Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression

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Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression is …
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scholarly articleQ13442814

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P356DOI10.3748/WJG.V23.I29.5266
P932PMC publication ID5550776
P698PubMed publication ID28839427

P2093author name stringMaría F Troncoso
María L Bacigalupo
Pablo Carabias
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Tumor cells secrete galectin-1 to enhance endothelial cell activity.Q44132717
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Overexpression of galectin-3 enhances migration of colon cancer cells related to activation of the K-Ras–Raf–Erk1/2 pathwayQ53143098
Galectin-1 Controls the Proliferation and Migration of Liver Sinusoidal Endothelial Cells and Their Interaction With Hepatocarcinoma CellsQ53284113
An application of the 2‐nitrobenzenesulfenyl method to proteomic profiling of human colorectal carcinoma: A novel approach for biomarker discoveryQ53474321
Apoptosis and anergy of T cell induced by pancreatic stellate cells-derived galectin-1 in pancreatic cancerQ53600526
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Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancerQ55055061
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Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancerQ73644483
Expression of N-acetylglucosaminyltransferase V in colorectal cancer correlates with metastasis and poor prognosisQ73803378
Differential expression of galectin 3 and galectin 1 in colorectal cancer progressionQ73933595
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Galectin-1 and galectin-3 in chronic pancreatitisQ74194859
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Acinar‐to‐ductal metaplasia accompanies c‐myc‐induced exocrine pancreatic cancer progression in transgenic rodentsQ82181907
Molecular Genetics of Colorectal CancerQ82521439
CD24 and galectin-1 expressions in gastric adenocarcinoma and clinicopathologic significanceQ83005419
Overexpression of galectin-1 is associated with poor prognosis in human hepatocellular carcinoma following resectionQ83701996
Gemcitabine in the chemoradiotherapy for locally advanced pancreatic cancer: a meta-analysisQ84100587
High expression of Galectin‐1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancerQ84584414
Pancreatic cancerQ87198210
Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesionsQ34244725
Galectins as modulators of tumour progressionQ34381235
Indomethacin suppresses growth of colon cancer via inhibition of angiogenesis in vivoQ34382230
Post-translational glycoprotein modifications regulate colon cancer stem cells and colon adenoma progression in Apc(min/+) mice through altered Wnt receptor signalingQ34467671
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Cell surface glycan alterations in epithelial mesenchymal transition process of Huh7 hepatocellular carcinoma cellQ34970766
Pancreatic satellite cells derived galectin-1 increase the progression and less survival of pancreatic ductal adenocarcinomaQ35111396
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Integrated Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) Quantitative Proteomic Analysis Identifies Galectin-1 as a Potential Biomarker for Predicting Sorafenib ResistQ35692109
Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1.Q35713332
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Reduced Expression of Galectin-9 Contributes to a Poor Outcome in Colon Cancer by Inhibiting NK Cell Chemotaxis Partially through the Rho/ROCK1 Signaling PathwayQ35974260
Circulating Galectin-1 and 90K/Mac-2BP Correlated with the Tumor Stages of Patients with Colorectal CancerQ36095578
Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinomaQ36149299
Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcomaQ36340825
Suppression of anti-cancer immunity by regulatory T cells: back to the futureQ36352541
A proteomic approach to the identification of new tPA receptors in pancreatic cancer cellsQ36424099
Galectin-1: a small protein with major functionsQ36535706
Expression of annexin-A1 and galectin-1 anti-inflammatory proteins and mRNA in chronic gastritis and gastric cancerQ36616418
Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinomaQ36625697
Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survivalQ36819503
Galectin-1 mediates TGF-β-induced transformation from normal fibroblasts into carcinoma-associated fibroblasts and promotes tumor progression in gastric cancerQ36879539
MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanismQ37033307
N-Glycans in cancer progressionQ37243167
Pancreatic tumor pathogenesis reflects the causative genetic lesionQ37359551
Galectin-1 is essential for efficient liver regeneration following hepatectomyQ37362507
Galectin-1 from cancer-associated fibroblasts induces epithelial-mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancerQ37410368
Quantitative proteomics investigation of pancreatic intraepithelial neoplasiaQ37416043
Advanced colorectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-upQ37489147
Expression of galectin-1 in malignant tumors.Q37529237
Colorectal cancer biomarkers: to be or not to be? Cautionary tales from a road well travelledQ37578725
Stars and stripes in pancreatic cancer: role of stellate cells and stroma in cancer progressionQ37583130
MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinomaQ37636762
Deregulation of annexin-A1 and galectin-1 expression in precancerous gastric lesions: intestinal metaplasia and gastric ulcerQ37639722
Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathwayQ37696353
Diagnostic accuracy of computed tomography for colon cancer staging: A systematic reviewQ37866809
The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and DiseaseQ37899185
Branched N-glycans and their implications for cell adhesion, signaling and clinical applications for cancer biomarkers and in therapeuticsQ37970602
Medical therapies for hepatocellular carcinoma: a critical view of the evidenceQ38059437
Unraveling galectin-1 as a novel therapeutic target for cancerQ38129509
Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinomaQ38174863
Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cellsQ38301301
Glycogenes mediate the invasive properties and chemosensitivity of human hepatocarcinoma cellsQ38320455
Galectin-1 is an inductor of pancreatic stellate cell activationQ38323328
Lactose-binding lectin expression in human colorectal carcinomas. Relation to tumor progressionQ38334678
Increased content of an endogenous lactose-binding lectin in human colorectal carcinoma progressed to metastatic stagesQ38337272
Galectin-1 sensitizes carcinoma cells to anoikis via the fibronectin receptor α5β1-integrin.Q38339024
Inhibition of human HT-29 colon carcinoma cell adhesion by a 4-fluoro-glucosamine analogueQ38354491
Gene expression profile analysis in human hepatocellular carcinoma by cDNA microarray.Q38358877
Upregulation of galectins-1 and -3 in human colon cancer and their role in regulating cell migrationQ38359998
Galectin expression in cancer diagnosis and prognosis: A systematic review.Q38394821
Glyco-nano-oncology: Novel therapeutic opportunities by combining small and sweetQ38726096
Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclusteringQ38777463
Shaping the Immune Landscape in Cancer by Galectin-Driven Regulatory PathwaysQ38796373
Cancer-associated fibroblasts promote angiogenesis in gastric cancer through galectin-1 expressionQ38839374
Targeted diagnostic magnetic nanoparticles for medical imaging of pancreatic cancerQ38851181
Galectin-1 triggers epithelial-mesenchymal transition in human hepatocellular carcinoma cellsQ38932655
E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V.Q39152300
Galectin-1 and Galectin-3 Mediate Protocadherin-24-Dependent Membrane Localization of β-catenin in Colon Cancer Cell Line HCT116Q39250900
Expression of Forkhead box P3 in tumour cells causes immunoregulatory function of signet ring cell carcinoma of the stomachQ39351950
Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endotheliumQ39470886
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P433issue29
P407language of work or nameEnglishQ1860
P921main subjectsignal transductionQ828130
neovascularizationQ1281049
Galectin 1Q5518317
gastrointestinal neoplasmQ58833942
neoplastic gene expression regulationQ66660300
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)5266-5281
P577publication date2017-08-01
2017-08-07
P13046publication type of scholarly workreview articleQ7318358
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleContribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression
P478volume23

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cites work (P2860)
Q64942973Exosomes in the Oncobiology, Diagnosis, and Therapy of Hepatic Carcinoma: A New Player of an Old Game.
Q91610628Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver

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