Immunohistochemistry and microsatellite instability analysis in molecular subtyping of colorectal carcinoma based on mismatch repair competency

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Immunohistochemistry and microsatellite instability analysis in molecular subtyping of colorectal carcinoma based on mismatch repair competency is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4723875
P698PubMed publication ID26885030

P2093author name stringLin Yuan
Xiaoyan Zhou
Ping Wei
Yayun Chi
Xiaochen Chen
Weiqi Sheng
Daren Shi
Weixiang Chen
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
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hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6Q24323176
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Value of pedigree/clinical data, immunohistochemistry and microsatellite instability analyses in reducing the cost of determining hMLH1 and hMSH2 gene mutations in patients with colorectal cancerQ30588580
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Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family historyQ33910331
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Histopathological identification of colon cancer with microsatellite instabilityQ35746344
Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesisQ35747184
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Extensive molecular screening for hereditary non-polyposis colorectal cancerQ36641429
Classification of colorectal cancer based on correlation of clinical, morphological and molecular featuresQ36699559
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Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.Q37157691
CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancerQ37185561
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Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variantQ37360286
A two-antibody mismatch repair protein immunohistochemistry screening approach for colorectal carcinomas, skin sebaceous tumors, and gynecologic tract carcinomasQ37866075
Complementation of an hMSH2 defect in human colorectal carcinoma cells by human chromosome 2 transferQ38307828
Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing.Q38360916
Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancerQ38449001
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Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6.Q41086058
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutationQ41448577
Molecular biology of colorectal cancerQ41686589
Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repairQ42134566
Morphology of sporadic colorectal cancer with DNA replication errorsQ43087650
Mucinous carcinoma of the colon: correlation of loss of mismatch repair enzymes with clinicopathologic features and survivalQ43778696
Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancerQ44605110
The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative studyQ44628695
Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancerQ47209748
Colorectal carcinoma survival among hereditary nonpolyposis colorectal carcinoma family members.Q53353136
Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression.Q53439660
Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter.Q54596227
MSI-low, a real phenomenon which varies in frequency among cancer types.Q54745600
Colorectal cancerQ57191694
Low-level microsatellite instability in most colorectal carcinomasQ57240042
Use of Molecular Tumor Characteristics to Prioritize Mismatch Repair Gene Testing in Early-Onset Colorectal CancerQ57265834
Prognosis of colorectal cancer varies in different high-risk conditionsQ58264884
Hereditary colorectal cancerQ73088287
Phenotype of microsatellite unstable colorectal carcinomas: Well-differentiated and focally mucinous tumors and the absence of dirty necrosis correlate with microsatellite instabilityQ73322611
Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinomaQ74046178
Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer familiesQ74309292
Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumorsQ77639637
Histopathology and Mismatch Repair Status of 458 Consecutive Colorectal CarcinomasQ79203530
Value of histopathology in predicting microsatellite instability in hereditary nonpolyposis colorectal cancer and sporadic colorectal cancerQ79203534
Clinicopathologic factors identify sporadic mismatch repair-defective colon cancersQ80522940
Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancerQ80557773
Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasmsQ81186123
Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 stainingQ81333266
Molecular Genetics of Colorectal CancerQ82521439
Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panelQ84452748
Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinomaQ84570529
P433issue11
P921main subjectmicrosatelliteQ265193
immunohistochemistryQ899285
DNA mismatch repairQ2984243
colorectal carcinomaQ25493920
P304page(s)20988-21000
P577publication date2015-11-15
P1433published inInternational Journal of Clinical and Experimental MedicineQ6051338
P1476titleImmunohistochemistry and microsatellite instability analysis in molecular subtyping of colorectal carcinoma based on mismatch repair competency
P478volume8

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