Epigenetics and colorectal cancer

scientific article

Epigenetics and colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NRGASTRO.2011.173
P932PMC publication ID3391545
P698PubMed publication ID22009203
P5875ResearchGate publication ID51727019

P2093author name stringWilliam M Grady
Victoria Valinluck Lao
P2860cites workDNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian developmentQ22010765
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase geneQ22011158
DNA methylation patterns and epigenetic memoryQ22065780
MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinomaQ24315119
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instabilityQ24319995
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3BQ24564757
CpG island methylation in colorectal cancer: past, present and futureQ24597977
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblastsQ24629646
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shoresQ24649374
CpG island methylator phenotype in colorectal cancerQ24672170
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancersQ24679642
5-halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2).Q24794741
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agentsQ27777800
A genetic model for colorectal tumorigenesisQ27860582
The consensus coding sequences of human breast and colorectal cancersQ27861035
CpG islands in vertebrate genomesQ27861045
The genomic landscapes of human breast and colorectal cancersQ27861078
The genetics of the p53 pathway, apoptosis and cancer therapyQ27863460
Role of histone H3 lysine 27 methylation in Polycomb-group silencingQ28131795
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancerQ28251800
The cancer epigenome--components and functional correlatesQ28278109
Genetic alterations during colorectal-tumor developmentQ28281200
CpG islands and the regulation of transcriptionQ28315762
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genesQ28508338
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancerQ29614277
Epigenetic activation of tumor suppressor microRNAs in human cancer cellsQ36609070
PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.Q36661711
Classification of colorectal cancer based on correlation of clinical, morphological and molecular featuresQ36699559
Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of dietQ36741945
Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosaQ36755132
Epigenetics and aging: the targets and the marksQ36845462
Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancersQ36851776
Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.Q36922505
Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia.Q36988762
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.Q37070832
Epigenetic gene regulation in cancerQ37087598
A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancerQ37090752
A multifactorial signature of DNA sequence and polycomb binding predicts aberrant CpG island methylationQ37122031
DNA methylation patterns in lung carcinomasQ37188534
Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization.Q37229718
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.Q37262433
Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients: is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?Q37353936
Serrated polyps and colorectal cancer: new pathway to malignancyQ37463062
DNA methylation markers in colorectal cancerQ37687919
Cancer screening in the United States, 2010: a review of current American Cancer Society guidelines and issues in cancer screeningQ37708994
Histone modifications and cancerQ37797690
Cancer statistics, 2006Q29615133
Epigenetics in cancerQ29617139
DNA methylation landscapes: provocative insights from epigenomicsQ29617144
The history of cancer epigeneticsQ29617273
The DNA methyltransferases of mammalsQ29617317
Hypomethylation distinguishes genes of some human cancers from their normal counterpartsQ29619217
Epigenetic stem cell signature in cancerQ29622897
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancerQ29622925
Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanismsQ30946240
Proteomic analysis reveals field-wide changes in protein expression in the morphologically normal mucosa of patients with colorectal neoplasiaQ33248743
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencingQ33268624
LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instabilityQ33283510
Comparing the DNA hypermethylome with gene mutations in human colorectal cancerQ33300134
Expression of the hMLH1 gene is a possible predictor for the clinical response to 5-fluorouracil after a surgical resection in colorectal cancerQ33337155
DNA methylation and chromatin structure: the puzzling CpG islandsQ33340586
Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sampleQ33383866
DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer.Q33517453
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profilingQ33520213
Three DNA methylation epigenotypes in human colorectal cancerQ33520394
VEZF1 elements mediate protection from DNA methylationQ33523011
Stool DNA and occult blood testing for screen detection of colorectal neoplasiaQ33594565
DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids.Q33634174
Sensitive digital quantification of DNA methylation in clinical samplesQ33761814
CpG island methylator phenotypes in aging and cancer.Q33765672
Sessile serrated adenomas and classical adenomas: an epigenetic perspective on premalignant neoplastic lesions of the gastrointestinal tract.Q33770826
Genomic and epigenetic instability in colorectal cancer pathogenesisQ33836026
DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancerQ33837632
Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumorQ33867627
Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP).Q33869180
LINE-1 hypomethylation during primary colon cancer progressionQ33886421
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.Q33888431
Dietary folate, alcohol and B vitamins in relation to LINE-1 hypomethylation in colon cancerQ33954716
Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric originQ33968610
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.Q33979536
Aging, methylation and cancerQ34016971
Cigarette smoking and colorectal cancer risk by molecularly defined subtypesQ34042268
Aberrant epigenetic landscape in cancer: how cellular identity goes awryQ34149629
Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypesQ37821085
Colorectal cancer epigenetics: complex simplicityQ37827277
CpG methylation inhibits binding of several sequence-specific DNA-binding proteins from pea, wheat, soybean and cauliflowerQ38334537
Genome-wide quantitative assessment of variation in DNA methylation patternsQ39600841
Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1.Q39688414
Comparative analysis of PCR-based biomarker assay methods for colorectal polyp detection from fecal DNA.Q39835466
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLightQ39853397
Gene body-specific methylation on the active X chromosomeQ40166744
GSTP1 hypermethylation as a molecular marker in the diagnosis of prostatic cancer: is there a correlation with clinical stage, Gleason grade, PSA value or age?Q40471558
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblastsQ40623261
P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53.Q40667147
The role of DNA mismatch repair in platinum drug resistanceQ41155820
Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 casesQ43735744
Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expressionQ43796904
Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based studyQ44552941
Effect of calcium supplementation on the risk of large bowel polypsQ44938210
Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancerQ46578998
Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damageQ46846179
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instabilityQ47704165
Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas.Q47783677
The American College of Gastroenterology Emily Couric Lecture--the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived?Q48540832
Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers.Q51603737
Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation.Q51772302
DNA motifs associated with aberrant CpG island methylation.Q51949819
Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.Q53346861
Improved fecal DNA test for colorectal cancer screening.Q54567825
Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.Q54568648
A distinct DNA methylation profile associated with microsatellite and chromosomal stable sporadic colorectal cancers.Q54599567
Suppression of intestinal neoplasia by DNA hypomethylation.Q54613769
Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene.Q54650748
Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions.Q54794231
Profound Flanking Sequence Preference of Dnmt3a and Dnmt3b Mammalian DNA Methyltransferases Shape the Human EpigenomeQ57267655
Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancerQ57591268
Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progressionQ58613225
Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequenceQ61709335
DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifsQ64128252
Field effect of human colon carcinoma on normal mucosa: relevance of carcinoembryonic antigen expressionQ71593229
DNA methylation decreases in aging but not in immortal cellsQ71718599
Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencingQ71729092
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomasQ71804951
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colonQ72781919
Increased cytosine DNA-methyltransferase activity during colon cancer progressionQ72832112
Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylationQ73263458
Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2Q78532732
CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinomaQ79988265
Sessile serrated adenoma (SSA) vs. traditional serrated adenoma (TSA)Q80418165
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in miceQ81441297
Redundant DNA methylation in colorectal cancers of Lynch-syndrome patientsQ81622997
Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancerQ36606069
A simplified, noninvasive stool DNA test for colorectal cancer detectionQ81900521
Molecular Genetics of Colorectal CancerQ82521439
CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancerQ83365535
Clinicopathological and molecular features of colorectal serrated neoplasias with different mucosal crypt patternsQ83684001
Methylation status of normal background mucosa is correlated with occurrence and development of neoplasia in the distal colonQ84520702
Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomasQ34170505
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.Q34184707
Mutation and cancer: a model for Wilms' tumor of the kidneyQ34207334
Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancerQ34358286
Co-evolution of X-chromosome inactivation and imprinting in mammalsQ34409829
Colorectal cancer molecular biology moves into clinical practiceQ34425013
MGMT promoter methylation and field defect in sporadic colorectal cancer.Q34452509
Serrated pathway and APC (conventional)-type colorectal polyps: molecular-morphologic correlations, genetic pathways, and implications for classificationQ34564921
Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumorsQ34573834
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.Q34574880
Altered methylation patterns in cancer cell genomes: cause or consequence?Q34710435
Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancerQ34748786
DNA methylation in cancer: too much, but also too littleQ34770545
5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer.Q34777582
Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancerQ34876473
DNA methylation predicts recurrence from resected stage III proximal colon cancerQ35051119
Cancer epigenetics: linking basic biology to clinical medicine.Q35348043
A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instabilityQ35594520
Genome-scale analysis of aberrant DNA methylation in colorectal cancerQ35694387
CpG island methylation in colorectal adenomasQ35746792
CpG island methylation in aberrant crypt foci of the colorectumQ35748049
CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studiesQ35760749
CpG methylation as a mechanism for the regulation of E2F activityQ35776918
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinomaQ35807817
CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutationsQ35807863
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2Q35848528
Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sampleQ35855515
The epigenetics of cancer etiologyQ35920461
Biochemistry and biology of mammalian DNA methyltransferasesQ35939026
Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasisQ36175129
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer.Q36276940
Molecular classification and correlates in colorectal cancerQ36329300
Concordant DNA methylation in synchronous colorectal carcinomas.Q36529752
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)686-700
P577publication date2011-10-18
P1433published inNature Reviews Gastroenterology & HepatologyQ2108255
P1476titleEpigenetics and colorectal cancer
P478volume8

Reverse relations

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Q33597778Integrating genetic and genomic information into effective cancer care in diverse populations
Q36463854Integration of molecular pathology, epidemiology and social science for global precision medicine
Q50043586Integrative analysis of exogenous, endogenous, tumour and immune factors for precision medicine
Q90640128Investigation of the Genome-Wide Genetic and Epigenetic Networks for Drug Discovery Based on Systems Biology Approaches in Colorectal Cancer
Q64110806JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer
Q52597337KDM4B promotes DNA damage response via STAT3 signaling and is a target of CREB in colorectal cancer cells.
Q35227430KeyPathwayMiner 4.0: condition-specific pathway analysis by combining multiple omics studies and networks with Cytoscape.
Q34661887Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population
Q99708802Landscape of Genome-Wide DNA Methylation of Colorectal Cancer Metastasis
Q38194035Long non-coding RNAs in colorectal cancer: implications for pathogenesis and clinical application
Q36194410Long-lasting reduction in clonogenic potential of colorectal cancer cells by sequential treatments with 5-azanucleosides and topoisomerase inhibitors.
Q37376407MECP2 promotes the growth of gastric cancer cells by suppressing miR-338-mediated antiproliferative effect
Q64955692Mechanism of Apoptosis Induced by Curcumin in Colorectal Cancer.
Q36323781Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence
Q40522662MiR-339 and especially miR-766 reactivate the expression of tumor suppressor genes in colorectal cancer cell lines through DNA methyltransferase 3B gene inhibition.
Q99239609MicroRNA-421 Inhibits Apoptosis by Downregulating Caspase-3 in Human Colorectal Cancer
Q37075412Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication
Q34485631Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage.
Q39308037Molecular biomarkers for an early diagnosis, effective treatment and prognosis of colorectal cancer: Current updates
Q27002450Molecular biomarkers for the detection of metastatic colorectal cancer cells
Q27010063Molecular markers for colorectal cancer screening
Q24289344Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease
Q64101405Mucinous colorectal adenocarcinoma: clinical pathology and treatment options
Q37148924Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in oligodendroglial tumors.
Q98159009Multitarget stool DNA test compared with fecal occult blood test for colorectal cancer screening
Q39306327New insights into the earliest stages of colorectal tumorigenesis
Q36059870No evidence for interference of h&e staining in DNA testing: usefulness of DNA extraction from H&E-stained archival tissue sections.
Q36238964Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration
Q38114502Novel drug discovery opportunities for colorectal cancer
Q36610385Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa
Q95725436O6-Methyguanine-DNA Methyl Transferase (MGMT) Promoter Methylation in Serum DNA of Iranian Patients with Colorectal Cancer
Q37074078Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.
Q34296789Ogino et Al. Respond to "the 21st century epidemiologist".
Q61632631Overcoming Drug Resistance in Colorectal Cancer by MicroRNAs
Q33767601PCDH18 is frequently inactivated by promoter methylation in colorectal cancer
Q36546764PRIMA-1met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms
Q36926941Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer
Q92482187Polyunsaturated fatty acids and DNA methylation in colorectal cancer
Q91529267Positive expression of basic transcription factor 3 predicts poor survival of colorectal cancer patients: possible mechanisms involved
Q91756140Potential proapoptotic phytochemical agents for the treatment and prevention of colorectal cancer
Q37360360Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial.
Q35729861Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803
Q34475686Proceedings of the second international molecular pathological epidemiology (MPE) meeting
Q90319523Prognostic and Predictive Epigenetic Biomarkers in Oncology
Q36220792Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer
Q38321611Prognostic value of MGMT methylation in colorectal cancer: a meta-analysis and literature review
Q34016833Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions
Q37000981Promoter hypermethylation and downregulation of the FAS gene may be involved in colorectal carcinogenesis
Q35138892Promoter hypermethylation of tumour suppressor genes as potential biomarkers in colorectal cancer
Q56519160Promoter methylation of the RASSF1A gene may contribute to colorectal cancer susceptibility: a meta-analysis of cohort studies
Q34762217Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence.
Q36535688Prospective study of family history and colorectal cancer risk by tumor LINE-1 methylation level
Q89591419Protein Kinase A Inhibitor H89 Attenuates Experimental Proliferative Vitreoretinopathy
Q38194582Proteomics, genomics and transcriptomics: their emerging roles in the discovery and validation of colorectal cancer biomarkers
Q40413351Quantitative proteomic profiling of paired cancerous and normal colon epithelial cells isolated freshly from colorectal cancer patients.
Q38687680RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis
Q92053513Role of DNA Methylation in the Development and Differentiation of Intestinal Epithelial Cells and Smooth Muscle Cells
Q64974753Role of epigenetics in transformation of inflammation into colorectal cancer.
Q42353627Role of tissue microenvironment resident adipocytes in colon cancer
Q35040035S100P, a calcium-binding protein, is preferentially associated with the growth of polypoid tumors in colorectal cancer
Q34458644SMO expression in colorectal cancer: associations with clinical, pathological, and molecular features
Q26751035Serrated colorectal cancer: Molecular classification, prognosis, and response to chemotherapy
Q47797356Significance of histone methyltransferase SETDB1 expression in colon adenocarcinoma
Q92654720Silencing of synaptotagmin 13 inhibits tumor growth through suppressing proliferation and promoting apoptosis of colorectal cancer cells
Q37603495Silencing speckle-type POZ protein by promoter hypermethylation decreases cell apoptosis through upregulating Hedgehog signaling pathway in colorectal cancer
Q64108499Small non-coding RNA and colorectal cancer
Q99241205Stabilization of oncogenic transcripts by the IGF2BP3/ELAVL1 complex promotes tumorigenicity in colorectal cancer
Q38954637Study of apoptosis-related interactions in colorectal cancer
Q92255186Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor-An Opportunity for Cancer Treatment
Q92738272TFF3 and TFF1 expression levels are elevated in colorectal cancer and promote the malignant behavior of colon cancer by activating the EMT process
Q39471157Tailoring gut immune responses with lipoteichoic acid-deficient Lactobacillus acidophilus
Q27027266Targeting aberrant colon cancer-specific DNA methylation with lipoteichoic acid-deficient Lactobacillus acidophilus
Q28247866The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype
Q33596629The CpG island methylator phenotype (CIMP) in colorectal cancer
Q38870781The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma.
Q39456907The Immune Biology of Microsatellite-Unstable Cancer
Q26745580The Immunogenicity of Colorectal Cancer in Relation to Tumor Development and Treatment
Q36261529The Influence of BRAF and KRAS Mutation Status on the Association between Aspirin Use and Survival after Colon Cancer Diagnosis
Q91678604The activating transcription factor 2: an influencer of cancer progression
Q37699177The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A.
Q38210477The effect of diet on the intestinal epigenome
Q58636039The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis
Q90341405The importance of stool DNA methylation in colorectal cancer diagnosis: A meta-analysis
Q37644797The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent
Q34139192The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner
Q55233897The molecular characteristics of colorectal cancer: Implications for diagnosis and therapy.
Q53326236The potential role of the NEK6, AURKA, AURKB, and PAK1 genes in adenomatous colorectal polyps and colorectal adenocarcinoma.
Q36476282The prognostic effect of PTEN expression status in colorectal cancer development and evaluation of factors affecting it: miR-21 and promoter methylation
Q50333457The prognostic efficacy of cell-free DNA hypermethylation in colorectal cancer
Q48266694The prognostic role of microsatellite instability, codon-specific KRAS, and BRAF mutations in colon cancer
Q38770200The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth
Q38215665The role of epigenetics in colorectal cancer
Q91689817Toll-like receptor 6 expression, sequence variants, and their association with colorectal cancer risk
Q49963185Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer.
Q64965261Transcutaneous Vagus Nerve Stimulation Regulates the Cholinergic Anti-inflammatory Pathway to Counteract 1, 2-Dimethylhydrazine Induced Colon Carcinogenesis in Albino wistar Rats.
Q50642659Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity.
Q37631429Tumor LINE-1 Methylation Level in Association with Survival of Patients with Stage II Colon Cancer.
Q34169734Tumor LINE-1 methylation level and microsatellite instability in relation to colorectal cancer prognosis
Q39194701Tumor suppressor genes in familial adenomatous polyposis
Q28069898Tumour biomarkers: homeostasis as a novel prognostic indicator
Q37708920Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis.
Q54979868Update on Sporadic Colorectal Cancer Genetics.
Q33859385Validation of methylation biomarkers that distinguish normal colon mucosa of cancer patients from normal colon mucosa of patients without cancer
Q58697697Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor in colon cancer cells
Q26766256Vitamin D and Colorectal, Breast, and Prostate Cancers: A Review of the Epidemiological Evidence
Q41111994WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy
Q37651410Zebrafish Discoveries in Cancer Epigenetics.

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