763Commensal bacteria drive endogenous transformation and tumour stem cell marker expression through a bystander effect
Q35990690Comparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia.
Q64970890Comparison of Microbiota in Patients Treated by Surgery or Chemotherapy by 16S rRNA Sequencing Reveals Potential Biomarkers for Colorectal Cancer Therapy.
Q41230971Comparison of biomarker expression between proximal and distal colorectal adenomas: The Tennessee-Indiana Adenoma Recurrence Study
Q92392618Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors
Q50966522Comparison of the performance of guaiac‐based and two immunochemical fecal occult blood tests for identifying advanced colorectal neoplasia in Taiwan
Q64253706Complex karyotype in myelodysplastic syndromes: Diagnostic procedure and prognostic susceptibility
Q61965595Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer
Q24630415Comprehensive molecular characterization of human colon and rectal cancer
Q89838002Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids
Q39066439Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer
Q35660195Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity
Q36027763Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling.
Q36292548Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform
Q41334598Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression
Q35643491Correlation between smoking history and molecular pathways in sporadic colorectal cancer: a meta-analysis.
Q36183202Correlation of NGX6 expression with clinicopathologic features and prognosis in colon cancer
Q37702124Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway
Q90158360Cost-effectiveness Evaluation of Targeted Surgical and Endoscopic Therapies for Early Colorectal Adenocarcinoma Based on Biomarker Profiles
Q43527311Cullin 4B is a novel prognostic marker that correlates with colon cancer progression and pathogenesis
Q58715258Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies
Q37697538Current and future molecular diagnostics in colorectal cancer and colorectal adenoma.
Q26747795Current status and perspectives in atomic force microscopy-based identification of cellular transformation
Q36210955DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer
Q37059820DNA Hypomethylation Contributes to Genomic Instability and Intestinal Cancer Initiation
Q54382592DNA content analysis of colorectal cancer defines a distinct 'microsatellite and chromosome stable' group but does not predict response to radiotherapy
Q30837199DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.
Q92017414DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways
Q31813071DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis
Q93007741Dancing from bottoms up - Roles of the POZ-ZF transcription factor Kaiso in Cancer
Q28083490Death-associated protein kinase: A molecule with functional antagonistic duality and a potential role in inflammatory bowel disease (Review)
Q35048299Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis
Q47164137Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer
Q38572102Deoxyribonucleotide metabolism, mutagenesis and cancer
Q40627933Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
Q39085740Determinants of metastatic competency in colorectal cancer
Q38049051Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch
Q59350458Diagnostic Potential and Interactive Dynamics of the Colorectal Cancer Virome
Q41618379Difference in expression of two neurokinin-1 receptors in adenoma and carcinoma from patients that underwent radical surgery for colorectal carcinoma
Q41378204Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors
Q37561628Differential expression of carbohydrate antigen 19-9 in human colorectal cancer: A comparison with colon and rectal cancers
Q36018367Dissecting characteristics and dynamics of differentially expressed proteins during multistage carcinogenesis of human colorectal cancer
Q35652713Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations
Q33699404Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells
Q33911191Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1
Q98386365Downregulation of microRNA-126 is inversely correlated with insulin receptor substrate-1 protein expression in colorectal cancer and is associated with advanced stages of disease
Q64269180Drug Sensitivity Screening and Targeted Pathway Analysis Reveal a Multi-Driver Proliferative Mechanism and Suggest a Strategy of Combination Targeted Therapy for Colorectal Cancer Cells
Q33613855Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer
Q37472937E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320a
Q37194925ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells
Q39345541Early detection: the impact of genomics
Q37288375Effect of API-1 and FR180204 on cell proliferation and apoptosis in human DLD-1 and LoVo colorectal cancer cells
Q35711107Effect of Maternal and Post-Weaning Folate Supply on Gene-Specific DNA Methylation in the Small Intestine of Weaning and Adult Apc+/Min and Wild Type Mice
Q92533188Effects of obesity and weight loss on mitochondrial structure and function and implications for colorectal cancer risk
Q34621479Efficient recovery of proteins from multiple source samples after TRIzol(®) or TRIzol(®)LS RNA extraction and long-term storage.
Q91838765Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin
Q26829126Emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer
Q51452289Endoluminal high-resolution MR imaging protocol for colon walls analysis in a mouse model of colitis
Q89619465Enterotoxigenic Bacteroides fragilis infection exacerbates tumorigenesis in AOM/DSS mouse model
Q28084849Epigenetic regulation of the intestinal epithelium
Q22252606Epigenetics Offer New Horizons for Colorectal Cancer Prevention
Q36081553Epigenetics and colorectal cancer
Q37061792Epigenetics and colorectal cancer pathogenesis
Q40357382Epigenomic landscape of 5-hydroxymethylcytosine reveals its transcriptional regulation of lncRNAs in colorectal cancer.
Q39107166Epithelial Hypoxia-Inducible Factor 2α Facilitates the Progression of Colon Tumors through Recruiting Neutrophils
Q90129976Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
Q38763748Epithelial-to-mesenchymal transition transcription factors in cancer-associated fibroblasts
Q34704942Establishment of genetically diverse patient-derived xenografts of colorectal cancer.
Q91618178Evaluation of colorectal cancer subtypes and cell lines using deep learning
Q46016448Evolution of genetic instability in heterogeneous tumors.
Q37702251Evolutionary biologic changes of gut microbiota in an 'adenoma-carcinoma sequence' mouse colorectal cancer model induced by 1, 2-Dimethylhydrazine
Q36097337Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways
Q38683093Expending Role of Microsatellite Instability in Diagnosis and Treatment of Colorectal Cancers.
Q97539272Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges
Q23911034Exposure to carbon nanotubes leads to changes in the cellular biomechanics
Q37192986Expression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer.
Q37712679Expression Status of UBE2Q2 in Colorectal Primary Tumors and Cell Lines
Q64885531Expression and Localization of Cathepsins B, D and G in Cancer Stem Cells in Liver Metastasis From Colon Adenocarcinoma.
Q37106692Expression of MCRS1 and MCRS2 and their correlation with serum carcinoembryonic antigen in colorectal cancer
Q36297343Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF.
Q39662667Expression of mitochondrial genes MT-ND1, MT-ND6, MT-CYB, MT-COI, MT-ATP6, and 12S/MT-RNR1 in colorectal adenopolyps.
Q36321648Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma.
Q92713830FGF14 Functions as a Tumor Suppressor through Inhibiting PI3K/AKT/mTOR Pathway in Colorectal Cancer
Q38205339Familial colorectal cancer type X: genetic profiles and phenotypic features.
Q89766936Fecal Metabolomic Signatures in Colorectal Adenoma Patients Are Associated with Gut Microbiota and Early Events of Colorectal Cancer Pathogenesis
Q90208541Feedback analysis identifies a combination target for overcoming adaptive resistance to targeted cancer therapy
Q92127401Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence
Q38232753Focus on genetic and epigenetic events of colorectal cancer pathogenesis: implications for molecular diagnosis
Q38831347Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer
Q34372544Forced Expression of miR-143 Represses ERK5/c-Myc and p68/p72 Signaling in Concert with miR-145 in Gut Tumors of ApcMin Mice
Q34515894Frequent alteration of the tumor suppressor gene APC in sporadic canine colorectal tumors
Q50199383From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells
Q38786707From tumour heterogeneity to advances in precision treatment of colorectal cancer
Q43241085Functional and protein‑protein interaction network analysis of colorectal cancer induced by ulcerative colitis
Q34357186Functional annotation of colon cancer risk SNPs
Q92971616Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas
Q35273347Functional repair of p53 mutation in colorectal cancer cells using trans-splicing
Q50026061Functional significance and therapeutic implication of ring-type E3 ligases in colorectal cancer
Q36292186GSTM1 polymorphism contribute to colorectal cancer in Asian populations: a prospective meta-analysis
Q37384881Gamma-tocopherol attenuates moderate but not severe colitis and suppresses moderate colitis-promoted colon tumorigenesis in mice
Q37716976Gastrointestinal malignancy and the microbiome.
Q94322174Gene Expression Analysis of Sporadic Early-Onset Rectal Adenocarcinoma
Q47099108Gene expression profile comparison between colorectal cancer and adjacent normal tissues
Q42775534Gene-Diet Interactions on Colorectal Cancer Risk
Q37369513Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research
Q37230991Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine
Q35815688Genetic Manipulation of Homologous Recombination In Vivo Attenuates Intestinal Tumorigenesis
Q35091509Genetic analysis of colon tumors induced by a dietary carcinogen PhIP in CYP1A humanized mice: Identification of mutation of β-catenin/Ctnnb1 as the driver gene for the carcinogenesis
Q35989027Genetic and Diet-Induced Obesity Increased Intestinal Tumorigenesis in the Double Mutant Mouse Model Multiple Intestinal Neoplasia X Obese via Disturbed Glucose Regulation and Inflammation
Q37730129Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids
Q40228878Genetic heterogeneity in synchronous colorectal cancers impacts genotyping approaches and therapeutic strategies
Q34832690Genetic pathways, prevention, and treatment of sporadic colorectal cancer
Q38191462Genetic unraveling of colorectal cancer
Q92662598Genetically Engineered Pigs to Study Cancer
Q50107614Genetically engineered pigs as models for human disease
Q28084346Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer
Q28082721Genetics of colorectal cancer
Q37445217Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips.
Q53228400Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X.
Q37326689Genome-wide multi-omics profiling of colorectal cancer identifies immune determinants strongly associated with relapse
Q37087002Genomic Landscape of Colorectal Mucosa and Adenomas
Q64963172Genomic clustering of fitness-affecting mutations favors the evolution of chromosomal instability.
Q34657586Genomic era diagnosis and management of hereditary and sporadic colon cancer.
Q34560110Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated rat.
Q37687487Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients
Q38074617Genomics and epigenomics of colorectal cancer
Q39967039Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology
Q36677253Get the Fat Out!
Q37699199Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling
Q39395261Global methylation profiling to identify epigenetic signature of gallbladder cancer and gallstone disease.
Q43878989Glutathione S-transferase M1 polymorphism and colorectal cancer risk in Chinese population
Q57980063Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer
Q39120155Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer
Q28074181Guanylyl cyclase C signaling axis and colon cancer prevention
Q26775402Gut Microbiota and Colorectal Cancer
Q35172970Gut microbiome and colorectal adenomas
Q92358237Gut microbiome associated with APC gene mutation in patients with intestinal adenomatous polyps
Q91641742Gut microbiome identifies risk for colorectal polyps
Q37584313HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker
Q30847630HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche
Q34140330HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells
Q37447969High FOXRED1 expression predicted good prognosis of colorectal cancer
Q36694384High expression of Fatty Acid-Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells
Q36184195High-Throughput Screening Strategies for Targeted Identification of Therapeutic Compounds in Colorectal Cancer
Q42720297High-throughput sequencing to identify miRNA biomarkers in colorectal cancer patients
Q36717750Highly sensitive, non-invasive detection of colorectal cancer mutations using single molecule, third generation sequencing
Q47927828Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis
Q50850992Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model
Q41678975Hypoxia-inducible factors: a central link between inflammation and cancer
Q34603915ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability
Q50041873IKKα is required in the intestinal epithelial cells for tumour stemness.
Q53236646IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells
Q35993139ITF-2B protein levels are correlated with favorable prognosis in patients with colorectal carcinomas.
Q34354515Identification of 33 candidate oncogenes by screening for base-specific mutations.
Q36121608Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis.
Q55027358Identification of copy number alterations in colon cancer from analysis of amplicon-based next generation sequencing data.
Q55002474Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.
Q92154743Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis
Q44032588Identification of hub genes, key miRNAs and potential molecular mechanisms of colorectal cancer
Q34977426Identification of novel mutations by exome sequencing in African American colorectal cancer patients
Q53827639Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome.
Q36492931Immunohistochemistry and microsatellite instability analysis in molecular subtyping of colorectal carcinoma based on mismatch repair competency
Q84238463Immunostaining in the context of loss mismatch repair function: interpretive confounders and cautionary tales!
Q90113851Immunotherapy, Inflammation and Colorectal Cancer
Q64105079Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development
Q35037258Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer.
Q36934236In vitro organoid culture of primary mouse colon tumors
Q35007556In vivo molecular mapping of the tumor microenvironment in an azoxymethane-treated mouse model of colon carcinogenesis
Q39188239In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion.
Q39162939Inactivation of TGF-β signaling and loss of PTEN cooperate to induce colon cancer in vivo
Q64891149Increased EZH2 expression during the adenoma-carcinoma sequence in colorectal cancer.
Q49925787Increased colon cancer risk after severe Salmonella infection
Q36761921Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer
Q38860405Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers.
Q92632779Infection with genotoxin-producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in colonic epithelial cells
Q60511100Inflammation and Colorectal Cancer
Q42094255Influence of miRNA-106b and miRNA-135a on butyrate-regulated expression of p21 and Cyclin D2 in human colon adenoma cells
Q41612495Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice
Q30276647Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter
Q35561695Integrating contextual miRNA and protein signatures for diagnostic and treatment decisions in cancer
Q92361660Integrative Gene Expression Profiling Analysis to Investigate Potential Prognostic Biomarkers for Colorectal Cancer
Q93081119Intercellular Transfer of Oncogenic KRAS via Tunneling Nanotubes Introduces Intracellular Mutational Heterogeneity in Colon Cancer Cells
Q36065268Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis
Q59351894Interleukin-33 and ST2 Signaling in Tumor Microenvironment
Q34989590Interplay between DNA repair and inflammation, and the link to cancer
Q37083757Intestinal Iron Homeostasis and Colon Tumorigenesis
Q39365117Intestinal carcinogenesis: IKK can go all the way.
Q57169731Intestinal microbiota: a novel perspective in colorectal cancer biotherapeutics
Q24307391Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
Q39139446Intra-tumor heterogeneity from a cancer stem cell perspective.
Q58053534Intrinsic cancer subtypes-next steps into personalized medicine
Q34995814Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of β-catenin/TCF transcription
Q38949705Iro/IRX transcription factors negatively regulate Dpp/TGF-β pathway activity during intestinal tumorigenesis
Q38708005K-ras Mutations as the Earliest Driving Force in a Subset of Colorectal Carcinomas
Q38765961KSR1 and EPHB4 Regulate Myc and PGC1β To Promote Survival of Human Colon Tumors
Q43481817Knockdown of HOXA-AS2 suppresses proliferation and induces apoptosis in colorectal cancer
Q35635465LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans
Q36414307LINE-1 hypomethylation in normal colon mucosa is associated with poor survival in Chinese patients with sporadic colon cancer.
Q37363897LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer
Q30316110LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner
Q34371544LSF expression and its prognostic implication in colorectal cancer
Q37282490Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases
Q38940251Lhx3 is required to maintain cancer cell development of high-grade oligodendroglioma
Q36991078Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.
Q35698851Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model
Q35247201Lithium chloride induces mesenchymal‑to‑epithelial reverting transition in primary colon cancer cell cultures.
Q47729757Logarithmic expansion of LGR5+ cells in human colorectal cancer.
Q89495845Long non-coding RNA LINC00707 acts as a competing endogenous RNA to enhance cell proliferation in colorectal cancer
Q42314709Long non-coding RNA SPRY4-IT1 pormotes colorectal cancer metastasis by regulate epithelial-mesenchymal transition
Q37706687Long non-coding RNA growth arrest specific transcript 5 acts as a tumour suppressor in colorectal cancer by inhibiting interleukin-10 and vascular endothelial growth factor expression
Q47138075Long non-coding RNAs in Colorectal Cancer: Progression and Future Directions
Q64235041Long noncoding RNA GIHCG induces cancer progression and chemoresistance and indicates poor prognosis in colorectal cancer
Q47106149Long noncoding RNA XIST is a prognostic factor in colorectal cancer and inhibits 5-fluorouracil-induced cell cytotoxicity through promoting thymidylate synthase expression
Q55424846Long noncoding RNA lnc-sox5 modulates CRC tumorigenesis by unbalancing tumor microenvironment.
Q36170646Long-Range Signaling in MutS and MSH Homologs via Switching of Dynamic Communication Pathways
Q40492521Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways.
Q42136714Loss of HLTF function promotes intestinal carcinogenesis
Q35959727Loss of Heterozygosity at the Glutathione Peroxidase 1 Locus Is Not an Early Event in Colon Carcinogenesis
Q86924304Loss of NF2/Merlin expression in advanced sporadic colorectal cancer
Q42718487Loss of the polycomb mark from bivalent promoters leads to activation of cancer-promoting genes in colorectal tumors
Q64245050MEK Inhibition Induces Canonical WNT Signaling through YAP in Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Q36447499ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer
Q35931767MUC1-C activates the TAK1 inflammatory pathway in colon cancer
Q37164549MUC4 is negatively regulated through the Wnt/β-catenin pathway via the Notch effector Hath1 in colorectal cancer
Q35758028MYBL2 is an independent prognostic marker that has tumor-promoting functions in colorectal cancer.
Q26740310Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer
Q64118815Marine omega-3 fatty acid intake and survival of stage III colon cancer according to tumor molecular markers in NCCTG Phase III trial N0147 (Alliance)
Q56530637Matrix metalloproteinase 9 expression and prognosis in colorectal cancer: a meta-analysis
Q64955692Mechanism of Apoptosis Induced by Curcumin in Colorectal Cancer.
Q35145340Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression
Q35006439Meta-analysis of the association between APC promoter methylation and colorectal cancer
Q90633229Metaproteomics characterizes human gut microbiome function in colorectal cancer
Q37495759Metformin: a potential therapeutic agent for recurrent colon cancer
Q55072444Methylation and Gene Expression of BCAT1 and IKZF1 in Colorectal Cancer Tissues.
Q35871204Methylation of Werner syndrome protein is associated with the occurrence and development of invasive meningioma via the regulation of Myc and p53 expression
Q90062154MicroRNA Biogenesis Pathway Genes Are Deregulated in Colorectal Cancer
Q34538870MicroRNA Methylation in Colorectal Cancer
Q42398055MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer
Q36901851MicroRNA polymorphisms and risk of colorectal cancer
Q34282551MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer
Q38774242MicroRNA-92a Promotes Colorectal Cancer Cell Growth and Migration by Inhibiting KLF4.
Q90292677Microbiota Profile and Impact of Fusobacterium nucleatum in Colorectal Cancer Patients of Barretos Cancer Hospital
Q27028132Microbiota impact on the epigenetic regulation of colorectal cancer
Q42281581Micromanaging the classification of colon cancer: the role of the microRNAome.
Q37269648Microsatellite instability and loss of heterozygosity detected in middle-aged patients with sporadic colon cancer: A retrospective study.
Q30378082Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
Q51116841Mismatch repair deficient-crypts in non-neoplastic colonic mucosa in Lynch syndrome: insights from an illustrative case
Q84301243Missense Mutations in MLH1, MSH2, KRAS, and APC Genes in Colorectal Cancer Patients in Malaysia
Q55206405Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer.
Q52423411Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids
Q43212807Modelling the evolution of genetic instability during tumour progression
Q41037621Molecular Characterization of Somatic Alterations in Dukes' B and C Colorectal Cancers by Targeted Sequencing
Q38947671Molecular Diagnostic Applications in Colorectal Cancer.
Q36836733Molecular Dissection of Microsatellite Instable Colorectal Cancer
Q35977849Molecular Events in Primary and Metastatic Colorectal Carcinoma: A Review
Q26747329Molecular Subtypes and Personalized Therapy in Metastatic Colorectal Cancer
Q49912428Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations
Q39238579Molecular endoscopy for targeted imaging in the digestive tract
Q37585385Molecular markers of carcinogenesis for risk stratification of individuals with colorectal polyps: a case-control study
Q36159222Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis
Q38211357Molecular mechanisms of oncogene-induced inflammation and inflammation-sustained oncogene activation in gastrointestinal tumors: an under-appreciated symbiotic relationship
Q36545430Molecular pathological epidemiology of colorectal cancer in Chinese patients with KRAS and BRAF mutations
Q38953543Molecular pathways driving disease-specific alterations of intestinal epithelial cells
Q41091941Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience
Q39235977Molecular subtypes in cancers of the gastrointestinal tract
Q42425332Molecular subtyping of colorectal cancer: time to explore both intertumoral and intratumoral heterogeneity to evaluate patient outcome
Q26774627Mouse models for the discovery of colorectal cancer driver genes
Q27008537Mouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studies
Q28081871Mouse models of colorectal cancer as preclinical models
Q26785563Mouse models of intestinal cancer
Q37238133Mucins and Wnt/β-catenin signaling in gastrointestinal cancers: an unholy nexus
Q35871650Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers
Q34434094MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes.
Q28547426Multidrug Resistance-Associated Protein 2 Expression Is Upregulated by Adenosine 5'-Triphosphate in Colorectal Cancer Cells and Enhances Their Survival to Chemotherapeutic Drugs
Q36541309Multispectral Endoscopic Imaging of Colorectal Dysplasia In Vivo
Q100633769Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation
Q93367358Mutant p53 in colon cancer
Q36852678Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.
Q89550768Mutation Analysis of Colorectal and Gastric Carcinomas Originating from Adenomas: Insights into Genomic Evolution Associated with Malignant Progression
Q36526325Mutation analysis of 13 driver genes of colorectal cancer-related pathways in Taiwanese patients
Q34619293Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy
Q37969849Mutations and epimutations in the origin of cancer
Q34982562Mutations in POLE and survival of colorectal cancer patients--link to disease stage and treatment
Q33905741Mutations of C-reactive protein (CRP) -286 SNP, APC and p53 in colorectal cancer: implication for a CRP-Wnt crosstalk
Q37225530Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients
Q35574969Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein
Q50575449NOD2 Genetic Variants Predispose One of Two Familial Adenomatous Polyposis Siblings to Pouchitis Through Microbiome Dysbiosis
Q41342397NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations.
Q37247510Nanoproteomic analysis of extracellular receptor kinase-1/2 post-translational activation in microdissected human hyperplastic colon lesions
Q52579667Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.
Q90503326Neutrophils Restrict Tumor-Associated Microbiota to Reduce Growth and Invasion of Colon Tumors in Mice
Q33731804New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets
Q53283058Non-serrated precursor lesions of colorectal tumours
Q33600442Notch as a Driver of Gastric Epithelial Cell Proliferation
Q36562344Novel insights into Notum and glypicans regulation in colorectal cancer
Q52640415Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors.
Q37085942Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/β-catenin signaling
Q37074078Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.
Q37854803Obesity‐related colon cancer: Dietary factors and their mechanisms of anticancer action‡
Q37325202Olfactomedin 4 deletion induces colon adenocarcinoma in Apc(Min/+) mice
Q34459046Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer
Q27003364On the apparent rarity of epithelial cancers in captive chimpanzees
Q33694667Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β
Q44943773Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids.
Q50648214Oncogenicity of LHX4 in colorectal cancer through Wnt/β-catenin/TCF4 cascade
Q33765195Optimization of a pentaplex panel for MSI analysis without control DNA in a Brazilian population: correlation with ancestry markers.
Q48120325Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract
Q99636824Organoid Models of Colorectal Pathology: Do They Hold the Key to Personalized Medicine? A Systematic Review
Q35649789Ovarian stem cells: From basic to clinical applications
Q51383263Ovarian steroid cell tumor with biallelic adenomatous polyposis coli inactivation in a patient with familial adenomatous polyposis.
Q61632631Overcoming Drug Resistance in Colorectal Cancer by MicroRNAs
Q51118852Overexpression of Hepatocyte Cell Adhesion Molecule (hepaCAM) Inhibits the Proliferation, Migration, and Invasion in Colorectal Cancer Cells
Q51650705Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies
Q35173907P53 mutations occur more commonly than KRAS mutations in colorectal adenoma
Q37745350PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407.
Q41709327PPA1 regulates tumor malignant potential and clinical outcome of colon adenocarcinoma through JNK pathways
Q36546764PRIMA-1met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms
Q36621295PS341 inhibits hepatocellular and colorectal cancer cells through the FOXO3/CTNNB1 signaling pathway
Q55344912PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation.
Q34786561Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer
Q43696219Pathogenesis of microsatellite-unstable colorectal cancer. Evaluation of new diagnostic and therapeutic options
Q26991908Personalised cancer medicine
Q38363276Personalized treatment for colorectal cancer: novel developments and putative therapeutic strategies
Q37962026Pharmacology and cellular/molecular mechanisms of action of aspirin and Non-aspirin NSAIDs in colorectal cancer
Q35721747Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-κB Pathway
Q49787846Phospholipase Cγ1 links inflammation and tumorigenesis in colitis-associated cancer
Q42376377Pien Tze Huang inhibits the proliferation of colorectal cancer cells by increasing the expression of miR-34c-5p
Q37548804Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study
Q37513254Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer
Q36363009Powerful Set-Based Gene-Environment Interaction Testing Framework for Complex Diseases
Q35800325Precritical State Transition Dynamics in the Attractor Landscape of a Molecular Interaction Network Underlying Colorectal Tumorigenesis
Q93198699Prevalence and characteristics of PIK3CA mutation in mismatch repair-deficient colorectal cancer
Q84058811Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study
Q33754774Prevention of Colorectal Cancer by Targeting Obesity-Related Disorders and Inflammation
Q37630186Proactive strategies for regorafenib in metastatic colorectal cancer: implications for optimal patient management.
Q33659798Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series
Q35138892Promoter hypermethylation of tumour suppressor genes as potential biomarkers in colorectal cancer
Q34762217Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence.
Q38877277Prospective derivation of a living organoid biobank of colorectal cancer patients.
Q36579336Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis
Q30414232Prostate cancer induced by loss of Apc is restrained by TGFβ signaling
Q28244320Proteogenomic characterization of human colon and rectal cancer
Q39439499Proteomic consequences of a single gene mutation in a colorectal cancer model
Q34454877Proteomic workflow for analysis of archival formalin‐fixed and paraffin‐embedded clinical samples to a depth of 10 000 proteins
Q47340368Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and are Primed for Neoplastic Progression
Q46266548Pteisolic acid G, a novel ent-kaurane diterpenoid, inhibits viability and induces apoptosis in human colorectal carcinoma cells
Q35859573Quantitative Profiling of Protein Tyrosine Kinases in Human Cancer Cell Lines by Multiplexed Parallel Reaction Monitoring Assays
Q38116869RAS signaling pathways, mutations and their role in colorectal cancer
Q125637295RETRACTED ARTICLE: Long non-coding RNA DCST1-AS1/hsa-miR-582-5p/HMGB1 axis regulates colorectal cancer progression
Q37566592RNA virus receptor Rig-I monitors gut microbiota and inhibits colitis-associated colorectal cancer
Q38630685RNF183 promotes proliferation and metastasis of colorectal cancer cells via activation of NF-κB-IL-8 axis
Q37113219ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration
Q28396460ROS, Notch, and Wnt signaling pathways: crosstalk between three major regulators of cardiovascular biology
Q47156095RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis
Q28075465Racial disparity in colorectal cancer: Gut microbiome and cancer stem cells
Q38764759Rad51C-ATXN7 fusion gene expression in colorectal tumors
Q54517954Ras Stabilization Through Aberrant Activation of Wnt/β-Catenin Signaling Promotes Intestinal Tumorigenesis
Q52721338Ras and Rap1: A tale of two GTPases.
Q35052477Real-time imaging of myeloid cells dynamics in ApcMin/+ intestinal tumors by spinning disk confocal microscopy
Q36949683Recurrent R-spondin fusions in colon cancer
Q37972816Red meat consumption and cancer: Reasons to suspect involvement of bovine infectious factors in colorectal cancer
Q91705167Reduced microRNA 375 in colorectal cancer upregulates metadherin-mediated signaling
Q28603875Registered report: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
Q90225694Regulation of Ketogenic Enzyme HMGCS2 by Wnt/β-catenin/PPARγ Pathway in Intestinal Cells
Q85739124Regulation of MLH1 mRNA and protein expression by promoter methylation in primary colorectal cancer: a descriptive and prognostic cancer marker study
Q26775423Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer
Q36860267Regulation of Wnt4 in chronic obstructive pulmonary disease
Q36418722Relationship between Preoperative ¹⁸F-Fluorodeoxyglucose Uptake and Epidermal Growth Factor Receptor Status in Primary Colorectal Cancer.
Q34463139Republished: tracing PAKs from GI inflammation to cancer
Q39191677Retracted: Role of STAT3 and vitamin D receptor in EZH2‐mediated invasion of human colorectal cancer
Q93161855Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
Q48208216Reversal of hyperactive Wnt signaling-dependent adipocyte defects by peptide boronic acids.
Q93066429Reviewing the role of P2Y receptors in specific gastrointestinal cancers
Q91949803Right and left-sided colon cancers - specificity of molecular mechanisms in tumorigenesis and progression
Q49237718Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids
Q37313245Role of S100A3 in human colorectal cancer and the anticancer effect of cantharidinate
Q58128147Role of curcumin in preventing familial adenomatous polyposis
Q37267725SEPT9 and SHOX2 DNA methylation status and its utility in the diagnosis of colonic adenomas and colorectal adenocarcinomas
Q39211407SLIT2 inhibits cell migration in colorectal cancer through the AKT–GSK3β signaling pathway
Q34486808Screening of Finnish RAD51C founder mutations in prostate and colorectal cancer patients
Q35169992Secernin-1 contributes to colon cancer progression through enhancing matrix metalloproteinase-2/9 exocytosis
Q64101631Selected Aspects of Chemoresistance Mechanisms in Colorectal Carcinoma-A Focus on Epithelial-to-Mesenchymal Transition, Autophagy, and Apoptosis
Q52423597Sequential cancer mutations in cultured human intestinal stem cells
Q26751035Serrated colorectal cancer: Molecular classification, prognosis, and response to chemotherapy
Q27010553Serrated pathway in colorectal carcinogenesis
Q28264306Signal Transducer and Activator of Transcription 3 (STAT3) Protein Suppresses Adenoma-to-carcinoma Transition in Apc/+ Mice via Regulation of Snail-1 (SNAI) Protein Stability
Q101133262Signal transduction pathway mutations in gastrointestinal (GI) cancers: a systematic review and meta-analysis
Q91897235Signaling pathways involved in colorectal cancer progression
Q26795609Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance
Q30912170Simultaneous inference of cancer pathways and tumor progression from cross-sectional mutation data
Q61807849Sine oculis homeobox 1 promotes proliferation and migration of human colorectal cancer cells through activation of Wnt/β-catenin signaling
Q31133433Single-cell SNP analyses and interpretations based on RNA-Seq data for colon cancer research
Q37955579Sleeping Beauty – A mouse model for all cancers?
Q91742165Smad7 and Colorectal Carcinogenesis: A Double-Edged Sword
Q33878967Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
Q36050149Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation
Q52336141Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.
Q36580560Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability
Q37062872Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation
Q33581581Specific microRNA-mRNA Regulatory Network of Colon Cancer Invasion Mediated by Tissue Kallikrein-Related Peptidase 6.
Q39139086Specific mutations in KRAS codon 12 are associated with worse overall survival in patients with advanced and recurrent colorectal cancer
Q61796403Sphere‑forming assay vs. organoid culture: Determining long‑term stemness and the chemoresistant capacity of primary colorectal cancer cells
Q55212706Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.
Q28076017Stem cell dynamics and pretumor progression in the intestinal tract
Q38219625Stem cell dynamics in homeostasis and cancer of the intestine
Q55667339Stepwise approach to SNP-set analysis illustrated with the Metabochip and colorectal cancer in Japanese Americans of the Multiethnic Cohort.
Q34396677Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice
Q34526671Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines
Q53615706Surgical treatment of multiple sporadic colorectal carcinoma
Q27013718Survivin and angiotensin-converting enzyme polymorphisms with risk of colorectal cancer: a systematic review and meta-analysis
Q90352739Synaptotagmin7 Is Overexpressed In Colorectal Cancer And Regulates Colorectal Cancer Cell Proliferation
Q60937768Synthetic Cannabinoid Activity Against Colorectal Cancer Cells
Q40114381Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance to trametinib in colorectal cancer cells
Q101574338Synthetic lethality between MyD88 loss and mutations in Wnt/β-catenin pathway in intestinal tumor epithelial cells
Q35059602Systematic genomic identification of colorectal cancer genes delineating advanced from early clinical stage and metastasis
Q35763436Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.
Q37702574T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice
Q88702138TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells
Q92807356TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells
Q92835171Targeted molecular profiling of genetic alterations in colorectal cancer using next-generation sequencing
Q28655517Targeted repression of AXIN2 and MYC gene expression using designer TALEs
Q34735416Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing
Q36646911Targeted therapies in colorectal cancer—an integrative view by PPPM
Q39441327Targeting TGF-β Signaling in Cancer
Q90020207Targeting Wnt Signaling via Notch in Intestinal Carcinogenesis
Q38569786Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms
Q27027266Targeting aberrant colon cancer-specific DNA methylation with lipoteichoic acid-deficient Lactobacillus acidophilus
Q36356078Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3
Q42357549Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage
Q39456735Targeting the Microenvironment in Advanced Colorectal Cancer
Q42133560Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy.
Q55260595Teaming Up for Trouble: Cancer Cells, Transforming Growth Factor-β1 Signaling and the Epigenetic Corruption of Stromal Naïve Fibroblasts.
Q51598791Tescalcin expression contributes to invasive and metastatic activity in colorectal cancer
Q52571294Testing for NRAS Mutations in Serous Borderline Ovarian Tumors and Low-Grade Serous Ovarian Carcinomas.
Q95642199The Bacterial Microbiota of Gastrointestinal Cancers: Role in Cancer Pathogenesis and Therapeutic Perspectives
Q37908119The Causes and Consequences of Polyploidy in Normal Development and Cancer
Q39133310The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology
Q41991370The ESRP1-GPR137 axis contributes to intestinal pathogenesis.
Q58798789The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia
Q36597522The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice
Q92971247The Intestinal Stem Cell Niche: A Central Role for Foxl1-Expressing Subepithelial Telocytes
Q36937205The MYC 3' Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells
Q33823452The NF1 somatic mutational landscape in sporadic human cancers
Q92264981The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo
Q54276735The Proto-Oncogene KRAS and BRAF Profiles and Some Clinical Characteristics in Colorectal Cancer in the Turkish Population
Q37571181The Role of IL-33-Dependent Inflammation in the Tumor Microenvironment.
Q32183705The Role of Somatic L1 Retrotransposition in Human Cancers
Q38893314The Role of Stem Cell DNA Methylation in Colorectal Carcinogenesis
Q26741388The Role of the C-Clamp in Wnt-Related Colorectal Cancers
Q30437998The Theranostic Path to Personalized Nanomedicine
Q37116458The attitudes of people with sarcoma and their family towards genomics and incidental information arising from genetic research
Q44619316The burden of faulty proofreading in colon cancer
Q37699177The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A.
Q90259673The controversial role of Enterococcus faecalis in colorectal cancer
Q52665387The cytotoxic, apoptotic and oxidative effects of carbonic anhydrase IX inhibitor on colorectal cancer cells.
Q33905852The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells
Q21090644The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer
Q28077234The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery
Q64275763The histone H3 lysine-27 demethylase UTX plays a critical role in colorectal cancer cell proliferation
Q47634731The human PKP2/plakophilin-2 gene is induced by Wnt/β-catenin in normal and colon cancer-associated fibroblasts
Q34457985The human gut microbiome as a screening tool for colorectal cancer.
Q47418712The impact of primary tumor location in patients with metastatic colorectal cancer: a Korean Cancer Study Group CO12-04 study
Q90003187The influence of blood on the human gut microbiome
Q35249997The intrauterine and nursing period is a window of susceptibility for development of obesity and intestinal tumorigenesis by a high fat diet in Min/+ mice as adults
Q37713641The myc 3' wnt-responsive element suppresses colonic tumorigenesis
Q54297427The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer
Q28071309Therapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseases
Q36036531Time-serial Assessment of Drug Combination Interventions in a Mouse Model of Colorectal Carcinogenesis Using Optical Coherence Tomography
Q92462964Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
Q35830331Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium
Q40555695Tissue-specific mutation accumulation in human adult stem cells during life
Q37445275Toward a comprehensive and systematic methylome signature in colorectal cancers
Q38113960Towards a vaccine to prevent cancer in Lynch syndrome patients
Q38041096Transcriptional networks in liver and intestinal development
Q50642659Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity
Q42530938Transition from colitis to cancer: high Wnt activity sustains the tumor-initiating potential of colon cancer stem cell precursors
Q33722761Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis
Q26776215Treatment Individualization in Colorectal Cancer
Q92427915Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis
Q36723450Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.
Q39194701Tumor suppressor genes in familial adenomatous polyposis
Q46238868Tumor-derived exosomes in colorectal cancer progression and their clinical applications
Q36757322Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1
Q92130522Uncovering Potential Therapeutic Targets in Colorectal Cancer by Deciphering Mutational Status and Expression of Druggable Oncogenes
Q39090006Up-regulation of tripartite motif-containing 29 promotes cancer cell proliferation and predicts poor survival in colorectal cancer
Q54979868Update on Sporadic Colorectal Cancer Genetics.
Q58697697Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor in colon cancer cells
Q33758617Vitamin D/VDR, Probiotics, and Gastrointestinal Diseases
Q35600360Volatility of Mutator Phenotypes at Single Cell Resolution
Q37701641Whole-exome sequencing identified mutational profiles of high-grade colon adenomas
Q33791204Wiring miRNAs to pathways: a topological approach to integrate miRNA and mRNA expression profiles
Q26746101Wnt Signaling in Cancer Stem Cell Biology
Q40191438Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells.
Q42321100Wnt signalling is a bi-directional vulnerability of cancer cells
Q42034441YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis
Q35674089cir-ITCH plays an inhibitory role in colorectal cancer by regulating the Wnt/β-catenin pathway
Q35616117dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants
Q52945589miR-107 Promotes Proliferation and Inhibits Apoptosis of Colon Cancer Cells by Targeting Prostate Apoptosis Response-4 (Par4).
Q45839379miR-187 inhibits the growth of cervical cancer cells by targeting FGF9.
Q36837231miR-23a promotes the transition from indolent to invasive colorectal cancer
Q47148750miR-449a inhibits colorectal cancer progression by targeting SATB2.
Q41701952miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma
Q98652622α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer
Q49547317β-Catenin mRNA Silencing and MEK Inhibition Display Synergistic Efficacy in Preclinical Tumor Models
Q91746684β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells
Q49750144β-catenin, leucine-rich repeat-containing G protein-coupled receptor 5 and GATA-binding factor 6 are associated with the normal mucosa-adenoma-adenocarcinoma sequence of colorectal tumorigenesis

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