| scholarly article | Q13442814 |
| P50 | author | Manoj Raghavan | Q56432956 |
| Peter N Cockerill | Q56432958 | ||
| Constanze Bonifer | Q59556203 | ||
| P2093 | author name string | Anetta Ptasinska | |
| Pierre Cauchy | |||
| Olaf Heidenreich | |||
| Maria Rosaria Imperato | |||
| Salam A Assi | |||
| H Ruud Delwel | |||
| Justin Loke | |||
| Natalia Martinez Soria | |||
| Yura Grabovska | |||
| P2860 | cites work | Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions | Q24318843 |
| Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia | Q24596770 | ||
| Identification and characterization of Hoxa9 binding sites in hematopoietic cells | Q24610737 | ||
| Regulation of myeloid leukaemia by the cell-fate determinant Musashi | Q24634359 | ||
| AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation | Q24681049 | ||
| The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells | Q24800256 | ||
| A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis | Q27678844 | ||
| Genomic Classification and Prognosis in Acute Myeloid Leukemia | Q27853389 | ||
| Molecular classification of cancer: class discovery and class prediction by gene expression monitoring | Q27861072 | ||
| Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets | Q28082027 | ||
| Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study | Q28139696 | ||
| Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt | Q28189555 | ||
| Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461) | Q28209814 | ||
| Cooperation of BCR-ABL and AML1/MDS1/EVI1 in blocking myeloid differentiation and rapid induction of an acute myelogenous leukemia | Q28214984 | ||
| Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos | Q28252704 | ||
| Cooperation between C/EBPalpha TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation | Q28580573 | ||
| Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia | Q29615735 | ||
| Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data | Q30670345 | ||
| Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b | Q33889059 | ||
| The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice | Q33895709 | ||
| AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations | Q33943238 | ||
| Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1. | Q34360766 | ||
| A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia | Q34413730 | ||
| Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia | Q34796524 | ||
| Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations | Q35210567 | ||
| Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors | Q35750824 | ||
| Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal | Q35806108 | ||
| Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia. | Q35954771 | ||
| Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding. | Q36166902 | ||
| Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukaemia | Q87053502 | ||
| AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency | Q36371457 | ||
| ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia | Q36395611 | ||
| Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias | Q36550719 | ||
| Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA. | Q36690799 | ||
| Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein | Q36692472 | ||
| Human AML1/MDS1/EVI1 fusion protein induces an acute myelogenous leukemia (AML) in mice: a model for human AML | Q37116614 | ||
| HOX expression patterns identify a common signature for favorable AML. | Q37176769 | ||
| An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation | Q37299008 | ||
| Extending dimerization interfaces: the bZIP basic region can form a coiled coil. | Q37624408 | ||
| Gene regulatory networks governing haematopoietic stem cell development and identity | Q37780167 | ||
| A highly conserved c-fms gene intronic element controls macrophage-specific and regulated expression | Q38294949 | ||
| siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts. | Q38313725 | ||
| Addiction of t(8;21) and inv(16) acute myeloid leukemia to native RUNX1. | Q39093568 | ||
| High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia | Q39587664 | ||
| Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells. | Q39953712 | ||
| Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature. | Q41089332 | ||
| Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias | Q41709128 | ||
| Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model | Q41916176 | ||
| Developmental-stage-dependent transcriptional response to leukaemic oncogene expression. | Q42602670 | ||
| EVI-1 zinc finger protein works as a transcriptional activator via binding to a consensus sequence of GACAAGATAAGATAAN1-28 CTCATCTTC. | Q42827546 | ||
| Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. | Q43102402 | ||
| Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia | Q43499854 | ||
| Delineating MEIS1 cis-regulatory elements active in hematopoietic cells | Q44137334 | ||
| AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells | Q44248072 | ||
| In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia | Q46139535 | ||
| t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia | Q46916122 | ||
| MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome. | Q51681219 | ||
| Stem cell gene expression programs influence clinical outcome in human leukemia. | Q51856192 | ||
| Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors. | Q52187583 | ||
| Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. | Q52524249 | ||
| RUNX1/EVI1, which blocks myeloid differentiation, inhibits CCAAT-enhancer binding protein alpha function. | Q52582395 | ||
| Frequent EVI1 translocations in myeloid blast crisis CML that evolves through tyrosine kinase inhibitors. | Q53282573 | ||
| Regulation of the PU.1 gene by distal elements | Q57615588 | ||
| Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia | Q68774986 | ||
| Development of megakaryoblastic leukaemia in Runx1-Evi1 knock-in chimaeric mouse | Q83948543 | ||
| Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia | Q84596053 | ||
| P433 | issue | 8 | |
| P304 | page(s) | 1654-1668 | |
| P577 | publication date | 2017-05-01 | |
| P1433 | published in | Cell Reports | Q5058165 |
| P1476 | title | RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML. | |
| P478 | volume | 19 |
| Q48721287 | A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program |
| Q87757676 | C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia |
| Q64076648 | Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity |
| Q89900676 | High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia |
| Q48579835 | Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia. |
| Q58604425 | Pharmacological inhibition of aberrant transcription factor complexes in inversion 16 acute myeloid leukemia |
| Q42362636 | RUNX oncoproteins and miRNA networks |
| Q61801952 | RUNX1 mutations enhance self-renewal and block granulocytic differentiation in human in vitro models and primary AMLs |
| Q90162763 | RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction |
| Q90053632 | Role of GFI1 in Epigenetic Regulation of MDS and AML Pathogenesis: Mechanisms and Therapeutic Implications |
| Q64911185 | Subtype-specific regulatory network rewiring in acute myeloid leukemia. |
| Q92337654 | Transcriptional networks in acute myeloid leukemia |
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