DNA repair and colorectal cancer

scientific article published on December 1996

DNA repair and colorectal cancer is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S0889-8553(05)70273-9
P698PubMed publication ID8960891

P2093author name stringMarra G
Boland CR
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Mutations of two PMS homologues in hereditary nonpolyposis colon cancerQ24318484
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instabilityQ24319995
A genetic model for colorectal tumorigenesisQ27860582
Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiaeQ27937244
The yeast gene MSH3 defines a new class of eukaryotic MutS homologues.Q27937756
Mutation of a mutL homolog in hereditary colon cancerQ28114939
Binding of mismatched microsatellite DNA sequences by the human MSH2 proteinQ28241673
Colon cancer and DNA repair: have mismatches met their match?Q28245366
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancerQ28257360
Genetic mapping of a locus predisposing to human colorectal cancerQ28268634
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor CellsQ28292781
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cellsQ28292790
Mutations of GTBP in genetically unstable cellsQ28292802
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancerQ28294774
Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutationsQ28299699
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repairQ29615027
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repairQ29618879
In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancerQ71737275
MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repairQ71919357
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instabilityQ72127255
Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patientsQ72608543
Microsatellite instability in cancer of the proximal colonQ29620692
Detection of new mutations in six out of 10 Swiss HNPCC families by genomic sequencing of the hMSH2 and hMLH1 genesQ33682850
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell linesQ33720790
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiaeQ33842093
Founding mutations and Alu-mediated recombination in hereditary colon cancerQ34297390
Allelotype of colorectal carcinomasQ34461209
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologsQ34554581
The molecular basis of Turcot's syndromeQ34662365
DNA mismatch correction in a defined systemQ34674714
Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumorsQ35282280
Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB.Q36182527
Self-destruction and tolerance in resistance of mammalian cells to alkylation damageQ36277253
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.Q36412005
Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiaeQ36557503
Misalignment-mediated DNA synthesis errorsQ36613826
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reactionQ37265131
One role for DNA methylation in vertebrate cells is strand discrimination in mismatch repairQ37553690
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosisQ38293261
Genetic instability occurs in the majority of young patients with colorectal cancerQ38297232
The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertionsQ38299752
Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damageQ38320078
High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12.Q40388905
Hereditary Nonpolyposis Colorectal Cancer: the Syndrome, the Genes, and Historical PerspectivesQ40482404
Mismatch repair, genetic stability and tumour avoidanceQ40522939
Monoallelic mutation analysis (MAMA) for identifying germline mutationsQ41306100
Mismatch Repair Deficiency in Phenotypically Normal Human CellsQ41347026
DNA loop repair by human cell extractsQ41429743
The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiaeQ41430030
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Clues to the pathogenesis of familial colorectal cancerQ42622043
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformationQ46049171
Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC)Q48075190
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutantsQ50192890
CpG dinucleotides in the hMSH2 and hMLH1 genes are hotspots for HNPCC mutations.Q55066383
A frequent hMSH2 mutation in hereditary non-polyposis colon cancer syndromeQ57266935
Better survival rates in patients with MLH1-associated hereditary colorectal cancerQ57567998
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patientsQ57570041
Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancerQ58862199
Mismatch correction at O 6 -methylguanine residues in E. coli DNAQ59049241
The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)Q62978412
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomasQ70972741
P433issue4
P921main subjectcolorectal cancerQ188874
P304page(s)755-772
P577publication date1996-12-01
P1433published inGastroenterology Clinics of North AmericaQ15756082
P1476titleDNA repair and colorectal cancer
P478volume25

Reverse relations

cites work (P2860)
Q35753544Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences
Q41005472Characterization of distinct human endometrial carcinoma cell lines deficient in mismatch repair that originated from a single tumor
Q40071695Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.
Q42633204Data sharing: Empty archives
Q53431346Genetic instability and chromosomal aberrations in colorectal cancer: a review of the current models.
Q41653205Genetic pathways to colorectal cancer
Q33836026Genomic and epigenetic instability in colorectal cancer pathogenesis
Q24685680Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon
Q35129256Mismatch repair proficiency and in vitro response to 5-fluorouracil
Q43761456Msh2 DNA mismatch repair gene deficiency and the food-borne mutagen 2-amino-1-methy1-6-phenolimidazo [4,5-b] pyridine (PhIP) synergistically affect mutagenesis in mouse colon
Q33378445Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair
Q42660015Replication errors: cha(lle)nging the genome
Q34989790The genetic pathogenesis of colorectal cancer
Q53428207Transient appearance of the mutator phenotype during carcinogenesis as a possible explanation for the lack of mini/microsatellite instability in many late stage tumors.
Q38336441hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

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