scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1021/BI00487A001 |
P953 | full work available at URL | https://pubs.acs.org/doi/pdf/10.1021/bi00487a001 |
P698 | PubMed publication ID | 1702019 |
P50 | author | Thomas A Kunkel | Q62517517 |
P433 | issue | 35 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | genetic model | Q67149661 |
DNA replication | Q130996 | ||
biochemistry | Q7094 | ||
P304 | page(s) | 8003-8011 | |
P577 | publication date | 1990-09-01 | |
1990-09-04 | |||
P1433 | published in | Biochemistry | Q764876 |
P1476 | title | Misalignment-mediated DNA synthesis errors | |
P478 | volume | 29 |
Q72012628 | 2–Aminofluorene modified DNA duplex exists in two interchangeable conformations |
Q30453467 | 3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1. |
Q34042634 | 8-Methoxypsoralen induced mutations are highly targeted at crosslinkable sites of photoaddition on the non-transcribed strand of a mammalian chromosomal gene |
Q67482102 | A 22-bp deletion in the phenylalanine hydroxylase gene causing phenylketonuria in an Arab family |
Q41973778 | A mechanism of nucleotide misincorporation during transcription due to template-strand misalignment |
Q35753566 | A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype |
Q42266867 | A molecular characterization of spontaneous frameshift mutagenesis within the trpA gene of Escherichia coli. |
Q49119301 | A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity |
Q64389525 | Analysis of spontaneous frameshift mutations in REV1 and rev1-1 strains of Saccharomyces cerevisiae |
Q40696088 | Antigen diversity in the bacterium B. hermsii through "somatic" mutations in rearranged vmp genes |
Q53768726 | Asymmetry of frameshift mutagenesis during leading and lagging-strand replication in Escherichia coli. |
Q34443496 | Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae |
Q58074430 | Bi-directional Processing of DNA Loops by Mismatch Repair-dependent and -independent Pathways in Human Cells |
Q33962585 | Complex frameshift mutations mediated by plasmid pKM101: mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella. |
Q57263791 | Complex gene rearrangements caused by serial replication slippage |
Q33491775 | Complexity of the MSG gene family of Pneumocystis carinii |
Q30424775 | Conditional reduction of human immunodeficiency virus type 1 replication by a gain-of-herpes simplex virus 1 thymidine kinase function |
Q51906358 | CpG/CpNpG motifs in the coding region are preferred sites for mutagenesis in the breast cancer susceptibility genes. |
Q43883867 | DNA end joining by the Klenow fragment of DNA polymerase I. |
Q28277408 | DNA polymerase fidelity and the polymerase chain reaction |
Q53105718 | DNA polymerase kappa microsatellite synthesis: two distinct mechanisms of slippage-mediated errors. |
Q74164952 | DNA polymerases on the move |
Q41264767 | DNA repair and colorectal cancer |
Q35677447 | DNA replication fidelity |
Q38332697 | DNA secondary structure effects on DNA synthesis catalyzed by HIV-1 reverse transcriptase |
Q24548004 | DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiae |
Q33962568 | DNA sequence effects on single base deletions arising during DNA polymerization in vitro by Escherichia coli Klenow fragment polymerase |
Q33692307 | DNA-directed mutations. Leading and lagging strand specificity |
Q37263073 | Damage, repair, and mutagenesis in nuclear genes after mouse forebrain ischemia-reperfusion |
Q34868968 | Database of p53 gene somatic mutations in human tumors and cell lines |
Q54455718 | De novo mutations in familial adenomatous polyposis (FAP). |
Q35975501 | Deletion between direct repeats in T7 DNA stimulated by double-strand breaks |
Q34973894 | Deletion mutations caused by DNA strand slippage in Acinetobacter baylyi |
Q50123699 | Deletogenic activity of 1,2:7,8-diepoxyoctane in the Salmonella typhimurium tester strain TA102. |
Q33886145 | Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors |
Q35562130 | Differences in genome-wide repeat sequence instability conferred by proofreading and mismatch repair defects |
Q35591486 | Differential DNA secondary structure-mediated deletion mutation in the leading and lagging strands |
Q40393541 | Discordant expression and variable numbers of neighboring GGA- and GAA-rich triplet repeats in the 3' untranslated regions of two groups of messenger RNAs encoded by the rat polymeric immunoglobulin receptor gene |
Q36754737 | Distinct mutational behaviors differentiate short tandem repeats from microsatellites in the human genome |
Q33862468 | Does variation in genome sizes reflect adaptive or neutral processes? New clues from Passiflora |
Q34310677 | EGNAS: an exhaustive DNA sequence design algorithm |
Q43882514 | Effects of a guanine-derived formamidopyrimidine lesion on DNA replication: translesion DNA synthesis, nucleotide insertion, and extension kinetics |
Q33807866 | Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase |
Q40393707 | Efficient extension of a misaligned tRNA-primer during replication of the HIV-1 retrovirus |
Q33566378 | Energetic signatures of single base bulges: thermodynamic consequences and biological implications. |
Q35598571 | Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit |
Q33994529 | Escherichia coli DNA polymerase IV mutator activity: genetic requirements and mutational specificity |
Q38305884 | Examination of the long-range effects of aminofluorene-induced conformational heterogeneity and its relevance to the mechanism of translesional DNA synthesis |
Q37593054 | Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age. |
Q71245633 | Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III |
Q35020670 | Fidelity and mutational spectrum of Pfu DNA polymerase on a human mitochondrial DNA sequence |
Q24628707 | Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH |
Q88499445 | Forensic applicability of multi-allelic InDels with mononucleotide homopolymer structures |
Q35748265 | Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae. |
Q41182021 | Gene deletions causing human genetic disease: mechanisms of mutagenesis and the role of the local DNA sequence environment |
Q35588912 | Genetic evidence that both dNTP-stabilized and strand slippage mechanisms may dictate DNA polymerase errors within mononucleotide microsatellites |
Q28264035 | Genetic instability in budding and fission yeast-sources and mechanisms |
Q41886362 | Genetic instability within monotonous runs of CpG sequences in Escherichia coli |
Q36627910 | Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools. |
Q36621522 | High rates of frameshift mutations within homo-oligomeric runs during a single cycle of retroviral replication. |
Q34467256 | High-frequency phenotypic reversion and pathogenicity of an acyclovir-resistant herpes simplex virus mutant |
Q34964296 | Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis |
Q73093633 | Homonucleotide tracts, short repeats and CpG/CpNpG motifs are frequent sites for heterogeneous mutations in the neurofibromatosis type 1 (NF1) tumour-suppressor gene |
Q34055705 | Human base excision repair creates a bias toward -1 frameshift mutations |
Q71937474 | Identification of a novel mutation causing aspartylglucosaminuria reveals a mutation hotspot region in the aspartylglucosaminidase gene |
Q40988373 | In situ detection of frameshift mutations in mouse cells |
Q45770163 | In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic |
Q37289159 | In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. |
Q35824007 | In vitro molecular reconstitution of the respiratory burst in B lymphoblasts from p47-phox-deficient chronic granulomatous disease |
Q33811519 | In vivo analysis of human T-cell leukemia virus type 1 reverse transcription accuracy |
Q35847997 | Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis |
Q34617609 | Is the rate of insertion and deletion mutation male biased?: Molecular evolutionary analysis of avian and primate sex chromosome sequences. |
Q33401963 | Large-scale inference of the point mutational spectrum in human segmental duplications |
Q40980167 | Lead and mercury mutagenesis: type of mutation dependent upon metal concentration |
Q34385155 | Lesion bypass DNA polymerases replicate across non-DNA segments |
Q29619994 | Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase |
Q27659842 | Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4 |
Q42044589 | Mechanisms of dinucleotide repeat instability in Escherichia coli |
Q30912512 | Mechanistic aspects of CoII(HAPP)(TFA)2 in DNA bulge-specific recognition. |
Q45755067 | Methods for the detection of non-random base substitution in virus genes: models of synonymous nucleotide substitution in picornavirus genes |
Q40022200 | Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes |
Q43612705 | Mismatch repair and the regulation of phase variation in Neisseria meningitidis |
Q41170340 | Mismatch repair defects in human carcinogenesis |
Q27323040 | Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase. |
Q73457782 | Molecular mechanisms of mutagenesis by aromatic amines and amides |
Q48076731 | Molecular nature of spontaneous mutations at the hypoxanthine-guanine phosphoribosyltransferase (hprt) locus in Chinese hamster ovary cells |
Q36796836 | Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequency and altered spectrum in a xeroderma pigmentosum variant |
Q46447125 | Mutagenicity of a Model DNA-Peptide Cross-Link in Human Cells: Roles of Translesion Synthesis DNA Polymerases |
Q39716050 | Mutation spectra of TA*, the major photoproduct of thymidylyl-(3'5')-deoxyadenosine, in Escherichia coli under SOS conditions |
Q54583351 | Mutational and DNA binding specificity of the carcinogen 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline. |
Q72519717 | Mutational spectrum induced in Saccharomyces cerevisiae by the carcinogen N-2-acetylaminofluorene |
Q41499457 | Mutational spectrum of ICR-191 at the hprt locus in human lymphoblastoid cells |
Q73019259 | Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity |
Q33180107 | Mutations induced by some DNA minor groove binding alkylators in AS52 Chinese hamster cells |
Q73687941 | Mutations of p53 gene in human colorectal cancer: distinct frameshifts among populations |
Q54588472 | N-ethyl-N-nitrosourea-induced mutagenesis in Escherichia coli: Multiple roles for UmuC protein |
Q34120857 | Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication |
Q44605177 | Nick-dependent and -independent processing of large DNA loops in human cells |
Q48165910 | Nucleotide sequence analysis of human hypoxanthine phosphoribosyltransferase (HPRT) gene deletions |
Q37191829 | On the origins of genetic variants |
Q35226155 | On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease |
Q54642988 | Oxygen radical induced mutagenesis is DNA polymerase specific. |
Q40637670 | Paradoxical homozygous expression from heterozygotes and heterozygous expression from homozygotes as a consequence of transcriptional infidelity through a polyadenine tract in the AP3B1 gene responsible for canine cyclic neutropenia. |
Q48061099 | Poly(T) variation in heteroderid nematode mitochondrial genomes is predominantly an artefact of amplification |
Q53766409 | Polymerase chain reaction-directed DNA sequencing of bleomycin-induced "nondeletion"-type, 6-thioguanine-resistant mutants in Chinese hamster ovary cell derivative AS52: effects of an inhibitor and a mimic of superoxide dismutase. |
Q47951603 | Pooled analysis of p53 mutations in hematological malignancies |
Q72679753 | Population screening of lactate dehydrogenase deficiencies in Fukuoka Prefecture in Japan and molecular characterization of three independent mutations in the lactate dehydrogenase-B(H) gene |
Q46595699 | Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli |
Q36483459 | RETRACTED: In vivo and in vitro evidence for slipped mispairing in mammalian mitochondria |
Q44920681 | Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain. |
Q39719038 | Replication bypass and mutagenic effect of alpha-deoxyadenosine site-specifically incorporated into single-stranded vectors |
Q42660015 | Replication errors: cha(lle)nging the genome |
Q73555611 | Replication of template-primers containing propanodeoxyguanosine by DNA polymerase beta. Induction of base pair substitution and frameshift mutations by template slippage and deoxynucleoside triphosphate stabilization |
Q35468354 | Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions |
Q34323549 | Ribosomal protein gene sequence changes in erythromycin-resistant mutants of Escherichia coli |
Q74643959 | Screening for mutations of the APC gene in 66 Italian familial adenomatous polyposis patients: evidence for phenotypic differences in cases with and without identified mutation |
Q41552163 | Selection for spontaneous null mutations in a chromosomally-integrated HSV-1 thymidine kinase gene yields deletions and a mutation caused by intragenic illegitimate recombination |
Q42641512 | Sequence polymorphism in the E3 7.7K ORF of subspecies B1 human adenoviruses |
Q24657452 | Sequence variation in the Fanconi anemia gene FAA |
Q59070212 | Slippery DNA and diseases |
Q34587260 | Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation |
Q41540380 | Spectrum of spontaneous mutation in animal cells containing an aphidicolin-resistant DNA polymerase α |
Q33952945 | Spontaneous microdeletions and microinsertions in a transgenic mouse mutation detection system: analysis of age, tissue, and sequence specificity |
Q73606010 | Spontaneous mutation of the lacI transgene in rodents: absence of species, strain, and insertion-site influence |
Q39718894 | Substitution and deletion mutations induced by 2-hydroxyadenine in Escherichia coli: effects of sequence contexts in leading and lagging strands |
Q71921084 | Tandem sequence duplications functionally complement deletions in the D1 protein of photosystem II |
Q77172508 | The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro |
Q72073105 | The effect of the 3′ → 5′ exonuclease of T7 DNA polymerase on frameshifts and deletions |
Q35749719 | The gateway pDEST17 expression vector encodes a -1 ribosomal frameshifting sequence |
Q33961004 | The influence of primary and secondary DNA structure in deletion and duplication between direct repeats in Escherichia coli |
Q35757863 | The mode and tempo of genome size evolution in eukaryotes. |
Q77231587 | The mutagenesis proteins UmuD' and UmuC prevent lethal frameshifts while increasing base substitution mutations |
Q34551905 | The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells |
Q35902590 | The roles of Tyr391 and Tyr619 in RB69 DNA polymerase replication fidelity |
Q47233090 | The size difference between leishmania major friedlin chromosome one homologues is localized to sub-telomeric repeats at one chromosomal end. |
Q47356449 | The size distribution of insertions and deletions in human and rodent pseudogenes suggests the logarithmic gap penalty for sequence alignment |
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Q72902049 | Transcribed heteroplasmic repeated sequences in the porcine mitochondrial DNA D-loop region |
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