Loss of HLTF function promotes intestinal carcinogenesis

scientific article published on 27 March 2012

Loss of HLTF function promotes intestinal carcinogenesis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1027753240
P356DOI10.1186/1476-4598-11-18
P932PMC publication ID3337324
P698PubMed publication ID22452792
P5875ResearchGate publication ID221977792

P2093author name stringXiaoli Wu
Hao Ding
Sabine Mai
Mojgan Rastegar
Sam Kung
Sumit Sandhu
Zinnatun Nabi
P2860cites workCloning of an SNF2/SWI2-related protein that binds specifically to the SPH motifs of the SV40 enhancer and to the HIV-1 promoterQ24315927
HLTF gene silencing in human colon cancerQ24536137
The role of chromosomal instability in tumor initiationQ24541508
Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forksQ24642282
Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitinationQ24652076
A genetic model for colorectal tumorigenesisQ27860582
Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like proteinQ28587423
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC geneQ29616490
Genetic instability in colorectal cancersQ29618711
Microsatellite instability in cancer of the proximal colonQ29620692
SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesisQ29871514
Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future ratesQ30538531
MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapyQ33497321
A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ miceQ33556956
Role of double-stranded DNA translocase activity of human HLTF in replication of damaged DNAQ33614018
Genomic and epigenetic instability in colorectal cancer pathogenesisQ33836026
Adenomatous polyposis coli protein regulates the cellular response to DNA replication stressQ33929860
Coordinated protein and DNA remodeling by human HLTF on stalled replication forkQ33973384
Intestinal adenomas can develop with a stable karyotype and stable microsatellitesQ34066329
Role of yeast Rad5 and its human orthologs, HLTF and SHPRH in DNA damage toleranceQ34094363
Inactivation of helicase-like transcription factor by promoter hypermethylation in human gastric cancer.Q34199910
DNA hypermethylation and histone hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinomaQ34220062
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouseQ34344768
Characterization of a helicase-like transcription factor involved in the expression of the human plasminogen activator inhibitor-1 geneQ34385798
Developmental regulation of Zbu1, a DNA-binding member of the SWI2/SNF2 familyQ34423818
Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instabilityQ34775052
Pathology of mouse models of intestinal cancer: consensus report and recommendationsQ35075841
Generation of a mouse model for studying the role of upregulated RTEL1 activity in tumorigenesisQ36205393
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.Q36213486
The checkpoint response to replication stressQ37501718
DNA methylation markers in colorectal cancerQ37687919
Maintaining genome stability at the replication forkQ37696954
Cytogenetic characterization of two colon cell lines by using conventional G-banding, comparative genomic hybridization, and whole chromosome paintingQ38495887
Quantitative detection of promoter hypermethylation in multiple genes in the serum of patients with colorectal cancer.Q46718275
Cloning, characterization, and steroid-dependent posttranscriptional processing of RUSH-1 alpha and beta, two uteroglobin promoter-binding proteinsQ48058368
Generation of conditional knockout alleles for PDGF-C.Q50887587
Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence.Q51771364
DNA-dependent adenosine triphosphatase (helicaselike transcription factor) activates beta-globin transcription in K562 cells.Q52126123
Promoter methylation of helicase-like transcription factor is associated with the early stages of gastric cancer with family history.Q53348996
Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.Q53364696
The significance of unstable chromosomes in colorectal cancer.Q53376250
Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.Q53399373
Highly-methylated colorectal cancers show poorly-differentiated phenotype.Q54564453
The structural nature of chromosomal instability in colon cancer cellsQ58109841
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instabilityQ72127255
Methylation of serum DNA is an independent prognostic marker in colorectal cancerQ79451531
CpG island methylator phenotype in cancerQ81080870
Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivationQ81454513
Molecular Genetics of Colorectal CancerQ82521439
CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancerQ83365535
P921main subjectcarcinogenesisQ1637543
P304page(s)18
P577publication date2012-03-27
P1433published inMolecular CancerQ15724585
P1476titleLoss of HLTF function promotes intestinal carcinogenesis
P478volume11

Reverse relations

cites work (P2860)
Q35268479Alterations of DNA repair genes in the NCI-60 cell lines and their predictive value for anticancer drug activity.
Q34460069Cellular commitment in the developing cerebellum
Q33611481Circulating cell-free methylated DNA and lactate dehydrogenase release in colorectal cancer
Q47735296Functions of SMARCAL1, ZRANB3, and HLTF in maintaining genome stability
Q36904912HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages
Q35762843HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.
Q92956640Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice
Q27301898Helicase-like transcription factor (Hltf) regulates G2/M transition, Wt1/Gata4/Hif-1a cardiac transcription networks, and collagen biogenesis
Q52719002Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC).
Q30434300Helicase-like transcription factor: a new marker of well-differentiated thyroid cancers
Q36672248Heterogeneous DNA methylation contributes to tumorigenesis through inducing the loss of coexpression connectivity in colorectal cancer
Q38866681Homologous recombination maintenance of genome integrity during DNA damage tolerance
Q29871515Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.
Q38301131MicroRNA-145 contributes to enhancing radiosensitivity of cervical cancer cells
Q34796010Role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain
Q38893314The Role of Stem Cell DNA Methylation in Colorectal Carcinogenesis
Q38608560The helicase-like transcription factor (HLTF) in cancer: loss of function or oncomorphic conversion of a tumor suppressor?

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