Galectin-1 and its involvement in hepatocellular carcinoma aggressiveness

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Galectin-1 and its involvement in hepatocellular carcinoma aggressiveness is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1068965224
P356DOI10.2119/MOLMED.2009.00119
P932PMC publication ID2829614
P698PubMed publication ID20200618
P5875ResearchGate publication ID41722426

P50authorRoberta RussoQ37829988
Mario CapassoQ37829998
Natalia RossoQ37838341
Massimo RoncalliQ37839163
Luigi TornilloQ40856429
Claudio TiribelliQ41817157
P2093author name stringDaniela Spano
Achille Iolascon
Luigi M Terracciano
Vittorio Di Maso
P2860cites workIncreased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinomaQ83118257
The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiationQ24292715
The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretionQ24312686
Predominant expression of human zic in cerebellar granule cell lineage and medulloblastomaQ24314663
The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylationQ24317091
The estrogen-responsive B box protein is a novel regulator of the retinoid signalQ24319942
Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormonesQ24532164
Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancerQ24681820
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Global cancer statistics, 2002Q27860562
Summaries of Affymetrix GeneChip probe level dataQ27860888
Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factorsQ28143666
Galectins and cancerQ28201134
90K (Mac-2 BP) and galectins in tumor progression and metastasisQ28242012
The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesionQ28261581
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell divisionQ28299789
Hepatocellular carcinoma: epidemiology and molecular carcinogenesisQ28306363
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisitedQ29547915
Management of hepatocellular carcinomaQ29616230
Tumor metastasis: mechanistic insights and clinical challengesQ29617676
Growth of human hepatoma cells lines with differentiated functions in chemically defined mediumQ29617962
Galectin-1 expression in cancer-associated stromal cells correlates tumor invasiveness and tumor progression in breast cancerQ33274095
Comparative proteomic expression profile in all-trans retinoic acid differentiated neuroblastoma cell lineQ33287185
Management of hepatocellular carcinoma.Q33993264
The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formationQ34134233
Gene expression in fixed tissues and outcome in hepatocellular carcinoma.Q34235518
Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contactsQ34301673
Galectins as modulators of tumour progressionQ34381235
Hepatocellular carcinoma--cause, treatment and metastasisQ34512068
A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.Q34579605
Genetic mechanisms of hepatocarcinogenesisQ34611410
Growth and spread of hepatocellular carcinoma. A review of 240 consecutive autopsy casesQ34630689
The opioid growth factor (OGF)-OGF receptor axis uses the p16 pathway to inhibit head and neck cancerQ34708251
Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapyQ35127584
A decade's studies on metastasis of hepatocellular carcinomaQ35611503
PED is overexpressed and mediates TRAIL resistance in human non-small cell lung cancerQ35886689
The roles of aldo-keto reductases in steroid hormone action.Q36006584
The ZIC gene family in development and disease.Q36055612
Galectin-1 as a potential cancer targetQ36078029
Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanismQ36383370
Matrix metalloproteinases and tumor metastasisQ36471104
The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancerQ36477169
Emerging roles for zic genes in early developmentQ36748446
Ezrin/radixin/moesin: versatile controllers of signaling molecules and of the cortical cytoskeletonQ36785712
Focal gains of VEGFA and molecular classification of hepatocellular carcinomaQ36984575
Galectin-1 as a potential therapeutic target in autoimmune disorders and cancerQ37032635
Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signalingQ37446845
Expression of galectin-1 mRNA correlates with the malignant potential of human gliomas and expression of antisense galectin-1 inhibits the growth of 9 glioma cells.Q55476008
The biology of the opioid growth factor receptor (OGFr)Q55954264
Galectin-1 and galectin-3 expression in human bladder transitional-cell carcinomasQ62091891
Expression of galectin-1 in normal human thyroid gland and in differentiated and poorly differentiated thyroid tumorsQ62091898
Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinomaQ63446362
Hormonal control of alpha-fetoprotein secretion in human hepatoma cell lines proliferating in chemically defined mediumQ68947147
Protein secretion of human cultured liver cellsQ69138457
Galectin-1 is expressed by thymic epithelial cells in myasthenia gravisQ71688593
Increased expression of galectin-1 in carcinoma-associated stroma predicts poor outcome in prostate carcinoma patientsQ73420860
Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsiesQ73490475
Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancerQ73644483
Differential expression of galectin 3 and galectin 1 in colorectal cancer progressionQ73933595
Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1Q78127337
Galectin-1 expression in prostate tumor-associated capillary endothelial cells is increased by prostate carcinoma cells and modulates heterotypic cell-cell adhesionQ79097251
Cytokine gene polymorphisms in Italian preterm infants: association between interleukin-10 -1082 G/A polymorphism and respiratory distress syndromeQ79809826
Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpressionQ80516687
Gene expression profiling reveals potential biomarkers of human hepatocellular carcinomaQ38304400
Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype-associated gene expression signatures.Q39840008
Galectin-1 is a major effector of TrkB-mediated neuroblastoma aggressiveness.Q39861429
Galectin-1-mediated tumor invasion and metastasis, up-regulated matrix metalloproteinase expression, and reorganized actin cytoskeletonsQ39874836
Paracrine-stimulated gene expression profile favors estradiol production in breast tumorsQ40273768
Prediction of lymph node metastasis in patients with endometrioid endometrial cancer using expression microarrayQ40359916
Expression of developmentally regulated endothelial cell locus 1 was induced by tumor-derived factors including VEGF.Q40407711
Activation of Galectin-1 gene in human hepatocellular carcinoma involves methylation-sensitive complex formations at the transcriptional upstream and downstream elementsQ40617232
Expression of endogenous galectin-1 and galectin-3 in intrahepatic cholangiocarcinomaQ40817943
Increased expression of the negative growth factor, galactoside-binding protein, gene in transformed thyroid cells and in human thyroid carcinomasQ41591167
Integration of hepatitis B virus DNA into cells of six established human hepatocellular carcinoma cell linesQ41720805
Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implicationsQ41786603
Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinomaQ41918713
Differential expression of galectin-1 and galectin-3 during first trimester human embryogenesisQ42443034
Expression of galectins in head and neck squamous cell carcinomaQ42525183
Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomasQ43011700
Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectinQ44370346
Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostateQ45176154
Galectin fingerprinting in human endometrium and decidua during the menstrual cycle and in early gestationQ45244862
Feature genes of hepatitis B virus-positive hepatocellular carcinoma, established by its molecular discrimination approach using prediction analysis of microarrayQ45533582
Apoptosis of T cells mediated by galectin-1.Q46356564
AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancerQ46842961
Aldo-keto reductase (AKR) 1C3: role in prostate disease and the development of specific inhibitorsQ46897705
CD44 and VEGF expression in extrahepatic metastasis of human hepatocellular carcinoma.Q47236344
Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPasesQ48543365
Galectin-1 is highly expressed in human gliomas with relevance for modulation of invasion of tumor astrocytes into the brain parenchymaQ48958266
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling.Q52087746
Phenotypical stability of a human hepatoma cell line, HuH-7, in long-term culture with chemically defined medium.Q52831788
Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling.Q53613815
P433issue3-4
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)102-115
P577publication date2009-12-21
P1433published inMolecular MedicineQ6895961
P1476titleGalectin-1 and its involvement in hepatocellular carcinoma aggressiveness
P478volume16

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cites work (P2860)
Q38028882Animal lectins: potential antitumor therapeutic targets in apoptosis
Q41334598Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression
Q38985159Evaluation of cytotoxicity and DNA damage response with analysis of intracellular ATM signaling pathways
Q38831575Gal-1 silenced trophoblast tumor cells (BeWo) show decreased syncytium formation and different miRNA production compared to non-target silenced BeWo cells
Q48270428Galectin Targeted Therapy in Oncology: Current Knowledge and Perspectives
Q53284113Galectin-1 Controls the Proliferation and Migration of Liver Sinusoidal Endothelial Cells and Their Interaction With Hepatocarcinoma Cells.
Q33631354Galectin-1 and Galectin-3 mRNA expression in renal cell carcinoma
Q58574738Galectin-1 gene silencing inhibits the activation and proliferation but induces the apoptosis of hepatic stellate cells from mice with liver fibrosis
Q34103149Galectin-1 is part of human trophoblast invasion machinery--a functional study in vitro.
Q46011748Galectin-1 promotes tumor progression via NF-κB signaling pathway in epithelial ovarian cancer.
Q38932655Galectin-1 triggers epithelial-mesenchymal transition in human hepatocellular carcinoma cells
Q35713459Galectin-4 serves as a prognostic biomarker for the early recurrence / metastasis of hepatocellular carcinoma
Q38728270Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line.
Q91610628Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver
Q35970148Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression
Q36972087Hepatocyte polarity
Q38174863Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma
Q47737163Identification of key genes in endometrioid endometrial adenocarcinoma via TCGA database
Q39026528In vitro selection of the 3'-untranslated regions of the human liver mRNA that bind to the HCV nonstructural protein 5B.
Q45885229Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation-mediated hepatocarcinogenesis
Q35016956Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction
Q36545014LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression
Q37636762MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma
Q39578275Novel roles of galectin-1 in hepatocellular carcinoma cell adhesion, polarization, and in vivo tumor growth.
Q35111396Pancreatic satellite cells derived galectin-1 increase the progression and less survival of pancreatic ductal adenocarcinoma
Q36149299Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma
Q38714509The NmrA-like family domain containing 1 pseudogene Loc344887 is amplified in gallbladder cancer and promotes epithelial-mesenchymal transition
Q50101341The emerging role of galectins in high-fatality cancers
Q37831426The immunoregulatory mechanisms of carcinoma for its survival and development

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