E2F4 regulatory program predicts patient survival prognosis in breast cancer

scientific article

E2F4 regulatory program predicts patient survival prognosis in breast cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1021619841
P356DOI10.1186/S13058-014-0486-7
P932PMC publication ID4303196
P698PubMed publication ID25440089
P5875ResearchGate publication ID269177869

P2093author name stringChao Cheng
Matthew Ung
Erik H Andrews
James DiRenzo
Sari S Khaleel
P2860cites workGene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohortsQ25257621
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsQ27860709
Gene expression profiling predicts clinical outcome of breast cancerQ27860732
A gene-expression signature as a predictor of survival in breast cancerQ27860945
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteinsQ27861094
Genomic structure and mutation screening of the E2F4 gene in human tumorsQ28143600
The Ki-67 protein: from the known and the unknownQ28143714
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancerQ28297827
Genomic structure and mutation screening of theE2F4 gene in human tumorsQ29302593
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancerQ29615523
Architecture of the human regulatory network derived from ENCODE dataQ29617046
Supervised risk predictor of breast cancer based on intrinsic subtypesQ29617404
Identification of genes periodically expressed in the human cell cycle and their expression in tumorsQ29619131
Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosisQ30004190
Molecular profiling of human cancerQ30659943
Gene expression omnibus: microarray data storage, submission, retrieval, and analysisQ31057685
Inferring activity changes of transcription factors by binding association with sorted expression profilesQ33306147
ROCK: a resource for integrative breast cancer data analysis.Q50917397
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.Q51940347
Prognostic value of breast cancer subtypes, Ki-67 proliferation index, age, and pathologic tumor characteristics on breast cancer survival in Caucasian women.Q53119241
The role of transcription factors in circadian gene expression.Q53827788
Gene-expression profiling in breast cancerQ58048628
Prediction of cancer outcome with microarrays: a multiple random validation strategyQ62785637
The Nottingham prognostic index in primary breast cancerQ64019104
Ki-67 Staining as a Means to Simplify Analysis of Tumor Cell ProliferationQ67699920
Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumorsQ73436895
Evaluation of malignancy using Ki-67 labeling index for gastric stromal tumorQ79103226
The humoral immune system has a key prognostic impact in node-negative breast cancerQ81561686
Biology and clinical relevance of the micropthalmia family of transcription factors in human cancerQ84353474
Systematic identification of cell cycle regulated transcription factors from microarray time series dataQ33322233
Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifenQ33337206
Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger ageQ33378354
Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancerQ33650639
Control of apoptosis by Rel/NF-kappaB transcription factorsQ33797163
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survivalQ33939753
Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemiaQ34313643
Transcription factor binding profiles reveal cyclic expression of human protein-coding genes and non-coding RNAs.Q34845075
REACTIN: regulatory activity inference of transcription factors underlying human diseases with application to breast cancerQ34865218
Transcription factors as targets for cancer therapyQ34932264
Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysisQ34947016
Genomic and personalized medicine: foundations and applicationsQ35014059
Transcription factors and cancer: an overviewQ35035473
TIP: a probabilistic method for identifying transcription factor target genes from ChIP-seq binding profilesQ35571086
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer.Q36073367
Epigenetic reprogramming in cancerQ37291110
Transcription factors involved in lens development from the preplacodal ectodermQ37978029
Clinical validity/utility, change in practice patterns, and economic implications of risk stratifiers to predict outcomes for early-stage breast cancer: a systematic reviewQ38024305
EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.Q38040369
A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescenceQ38308285
Mining for regulatory programs in the cancer transcriptomeQ38325769
Regulation of cell proliferation by the E2F transcription factorsQ40864375
Breast cancer molecular subtypes respond differently to preoperative chemotherapyQ42482998
Ectopic expression of cyclin E in estrogen responsive cells abrogates antiestrogen mediated growth arrestQ44049464
Prediction of recurrence-free survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expressionQ44571511
Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation seriesQ44811326
The importance of gene-centring microarray dataQ46051909
The prognostic significance of Jun transcription factors in ovarian cancerQ47784628
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P433issue6
P921main subjectbreast cancerQ128581
patientQ181600
P304page(s)486
P577publication date2014-12-02
P1433published inBreast Cancer ResearchQ2208481
P1476titleE2F4 regulatory program predicts patient survival prognosis in breast cancer
P478volume16

Reverse relations

cites work (P2860)
Q47590835A P53-Deficiency Gene Signature Predicts Recurrence Risk of Patients with Early-Stage Lung Adenocarcinoma
Q64256232A data-driven interactome of synergistic genes improves network-based cancer outcome prediction
Q55211165Aberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer.
Q36769000Analysis of TRRAP as a Potential Molecular Marker and Therapeutic Target for Breast Cancer
Q64110537Applications of ENCODE data to Systematic Analyses via Data Integration
Q42955158Cancer cell line specific co-factors modulate the FOXM1 cistrome
Q91657562Computational STAT3 activity inference reveals its roles in the pancreatic tumor microenvironment
Q36253768Contextual Refinement of Regulatory Targets Reveals Effects on Breast Cancer Prognosis of the Regulome
Q36526008E2F4 Program Is Predictive of Progression and Intravesical Immunotherapy Efficacy in Bladder Cancer
Q62785312ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors
Q90312211Identification of Alternatively-Activated Pathways between Primary Breast Cancer and Liver Metastatic Cancer Using Microarray Data
Q37276814Integrative Genomic Analyses Yield Cell-Cycle Regulatory Programs with Prognostic Value
Q35177024Integrative analysis of survival-associated gene sets in breast cancer
Q38785789Liquid biopsy on chip: a paradigm shift towards the understanding of cancer metastasis
Q93005381Mining Featured Biomarkers Linked with Epithelial Ovarian CancerBased on Bioinformatics
Q93379565Prognostic values of E2F mRNA expression in human gastric cancer
Q37710898SWIM: a computational tool to unveiling crucial nodes in complex biological networks
Q64061316Serve as Potential Prognostic Biomarkers and Targets for Human Ovarian Cancer
Q28069626Targeting the RB-E2F pathway in breast cancer
Q43216761The E2F4 prognostic signature is also predictive of the pathological response of breast cancer to chemotherapy
Q33630465The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients
Q26748969The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
Q39612810The pan-cancer pathological regulatory landscape
Q33591690Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer
Q36103183iTAR: a web server for identifying target genes of transcription factors using ChIP-seq or ChIP-chip data

Search more.