Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma

scientific article published on January 2000

Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1052426657
P356DOI10.1054/BJOC.1999.0889
P8608Fatcat IDrelease_5zxwga5ua5ci7eqexr4lqf3dyu
P932PMC publication ID2363214
P698PubMed publication ID10638979
P5875ResearchGate publication ID12675460

P50authorAlexander DobrovicQ30506435
P2093author name stringCowled PA
Butler LM
Bianco T
P2860cites workA genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strandsQ24562877
Roles of histone acetyltransferases and deacetylases in gene regulationQ28286019
Suppression of human colorectal carcinoma cell growth by wild-type p53Q29618318
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell linesQ29620526
Deregulation of apoptosis in colorectal carcinoma: theoretical and therapeutic implicationsQ33536031
Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosisQ34307869
Allelotype of colorectal carcinomasQ34461209
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factorQ34661010
Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactionsQ36158038
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expressionQ36551292
Characterization of human Fas gene. Exon/intron organization and promoter regionQ36677227
Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitmentQ39444883
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.Q39777499
Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.Q41270546
Identification of a silencer, enhancer, and basal promoter region in the human CD95 (Fas/APO-1) geneQ41278841
Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.Q41525198
Alterations in DNA methylation: a fundamental aspect of neoplasiaQ41617101
Down-regulation of Fas gene expression in colon cancer is not a result of allelic loss or gene rearrangementQ41893919
Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epitheliumQ42808304
Abnormal methylation of the calcitonin gene in human colonic neoplasms.Q46002586
Structure of the human APO-1 geneQ48077815
Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma.Q54569063
Monoclonal antibody-mediated tumor regression by induction of apoptosis.Q55059937
Single-strand and double-strand cleavage at half-modified and fully modified recognition sites for the restriction nucleases Sau3a and TaqiQ64390733
Hypomethylation of DNA from benign and malignant human colon neoplasmsQ69381419
Upregulated expression of Fas antigen on cultured human keratinocytes with induction of apoptosis by cisplatinQ71341959
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colonQ72781919
Hypermethylation of the Myf-3 gene in human colorectal cancerQ73147617
The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivoQ73903403
Up-regulation of Fas (CD95) in human p53wild-type cancer cells treated with ionizing radiationQ73939980
Aging and DNA methylation in colorectal mucosa and cancerQ77670111
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)131-135
P577publication date2000-01-01
P1433published inBritish Journal of CancerQ326309
P1476titlePromoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma
P478volume82

Reverse relations

cites work (P2860)
Q34397739Alteration of DNA methylation in gastrointestinal carcinogenesis
Q59219447Alterations of Fas (APO-1/CD 95) gene and its relationship with p53 in non small cell lung cancer
Q35026049Changes in apoptosis during the development of colorectal cancer: a systematic review of the literature
Q38202821DNA methylation and apoptosis resistance in cancer cells
Q39079636Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer
Q42281992Epigenetic inactivation of tumour suppressor coding and non-coding genes in human cancer: an update
Q73897125Evidence of a possible epigenetic inactivation mechanism operating on a region of mouse chromosome 19 in gamma-radiation-induced thymic lymphomas
Q36695892Expression of FAP-1 by human colon adenocarcinoma: implication for resistance against Fas-mediated apoptosis in cancer
Q34087916Fas expression in metastatic osteosarcoma cells is not regulated by CpG island methylation
Q38472616Functional aspects of cytidine-guanosine dinucleotides and their locations in genes
Q38283094Gene expression profiles of bladder cancers: evidence for a striking effect of in vitro cell models on gene patterns
Q40344731Human chorionic gonadotropin beta (HCGbeta) down-regulates E-cadherin and promotes human prostate carcinoma cell migration and invasion
Q44407056Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma
Q44062524IFN-gammaupregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma
Q28344462Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis
Q64955692Mechanism of Apoptosis Induced by Curcumin in Colorectal Cancer.
Q34378429Methylation and colorectal cancer
Q38219841Participation of the Fas/FasL signaling pathway and the lung microenvironment in the development of osteosarcoma lung metastases.
Q37000981Promoter hypermethylation and downregulation of the FAS gene may be involved in colorectal carcinogenesis
Q35587994Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum?
Q44635878The analysis of immunophenotype of gastrin-producing tumors of the pancreas and gastrointestinal tract.

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