| scholarly article | Q13442814 |
| P50 | author | Lanjing Zhang | Q41729848 |
| Robert L Fullem | Q59398168 | ||
| Hiep Tran | Q59398181 | ||
| Joshua K Thackray | Q61268468 | ||
| Jinchuan Xing | Q74609479 | ||
| Oscar Pellón-Cárdenas | Q84076918 | ||
| Om A Kothari | Q95975031 | ||
| P2093 | author name string | Michael P Verzi | |
| Ansu O Perekatt | |||
| Anbo Zhou | |||
| Bailey N Warder | |||
| Emily E Fokas | |||
| Kevin Tong | |||
| Veerin R Sirihorachai | |||
| P2860 | cites work | Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene | Q24529898 |
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| Comprehensive molecular characterization of human colon and rectal cancer | Q24630415 | ||
| Wnt/β-catenin signaling and disease | Q26823272 | ||
| Serrated lesions of the colorectum: review and recommendations from an expert panel | Q26827208 | ||
| A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention. | Q27852431 | ||
| CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer | Q27853326 | ||
| A genetic model for colorectal tumorigenesis | Q27860582 | ||
| Fast gapped-read alignment with Bowtie 2 | Q27860699 | ||
| Identification of stem cells in small intestine and colon by marker gene Lgr5 | Q28131701 | ||
| Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche | Q28239639 | ||
| APC mutations occur early during colorectal tumorigenesis | Q28274764 | ||
| Crypt stem cells as the cells-of-origin of intestinal cancer | Q28304418 | ||
| Cdx2 determines the fate of postnatal intestinal endoderm | Q28504729 | ||
| Wnt proteins are lipid-modified and can act as stem cell growth factors | Q29615009 | ||
| Cells of origin in cancer | Q29619557 | ||
| E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells | Q33589421 | ||
| The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex | Q33615294 | ||
| The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers | Q34280882 | ||
| The intestinal crypt, a prototype stem cell compartment | Q34358606 | ||
| An intestine-specific homeobox gene regulates proliferation and differentiation | Q34370444 | ||
| Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2 | Q34404177 | ||
| Oncogenic Braf induces melanocyte senescence and melanoma in mice | Q34974162 | ||
| Loss of CDX2 expression is associated with poor prognosis in colorectal cancer patients | Q35045711 | ||
| RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers | Q35095334 | ||
| A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors | Q35649378 | ||
| Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma | Q35774120 | ||
| Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells | Q35845010 | ||
| Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1). | Q36061304 | ||
| CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer | Q36312135 | ||
| Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype | Q37086982 | ||
| BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis. | Q37608879 | ||
| Role of the serrated pathway in colorectal cancer pathogenesis | Q37737403 | ||
| Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions | Q39166874 | ||
| Smad4 restoration leads to a suppression of Wnt/beta-catenin signaling activity and migration capacity in human colon carcinoma cells | Q39873345 | ||
| The Intestinal Wnt/TCF Signature. | Q40167195 | ||
| V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a | Q42059658 | ||
| Tissue-specific and inducible Cre-mediated recombination in the gut epithelium | Q44999476 | ||
| Endoscopic features of sessile serrated adenomas: validation by international experts using high-resolution white-light endoscopy and narrow-band imaging | Q45716629 | ||
| Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. | Q50501238 | ||
| Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity. | Q50642659 | ||
| Visualization of a short-range Wnt gradient in the intestinal stem-cell niche. | Q52885366 | ||
| Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma. | Q53205541 | ||
| Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer. | Q53260087 | ||
| BRAF-mutated microsatellite stable colorectal carcinoma: an aggressive adenocarcinoma with reduced CDX2 and increased cytokeratin 7 immunohistochemical expression. | Q54346395 | ||
| Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts | Q57002669 | ||
| Conversion of gastric mucosa to intestinal metaplasia in Cdx2-expressing transgenic mice | Q74250578 | ||
| Generation of Smad4/Dpc4 conditional knockout mice | Q77668147 | ||
| Molecular Genetics of Colorectal Cancer | Q82521439 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 13 | |
| P921 | main subject | colorectal cancer | Q188874 |
| P304 | page(s) | 3833-3845 | |
| P577 | publication date | 2017-12-01 | |
| P1433 | published in | Cell Reports | Q5058165 |
| P1476 | title | Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer | |
| P478 | volume | 21 |
| Q93018032 | A model for RAS mutation patterns in cancers: finding the sweet spot |
| Q99566645 | A smooth muscle-derived, BRAF-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin |
| Q98463864 | BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation |
| Q93046337 | CK7 and consensus molecular subtypes as major prognosticators in V600EBRAF mutated metastatic colorectal cancer |
| Q91564745 | Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium |
| Q55411157 | Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells. |
| Q92331830 | Directional association test reveals high-quality putative cancer driver biomarkers including noncoding RNAs |
| Q91584962 | Identification of key candidate genes for colorectal cancer by bioinformatics analysis |
| Q50026745 | Metaplastic Cdx2-depleted cells can be very disruptive neighbors. |
| Q58776529 | Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer |
| Q93022810 | Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling |
| Q89480288 | SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium |
| Q91310933 | Serrated Colorectal Cancer: The Road Less Travelled? |
| Q50036749 | The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms. |
| Q90608763 | Wnt signaling suppresses MAPK-driven proliferation of intestinal stem cells |
| Q98652622 | α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer |
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