Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells

scientific article published on 15 October 2006

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NG1898
P698PubMed publication ID17041602
P5875ResearchGate publication ID6753203

P50authorDaniel B CostaQ55130362
Emmanuelle PasseguéQ85405999
Christian SteidlQ86259717
Ulrich SteidlQ88334096
Roel G W VerhaakQ88447576
Manuel AivadoQ117223389
Towia A LibermannQ44211169
Daniel G TenenQ44797022
Hasan H. OtuQ48611090
P2093author name stringRuud Delwel
Peter J M Valk
Guido Kobbe
Xuesong Gu
Frank Rosenbauer
Katharina Wagner
Steffen Klippel
Ingmar Bruns
Alexander Ebralidze
P2860cites workPermutation-validated principal components analysis of microarray dataQ24793935
Heterozygous PU.1 mutations are associated with acute myeloid leukemiaQ52546734
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.Q52567432
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.Q53362332
The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemiaQ57615556
Regulation of the PU.1 gene by distal elementsQ57615588
The in vivo profile of transcription factors during neutrophil differentiation in human bone marrowQ78863113
Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathwaysQ80551984
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1Q81119990
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenanceQ81308407
EGFR mutation and resistance of non-small-cell lung cancer to gefitinibQ27824829
Stem cells, cancer, and cancer stem cellsQ27860878
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulationQ28200070
Repression of I-Aβ Gene Expression by the Transcription Factor PU.1Q28511025
A role for Wnt signalling in self-renewal of haematopoietic stem cellsQ28592213
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CMLQ29614278
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cellsQ29615006
A clonogenic common myeloid progenitor that gives rise to all myeloid lineagesQ29615010
"Stemness": transcriptional profiling of embryonic and adult stem cellsQ29618765
Potential autoregulation of transcription factor PU.1 by an upstream regulatory elementQ33707708
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitorsQ33889234
A stem cell molecular signatureQ34149366
Prospective isolation of human clonogenic common myeloid progenitorsQ34154606
Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemiaQ34313643
Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?Q34542144
Focus on acute leukemiasQ34747215
Disruption of differentiation in human cancer: AML shows the way.Q35058575
Effect of transcription-factor concentrations on leukemic stem cells.Q35848111
Cancer stem cells: lessons from leukemia.Q36220217
Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridineQ37348764
Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemiaQ38287713
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significanceQ38321981
c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.Q38328224
Dynamics of chronic myeloid leukaemia.Q40403398
Cooperation between antioxidants and 1,25-dihydroxyvitamin D3 in induction of leukemia HL60 cell differentiation through the JNK/AP-1/Egr-1 pathway.Q42476212
Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemiaQ44066922
Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediatorsQ44796947
Gene expression profiling identifies significant differences between the molecular phenotypes of bone marrow-derived and circulating human CD34+ hematopoietic stem cellsQ47571879
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.Q47597394
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacityQ47634506
Prognostically useful gene-expression profiles in acute myeloid leukemiaQ51999490
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cellsQ52086238
HOXB4-induced expansion of adult hematopoietic stem cells ex vivoQ52121269
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)1269-1277
P577publication date2006-10-15
P1433published inNature GeneticsQ976454
P1476titleEssential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells
P478volume38

Reverse relations

cites work (P2860)
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