Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia

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Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia is …
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scholarly articleQ13442814

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P356DOI10.1056/NEJMOA031046
P8608Fatcat IDrelease_plhs3s6xkveb5dxdr54qzp6ghy
P698PubMed publication ID15084693

P50authorRobert TibshiraniQ3938444
Jonathan R. PollackQ73921770
Eric BairQ55483301
Hartmut DöhnerQ66385451
Konstanze DöhnerQ66385457
P2093author name stringLars Bullinger
Richard F Schlenk
Stefan Fröhling
P2860cites workDistinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
adult acute myeloid leukemiaQ53673331
P304page(s)1605-1616
P577publication date2004-04-01
P1433published inThe New England Journal of MedicineQ582728
P1476titleUse of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia
P478volume350

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Q33384448Randomization in laboratory procedure is key to obtaining reproducible microarray results
Q37206159Recent advances in the molecular diagnosis and prognosis of colorectal cancer
Q47565861Reconstruction of molecular network evolution from cross-sectional omics data
Q52817300Recurrent Cytogenetic Abnormalities in Acute Myeloid Leukemia
Q24634204Recurring mutations found by sequencing an acute myeloid leukemia genome
Q64103774Reduced protocadherin17 expression in leukemia stem cells: the clinical and biological effect in acute myeloid leukemia
Q37270376Reducing the complexity of complex gene coexpression networks by coupling multiweighted labeling with topological analysis
Q37450557Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression
Q37080843Review: genetic models of acute myeloid leukaemia
Q37419348Risk assessment before allogeneic hematopoietic cell transplantation for older adults with acute myeloid leukemia
Q33286957Robust interlaboratory reproducibility of a gene expression signature measurement consistent with the needs of a new generation of diagnostic tools
Q52566507Robust sparse accelerated failure time model for survival analysis.
Q37810111Role of gene-expression profiling in chronic myeloid leukemia
Q54652926Routine expression profiling of microarray gene signatures in acute leukaemia by real-time PCR of human bone marrow.
Q34144877Routine use of microarray-based gene expression profiling to identify patients with low cytogenetic risk acute myeloid leukemia: accurate results can be obtained even with suboptimal samples
Q58576722S100 Proteins in Acute Myeloid Leukemia
Q37610020SPARC: a matricellular regulator of tumorigenesis
Q53515190SSX2IP expression in acute myeloid leukaemia: an association with mitotic spindle failure in t(8;21), and cell cycle in t(15;17) patients.
Q92519522Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics
Q38204373Semi-supervised clustering methods
Q34180853Semi-supervised recursively partitioned mixture models for identifying cancer subtypes
Q53590608Single nucleotide polymorphisms of cytarabine metabolic genes influence clinical outcome in acute myeloid leukemia patients receiving high-dose cytarabine therapy
Q51856192Stem cell gene expression programs influence clinical outcome in human leukemia.
Q36117881Strategic plans to promote head and neck cancer translational research within the radiation therapy oncology group: a report from the translational research program
Q36007347Stratification of acute myeloid leukemia based on gene expression profiles
Q83645730Stratification of pediatric acute myeloid leukemia through cancer cell gene-expression profiling
Q47760063Surveillance of transcriptomes in basic military trainees with normal, febrile respiratory illness, and convalescent phenotypes.
Q36310257Systematic analysis of hematopoietic gene expression profiles for prognostic prediction in acute myeloid leukemia
Q38354101Systematic identification of transcription factors associated with patient survival in cancers
Q38096025Systems level immune response analysis and personalized medicine
Q34988140T-ReCS: stable selection of dynamically formed groups of features with application to prediction of clinical outcomes
Q43559106Testing the prediction error difference between 2 predictors
Q40740405The Beginning of the Road for Non-Coding RNAs in Normal Hematopoiesis and Hematologic Malignancies
Q89457595The M2 macrophage marker CD206: a novel prognostic indicator for acute myeloid leukemia
Q36591431The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia
Q38083604The Possible Diagnostic and Prognostic Use of Systemic Chemokine Profiles in Clinical Medicine—The Experience in Acute Myeloid Leukemia from Disease Development and Diagnosis via Conventional Chemotherapy to Allogeneic Stem Cell Transplantation
Q37671778The challenge of risk stratification in acute myeloid leukemia with normal karyotype
Q31033394The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Q88790380The future may be closer than you think: a response from the Personalized Medicine Coalition to the Royal Society's report on personalized medicine
Q24683173The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
Q28544750The human immune response to tuberculosis and its treatment: a view from the blood
Q98566206The mitochondrial transcription machinery genes are upregulated in acute myeloid leukemia and associated with poor clinical outcome
Q57286200The modular network structure of the mutational landscape of Acute Myeloid Leukemia
Q36939043The molecular characterization and clinical management of multiple myeloma in the post-genome era.
Q34530992The molecular classification of multiple myeloma
Q33241398The molecular portraits of breast tumors are conserved across microarray platforms
Q33386662The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension
Q91752975The power and potential of integrated diagnostics in acute myeloid leukaemia
Q36148564The promise of molecular profiling for cancer identification and treatment
Q37900755The role of gene expression profiling in drug discovery
Q37738548The role of molecular tests in acute myelogenous leukemia treatment decisions
Q38198569The use of molecular genetics to refine prognosis in acute myeloid leukemia
Q36773687The use of transcriptomic biomarkers for personalized medicine
Q37271941Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years
Q51818965Therapeutic targeting of leukemic stem cells in acute myeloid leukemia - the biological background for possible strategies
Q37586897Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia
Q36970214Transcriptional dysregulation during myeloid transformation in AML.
Q40075629Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia
Q36412663Transcriptional profiling of peripheral blood cells in clinical pharmacogenomic studies
Q27853347Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade
Q36411676Translating genomic biomarkers into clinically useful diagnostics
Q42153188Truncated RUNX1 protein generated by a novel t(1;21)(p32;q22) chromosomal translocation impairs the proliferation and differentiation of human hematopoietic progenitors
Q36101066Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia
Q35849255Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.
Q41252330Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis.
Q55291688Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia.
Q30992230Use of extreme patient samples for outcome prediction from gene expression data.
Q36607291Use of gene expression microarrays for the study of acute leukemia
Q35873673Using microarrays to predict resistance to chemotherapy in cancer patients
Q38760619Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling.
Q38029546Vascular endothelial growth factor signaling in acute myeloid leukemia
Q33775647What are the endpoints of therapy for acute leukemias? Old definitions and new challenges
Q38700338ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.
Q81399255[DNA-chips in the diagnosis of hematological malignancies]
Q42251074c-Met inhibition in a HOXA9/Meis1 model of CN-AML.
Q33936093ccSVM: correcting Support Vector Machines for confounding factors in biological data classification
Q39039867miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism
Q38313725siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.

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