c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.

scientific article

c-Jun is a JNK-independent coactivator of the PU.1 transcription factor. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.274.8.4939
P698PubMed publication ID9988737

P50authorRoger John DavisQ21165803
Alan J WhitmarshQ42533967
Daniel G TenenQ44797022
P2093author name stringC L Carpenter
T Hoang
D E Zhang
G Behre
M P Coghlan
P2860cites workJNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domainQ24308838
Ras-related proteins in signal transduction and growth controlQ24324056
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1Q24339633
The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIBQ24563487
Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cellsQ24610231
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1Q28114883
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogeneQ28116777
Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op MiceQ28593712
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2Q28609817
Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1Q33774804
Normal myeloid development requires both the glutamine-rich transactivation domain and the PEST region of transcription factor PU.1 but not the potent acidic transactivation domainQ33775074
Inhibition of hematopoiesis by competitive binding of transcription factor PU.1.Q35673096
PU.1 can participate in an active enhancer complex without its transcriptional activation domainQ35902741
Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.Q36364154
CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoterQ36557608
Cellular transformation and malignancy induced by ras require c-junQ36561672
Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signalingQ36566543
Cell-specific expression of the macrophage scavenger receptor gene is dependent on PU.1 and a composite AP-1/ets motifQ36656291
Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)Q36671577
Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cellsQ36689171
Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteinsQ36790397
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.Q36792845
PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activityQ36809426
Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes.Q38316909
Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activationQ38320946
The transcription factor PU.1 is involved in macrophage proliferationQ38356001
Serum response factor mediates AP-1-dependent induction of the skeletal alpha-actin promoter in ventricular myocytesQ38357989
Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalphaQ39724224
Activation of transcription by PU.1 requires both acidic and glutamine domainsQ40018093
The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU.1 and c-JunQ41056192
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.Q41205566
c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK.Q41442860
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptorQ41497311
The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascadesQ41688659
Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotidesQ41962689
Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiationQ42736547
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73Q42825163
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.Q52214235
A growing coactivator networkQ59080836
P433issue8
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)4939-4946
P577publication date1999-02-01
P1433published inJournal of Biological ChemistryQ867727
P1476titlec-Jun is a JNK-independent coactivator of the PU.1 transcription factor
P478volume274

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cites work (P2860)
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