| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NG0894-536 |
| P698 | PubMed publication ID | 7951326 |
| P50 | author | Jean-Pierre J Issa | Q55459879 |
| P2093 | author name string | Hamilton SR | |
| Baylin SB | |||
| Davidson NE | |||
| Celano P | |||
| Ottaviano YL | |||
| P2860 | cites work | Evidence for estrogen receptor-linked calcium transport in the intestine | Q72813403 |
| Senescent decline in serum dehydroepiandrosterone sulfate concentrations in a population of wild baboons | Q72913383 | ||
| Sequence and expression of human estrogen receptor complementary DNA | Q24299678 | ||
| CpG-rich islands and the function of DNA methylation | Q28131800 | ||
| Analysis of upstream sequences of the human estrogen receptor gene | Q28304528 | ||
| Role for DNA methylation in genomic imprinting | Q29618669 | ||
| Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A | Q29619449 | ||
| The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia | Q33636876 | ||
| De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines | Q33738027 | ||
| Parental-origin-specific epigenetic modification of the mouse H19 gene | Q34363043 | ||
| Activated estrogen receptor mediates growth arrest and differentiation of a neuroblastoma cell line | Q36261902 | ||
| Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29 | Q36597146 | ||
| Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer | Q36869755 | ||
| Oestrogen receptors in colorectal carcinoma | Q37255525 | ||
| Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells | Q37327536 | ||
| Methylation analysis of CGG sites in the CpG island of the human FMR1 gene | Q38324995 | ||
| High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. | Q38339731 | ||
| The inheritance of epigenetic defects | Q39671673 | ||
| Gastrointestinal proliferation and aging | Q40896794 | ||
| Autoinduction of nuclear receptor genes and its significance | Q41005123 | ||
| The presence of functional estrogen receptors in intestinal epithelial cells | Q41094561 | ||
| Stable expression of the human estrogen receptor in HeLa cells by infection: effect of estrogen on cell proliferation and c-myc expression | Q41682653 | ||
| Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor | Q43655072 | ||
| Stable transfection of the oestrogen receptor gene into a human osteosarcoma cell line | Q43721094 | ||
| Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome | Q44959699 | ||
| Reproductive factors, exogenous female hormones, and colorectal cancer by subsite | Q46076992 | ||
| Methylation of CpG-island-containing genes in human sperm, fetal and adult tissues | Q46457249 | ||
| Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method | Q48086267 | ||
| Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. | Q48125063 | ||
| Ovulation-associated increase in intestinal calcium absorption during the rat estrous cycle is blunted by ovariectomy. | Q53801503 | ||
| Insights into X chromosome inactivation from studies of species variation, DNA methylation and replication, and vice versa | Q68650357 | ||
| A prospective study of reproductive history and exogenous estrogens on the risk of colorectal cancer in women | Q70197207 | ||
| Tissue-specific regulation of shell gland calbindin D28K biosynthesis by estradiol in precociously matured, vitamin D-depleted chicks | Q70526919 | ||
| Epigenetic mechanisms underlying the imprinting of the mouse H19 gene | Q72094721 | ||
| P433 | issue | 4 | |
| P921 | main subject | estrogen | Q277954 |
| CpG island | Q1138360 | ||
| P304 | page(s) | 536-540 | |
| P577 | publication date | 1994-08-01 | |
| P1433 | published in | Nature Genetics | Q976454 |
| P1476 | title | Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon | |
| P478 | volume | 7 |
| Q55480673 | 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers |
| Q38605223 | A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients with Ulcerative Colitis-associated Colorectal Cancer. |
| Q41523569 | A Prospective Evaluation of Endogenous Sex Hormone Levels and Colorectal Cancer Risk in Postmenopausal Women. |
| Q31063094 | A comprehensive catalog of CpG islands methylated in human lung adenocarcinomas for the identification of tumor suppressor genes |
| Q35986045 | A lack of ovarian function increases neuroinflammation in aged mice |
| Q37379744 | A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction. |
| Q40988629 | A possible role in chemical carcinogenesis for epigenetic, heritable changes in gene expression |
| Q37525099 | A prospective study of oral contraceptive use and colorectal adenomas |
| Q35792108 | Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic Inflammation |
| Q49668158 | Aberrant DNA Methylation in Colorectal Cancer: What Should We Target? |
| Q33185818 | Aberrant DNA methylation in pediatric patients with acute lymphocytic leukemia |
| Q30494652 | Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model |
| Q41317440 | Aberrant DNA methylation of ESR1 and p14ARF genes could be useful as prognostic indicators in osteosarcoma |
| Q36618056 | Aberrant DNA methylation of the p16INK4a gene in plasma DNA of breast cancer patients |
| Q33831996 | Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. |
| Q36573030 | Aberrant silencing of the CpG island-containing human O6-methylguanine DNA methyltransferase gene is associated with the loss of nucleosome-like positioning |
| Q36106406 | Abnormal DNA methylation in oocytes could be associated with a decrease in reproductive potential in old mice |
| Q41374924 | Accessibility to tissue-specific genes from methylation profiles of mouse brain genomic DNA. |
| Q37578731 | Accumulation of aberrant DNA methylation during colorectal cancer development |
| Q64058156 | Accumulation of genetic and epigenetic alterations in normal cells and cancer risk |
| Q36101113 | Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia |
| Q34272080 | Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. |
| Q57216138 | Age at menarche and risk of colorectal adenoma |
| Q34770060 | Age at menarche and risk of colorectal cancer: a meta-analysis |
| Q38328063 | Age-associated DNA methylation in pediatric populations |
| Q37195037 | Age-associated epigenetic drift: implications, and a case of epigenetic thrift? |
| Q33771976 | Age-associated epigenetic modifications in human DNA increase its immunogenicity |
| Q36404140 | Age-by-disease biological interactions: implications for late-life depression. |
| Q33762434 | Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. |
| Q73225268 | Age-dependent alterations in mRNA level and promoter methylation of collagen alpha1(I) gene in human periodontal ligament |
| Q46621464 | Age-dependent decrease in 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) activity in hypertensive patients |
| Q37655854 | Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation. |
| Q35571297 | Age-related epigenetic changes and the immune system |
| Q58696182 | Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites |
| Q37634230 | Ageing and cancer as diseases of epigenesis |
| Q35552256 | Aging and DNA methylation |
| Q37283233 | Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context |
| Q37410585 | Aging and epigenetic drift: a vicious cycle |
| Q35897286 | Aging and epigenetics: longitudinal changes in gene-specific DNA methylation |
| Q36766079 | Aging by epigenetics--a consequence of chromatin damage? |
| Q33787464 | Aging, DNA methylation and cancer |
| Q25255846 | Allellic variants in regulatory regions of cyclooxygenase-2: association with advanced colorectal adenoma |
| Q55479603 | Alteration of c-fos gene methylation in human gliomas. |
| Q56418625 | Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia |
| Q33775111 | An alternative promoter in the mouse major histocompatibility complex class II I-Abeta gene: implications for the origin of CpG islands |
| Q33519528 | An epigenetic signature in peripheral blood predicts active ovarian cancer |
| Q36485572 | Applying whole-genome studies of epigenetic regulation to study human disease |
| Q37376477 | Assessment of epigenetic alterations in early colorectal lesions containing BRAF mutations. |
| Q34681062 | Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa |
| Q83204767 | Association between polymorphisms in the XRCC1 and GST genes, and CpG island methylation status in colonic mucosa in ulcerative colitis |
| Q61445790 | Association between serum 25-hydroxyvitamin D and global DNA methylation in visceral adipose tissue from colorectal cancer patients |
| Q77374977 | Association of K-ras mutations with p16 methylation in human colon cancer |
| Q88334434 | BPA exposure is associated with non-monotonic alteration in ESR1 promoter methylation in peripheral blood of men and shorter relative telomere length in peripheral blood of women |
| Q85113142 | BRCA1 promoter methylation in peripheral blood cells is associated with increased risk of breast cancer with BRCA1 promoter methylation |
| Q41274606 | BRCA2 carriers with male breast cancer show elevated tumour methylation |
| Q28073173 | Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan |
| Q35916793 | Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies |
| Q36213486 | Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. |
| Q34558159 | Biology and genetics of colorectal cancer |
| Q34630070 | COBRA: a sensitive and quantitative DNA methylation assay |
| Q28207134 | CYP1B1 gene in endometrial cancer |
| Q40638054 | Caloric restriction delays age-related methylation drift |
| Q29617275 | Cancer epigenetics comes of age |
| Q34253580 | Cancer genetics. |
| Q35034857 | Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice |
| Q33602258 | Carcinogenesis and natural selection: a new perspective to the genetics and epigenetics of colorectal cancer |
| Q38221517 | Causes and Consequences of Age-Related Changes in DNA Methylation: A Role for ROS? |
| Q34353359 | Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma |
| Q33902908 | Chemoprevention for colorectal cancer. |
| Q33588661 | Chromatin modifications: the driving force of senescence and aging? |
| Q34080232 | Chromatin remodeling in mammary gland differentiation and breast tumorigenesis |
| Q37810688 | Chromatin: a molecular interface between cancer and aging |
| Q73793311 | Chromosome assignment of aberrant NotI restriction DNA fragments in primary hepatocellular carcinoma |
| Q45285358 | Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa |
| Q36126670 | Clinical characteristics of hepatocellular carcinoma in elderly patients |
| Q40828841 | Clinical models of chemoprevention for colon cancer |
| Q40692246 | Cloning of the 5' upstream region of the rat p16 gene and its role in silencing |
| Q33284068 | Colon cancer risk and different HRT formulations: a case-control study |
| Q47221741 | Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro |
| Q38321887 | Colorectal cancer screening and prevention in women |
| Q26751646 | Colorectal cancers and chlorinated water |
| Q26864051 | Common features of chromatin in aging and cancer: cause or coincidence? |
| Q30537190 | Common single-nucleotide polymorphisms in the estrogen receptor β promoter are associated with colorectal cancer survival in postmenopausal women |
| Q58764428 | Comprehensive analysis identifying aberrant DNA methylation in rectal mucosa from ulcerative colitis patients with neoplasia |
| Q37081063 | Concepts of epigenetics in prostate cancer development |
| Q38239816 | Concise review: dedifferentiation meets cancer development: proof of concept for epigenetic cancer |
| Q35747320 | Concordant CpG island methylation in hyperplastic polyposis. |
| Q54771817 | Concurrent hypermethylation of gene promoters is associated with a MSI-H phenotype and diploidy in gastric carcinomas. |
| Q39728639 | Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts |
| Q33617224 | Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions? |
| Q36343388 | CpG island hypermethylation in gastric carcinoma and its premalignant lesions |
| Q35746792 | CpG island methylation in colorectal adenomas |
| Q81080870 | CpG island methylator phenotype in cancer |
| Q24672170 | CpG island methylator phenotype in colorectal cancer |
| Q26851776 | CpG island methylator phenotype, Helicobacter pylori, Epstein-Barr virus, and microsatellite instability and prognosis in gastric cancer: a systematic review and meta-analysis |
| Q37081080 | CpG-island methylation of the ER promoter in colorectal cancer: analysis of micrometastases in lymph nodes from UICC stage I and II patients |
| Q31875103 | Crucial role of cytokines in sex steroid formation in normal and tumoral tissues |
| Q55004192 | Cysteine dioxygenase type 1 (CDO1) gene promoter methylation during the adenoma-carcinoma sequence in colorectal cancer. |
| Q37883042 | Cytosine methyltransferases as tumor markers |
| Q60303919 | DNA Methylation Clocks in Aging: Categories, Causes, and Consequences |
| Q36301656 | DNA Methylation Dynamics During Differentiation, Proliferation, and Tumorigenesis in the Intestinal Tract |
| Q50040373 | DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk |
| Q36117983 | DNA Methylation Predicts Progression of Human Gastric Lesions |
| Q36069167 | DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors |
| Q34696425 | DNA alterations in body fluids as molecular tumor markers for urological malignancies |
| Q36613849 | DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer |
| Q33870798 | DNA hypermethylation in tumorigenesis: epigenetics joins genetics |
| Q34566703 | DNA hypermethylation markers of poor outcome in laryngeal cancer |
| Q37021152 | DNA hypermethylation profiles in squamous cell carcinoma of the vulva |
| Q34603514 | DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer. |
| Q36519113 | DNA methylation as a marker for the past and future |
| Q41730013 | DNA methylation as a target for drug design |
| Q35062112 | DNA methylation changes in gastrointestinal disease. |
| Q35019579 | DNA methylation in cancer and ageing |
| Q37280956 | DNA methylation in circulating tumour DNA as a biomarker for cancer |
| Q27023922 | DNA methylation in gastric cancer, related to Helicobacter pylori and Epstein-Barr virus |
| Q33634174 | DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids. |
| Q35240788 | DNA methylation of SPARC and chronic low back pain |
| Q34544990 | DNA methylation of nuclear receptor genes--possible role in malignancy |
| Q35051119 | DNA methylation predicts recurrence from resected stage III proximal colon cancer |
| Q33957042 | DNA methylation profile of the mouse skeletal alpha-actin promoter during development and differentiation |
| Q33533746 | DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines |
| Q34087965 | DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis |
| Q34323103 | DNA methylation status of epithelial-mesenchymal transition (EMT)--related genes is associated with severe clinical phenotypes in ulcerative colitis (UC). |
| Q33517453 | DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. |
| Q38229830 | DNA methylation, ageing and the influence of early life nutrition |
| Q37440102 | DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging |
| Q30993657 | DNA methylation, methyltransferases, and cancer |
| Q47152953 | DNA methylation-based age prediction from various tissues and body fluids. |
| Q37232224 | DNA methylation: a marker for carcinogen exposure and cancer risk |
| Q34290123 | DNA methylation: an alternative pathway to cancer |
| Q41723122 | DNA methylator and mismatch repair phenotypes are not mutually exclusive in colorectal cancer cell lines |
| Q36546471 | DNA methylome signature in rheumatoid arthritis |
| Q37269445 | DNA promoter hypermethylation in nipple fluid: a potential tool for early breast cancer detection |
| Q37064970 | DNA/RNA markers for colorectal cancer risk in preserved stool specimens: a pilot study |
| Q36561731 | De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase |
| Q34103976 | Decreased expression of 17β-hydroxysteroid dehydrogenase type 1 is associated with DNA hypermethylation in colorectal cancer located in the proximal colon. |
| Q48075151 | Demethylation of a repetitive DNA sequence in human cancers |
| Q74690591 | Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers |
| Q81416192 | Detection and interpretation of altered methylation patterns in cancer cells |
| Q53273653 | Detection of DNA hypermethylation in remote media of patients with colorectal cancer: new biomarkers for colorectal carcinoma. |
| Q35093755 | Detection of bladder cancer using novel DNA methylation biomarkers in urine sediments |
| Q36184207 | Diet and aging |
| Q36628688 | Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer |
| Q35748341 | Dietary phytoestrogen intake is associated with reduced colorectal cancer risk |
| Q28239338 | Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer |
| Q37329192 | Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice |
| Q36041771 | Dissecting DNA hypermethylation in cancer. |
| Q91910602 | Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori |
| Q34975498 | Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype |
| Q37143466 | Distinctive topology of age-associated epigenetic drift in the human interactome |
| Q54770071 | Downregulation of CD44v6 in colorectal carcinomas is associated with hypermethylation of the CD44 promoter region. |
| Q36762940 | Dynamic regulation of estrogen receptor-alpha gene expression in the brain: a role for promoter methylation? |
| Q40777790 | E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells |
| Q92515847 | E2F1 mediates the downregulation of POLD1 in replicative senescence |
| Q37552436 | EGFR(s) in aging and carcinogenesis of the gastrointestinal tract. |
| Q41821446 | Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats |
| Q35597336 | Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma |
| Q37179872 | Effects of Sirt1 on DNA methylation and expression of genes affected by dietary restriction |
| Q35013798 | Emerging patterns of epigenomic variation |
| Q43011246 | Endothelin B receptor gene hypermethylation in prostate adenocarcinoma |
| Q44425110 | Enrichment for Histone H3 Lysine 9 Methylation at Alu Repeats in Human Cells |
| Q34487177 | Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers |
| Q36942972 | Epigenetic Aspects of Systemic Lupus Erythematosus |
| Q93164511 | Epigenetic Clock: Just a Convenient Marker or an Active Driver of Aging? |
| Q35697918 | Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants |
| Q33998774 | Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targets |
| Q38837858 | Epigenetic Determinants of Cancer |
| Q33914854 | Epigenetic Interactions between Alcohol and Cannabinergic Effects: Focus on Histone Modification and DNA Methylation |
| Q61759611 | Epigenetic Significance of Chromatin Organization During Cellular Aging and Organismal Lifespan |
| Q24625376 | Epigenetic alterations in aging |
| Q34460981 | Epigenetic control of aging |
| Q53335869 | Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention. |
| Q80731971 | Epigenetic events underlie the pathogenesis of sinonasal papillomas |
| Q35058996 | Epigenetic gene silencing in cancer initiation and progression |
| Q36791094 | Epigenetic markers for bladder cancer in urine |
| Q83829640 | Epigenetic mechanisms in Alzheimer's disease |
| Q37332214 | Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells |
| Q21245250 | Epigenetic regulation of caloric restriction in aging |
| Q36736072 | Epigenetic regulation of colon cancer and intestinal stem cells |
| Q38244664 | Epigenetic regulation of female puberty. |
| Q22122053 | Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals |
| Q35985447 | Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. |
| Q34541756 | Epigenetic susceptibility factors for prostate cancer with aging. |
| Q84597148 | Epigenetic variation and cellular Darwinism |
| Q55113211 | Epigenetics and Human Disease. |
| Q36081553 | Epigenetics and colorectal cancer |
| Q71031916 | Epigenetics and human disease |
| Q37355967 | Epigenetics of acute lymphocytic leukemia |
| Q24598045 | Epigenetics of colorectal cancer |
| Q33888465 | Epigenetics: Linking Nutrition to Molecular Mechanisms in Aging |
| Q35711475 | Epigenomics in environmental health |
| Q22255392 | Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review) |
| Q31875169 | Estrogen metabolism and malignancy: analysis of the expression and function of 17beta-hydroxysteroid dehydrogenases in colonic cancer |
| Q44090462 | Estrogen metabolism in human colorectal cancer cells |
| Q54204521 | Estrogen receptor promoter methylation predicts survival in low-grade ovarian carcinoma patients. |
| Q37412030 | Estrogen receptor α or β loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFβ and HNF3β signaling |
| Q34468772 | Estrogen receptor-alpha gene expression in the cortex: sex differences during development and in adulthood |
| Q21284766 | Estrogen signaling and the aging brain: context-dependent considerations for postmenopausal hormone therapy |
| Q28678232 | Evolution of the cancer genome |
| Q35111866 | Examination of whole blood DNA methylation as a potential risk marker for gastric cancer |
| Q35966800 | Expression genetics in cancer: shifting the focus from DNA to RNA. |
| Q41714958 | Expression genetics: a different approach to cancer diagnosis and prognosis |
| Q53284573 | Expression of NHERF1 in colonic tumors induced by 1,2-dimethylhydrazine in rats is independent of plasma ovarian steroids. |
| Q50886042 | Expression of oestrogen receptor and oestrogen-inducible genes pS2 and ERD5 in large bowel mucosa and cancer. |
| Q37261068 | Fetal exposure to cocaine causes programming of Prkce gene repression in the left ventricle of adult rat offspring |
| Q73102812 | Frequency of loss of hMLH1 expression in colorectal carcinoma increases with advancing age |
| Q74460330 | Functional analysis of CpG methylation in the BRCA1 promoter region |
| Q47970740 | Gender-related prognostic significance of clinical and biological tumor features in rectal cancer patients receiving short-course preoperative radiotherapy. |
| Q37214302 | Genetic epidemiology in aging research |
| Q33862850 | Genetic variation in sex-steroid receptors and synthesizing enzymes and colorectal cancer risk in women |
| Q57977995 | Genetics supersedes epigenetics in colon cancer phenotype |
| Q35163122 | Genome instability, cancer and aging |
| Q35112893 | Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis. |
| Q30491042 | Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma |
| Q36149209 | Global heterochromatin loss: a unifying theory of aging? |
| Q74184034 | HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomas |
| Q47714141 | Helicobacter pylori infection increases the risk of colorectal adenoma and adenocarcinoma, especially in women |
| Q35283649 | High incidence of LRAT promoter hypermethylation in colorectal cancer correlates with tumor stage |
| Q38450827 | High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas. |
| Q46324010 | Higher parity and earlier age at first birth are associated with lower risk of death from colon cancer |
| Q34451733 | Histone methylation and acetylation indicates epigenetic change in the aged cochlea of mice |
| Q36236071 | Hormonal influences on cancer progression and prognosis |
| Q47963206 | Hormone replacement therapy and cancer risk: A systematic analysis from a network of case‐control studies |
| Q35134612 | Hormone replacement therapy and endometrial, ovarian and colorectal cancer. |
| Q33884570 | Hormone therapy, DNA methylation and colon cancer |
| Q35882825 | How The Genome Got a Life Span. |
| Q33821591 | Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation |
| Q36192462 | Human tissue kallikreins: from gene structure to function and clinical applications |
| Q73787556 | Hypermethylation at 9q32-33 tumour suppressor region is age-related in normal urothelium and an early and frequent alteration in bladder cancer |
| Q44456211 | Hypermethylation can selectively silence multiple promoters of steroid receptors in cancers |
| Q77620687 | Hypermethylation of the CDKN2/p16 promoter during neoplastic progression in Barrett's esophagus |
| Q41931639 | Hypermethylation of the WT1 and calcitonin gene promoter regions at chromosome 11p in human colorectal cancer |
| Q79347804 | Hypermethylation of the hMLH1 promoter with absent hMLH1 expression in medullary-type poorly differentiated colorectal adenocarcinoma in the elderly |
| Q40981873 | Hypomethylation of an exon I estrogen receptor CpG island in spontaneous and carcinogen-induced mammary tumorigenesis in the rat. |
| Q36121608 | Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis. |
| Q36571511 | Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling |
| Q35119503 | Impact of aging on DNA methylation |
| Q57021380 | Implications of epigenetic drift in colorectal neoplasia |
| Q37628234 | Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer |
| Q73109347 | Increased upstream methylation has no influence on the overexpression of the parathyroid hormone-related protein gene in squamous cell carcinoma of the lung |
| Q34528757 | Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1 in the gastric epithelium |
| Q34349990 | Influence of IL17A polymorphisms on the aberrant methylation of DAPK and CDH1 in non-cancerous gastric mucosa |
| Q36616379 | Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer. |
| Q41439646 | Influence of oxygen radical injury on DNA methylation. |
| Q36705872 | Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells |
| Q34478629 | Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women |
| Q44141789 | Intake of dietary folate vitamers and risk of colorectal carcinoma: results from The Netherlands Cohort Study |
| Q36276940 | Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. |
| Q24291681 | Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2 |
| Q30654912 | Isolation of DNA fragments associated with methylated CpG islands in human adenocarcinomas of the lung using a methylated DNA binding column and denaturing gradient gel electrophoresis |
| Q52641460 | Key genes and regulatory networks involved in the initiation, progression and invasion of colorectal cancer. |
| Q34445924 | Keynote: mechanisms of senescence--complificationists versus simplificationists |
| Q33283510 | LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability |
| Q42241147 | Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer |
| Q59344212 | Loss of E-cadherin expression resulting from promoter hypermethylation in oral tongue carcinoma and its prognostic significance |
| Q55473882 | Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastoma. |
| Q34620502 | Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer |
| Q37520354 | Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells |
| Q46198160 | MTHFR 677T carrier influences the methylation status of H. pylori-infected gastric mucosa in older subjects |
| Q34271721 | MYOD-1 in normal colonic mucosa--role as a putative biomarker? |
| Q36854306 | Mechanisms of disease: the developmental origins of disease and the role of the epigenotype. |
| Q37102553 | Menopausal hormone therapy and risk of colorectal cancer |
| Q41664444 | Menopause and post-menopause |
| Q34341910 | Menopause, hormone replacement therapy and cancer |
| Q92286873 | Methionine Synthase Reductase-A66G and -C524T Single Nucleotide Polymorphisms and Prostate Cancer: A Case-Control Trial |
| Q38262063 | Methionine adenosyltransferase α2 sumoylation positively regulate Bcl-2 expression in human colon and liver cancer cells |
| Q37620965 | Methods for genome-wide analysis of DNA methylation in intestinal tumors |
| Q24515378 | MethyLight: a high-throughput assay to measure DNA methylation |
| Q36891370 | Methylated DNA sequences for early cancer detection, molecular classification and chemotherapy response prediction |
| Q36879112 | Methylation Markers for Early Detection and Differentiation of Follicular Thyroid Cancer Subtypes |
| Q36209679 | Methylation and mutation analysis of p16 gene in gastric cancer |
| Q43796904 | Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression |
| Q28364163 | Methylation matters |
| Q36294864 | Methylation of CpG island is not a ubiquitous mechanism for the loss of oestrogen receptor in breast cancer cells |
| Q42632071 | Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene |
| Q35607381 | Methylation of multiple genes in gastric glands with intestinal metaplasia: A disorder with polyclonal origins |
| Q41203475 | Methylation of polycomb target genes in intestinal cancer is mediated by inflammation |
| Q42856300 | Methylation of the E-cadherin gene in bladder neoplasia and in normal urothelial epithelium from elderly individuals |
| Q81741369 | Methylation of the RASSF1A tumor suppressor gene promoter. Risk factor for carcinogenesis of urological tumors |
| Q39452723 | Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent |
| Q35597680 | Methylation of the oestrogen receptor gene in non-neoplastic epithelium as a marker of colorectal neoplasia risk in longstanding and extensive ulcerative colitis |
| Q35596441 | Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer |
| Q40193786 | Methylation profile in benign, borderline and malignant ovarian tumors. |
| Q53384886 | Methylation profile of the MLH1 promoter region and their relationship to colorectal carcinogenesis. |
| Q54569398 | Methylation status and protein expression of RASSF1A in breast cancer patients. |
| Q36643725 | Methylation status of oestrogen receptor-alpha gene promoter sequences in human ovarian epithelial cell lines |
| Q36397142 | Methylation status of p16 gene in colorectal carcinoma and normal colonic mucosa |
| Q54759183 | Methylation, aging, and pediatric acute lymphocytic leukemia. |
| Q24631957 | Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands |
| Q24673086 | Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis |
| Q61758656 | Methylational urinalysis: a prospective study of bladder cancer patients and age stratified benign controls |
| Q24645663 | MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer |
| Q33990340 | Mismatch repair polymorphisms and risk of colon cancer, tumour microsatellite instability and interactions with lifestyle factors |
| Q36237392 | Molecular Features and Methylation Status in Early Onset (≤40 Years) Colorectal Cancer: A Population Based, Case-Control Study. |
| Q34181207 | Molecular and cellular determinants of estrogen receptor alpha expression |
| Q40955399 | Molecular genetic changes in benign colorectal tumors synchronous with microsatellite unstable carcinomas do not support a field defect |
| Q33857623 | Molecular mechanisms of inactivation of TGF-beta receptors during carcinogenesis |
| Q57655214 | Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors |
| Q39312968 | Neuronal pentraxin II (NPTX2) is frequently down-regulated by promoter hypermethylation in pancreatic cancers |
| Q37514010 | New nucleophilic mechanisms of ros-dependent epigenetic modifications: comparison of aging and cancer |
| Q37397324 | No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women |
| Q28744606 | No effect of folic acid supplementation on global DNA methylation in men and women with moderately elevated homocysteine |
| Q51670556 | Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters. |
| Q36296760 | Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning. |
| Q48503260 | Novel epigenetic markers for gastric cancer risk stratification in individuals after Helicobacter pylori eradication |
| Q34307174 | Nuclear nano-morphology markers of histologically normal cells detect the "field effect" of breast cancer |
| Q41146585 | Nutrition and colorectal cancer |
| Q37952442 | Nutritional influences on epigenetics and age-related disease |
| Q38074097 | Oestrogen and colorectal cancer: mechanisms and controversies |
| Q43708429 | Oestrogen and vitamin D receptor (VDR) genotypes and the expression of ErbB-2 and EGF receptor in human rectal cancers |
| Q62805283 | Oestrogen receptors and microsatellite instability in colorectal carcinoma patients |
| Q53335948 | Oestrogen replacement therapy reduces total plasma homocysteine and enhances genomic DNA methylation in postmenopausal women. |
| Q37295450 | On the role of autophagy in human diseases: a gender perspective |
| Q35920783 | Oral contraceptive use and colorectal cancer in the Nurses' Health Study I and II |
| Q34417633 | Oral contraceptives and cancer: an update |
| Q47912543 | Oral contraceptives and colorectal cancer |
| Q36622718 | Oral contraceptives and colorectal cancer risk: a meta-analysis |
| Q33545893 | Oral contraceptives and colorectal tumors. A review of epidemiologic studies |
| Q34363520 | Oral contraceptives, reproductive history and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition |
| Q34338919 | P53 mutations in thyroid carcinoma: tidings from an old foe. |
| Q28242802 | PELP1 suppression inhibits colorectal cancer through c-Src downregulation |
| Q34061112 | Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors |
| Q36359174 | Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays |
| Q35132134 | Polymerase chain reaction-based methods of DNA methylation analysis |
| Q73934848 | Possible prediction of myeloid and lymphoid crises in chronic myelocytic leukemia at onset by determining the methylation status of the major breakpoint cluster region |
| Q33640006 | Postmenopausal hormone therapy and the risk of colorectal cancer: a review and meta-analysis |
| Q36144782 | Postnatal development- and age-related changes in DNA-methylation patterns in the human genome |
| Q33544278 | Potential protective mechanisms of wheat bran fiber |
| Q44642898 | Prediction of nodal spread of breast cancer by using artificial neural network-based analyses of S100A4, nm23 and steroid receptor expression |
| Q79175646 | Prevalence of aberrant methylation of p14ARF over p16INK4a in some human primary tumors |
| Q34165145 | Primary prevention of colorectal cancer |
| Q36755132 | Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa |
| Q35773294 | Profiling ribonucleotide modifications at full-transcriptome level: a step toward MS-based epitranscriptomics |
| Q36358803 | Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma |
| Q39391704 | Promoter methylation in head and neck tumorigenesis |
| Q39871972 | Promoter methylation of protease-activated receptor (PAR2) is associated with severe clinical phenotypes of ulcerative colitis (UC). |
| Q28216984 | Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia |
| Q42124211 | Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma |
| Q35792273 | Prospects for epigenetic epidemiology |
| Q33540332 | Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients |
| Q37225328 | Radiation-stimulated epigenetic reprogramming of adaptive-response genes in the lung: an evolutionary gift for mounting adaptive protection against lung cancer |
| Q28477414 | Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers |
| Q26778407 | Regulation of Estrogen Receptor α Expression in the Hypothalamus by Sex Steroids: Implication in the Regulation of Energy Homeostasis |
| Q34364484 | Regulation of the DNA methylation machinery and its role in cellular transformation |
| Q34335025 | Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas |
| Q34920036 | Reproductive hormones and cancer: ovarian and colon cancer |
| Q34416420 | Research on biomedical gerontology in Japan |
| Q34803182 | Restriction landmark genomic scanning for DNA methylation in cancer: past, present, and future applications |
| Q36800212 | Reversibility of aberrant global DNA and estrogen receptor-alpha gene methylation distinguishes colorectal precancer from cancer. |
| Q33751727 | Role of DNA methylation in the regulation of cell function |
| Q36991794 | Role of estrogen receptor alpha and beta expression and signaling on cognitive function during aging |
| Q34479909 | Role of estrogen receptor beta in colonic epithelium |
| Q80637295 | SFRP2 methylation in fecal DNA--a marker for colorectal polyps |
| Q34801751 | Senescence and epigenetic dysregulation in cancer |
| Q52188018 | Sequence-specific methylation of the mouse H19 gene in embryonic cells deficient in the Dnmt-1 gene. |
| Q49569216 | Significance of intratissue estrogen concentration coupled with estrogen receptors levels in colorectal cancer prognosis. |
| Q34053843 | Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas |
| Q92494610 | Slowing Down Ageing: The Role of Nutrients and Microbiota in Modulation of the Epigenome |
| Q36220166 | Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome. |
| Q33857897 | Smoking, gender, and ethnicity predict somatic BRAF mutations in colorectal cancer |
| Q34013668 | Somatic cell mutations: can they provide a link between aging and cancer? |
| Q36605667 | Somatic stem cells and the origin of cancer |
| Q38303409 | Soy and isoflavone consumption and risk of gastrointestinal cancer: a systematic review and meta-analysis |
| Q36015150 | Soy isoflavone consumption and colorectal cancer risk: a systematic review and meta-analysis |
| Q37941287 | Stochastic modulations of the pace and patterns of ageing: impacts on quasi-stochastic distributions of multiple geriatric pathologies |
| Q35140542 | Stress and the epigenetic landscape: a link to the pathobiology of human diseases? |
| Q37268177 | Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis |
| Q37446299 | TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors |
| Q34734381 | TLR2 promoter hypermethylation creates innate immune dysbiosis |
| Q45146069 | Tamoxifen-resistant breast cancers show less frequent methylation of the estrogen receptor beta but not the estrogen receptor alpha gene |
| Q42252961 | Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice. |
| Q38821103 | Targeting the cancer epigenome for therapy |
| Q34321272 | Temporal stability of epigenetic markers: sequence characteristics and predictors of short-term DNA methylation variations |
| Q33543982 | The DNA methylation paradox |
| Q36646576 | The Diagnostic and Prognostic Role of microRNA in Colorectal Cancer - a Comprehensive review |
| Q34088387 | The age of cancer |
| Q37318403 | The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia |
| Q89055816 | The causal relationship between epigenetic abnormality and cancer development: in vivo reprogramming and its future application |
| Q33627935 | The central role of chromatin maintenance in aging |
| Q29617486 | The epigenetic progenitor origin of human cancer |
| Q24646282 | The epigenetics of sex differences in the brain |
| Q56421597 | The fundamental role of epigenetic events in cancer |
| Q37172151 | The genomics of colorectal cancer: state of the art. |
| Q28391041 | The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood |
| Q40982326 | The influence of hormone therapies on colon and rectal cancer |
| Q39029674 | The integration of epigenetics and genetics in nutrition research for CVD risk factors. |
| Q59549779 | The interaction of age and hormone replacement therapy on colon adenoma risk |
| Q43463157 | The methylation status and protein expression of CDH1, p16(INK4A), and fragile histidine triad in nonsmall cell lung carcinoma: epigenetic silencing, clinical features, and prognostic significance |
| Q35937970 | The molecular landscape of premenopausal breast cancer |
| Q36833557 | The myelodysplastic syndrome as a prototypical epigenetic disease |
| Q37903980 | The potential role of epigenetic responses to diet in ageing |
| Q28188233 | The power and the promise of DNA methylation markers |
| Q54760217 | The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis. |
| Q33837999 | The role of DNA hypermethylation in human neoplasia |
| Q27025194 | The role of DNA methylation in aging, rejuvenation, and age-related disease |
| Q28389137 | The role of epigenetic mechanisms and processes in autoimmune disorders |
| Q40911298 | Transcriptional repression of the transforming growth factor-beta type I receptor gene by DNA methylation results in the development of TGF-beta resistance in human gastric cancer |
| Q56967770 | Translation of Cancer Molecular Biomarkers: Ethical and Epistemological Issues |
| Q24293580 | Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses |
| Q37708920 | Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis. |
| Q30428760 | Understanding and manipulating O6-methylguanine-DNA methyltransferase expression |
| Q57064889 | Variation in DNA Methylation of Human Blood over a 1-Year Period using the Illumina MethylationEPIC array |
| Q37341821 | Vascular endothelial estrogen receptor alpha is modulated by estrogen status and related to endothelial function and endothelial nitric oxide synthase in healthy women |
| Q33736551 | Widespread and tissue specific age-related DNA methylation changes in mice. |
| Q37640131 | Xenoestrogens challenge 17β-estradiol protective effects in colon cancer |
| Q24313244 | p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3 |
| Q34015848 | p66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis. |
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