scholarly article | Q13442814 |
P2093 | author name string | Kanwal Tariq | |
Kulsoom Ghias | |||
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Specific alterations of microRNA transcriptome and global network structure in colorectal carcinoma after cetuximab treatment | Q28294448 | ||
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Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer | Q28305293 | ||
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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer | Q29614277 | ||
Evolution and functions of long noncoding RNAs | Q29614331 | ||
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma | Q29615026 | ||
Hypomethylation distinguishes genes of some human cancers from their normal counterparts | Q29619217 | ||
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas | Q29620630 | ||
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons | Q30524222 | ||
Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells | Q30637438 | ||
The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer. | Q31049554 | ||
Reconstitution of 5'-directed human mismatch repair in a purified system | Q33222844 | ||
Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach | Q33270665 | ||
Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus | Q33571385 | ||
Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer | Q33586020 | ||
SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway | Q33933528 | ||
Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors | Q33942280 | ||
Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer. | Q33956668 | ||
Clinical relevance of microsatellite instability in colorectal cancer | Q33990921 | ||
miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase | Q34013539 | ||
PTEN-deficient tumors depend on AKT2 for maintenance and survival | Q34016861 | ||
The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas | Q34020549 | ||
Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer. | Q34035601 | ||
Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex | Q34051999 | ||
High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease | Q36051517 | ||
Epigenetics and colorectal cancer | Q36081553 | ||
Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer | Q36086848 | ||
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. | Q36276940 | ||
The hallmarks of cancer: a long non-coding RNA point of view. | Q36391951 | ||
Polo-like kinase 1 is overexpressed in colorectal cancer and participates in the migration and invasion of colorectal cancer cells. | Q36577379 | ||
Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy | Q36610301 | ||
Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression. | Q36629423 | ||
A common genetic risk factor for colorectal and prostate cancer | Q36667989 | ||
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon | Q36697241 | ||
Long non-coding RNA in cancer | Q36790436 | ||
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer. | Q36852678 | ||
MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers | Q36906199 | ||
Identification of novel variants in colorectal cancer families by high-throughput exome sequencing | Q36991821 | ||
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening | Q37066133 | ||
Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: classification, molecular genetics, natural history, and clinical management | Q37099611 | ||
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer | Q37138668 | ||
MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial | Q37185814 | ||
Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis. | Q37209240 | ||
MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis | Q37209436 | ||
Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/β-catenin signal pathway. | Q37297589 | ||
The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment | Q37366259 | ||
Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators. | Q37570042 | ||
Genetic and epigenetic biomarkers for diagnosis, prognosis and treatment of colorectal cancer | Q37578728 | ||
The expanding universe of p53 targets | Q37602507 | ||
Spliced MDM2 isoforms promote mutant p53 accumulation and gain-of-function in tumorigenesis | Q37650965 | ||
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis | Q37679965 | ||
Inversion of exons 1-7 of the MSH2 gene is a frequent cause of unexplained Lynch syndrome in one local population | Q37699062 | ||
MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer | Q37715770 | ||
EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients | Q38069531 | ||
PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types | Q38084846 | ||
Role of microRNAs in the immune system, inflammation and cancer | Q38110271 | ||
Small molecule with big role: MicroRNAs in cancer metastatic microenvironments | Q38159262 | ||
Mismatch repair pathway: molecules, functions, and role in colorectal carcinogenesis. | Q38194897 | ||
The dual nature of mismatch repair as antimutator and mutator: for better or for worse | Q38246275 | ||
MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer. | Q38247982 | ||
ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer | Q38532510 | ||
Mutant p53 reprograms TNF signaling in cancer cells through interaction with the tumor suppressor DAB2IP. | Q38934179 | ||
Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g. | Q39112884 | ||
Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression | Q39249155 | ||
Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells. | Q39387335 | ||
Colon cancer associated transcript-1: a novel RNA expressed in malignant and pre-malignant human tissues. | Q39547104 | ||
MALAT-1: A long non-coding RNA and its important 3' end functional motif in colorectal cancer metastasis | Q39556569 | ||
Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells | Q39633529 | ||
Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells | Q39634084 | ||
miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation. | Q39677748 | ||
Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. | Q34069798 | ||
Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer | Q34116561 | ||
miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions | Q34237504 | ||
A CpG island methylator phenotype of colorectal cancer that is contiguous with conventional adenomas, but not serrated polyps | Q34293192 | ||
Centromere protein H is up-regulated in primary human colorectal cancer and its overexpression induces aneuploidy | Q34423165 | ||
The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer | Q34441849 | ||
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer | Q34461429 | ||
Mechanisms underlying losses of heterozygosity in human colorectal cancers | Q34485665 | ||
Prognostic value of CpG island methylator phenotype among colorectal cancer patients: a systematic review and meta-analysis. | Q34553646 | ||
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer | Q34563305 | ||
The chromosomal instability pathway in colon cancer | Q34570062 | ||
Microsatellite instability in colorectal cancer-the stable evidence | Q34616565 | ||
KRAS mutation testing in metastatic colorectal cancer | Q34643960 | ||
MALAT1 promotes colorectal cancer cell proliferation/migration/invasion via PRKA kinase anchor protein 9. | Q34718248 | ||
Association between molecular subtypes of colorectal cancer and patient survival | Q34759064 | ||
TP53 and let-7a micro-RNA regulate K-Ras activity in HCT116 colorectal cancer cells | Q34926012 | ||
American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy | Q34935716 | ||
Colon and endometrial cancers with mismatch repair deficiency can arise from somatic, rather than germline, mutations | Q34959257 | ||
Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas | Q35004950 | ||
MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells. | Q35008686 | ||
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. | Q35013762 | ||
Over-expression of COX-2 mRNA in colorectal cancer | Q35079511 | ||
Genetic variability in key genes in prostaglandin E2 pathway (COX-2, HPGD, ABCC4 and SLCO2A1) and their involvement in colorectal cancer development | Q35138248 | ||
P53 mutations occur more commonly than KRAS mutations in colorectal adenoma | Q35173907 | ||
Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer. | Q35293923 | ||
Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists | Q35459134 | ||
Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages | Q35579056 | ||
The 5-methylcytosine content of DNA from human tumors | Q35689206 | ||
The relationship between hypomethylation and CpG island methylation in colorectal neoplasia | Q35749254 | ||
Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer | Q35762264 | ||
Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers | Q35810106 | ||
Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample | Q35855515 | ||
Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database | Q35940640 | ||
Epigenetic regulation of microRNA expression in colorectal cancer | Q39838959 | ||
The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras | Q39860132 | ||
Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer | Q40847447 | ||
BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer | Q41056167 | ||
Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas | Q41603218 | ||
5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result | Q41668069 | ||
miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer | Q42051478 | ||
Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer | Q42175718 | ||
Telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer | Q43005462 | ||
Extensive telomere erosion in the initiation of colorectal adenomas and its association with chromosomal instability | Q43522906 | ||
Recurrence and variability of germline EPCAM deletions in Lynch syndrome. | Q44080353 | ||
Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro | Q44206354 | ||
Somatic mutations in MLH1 and MSH2 are a frequent cause of mismatch-repair deficiency in Lynch syndrome-like tumors | Q44383505 | ||
A novel classification of colorectal tumors based on microsatellite instability, the CpG island methylator phenotype and chromosomal instability: implications for prognosis. | Q44490075 | ||
Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability | Q44714286 | ||
Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene | Q45345254 | ||
Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer | Q45740901 | ||
MicroRNA signature in metastatic colorectal cancer patients treated with anti-EGFR monoclonal antibodies | Q45790076 | ||
Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis in patients with colorectal cancer. | Q46275729 | ||
Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer | Q46578998 | ||
Smad4 inactivation predicts for worse prognosis and response to fluorouracil-based treatment in colorectal cancer | Q46676671 | ||
Three classes of genes mutated in colorectal cancers with chromosomal instability | Q47652214 | ||
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability | Q47704165 | ||
Germline epimutation of MLH1 in individuals with multiple cancers | Q47817335 | ||
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer | Q48084125 | ||
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers | Q51856604 | ||
Role of miR-143 targeting KRAS in colorectal tumorigenesis | Q52591361 | ||
Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome | Q53085005 | ||
Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors | Q53258270 | ||
Loss of imprinting of IGF2 correlates with hypomethylation of the H19 differentially methylated region in the tumor tissue of colorectal cancer patients | Q53272678 | ||
Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications | Q54389429 | ||
Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. | Q54632294 | ||
CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels. | Q54797906 | ||
Variable 5-methylcytosine levels in human tumor cell lines and fresh pediatric tumor explants. | Q55489110 | ||
Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue | Q56589628 | ||
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer | Q57240062 | ||
Large genomic rearrangements and germline epimutations in Lynch syndrome | Q57671334 | ||
Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro | Q62061836 | ||
Hypomethylation of DNA from benign and malignant human colon neoplasms | Q69381419 | ||
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers | Q71167724 | ||
Allelic loss of chromosome 18q and prognosis in colorectal cancer | Q72024722 | ||
Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome | Q72657543 | ||
Hereditary colorectal cancer | Q73088287 | ||
Infrequent somatic mutation of the adenomatous polyposis coli gene in aberrant crypt foci of human colon tissue | Q77221792 | ||
Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability | Q77534962 | ||
Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2 | Q78532732 | ||
A new variant database for mismatch repair genes associated with Lynch syndrome | Q79909235 | ||
Oncogenic mutations of PIK3CA in human cancers | Q80826963 | ||
Genetic and epigenetic factors in regulation of microRNA in colorectal cancers | Q84990760 | ||
MicroRNAs in cancer | Q86065522 | ||
β-Catenin signaling dosage dictates tissue-specific tumor predisposition in Apc-driven cancer | Q87418047 | ||
P433 | issue | 1 | |
P921 | main subject | colorectal cancer | Q188874 |
carcinogenesis | Q1637543 | ||
colorectal carcinoma | Q25493920 | ||
P304 | page(s) | 120-135 | |
P577 | publication date | 2016-03-01 | |
P1433 | published in | Cancer Biology & Medicine | Q26841841 |
P1476 | title | Colorectal cancer carcinogenesis: a review of mechanisms | |
P478 | volume | 13 |
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