Aberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer.

scientific article published on 29 March 2018

Aberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OL.2018.8382
P8608Fatcat IDrelease_hdmtif24mbbttcgxlm3mfs3gei
P932PMC publication ID5950537
P698PubMed publication ID29805583

P50authorFarhan Ul HaqQ59708414
P2093author name stringMuhammad Saeed
Hazir Rahman
Noor Muhammad
Nawab Ali
Farman Ullah Farman
P2860cites workE2F4 modulates differentiation and gene expression in hematopoietic progenitor cells during commitment to the lymphoid lineage.Q50801055
Retinoblastoma (RB1) pocket domain mutations and promoter hyper-methylation in head and neck cancer.Q53045539
E2F4 loss suppresses tumorigenesis in Rb mutant mice.Q54798619
Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumorsQ73436895
Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomasQ79401919
Molecular Genetics of Colorectal CancerQ82521439
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Genomic structure and mutation screening of the E2F4 gene in human tumorsQ28143600
E2F-4, a new member of the E2F transcription factor family, interacts with p107Q28240565
E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivoQ28240575
Control of cell cycle transcription during G1 and S phasesQ28295030
E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivoQ28585017
Epigenetics in cancerQ29617139
E2F: a link between the Rb tumor suppressor protein and viral oncoproteinsQ29618375
MethPrimer: designing primers for methylation PCRsQ29618664
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cellsQ33589421
Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex.Q33890688
Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.Q34063326
DNA methyltransferases, DNA damage repair, and cancerQ34298096
Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysisQ34947016
E2F4 regulatory program predicts patient survival prognosis in breast cancerQ35000629
Emerging roles of E2Fs in cancer: an exit from cell cycle controlQ35009182
Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoterQ35019557
Overexpression of E2F mRNAs associated with gastric cancer progression identified by the transcription factor and miRNA co-regulatory network analysisQ35043503
Promoter hypermethylation of tumour suppressor genes as potential biomarkers in colorectal cancerQ35138892
Genome-wide analysis reveals DNA methylation markers that vary with both age and obesityQ35204587
Promoter Methylation Status Modulate the Expression of Tumor Suppressor (RbL2/p130) Gene in Breast CancerQ35745193
E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinomaQ36996106
Aberrant Promoter Methylation at CpG Cytosines Induce the Upregulation of the E2F5 Gene in Breast CancerQ37056909
Survival-related profile, pathways, and transcription factors in ovarian cancerQ37081275
MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasiaQ37289662
Epigenetic regulation in cancer progressionQ38463713
Cell cycle-related transformation of the E2F4-p130 repressor complexQ40375347
Identification of twenty-two candidate markers for human osteogenic sarcomaQ40768894
Exogenous E2F expression is growth inhibitory before, during, and after cellular transformationQ42801645
E2F4 deficiency promotes drug-induced apoptosisQ45196180
Preparation of genomic DNA from mammalian tissueQ46761054
Nuclear and cytoplasmic mRNA quantification by SYBR green based real-time RT-PCR.Q50720123
P433issue6
P304page(s)8461-8469
P577publication date2018-03-29
P1433published inOncology LettersQ20640514
P1476titleAberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer
P478volume15

Reverse relations

Q93379565Prognostic values of E2F mRNA expression in human gastric cancercites workP2860

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