scholarly article | Q13442814 |
P50 | author | Daniel B Costa | Q55130362 |
Emmanuelle Passegué | Q85405999 | ||
Christian Steidl | Q86259717 | ||
Ulrich Steidl | Q88334096 | ||
Roel G W Verhaak | Q88447576 | ||
Manuel Aivado | Q117223389 | ||
Towia A Libermann | Q44211169 | ||
Daniel G Tenen | Q44797022 | ||
Hasan H. Otu | Q48611090 | ||
P2093 | author name string | Ruud Delwel | |
Peter J M Valk | |||
Guido Kobbe | |||
Xuesong Gu | |||
Frank Rosenbauer | |||
Katharina Wagner | |||
Steffen Klippel | |||
Ingmar Bruns | |||
Alexander Ebralidze | |||
P2860 | cites work | Permutation-validated principal components analysis of microarray data | Q24793935 |
Heterozygous PU.1 mutations are associated with acute myeloid leukemia | Q52546734 | ||
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1. | Q52567432 | ||
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. | Q53362332 | ||
The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia | Q57615556 | ||
Regulation of the PU.1 gene by distal elements | Q57615588 | ||
The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow | Q78863113 | ||
Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways | Q80551984 | ||
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1 | Q81119990 | ||
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance | Q81308407 | ||
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib | Q27824829 | ||
Stem cells, cancer, and cancer stem cells | Q27860878 | ||
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation | Q28200070 | ||
Repression of I-Aβ Gene Expression by the Transcription Factor PU.1 | Q28511025 | ||
A role for Wnt signalling in self-renewal of haematopoietic stem cells | Q28592213 | ||
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML | Q29614278 | ||
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells | Q29615006 | ||
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages | Q29615010 | ||
"Stemness": transcriptional profiling of embryonic and adult stem cells | Q29618765 | ||
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element | Q33707708 | ||
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors | Q33889234 | ||
A stem cell molecular signature | Q34149366 | ||
Prospective isolation of human clonogenic common myeloid progenitors | Q34154606 | ||
Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia | Q34313643 | ||
Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? | Q34542144 | ||
Focus on acute leukemias | Q34747215 | ||
Disruption of differentiation in human cancer: AML shows the way. | Q35058575 | ||
Effect of transcription-factor concentrations on leukemic stem cells. | Q35848111 | ||
Cancer stem cells: lessons from leukemia. | Q36220217 | ||
Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine | Q37348764 | ||
Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia | Q38287713 | ||
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance | Q38321981 | ||
c-Jun is a JNK-independent coactivator of the PU.1 transcription factor. | Q38328224 | ||
Dynamics of chronic myeloid leukaemia. | Q40403398 | ||
Cooperation between antioxidants and 1,25-dihydroxyvitamin D3 in induction of leukemia HL60 cell differentiation through the JNK/AP-1/Egr-1 pathway. | Q42476212 | ||
Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia | Q44066922 | ||
Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediators | Q44796947 | ||
Gene expression profiling identifies significant differences between the molecular phenotypes of bone marrow-derived and circulating human CD34+ hematopoietic stem cells | Q47571879 | ||
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. | Q47597394 | ||
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity | Q47634506 | ||
Prognostically useful gene-expression profiles in acute myeloid leukemia | Q51999490 | ||
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells | Q52086238 | ||
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo | Q52121269 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | leukemia | Q29496 |
P304 | page(s) | 1269-1277 | |
P577 | publication date | 2006-10-15 | |
P1433 | published in | Nature Genetics | Q976454 |
P1476 | title | Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells | |
P478 | volume | 38 |
Q38888701 | 2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development. |
Q35921510 | A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia. |
Q33939662 | A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1. |
Q39313400 | A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression |
Q34056156 | A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia |
Q41969007 | AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon Carcinomas |
Q80362481 | Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia |
Q45345512 | Activation of CCAAT/enhancer-binding protein alpha or PU.1 in hematopoietic stem cells leads to their reduced self-renewal and proliferation |
Q47161998 | An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program. |
Q36880647 | Analysis of concentration-dependent functions of PU.1 in hematopoiesis using mouse models |
Q64970925 | Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells. |
Q91752053 | Blood disease-causing and -suppressing transcriptional enhancers: general principles and GATA2 mechanisms |
Q54325366 | CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia. |
Q28533973 | Cancer Subtype Discovery and Biomarker Identification via a New Robust Network Clustering Algorithm |
Q42446442 | Characterization of the promoter region of the human PARG gene and its response to PU.1 during differentiation of HL-60 cells |
Q34647637 | Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cells |
Q30413034 | Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo |
Q92796495 | Down-Regulation of PU.1 Gene in Pediatric Acute Lymphoblastic Leukemia Patients from South of Iran |
Q33385999 | Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome |
Q33401421 | Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation |
Q29620566 | Endothelial-to-mesenchymal transition contributes to cardiac fibrosis |
Q39179850 | Epigenetic regulation of the metallothionein-1A promoter by PU.1 during differentiation of THP-1 cells |
Q36982190 | FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors |
Q33720872 | Genome organizing function of SATB1 in tumor progression |
Q37127231 | Getting to the stem of chronic myeloid leukaemia |
Q53325167 | Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells? |
Q41901150 | H2.0-like Homeobox Regulates Early Hematopoiesis and Promotes Acute Myeloid Leukemia |
Q43051719 | HLX in AML: novel prognostic and therapeutic target |
Q37602230 | HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia |
Q33996801 | Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network |
Q37163021 | Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells |
Q35607293 | IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells |
Q33560404 | Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia. |
Q37588235 | Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model |
Q37302271 | Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants |
Q40036212 | Interaction between the homeodomain protein HOXC13 and ETS family transcription factor PU.1 and its implication in the differentiation of murine erythroleukemia cells. |
Q36710812 | JunB breakdown in mid-/late G2 is required for down-regulation of cyclin A2 levels and proper mitosis |
Q35839788 | JunB contributes to Id2 repression and the epithelial-mesenchymal transition in response to transforming growth factor-β. |
Q43089046 | JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal. |
Q91062866 | LSD1-mediated repression of GFI1 super-enhancer plays an essential role in erythroleukemia |
Q51656403 | Lenalidomide consolidation treatment in patients with multiple myeloma suppresses myelopoieses but spares erythropoiesis |
Q79954772 | Lentiviral PU.1 overexpression restores differentiation in myeloid leukemic blasts |
Q33882944 | Lnk constrains myeloproliferative diseases in mice |
Q24298666 | Metallothionein-1 isoforms and vimentin are direct PU.1 downstream target genes in leukemia cells |
Q42165465 | Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia. |
Q33576478 | Minireview: Nuclear receptors, hematopoiesis, and stem cells |
Q26999068 | Mouse Models for Efficacy Testing of Agents against Radiation Carcinogenesis — A Literature Review |
Q26747129 | Mouse models for radiation-induced cancers |
Q37812866 | Multi-parameter fluorescence-activated cell sorting and analysis of stem and progenitor cells in myeloid malignancies |
Q24289050 | Multiplex meta-analysis of RNA expression to identify genes with variants associated with immune dysfunction |
Q64959928 | Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level. |
Q54642331 | Myeloid Leukemia Development in c-Cbl RING Finger Mutant Mice Is Dependent on FLT3 Signaling |
Q92955612 | Old dog PU.1 reveals new tricks |
Q36163066 | Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS. |
Q26863329 | PU.1 downregulation in murine radiation-induced acute myeloid leukaemia (AML): from molecular mechanism to human AML |
Q36802972 | PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element. |
Q46873766 | Pharmacological inhibition of the transcription factor PU.1 in leukemia |
Q47979002 | Pin1-mediated prolyl isomerization of Runx1 affects PU.1 expression in pre-monocytes |
Q37620148 | Polycomb group proteins: navigators of lineage pathways led astray in cancer |
Q34024957 | Radiation-induced myeloid leukemia in murine models |
Q34707445 | Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice |
Q42580360 | Regulation of GSK3β-FBXW7-JUNB Axis |
Q28508569 | Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c |
Q38092683 | Regulation of monocyte differentiation by specific signaling modules and associated transcription factor networks |
Q38221005 | Role of tissue-specific AT-rich DNA sequence-binding proteins in lymphocyte differentiation |
Q41530060 | SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells |
Q41769694 | Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia |
Q96683908 | Single-molecule imaging of transcription dynamics in somatic stem cells |
Q30398272 | Small molecule inhibitors targeting activator protein 1 (AP-1). |
Q35525433 | Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia |
Q38761791 | Stem and progenitor cell alterations in myelodysplastic syndromes |
Q36220721 | Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations |
Q38171230 | Stem cell origin of myelodysplastic syndromes |
Q43418051 | Suppression of Pu.1 function results in expanded myelopoiesis in zebrafish |
Q58563626 | T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1 |
Q37109225 | Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. |
Q37272565 | Targeting the leukemic stem cell: the Holy Grail of leukemia therapy |
Q34673600 | The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation |
Q34616532 | The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells |
Q34318485 | The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells |
Q49601775 | The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression |
Q33955558 | The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway. |
Q33968294 | The transcription factor PU.1 regulates γδ T cell homeostasis |
Q36970209 | Transcriptional control of granulocyte and monocyte development |
Q42264910 | Trim14 overexpression causes the same transcriptional changes in mouse embryonic stem cells and human HEK293 cells |
Q55297811 | Unsupervised clustering and epigenetic classification of single cells. |
Q36366924 | Widespread over-expression of the non-clustered homeobox gene HLX in acute myeloid leukemia |
Q28081638 | Zebrafish as a model for leukemia and other hematopoietic disorders |
Q42257522 | c-Jun homodimers can function as a context-specific coactivator |
Q33808684 | chinmo is a functional effector of the JAK/STAT pathway that regulates eye development, tumor formation, and stem cell self-renewal in Drosophila |
Q34961818 | β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors |
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