scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.274.8.4939 |
P698 | PubMed publication ID | 9988737 |
P50 | author | Roger John Davis | Q21165803 |
Alan J Whitmarsh | Q42533967 | ||
Daniel G Tenen | Q44797022 | ||
P2093 | author name string | C L Carpenter | |
T Hoang | |||
D E Zhang | |||
G Behre | |||
M P Coghlan | |||
P2860 | cites work | JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 |
Ras-related proteins in signal transduction and growth control | Q24324056 | ||
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1 | Q24339633 | ||
The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB | Q24563487 | ||
Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells | Q24610231 | ||
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 | Q28114883 | ||
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene | Q28116777 | ||
Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice | Q28593712 | ||
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2 | Q28609817 | ||
Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1 | Q33774804 | ||
Normal myeloid development requires both the glutamine-rich transactivation domain and the PEST region of transcription factor PU.1 but not the potent acidic transactivation domain | Q33775074 | ||
Inhibition of hematopoiesis by competitive binding of transcription factor PU.1. | Q35673096 | ||
PU.1 can participate in an active enhancer complex without its transcriptional activation domain | Q35902741 | ||
Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. | Q36364154 | ||
CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter | Q36557608 | ||
Cellular transformation and malignancy induced by ras require c-jun | Q36561672 | ||
Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signaling | Q36566543 | ||
Cell-specific expression of the macrophage scavenger receptor gene is dependent on PU.1 and a composite AP-1/ets motif | Q36656291 | ||
Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1) | Q36671577 | ||
Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells | Q36689171 | ||
Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins | Q36790397 | ||
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. | Q36792845 | ||
PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity | Q36809426 | ||
Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes. | Q38316909 | ||
Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation | Q38320946 | ||
The transcription factor PU.1 is involved in macrophage proliferation | Q38356001 | ||
Serum response factor mediates AP-1-dependent induction of the skeletal alpha-actin promoter in ventricular myocytes | Q38357989 | ||
Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha | Q39724224 | ||
Activation of transcription by PU.1 requires both acidic and glutamine domains | Q40018093 | ||
The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU.1 and c-Jun | Q41056192 | ||
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. | Q41205566 | ||
c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK. | Q41442860 | ||
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor | Q41497311 | ||
The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades | Q41688659 | ||
Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides | Q41962689 | ||
Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation | Q42736547 | ||
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73 | Q42825163 | ||
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. | Q52214235 | ||
A growing coactivator network | Q59080836 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 8 | |
P304 | page(s) | 4939-4946 | |
P577 | publication date | 1999-02-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | c-Jun is a JNK-independent coactivator of the PU.1 transcription factor | |
P478 | volume | 274 |
Q42155062 | A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. |
Q37034852 | Activating PTPN11 mutants promote hematopoietic progenitor cell-cycle progression and survival |
Q37657657 | Acupuncture as anticancer treatment? |
Q47161998 | An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program. |
Q24534022 | An alternative model of H ferritin promoter transactivation by c-Jun |
Q64969303 | Analysis of the promoter region of the human FcRn gene. |
Q33320076 | Analyzing M-CSF dependent monocyte/macrophage differentiation: expression modes and meta-modes derived from an independent component analysis |
Q39452193 | Atypical protein kinases Clambda and -zeta associate with the GTP-binding protein Cdc42 and mediate stress fiber loss |
Q33786904 | BSAP can repress enhancer activity by targeting PU.1 function |
Q39499429 | Characterization of a c-Jun-responsive module in the 5'-flank of the human CYP2J2 gene that regulates transactivation |
Q58326895 | Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage |
Q44683611 | Combinatorial control of DNase I-hypersensitive site formation and erasure by immunoglobulin heavy chain enhancer-binding proteins |
Q38096321 | Concise review: erythroid versus myeloid lineage commitment: regulating the master regulators |
Q46751768 | Conserved ETS domain arginines mediate DNA binding, nuclear localization, and a novel mode of bZIP interaction |
Q46277443 | Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage |
Q73443168 | Context-dependent Pax-5 repression of a PU.1/NF-kappaB regulated reporter gene in B lineage cells |
Q39448135 | Cytomegalovirus IE2 protein stimulates interleukin 1beta gene transcription via tethering to Spi-1/PU.1. |
Q28508344 | Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion. |
Q35058575 | Disruption of differentiation in human cancer: AML shows the way. |
Q47967927 | Downregulation of c-Jun expression and cell cycle regulatory molecules in acute myeloid leukemia cells upon CD44 ligation |
Q34443338 | Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment |
Q38334440 | Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells |
Q38352277 | Elevated c-Jun expression in acute myeloid leukemias inhibits C/EBPalpha DNA binding via leucine zipper domain interaction |
Q44626778 | Erythroblast transformation by FLI-1 depends upon its specific DNA binding and transcriptional activation properties |
Q53341099 | Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells. |
Q40664432 | Ets, Ap-1 and GATA factor families regulate the utrophin B promoter: potential regulatory mechanisms for endothelial-specific expression |
Q45013663 | Evidence against requirement of Ser41 and Ser45 for function of PU.1 -- molecular cloning of rat PU.1. |
Q34617317 | Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria. |
Q44480300 | Expression of RANK is dependent upon differentiation into the macrophage/osteoclast lineage: induction by 1alpha,25-dihydroxyvitamin D3 and TPA in a human myelomonocytic cell line, HL60. |
Q37153719 | Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma |
Q38334917 | Identification of a novel tumor necrosis factor alpha-responsive region in the NCF2 promoter |
Q28208097 | Identification of amino acid residues in the ETS transcription factor Erg that mediate Erg-Jun/Fos-DNA ternary complex formation |
Q40775802 | In vivo complex formation of PU.1 with HDAC1 associated with PU.1-mediated transcriptional repression |
Q37302271 | Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants |
Q39732380 | Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. |
Q42471012 | LPS activation of Toll-like receptor 4 signals CD11b/CD18 expression in neutrophils |
Q37190211 | Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages |
Q52571560 | Makorin RING finger protein 1 (MKRN1) has negative and positive effects on RNA polymerase II-dependent transcription. |
Q52572345 | Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU.1. |
Q38304270 | Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation |
Q44830496 | Multiple functional domains of the oncoproteins Spi-1/PU.1 and TLS are involved in their opposite splicing effects in erythroleukemic cells |
Q51081020 | NF-IL6 (C/EBPbeta ) vigorously activates il1b gene expression via a Spi-1 (PU.1) protein-protein tether. |
Q36941201 | NFATc2 recruits cJun homodimers to an NFAT site to synergistically activate interleukin-2 transcription |
Q24671782 | Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1 |
Q49793888 | Niche signals and transcription factors involved in tissue-resident macrophage development |
Q36138617 | PU.1 and pRB Interact and Cooperate To Repress GATA-1 and Block Erythroid Differentiation |
Q37453513 | PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis |
Q52584538 | PU.1 binding to the p53 family of tumor suppressors impairs their transcriptional activity. |
Q47282245 | Phenotypic stability and plasticity in GMP-derived cells as determined by their underlying regulatory network |
Q33707708 | Potential autoregulation of transcription factor PU.1 by an upstream regulatory element |
Q54047518 | Proteinase expression during differentiation of human osteoclasts in vitro. |
Q38180770 | Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition. |
Q36370346 | Reciprocal roles for CCAAT/enhancer binding protein (C/EBP) and PU.1 transcription factors in Langerhans cell commitment |
Q38322398 | Recruitment of nuclear factor Y to the inverted CCAAT element (ICE) by c-Jun and E1A stimulates basal transcription of the bone sialoprotein gene in osteosarcoma cells |
Q33933221 | Regulation of Ets function by protein - protein interactions |
Q24530129 | Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia |
Q36255973 | Role of transcription factors C/EBPalpha and PU.1 in normal hematopoiesis and leukemia. |
Q35182721 | SHP2 tyrosine phosphatase stimulates CEBPA gene expression to mediate cytokine-dependent granulopoiesis |
Q73104368 | SPI-1 transforming properties depend upon specifically activated forms of the EPOR |
Q24676215 | Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells |
Q35195611 | Selection and characterization of a DNA aptamer that can discriminate between cJun/cJun and cJun/cFos |
Q33772497 | Ski can negatively regulates macrophage differentiation through its interaction with PU.1. |
Q40424959 | Subversion of T lineage commitment by PU.1 in a clonal cell line system |
Q41991525 | Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication. |
Q35012089 | T-lineage specification and commitment: a gene regulation perspective |
Q60915997 | Targeting JNK pathway promotes human hematopoietic stem cell expansion |
Q33883575 | The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication |
Q36247415 | The Janus-faced Nature of miR-22 in Hematopoiesis: Is It an Oncogenic Tumor Suppressor or Rather a Tumor-Suppressive Oncogene? |
Q36129863 | The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia |
Q47118296 | The evolution of the macrophage-specific enhancer (Fms intronic regulatory element) within the CSF1R locus of vertebrates |
Q47659569 | The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner |
Q37762444 | The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis |
Q111441839 | The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination |
Q24338577 | The transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interaction |
Q42813362 | Transcription factor PU.1 is expressed in white adipose and inhibits adipocyte differentiation |
Q36970209 | Transcriptional control of granulocyte and monocyte development |
Q44559401 | Transcriptional regulation of CHI3L1, a marker gene for late stages of macrophage differentiation. |
Q34658545 | Transcriptional regulation of granulocyte and monocyte development |
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Q40703225 | Transfection of embryonal carcinoma cells at high efficiency using liposome-mediated transfection |
Q34123332 | When Ets transcription factors meet their partners |
Q37644767 | Zbtb1 prevents default myeloid differentiation of lymphoid-primed multipotent progenitors |
Q39676079 | c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription. |
Q40274276 | c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation |
Q42257522 | c-Jun homodimers can function as a context-specific coactivator |
Q37969687 | c-Jun, at the crossroad of the signaling network |
Q34464525 | c-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter |
Q38977030 | hnRNP K in PU.1-containing complexes recruited at the CD11b promoter: a distinct role in modulating granulocytic and monocytic differentiation of AML-derived cells. |
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