scholarly article | Q13442814 |
P356 | DOI | 10.1182/BLOOD-2011-12-397083 |
P8608 | Fatcat ID | release_ztcwijkq7jdkpb2pjxntmcd4rm |
P953 | full work available at URL | http://ashpublications.org/blood/article-pdf/120/10/2064/1357117/zh803612002064.pdf |
http://www.bloodjournal.org/content/bloodjournal/120/10/2064.full.pdf | ||
P698 | PubMed publication ID | 22786876 |
P5875 | ResearchGate publication ID | 229075190 |
P50 | author | Marry M. van den Heuvel-Eibrink | Q71498972 |
Jan Trka | Q88547666 | ||
Vincent H J van der Velden | Q89748267 | ||
Dirk Reinhardt | Q91648795 | ||
P2093 | author name string | Andre Baruchel | |
Valérie de Haas | |||
Maaike Luesink | |||
C. Michel Zwaan | |||
Joop H. Jansen | |||
Bert A. van der Reijden | |||
Iris H. I M. Hollink | |||
Jan B. M. Boezeman | |||
Ruth H. J N. Knops | |||
P2860 | cites work | Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1 | Q24671782 |
Redirecting differentiation of hematopoietic progenitors by a transcription factor, GATA-2 | Q28509425 | ||
Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors | Q28591446 | ||
An early haematopoietic defect in mice lacking the transcription factor GATA-2 | Q28593072 | ||
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. | Q30368393 | ||
High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle | Q33402840 | ||
GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors | Q34089261 | ||
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. | Q34192317 | ||
Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis | Q34219129 | ||
Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia | Q34313643 | ||
Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. | Q34365985 | ||
Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia | Q34542996 | ||
Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia | Q34612599 | ||
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia | Q34627568 | ||
Biology, risk stratification, and therapy of pediatric acute leukemias: an update | Q34764504 | ||
Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology Group | Q35046171 | ||
Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene | Q35095712 | ||
Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia | Q35249294 | ||
Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia | Q35265916 | ||
Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature | Q35750366 | ||
Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival. | Q36006394 | ||
Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia | Q36883073 | ||
Pediatric acute myeloid leukemia: towards high-quality cure of all patients | Q37007119 | ||
Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate | Q37291657 | ||
GATA-2 reinforces megakaryocyte development in the absence of GATA-1 | Q37334070 | ||
Assessment of minimal residual disease in acute myeloid leukemia | Q37784128 | ||
The role of the GATA2 transcription factor in normal and malignant hematopoiesis | Q37878679 | ||
The transcriptional program of terminal granulocytic differentiation | Q38334911 | ||
EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia | Q38345216 | ||
Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay | Q42032841 | ||
Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression | Q43806498 | ||
Abnormal WT1 expression in the CD34-negative compartment in myelodysplastic bone marrow | Q44117292 | ||
Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities. | Q44666362 | ||
Differential gene expression in human hematopoietic stem cells specified toward erythroid, megakaryocytic, and granulocytic lineage | Q50894639 | ||
GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism | Q51756149 | ||
Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique. | Q54436758 | ||
Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: a European LeukemiaNet study. | Q54465378 | ||
High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia. | Q54611165 | ||
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome) | Q55671562 | ||
High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome | Q58492940 | ||
Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia | Q60602807 | ||
Hematologic malignancies | Q74523586 | ||
Feasibility of using the combined MDS-EVI1/EVI1 gene expression as an alternative molecular marker in acute myeloid leukemia: a report of four cases | Q80784426 | ||
Marked genetic heterogeneity in familial myelodysplasia/acute myeloid leukaemia | Q83990685 | ||
No prognostic impact of the WT1 gene single nucleotide polymorphism rs16754 in pediatric acute myeloid leukemia | Q84579865 | ||
Clinical significance of flowcytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol | Q84612087 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | gene expression | Q26972 |
leukemia | Q29496 | ||
P304 | page(s) | 2064-2075 | |
P577 | publication date | 2012-07-11 | |
P1433 | published in | Blood | Q885070 |
P1476 | title | High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia | |
P478 | volume | 120 |
Q46571589 | Bone marrow WT1 levels at diagnosis, post-induction and post-intensification in adult de novo AML. |
Q64112901 | CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1 |
Q91212027 | CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex |
Q36276945 | Cis-regulatory mechanisms governing stem and progenitor cell transitions |
Q64114169 | Diagnosis of fusion genes using targeted RNA sequencing |
Q52597254 | Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes |
Q35626111 | Epigenetic Determinants of Erythropoiesis: Role of the Histone Methyltransferase SetD8 in Promoting Erythroid Cell Maturation and Survival |
Q53257803 | Expression and prognostic significance of GATA-binding protein 2 in colorectal cancer |
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Q90605249 | GATA2 +9.5 enhancer: from principles of hematopoiesis to genetic diagnosis in precision medicine |
Q36257547 | GATA2 Inhibition Sensitizes Acute Myeloid Leukemia Cells to Chemotherapy |
Q50482088 | GATA2 mutations in sporadic and familial acute myeloid leukaemia patients with CEBPA mutations |
Q42371607 | GATA2 regulates the erythropoietin receptor in t(12;21) ALL. |
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Q37226744 | Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia |
Q35535835 | Haematopoietic and immune defects associated with GATA2 mutation |
Q26828941 | Heritable GATA2 mutations associated with familial AML-MDS: a case report and review of literature |
Q37298691 | High expression of MAP7 predicts adverse prognosis in young patients with cytogenetically normal acute myeloid leukemia |
Q35677697 | Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma. |
Q57465846 | Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene |
Q92757626 | Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells |
Q34343246 | Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA-2 |
Q53316112 | Mutations of the GATA2 and CEBPA genes in paediatric acute myeloid leukaemia |
Q33759034 | RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML. |
Q64058095 | Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis |
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