| Q37219299 | 2002 William Allan Award Address. Inherited human diseases: victories, challenges, disappointments |
| Q35997274 | A case of colonic mucinous adenocarcinoma in 19-year-old male patient |
| Q36351943 | A de novo germline MLH1 mutation in a Lynch syndrome patient with discordant immunohistochemical and molecular biology test results. |
| Q47980414 | A germline missense mutation in exon 3 of the MSH2 gene in a Lynch syndrome family: correlation with phenotype and localization assay |
| Q54703592 | A large MSH2 Alu insertion mutation causes HNPCC in a German kindred. |
| Q63391845 | A missense germline mutation in exon 7 of the MSH2 gene in a HNPCC family from center-Italy |
| Q43199969 | A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening |
| Q77668057 | A modified multiplex PCR assay for detection of large deletions in MSH2 and MLH1 |
| Q48118231 | A multi-gene panel study in hereditary breast and ovarian cancer in Colombia. |
| Q79909235 | A new variant database for mismatch repair genes associated with Lynch syndrome |
| Q44095031 | A novel MSH2 germline mutation in a Druze HNPCC family |
| Q79858923 | A novel MSH2 mutation in a Chinese family with hereditary non-polyposis colorectal cancer |
| Q37089839 | A novel deleterious c.2656G>T MSH2 germline mutation in a Pakistani family with a phenotypic overlap of hereditary breast and ovarian cancer and Lynch syndrome |
| Q60458165 | A population based cohort study of patients with multiple colon and endometrial cancer: Correlation of microsatellite instability (msi) status, age at diagnosis and cancer risk |
| Q79732764 | A population-based audit for diagnosing colorectal cancer |
| Q90843197 | A practical guide to biomarkers for the evaluation of colorectal cancer |
| Q38267932 | A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment. |
| Q33269177 | A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer |
| Q28283356 | A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer |
| Q35013990 | A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory |
| Q34093711 | A role for MLH3 in hereditary nonpolyposis colorectal cancer |
| Q41625837 | A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America. |
| Q43893519 | ACMG technical standards and guidelines for genetic testing for inherited colorectal cancer (Lynch syndrome, familial adenomatous polyposis, and MYH-associated polyposis). |
| Q37383704 | APC mutations in colorectal tumors with mismatch repair deficiency |
| Q33811768 | Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency |
| Q47414442 | Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome |
| Q36115708 | Absence of somatic alterations of the EB1 gene adenomatous polyposis coli-associated protein in human sporadic colorectal cancers |
| Q83172998 | Adrenocortical carcinoma, an unusual extracolonic tumor associated with Lynch II syndrome |
| Q38798530 | Advances in Hereditary Colorectal and Pancreatic Cancers |
| Q42011353 | Age and origin of two common MLH1 mutations predisposing to hereditary colon cancer |
| Q39579538 | Altered microsatellites in incomplete-type intestinal metaplasia adjacent to primary gastric cancers |
| Q53465106 | An Alu VpA marker on chromosome I demonstrates that replication errors manifest at the adenoma-carcinoma transition in sporadic colorectal tumors. |
| Q73210133 | An early stage small bowel adenocarcinoma with microsatellite instability phenotype in a case of hereditary nonpolyposis colorectal cancer |
| Q37217323 | An economic viewpoint on alternative strategies for identifying persons with hereditary nonpolyposis colorectal cancer |
| Q35594366 | An insight into the genetic pathway of adenocarcinoma of the small intestine |
| Q36160898 | An unusual case of Turcot's syndrome associated with ileal adenocarcinoma, intestinal non-Hodgkin's lymphoma, and duodenal adenocarcinoma. Review of the classification and genetic basis of Turcot's syndrome |
| Q41376773 | An update of HNPCC (Lynch syndrome). |
| Q36308977 | Analysis for phenotype of HNPCC in China |
| Q42241844 | Analysis of Ha-ras 1 allele frequencies in hereditary non-polyposis colorectal cancer |
| Q83254020 | Analysis of colorectal cancer morphology in relation to sex, age, location, and family history |
| Q57570041 | Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients |
| Q61195888 | Analysis of telomere dynamics in peripheral blood cells from patients with Lynch syndrome |
| Q38360916 | Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing. |
| Q35560811 | Anticipation in lynch syndrome: where we are where we go |
| Q34088809 | Application of molecular diagnostics for the detection of Lynch syndrome |
| Q39042915 | Approach to Lynch Syndrome for the Gastroenterologist. |
| Q34041422 | Approach to early-onset colorectal cancer: clinicopathological, familial, molecular and immunohistochemical characteristics |
| Q47590011 | Assessing the predictive accuracy of hMLH1 and hMSH2 mutation probability models |
| Q47278309 | Association of colonic and endometrial carcinomas in Portuguese families with hereditary nonpolyposis colorectal carcinoma significantly increases the probability of detecting a pathogenic mutation in mismatch repair genes, primarily the MSH2 gene. |
| Q24539206 | Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations. |
| Q46764474 | Awareness of gynecologic surveillance in women from hereditary non-polyposis colorectal cancer families |
| Q37615625 | BRAF mutation in multiple primary cancer with colorectal cancer and stomach cancer |
| Q35446668 | BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing |
| Q57200503 | BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes |
| Q84551315 | Bethesda criteria for microsatellite instability testing: impact on the detection of new cases of Lynch syndrome |
| Q36559540 | Bibliometric analysis of the top-cited gastroenterology and hepatology articles |
| Q36245422 | Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases |
| Q93159881 | Broadening risk profile in familial colorectal cancer type X; increased risk for five cancer types in the national Danish cohort |
| Q30484460 | Building a tool to identify risk for Lynch syndrome among individuals presenting for screening colonoscopy |
| Q37399783 | Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome |
| Q38643822 | Cancer Risk in Families Fulfilling the Amsterdam Criteria for Lynch Syndrome |
| Q34346199 | Cancer genetics in oncology practice |
| Q35776962 | Cancer genetics services: a systematic review of the economic evidence and issues |
| Q61917173 | Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer |
| Q34992880 | Cancer risk assessment for the primary care physician |
| Q38100658 | Cancer risk in Lynch Syndrome |
| Q35566043 | Cancer risk in mismatch repair gene mutation carriers |
| Q57569922 | Cascade genetic testing for mismatch repair gene mutations |
| Q58862209 | Causes of microsatellite instability in colorectal tumors |
| Q35019094 | Cervical neuroendocrine tumor in a young female with Lynch Syndrome |
| Q33208352 | Challenges and pitfalls in HNPCC screening by microsatellite analysis and immunohistochemistry |
| Q33994353 | Characterisation of familial colorectal cancer Type X, Lynch syndrome, and non-familial colorectal cancer |
| Q47820449 | Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carcinoma. International Collaborative Group on HNPCC. |
| Q71970798 | Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer |
| Q54364278 | Characterization of germline mutations of MLH1 and MSH2 in unrelated south American suspected Lynch syndrome individuals. |
| Q34170508 | Chemoprevention in patients with genetic risk of colorectal cancers |
| Q57781636 | Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer |
| Q34320848 | Cigarette Smoking, Genetic Variants in Carcinogen-metabolizing Enzymes, and Colorectal Cancer Risk |
| Q57569926 | Classification of ambiguous mutations in DNA mismatch repair genes identified in a population-based study of colorectal cancer |
| Q42837936 | Classifying MMR variants: time for revised nomenclature in Lynch syndrome |
| Q58006247 | Clinical Definition of Hereditary Non-polyposis Colorectal Cancer: A Search for the Impossible? |
| Q37785236 | Clinical Genetics of Hereditary Colorectal Cancer |
| Q35799369 | Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome |
| Q34099201 | Clinical and molecular analysis of hereditary non-polyposis colorectal cancer in Chinese colorectal cancer patients |
| Q54343584 | Clinical and molecular detection of inherited colorectal cancers in northeast Italy: a first prospective study of incidence of Lynch syndrome and MUTYH-related colorectal cancer in Italy. |
| Q38024724 | Clinical correlation and molecular evaluation confirm that the MLH1 p.Arg182Gly (c.544A>G) mutation is pathogenic and causes Lynch syndrome. |
| Q36246482 | Clinical description of the Lynch syndrome [hereditary nonpolyposis colorectal cancer (HNPCC)]. |
| Q36065786 | Clinical features and mismatch repair gene mutation screening in Chinese patients with hereditary nonpolyposis colorectal carcinoma |
| Q30974845 | Clinical genetic counselling for familial cancers requires reliable data on familial cancer risks and general action plans |
| Q43238302 | Clinical guidelines versus universal molecular testing: are we ready to choose an optimal strategy for Lynch syndrome identification? |
| Q34382043 | Clinical heterogeneity of familial colorectal cancer and its influence on screening protocols. |
| Q62978110 | Clinical management of hereditary colorectal cancer syndromes |
| Q71073273 | Clinical manifestations in patients with hereditary nonpolyposis colorectal cancer |
| Q83333091 | Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations |
| Q35010430 | Clinical phenotype and prevalence of hereditary nonpolyposis colorectal cancer syndrome in Chinese population |
| Q38139284 | Clinical significance of microsatellite instability in colorectal cancer |
| Q36306668 | Clinico-pathologic Parameters for Prediction of Microsatellite Instability in Colorectal Cancer. |
| Q73969412 | Clinicopathologic and familial characteristics of endometrial carcinoma with multiple primary carcinomas in relation to the loss of protein expression of MSH2 and MLH1 |
| Q100524954 | Clinicopathologic characteristics and outcomes of endometrial Cancer patients with mismatch repair deficiency in the era of universal Lynch syndrome screening |
| Q35011402 | Clinicopathological and molecular genetic analysis of HNPCC in China |
| Q35954814 | Clinicopathological features and management of cancers in lynch syndrome |
| Q35550036 | Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families |
| Q34501594 | Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair |
| Q40671124 | Colon cancer connections. Cancer syndrome meets molecular biology meets histopathology |
| Q36372079 | Colon cancer: polyps, prevention, and politics |
| Q35596172 | Colonoscopy surveillance of individuals at risk of familial colorectal cancer |
| Q93917269 | Colorectal cancer |
| Q54583467 | Colorectal cancer in patients aged 30 years or younger. |
| Q37331121 | Colorectal cancer in the family: psychosocial distress and social issues in the years following genetic counselling |
| Q73234876 | Colorectal cancer screening |
| Q78732138 | Colorectal cancer screening |
| Q33714888 | Colorectal cancer screening: new opportunities. |
| Q34558166 | Colorectal cancer--what is standard surgery? |
| Q34844579 | Colorectal cancer: from epidemiology to current treatment |
| Q71726928 | Colorectal neoplasms detected colonoscopically in at-risk members of colorectal cancer families stratified by the demonstration of DNA microsatellite instability |
| Q95309234 | Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with lynch syndrome like metastatic colorectal cancer |
| Q61970275 | Combined use of MLPA and nonfluorescent multiplex PCR analysis by high performance liquid chromatography for the detection of genomic rearrangements |
| Q34308993 | Common hereditary cancers and implications for primary care |
| Q77413350 | Comparative genomic hybridization reveals differences in DNA copy number changes between sporadic gastric carcinomas and gastric carcinomas from patients with hereditary nonpolyposis colorectal cancer |
| Q36887649 | Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer. |
| Q51552333 | Comparison of clinical schemas and morphologic features in predicting Lynch syndrome in mutation-positive patients with endometrial cancer encountered in the context of familial gastrointestinal cancer registries. |
| Q34013017 | Complementary analysis of microsatellite tumor profile and mismatch repair defects in colorectal carcinomas |
| Q33677624 | Complex genetic predisposition to cancer in an extended HNPCC family with an ancestral hMLH1 mutation. |
| Q53361302 | Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations. |
| Q91818613 | Comprehensive mismatch repair gene panel identifies variants in patients with Lynch-like syndrome |
| Q37385768 | Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases |
| Q34017044 | Consequences of universal MSI/IHC in screening ENDOMETRIAL cancer patients for Lynch syndrome |
| Q83131182 | Consideration of hereditary nonpolyposis colorectal cancer in BRCA mutation-negative familial ovarian cancers |
| Q43614950 | Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast |
| Q40916028 | Contributions of the molecular biologist in gastrointestinal cancer and precancer screening: current possibilities and future prospects. |
| Q57567891 | Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer |
| Q35748966 | Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors |
| Q34102586 | Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer |
| Q33855528 | Cooperative nuclear localization sequences lend a novel role to the N-terminal region of MSH6. |
| Q37590426 | Copy number variation in hereditary non-polyposis colorectal cancer |
| Q53409371 | Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas. |
| Q35597163 | Cost effectiveness of a new strategy to identify HNPCC patients |
| Q37293563 | Could triaging family history of cancer during palliative care enable earlier genetic counseling intervention? |
| Q55066383 | CpG dinucleotides in the hMSH2 and hMLH1 genes are hotspots for HNPCC mutations. |
| Q35991337 | Creation of a network to promote universal screening for Lynch syndrome: the LynchSyndrome Screening Network |
| Q45898127 | Current Lynch syndrome tumor screening practices: a survey of genetic counselors. |
| Q47094355 | Current Tissue Molecular Markers in Colorectal Cancer: A Literature Review |
| Q37697538 | Current and future molecular diagnostics in colorectal cancer and colorectal adenoma. |
| Q33979656 | Current challenges in cancer screening. Part I. Colon cancer screening |
| Q34289520 | Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers |
| Q88621871 | Current clinical topics of Lynch syndrome |
| Q21328691 | Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients |
| Q35360590 | DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer. |
| Q36527421 | DNA mismatch repair and Lynch syndrome |
| Q34568596 | DNA mismatch repair defects: role in colorectal carcinogenesis |
| Q38713996 | DNA mismatch repair deficiency and hereditary syndromes in Latino patients with colorectal cancer |
| Q78054861 | DNA mismatch repair deficiency in curatively resected sextuple primary cancers in different organs: a molecular case report |
| Q33947053 | DNA mismatch repair genes and colorectal cancer |
| Q41264767 | DNA repair and colorectal cancer |
| Q26796491 | Deficient mismatch repair: Read all about it (Review) |
| Q71942323 | Detection of Tn, sialosyl-Tn and T antigens in hereditary nonpolyposis colorectal cancer |
| Q33318711 | Detection of mismatch repair gene germline mutation carrier among Chinese population with colorectal cancer |
| Q33682850 | Detection of new mutations in six out of 10 Swiss HNPCC families by genomic sequencing of the hMSH2 and hMLH1 genes |
| Q30484158 | Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy |
| Q35551054 | Diagnosis and Management of Hereditary Non-Polyposis Colon Cancer |
| Q34756013 | Diagnosis and management of hereditary colon cancer |
| Q34610509 | Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model |
| Q43004968 | Diagnosis of hereditary non-polyposis colorectal cancer (HNPCC). |
| Q71520203 | Diagnostic use of microsatellite instability in hereditary non-polyposis colorectal cancer |
| Q35748341 | Dietary phytoestrogen intake is associated with reduced colorectal cancer risk |
| Q37235042 | Differences and evolution of the methods for the assessment of microsatellite instability |
| Q50915480 | Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors. |
| Q35238626 | Different mechanisms underlie DNA instability in Huntington disease and colorectal cancer |
| Q41438646 | Differential expression of CK20, β-catenin, and MUC2/5AC/6 in Lynch syndrome and familial colorectal cancer type X |
| Q73498523 | Discordance of p53 mutations of synchronous colorectal carcinomas |
| Q48682503 | Disease expression in Swiss hereditary non-polyposis colorectal cancer (HNPCC) kindreds |
| Q44028985 | Distinct clinical features and outcomes of gastric cancers with microsatellite instability |
| Q34950524 | Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x. |
| Q34615912 | Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability |
| Q35595620 | Does a family history of cancer increase the risk of occurrence, growth, and recurrence of colorectal adenomas? |
| Q91943718 | Does breast carcinoma belong to the Lynch syndrome tumor spectrum? - Somatic mutational profiles vs. ovarian and colorectal carcinomas |
| Q46778172 | Does mutation of transforming growth factor-beta type II receptor gene play an important role in colorectal polyps? |
| Q33593851 | Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer? |
| Q59159730 | Does the occurrence of certain rare cancers indicate an inherited cancer susceptibility? |
| Q81977792 | Double primary malignancy in colorectal cancer patients--MSI is the useful marker for predicting double primary tumors |
| Q61814377 | Early-onset colorectal cancer in young individuals |
| Q37479736 | Early-onset colorectal cancer patients without family history are "at very low risk" for lynch syndrome |
| Q34207783 | Early-onset colorectal cancer: a sporadic or inherited disease? |
| Q33732330 | Economic and Practical Factors in Diagnosing HNPCC Using Clinical Criteria, Immunohistochemistry and Microsatellite Instability Analysis |
| Q30226781 | Effects of a decision support intervention on decisional conflict associated with microsatellite instability testing |
| Q35308706 | Elevated cancer mortality in the relatives of patients with pancreatic cancer |
| Q37236178 | Endometrial cancer as a familial tumor: pathology and molecular carcinogenesis (review). |
| Q64963004 | Endoscopic full thickness resection for early colon cancer in Lynch syndrome. |
| Q24596823 | Era of universal testing of microsatellite instability in colorectal cancer |
| Q44595115 | Estimating cancer risk in HNPCC by the GRL method. |
| Q30951811 | Estimating penetrance from family data using a retrospective likelihood when ascertainment depends on genotype and age of onset |
| Q35596787 | Estimation of the familial relative risk of cancer by site from a French population based family study on colorectal cancer (CCREF study). |
| Q36749671 | Evaluating Lynch syndrome in very early onset colorectal cancer probands without apparent polyposis |
| Q88009101 | Evaluation of MLH1 variants of unclear significance |
| Q36896145 | Evaluation of a new panel of six mononucleotide repeat markers for the detection of DNA mismatch repair-deficient tumours |
| Q27310710 | Evaluation of the Families SHARE workbook: an educational tool outlining disease risk and healthy guidelines to reduce risk of heart disease, diabetes, breast cancer and colorectal cancer |
| Q37454450 | Evaluation of the colorectal cancer risk conferred by rare UNC5C alleles. |
| Q88635627 | Evidence for GALNT12 as a moderate penetrance gene for colorectal cancer |
| Q51395876 | Evidence for breast cancer as an integral part of Lynch syndrome. |
| Q35603671 | Evidence of linkage to chromosomes 10p15.3-p15.1, 14q24.3-q31.1 and 9q33.3-q34.3 in non-syndromic colorectal cancer families |
| Q40491964 | Evolution of hereditary bowel cancer |
| Q36246478 | Evolution of the nomenclature for the hereditary colorectal cancer syndromes |
| Q37247809 | Evolving approach and clinical significance of detecting DNA mismatch repair deficiency in colorectal carcinoma. |
| Q77619057 | Excess of hMLH1 germline mutations in Swiss families with hereditary non-polyposis colorectal cancer |
| Q36641429 | Extensive molecular screening for hereditary non-polyposis colorectal cancer |
| Q51794323 | Extracolonic cancers associated with hereditary nonpolyposis colorectal cancer in the Utah Population Database. |
| Q36141256 | Extracolonic features of familial adenomatous polyposis in patients with sporadic colorectal cancer |
| Q37427872 | Extracolonic manifestations of hereditary colorectal cancer syndromes |
| Q33711113 | Facilitating informed decisions regarding microsatellite instability testing among high-risk individuals diagnosed with colorectal cancer |
| Q50233622 | Familial Colorectal Cancer Type X. |
| Q38943217 | Familial Colorectal Cancer: Understanding the Alphabet Soup |
| Q34578221 | Familial and inherited colorectal cancer: endoscopic screening and surveillance |
| Q36622868 | Familial colorectal adenocarcinoma and hereditary nonpolyposis colorectal cancer: a nationwide epidemiological study from Sweden |
| Q43152267 | Familial colorectal cancer |
| Q38205339 | Familial colorectal cancer type X: genetic profiles and phenotypic features. |
| Q24594612 | Familial colorectal cancer type X: the other half of hereditary nonpolyposis colon cancer syndrome |
| Q34655489 | Familial colorectal cancer, beyond Lynch syndrome |
| Q33931803 | Familial colorectal cancer: eleven years of data from a registry program in Switzerland |
| Q34571812 | Familial colorectal cancer: pathology and molecular characteristics |
| Q28145436 | Familial endometrial cancer in female carriers of MSH6 germline mutations |
| Q73837142 | Familial relative risk of colorectal cancer: a population-based study |
| Q41264786 | Familial risk and colorectal cancer |
| Q51058168 | Familial risk of colo-rectal cancer in a low incidence area in southern Italy. |
| Q41697780 | Family history of cancer in children and young adults with colorectal cancer |
| Q24813130 | Family history of colorectal cancer in Iran |
| Q54516617 | Family history of colorectal cancer in a Sweden county |
| Q37399513 | Family history of hormonal cancers and colorectal cancer risk: a case-control study conducted in Ontario |
| Q37103121 | Feasibility of screening for Lynch syndrome among patients with colorectal cancer |
| Q38737111 | Finding the needle in a haystack: identification of cases of Lynch syndrome with MLH1 epimutation |
| Q46468400 | First description of mutational analysis of MLH1, MSH2 and MSH6 in Algerian families with suspected Lynch syndrome |
| Q34297390 | Founding mutations and Alu-mediated recombination in hereditary colon cancer |
| Q57648706 | Frequency of Microsatellite Instability in Unselected Sebaceous Gland Neoplasias and Hyperplasias |
| Q54506604 | Frequency of extra-colonic tumors in hereditary nonpolyposis colorectal cancer (HNPCC) and familial colorectal cancer (FCC) Brazilian families: An analysis by a Brazilian Hereditary Colorectal Cancer Institutional Registry. |
| Q54416094 | Frequency of extracolonic tumors in Brazilian families with Lynch syndrome: analysis of a hereditary colorectal cancer institutional registry. |
| Q81149391 | Frequency of familial colon cancer and hereditary nonpolyposis colorectal cancer (Lynch syndrome) in a large population database |
| Q35594265 | Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients |
| Q35352538 | Frequency of replication errors in colorectal cancer and their association with family history |
| Q43825969 | Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability |
| Q77495184 | Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer |
| Q47713981 | Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae |
| Q80776609 | Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC |
| Q33599177 | Gastrointestinal polyposis syndromes |
| Q35885813 | Gender-Specific Aspects of Lynch Syndrome and Familial Adenomatous Polyposis |
| Q44745628 | Gene-environment interaction in hereditary nonpolyposis colorectal cancer with implications for diagnosis and genetic testing. |
| Q90321477 | Genetic Counseling and Surveillance Focused on Lynch Syndrome |
| Q47567327 | Genetic Gastric Cancer Susceptibility in the International Clinical Cancer Genomics Community Research Network |
| Q53626640 | Genetic counseling and cascade genetic testing in Lynch syndrome. |
| Q37798758 | Genetic counseling considerations in the evaluation of families for Lynch syndrome--a review |
| Q40413766 | Genetic counseling outcomes: perceived risk and distress after counseling for hereditary colorectal cancer |
| Q34713375 | Genetic counselling and testing for susceptibility to breast, ovarian and colon cancer: where are we today? |
| Q35355359 | Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomas |
| Q38297232 | Genetic instability occurs in the majority of young patients with colorectal cancer |
| Q33676566 | Genetic linkage analysis in hereditary non-polyposis colon cancer syndrome. |
| Q33711610 | Genetic pathways in colorectal and other cancers |
| Q57337198 | Genetic pathways in colorectal and other cancers |
| Q31464606 | Genetic predisposition and somatic diversification in tumor development and progression |
| Q34008801 | Genetic predisposition to colorectal cancer: where we stand and future perspectives |
| Q73343192 | Genetic susceptibility testing |
| Q33764029 | Genetic susceptibility to non-polyposis colorectal cancer |
| Q36666308 | Genetic testing for colon cancer |
| Q40371466 | Genetic testing for colon cancer among African-Americans in North Carolina |
| Q33649978 | Genetic testing for hereditary colorectal cancer |
| Q34533915 | Genetic testing for high-risk colon cancer patients |
| Q30936707 | Genetic transmission of colorectal cancer: exploratory data analysis from a population based registry |
| Q41136743 | Genetics of colorectal and breast cancer. |
| Q30513982 | Genetics, genomics, and cancer risk assessment: State of the Art and Future Directions in the Era of Personalized Medicine |
| Q36646164 | Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach |
| Q37514904 | Genomic instability and carcinogenesis: an update. |
| Q72649470 | Genomic instability occurs in colorectal carcinomas but not in adenomas |
| Q42013009 | Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas |
| Q51815161 | Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic. |
| Q33939068 | Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families |
| Q70951139 | Germ line mutations of hMSH2 and hMLH1 genes in Japanese families with hereditary nonpolyposis colorectal cancer (HNPCC): usefulness of DNA analysis for screening and diagnosis of HNPCC patients |
| Q34100062 | Germline MLH1 and MSH2 mutational spectrum including frequent large genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families: implications for genetic testing |
| Q52633302 | Germline MLH1, MSH2 and MSH6 variants in Brazilian patients with colorectal cancer and clinical features suggestive of Lynch Syndrome. |
| Q36677899 | Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts |
| Q37462507 | Germline PMS2 mutation screened by mismatch repair protein immunohistochemistry of colorectal cancer in Japan |
| Q45211308 | Germline hMLH1 promoter mutation in a Newfoundland HNPCC kindred |
| Q34138211 | Germline mutation of RPS20, encoding a ribosomal protein, causes predisposition to hereditary nonpolyposis colorectal carcinoma without DNA mismatch repair deficiency |
| Q83879718 | Germline mutations of the hMLH1 and hMSH2 mismatch repair genes in Belgian hereditary nonpolyposis colon cancer (HNPCC) patients |
| Q34526950 | Guidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers syndrome |
| Q36746989 | Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer). |
| Q50731723 | Gynecologic screening in hereditary nonpolyposis colorectal cancer |
| Q93493049 | HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review |
| Q35875965 | HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences |
| Q93493043 | Hereditary Colorectal Cancer (CRC) Program in Latvia |
| Q36014675 | Hereditary Colorectal Cancer: Genetics and Screening |
| Q33866105 | Hereditary Non-Polyposis Colorectal Cancer: the rise and fall of a confusing term |
| Q54983718 | Hereditary Nonpolyposis Colorectal Cancer and Cancer Syndromes: Recent Basic and Clinical Discoveries. |
| Q36101834 | Hereditary aspects of colon cancer |
| Q56928447 | Hereditary breast cancer |
| Q36990149 | Hereditary cancer registries improve the care of patients with a genetic predisposition to cancer: contributions from the Dutch Lynch syndrome registry |
| Q36968380 | Hereditary cancer-associated missense mutations in hMSH6 uncouple ATP hydrolysis from DNA mismatch binding |
| Q39787221 | Hereditary colorectal cancer and Lynch syndrome |
| Q35355789 | Hereditary colorectal cancer in the general population: from cancer registration to molecular diagnosis |
| Q34713100 | Hereditary colorectal cancer syndromes: molecular genetics, genetic counseling, diagnosis and management. |
| Q34045183 | Hereditary colorectal cancer: risk assessment and management |
| Q36198294 | Hereditary non-polyposis colon cancer |
| Q61757262 | Hereditary non-polyposis colorectal cancer (HNPCC): phenotype-genotype correlation between patients with and without identified mutation |
| Q73167197 | Hereditary non-polyposis colorectal cancer associated with disseminated superficial porokeratosis. Microsatellite instability in skin tumours |
| Q71652296 | Hereditary non-polyposis colorectal cancer — morphologies, genes and mutations |
| Q35889187 | Hereditary nonpolyposis colon cancer: analysis of linkage to 2p15-16 places the COCA1 locus telomeric to D2S123 and reveals genetic heterogeneity in seven Canadian families |
| Q74028591 | Hereditary nonpolyposis colorectal cancer |
| Q34648373 | Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome |
| Q36470055 | Hereditary nonpolyposis colorectal cancer and familial colorectal cancer in Central part of Iran, Isfahan. |
| Q79098523 | Hereditary nonpolyposis colorectal cancer and related conditions |
| Q42037545 | Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations |
| Q41045332 | Hereditary nonpolyposis colorectal cancer: review of clinical, molecular genetics, and counseling aspects |
| Q47301537 | Hereditary nonpolyposis colorectal carcinoma (HNPCC) and HNPCC-like families: Problems in diagnosis, surveillance, and management |
| Q34532533 | Hereditary polyposis syndromes and hereditary non-polyposis colorectal cancer |
| Q34952659 | Hereditary prostate cancer as a feature of Lynch syndrome |
| Q35029059 | Heritable colorectal cancer syndromes: recognition and preventive management |
| Q90192347 | High Prevalence of Alterations in DNA Mismatch Repair Genes of Lynch Syndrome in Pediatric Patients with Adrenocortical Tumors Carrying a Germline Mutation on TP53 |
| Q36808349 | High risk of colorectal and endometrial cancer in Ashkenazi families with the MSH2 A636P founder mutation |
| Q51123677 | High risk of endometrial cancer in colorectal cancer kindred is pathognomonic for MMR-mutation carriers. |
| Q35868041 | Highly penetrant hereditary cancer syndromes. |
| Q53296714 | History of the International Collaborative Group on Hereditary Non Polyposis Colorectal Cancer. |
| Q37716875 | History, genetics, and strategies for cancer prevention in Lynch syndrome |
| Q55465499 | Homozygosity of MSH2 c.1906G-->C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I. |
| Q37639436 | How do researchers manage genetic results in practice? The experience of the multinational Colon Cancer Family Registry |
| Q43002767 | Human mismatch-repair protein MutL homologue 1 (MLH1) interacts with Escherichia coli MutL and MutS in vivo and in vitro: a simple genetic system to assay MLH1 function |
| Q59274550 | Identificación de dos familias con cáncer de colon hereditario no polipósico (CCHNP) y criterios de Amsterdam. Relevancia del árbol genealógico y las medidas de seguimiento |
| Q60023148 | Identification and surveillance of 19 Lynch syndrome families in southern Italy: report of six novel germline mutations and a common founder mutation |
| Q37416078 | Identification of Lynch syndrome among patients with colorectal cancer |
| Q36179036 | Identification of Lynch syndrome: how should we proceed in the 21st century? |
| Q73073264 | Identification of families with hereditary breast and ovarian cancer for clinical and mammographic surveillance: the Modena Study Group proposal |
| Q49844031 | Identification of genetic variants for clinical management of familial colorectal tumors. |
| Q79073717 | Identification of germline MSH2 gene mutations in endometrial cancer not fulfilling the new clinical criteria for hereditary nonpolyposis colorectal cancer |
| Q37968220 | Identification of individuals at risk for Lynch syndrome using targeted evaluations and genetic testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer joint practice guideline |
| Q35760971 | Identification of mismatch repair gene mutations in young patients with colorectal cancer and in patients with multiple tumours associated with hereditary non-polyposis colorectal cancer. |
| Q36991821 | Identification of novel variants in colorectal cancer families by high-throughput exome sequencing |
| Q34652530 | Identification of patients at risk for hereditary colorectal cancer |
| Q34591199 | Identification of patients at-risk for Lynch syndrome in a hospital-based colorectal surgery clinic |
| Q57729078 | Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing |
| Q57291374 | Impact of colonoscopic screening in Familial Colorectal Cancer Type X |
| Q36392688 | Impact of genetic testing on endometrial cancer risk-reducing practices in women at risk for Lynch syndrome |
| Q47935364 | Importance of PCR-based Tumor Testing in the Evaluation of Lynch Syndrome-associated Endometrial Cancer |
| Q34368271 | Indian Council of Medical Research consensus document for the management of colorectal cancer |
| Q77900400 | Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer |
| Q41352120 | Inheritance and susceptibility to tumours of the large bowel: a new classification of colorectal malignancies. |
| Q37797701 | Inheritance of Epigenetic Aberrations (Constitutional Epimutations) in Cancer Susceptibility |
| Q42950076 | Inherited Colorectal Cancer Syndromes |
| Q37427523 | Inherited colorectal cancer syndromes |
| Q45345393 | Inherited deleterious variants in GALNT12 are associated with CRC susceptibility |
| Q57742300 | Inherited susceptibility to colorectal adenomas and carcinomas: Evidence for a new predisposition gene on 15q14-q22 |
| Q36494281 | Initiation of universal tumor screening for Lynch syndrome in colorectal cancer patients as a model for the implementation of genetic information into clinical oncology practice |
| Q47117168 | Integrating surgery and genetic testing for the modern surgeon. |
| Q54750794 | Intratumoral Heterogeneity in Microsatellite Alterations in BRCA1 and PTEN Regions in Sporadic Colorectal Cancer |
| Q40001844 | Intrusion and avoidance in subjects undergoing genetic investigation and counseling for hereditary cancer |
| Q42279768 | Involvement of APC and K-ras mutation in non-polypoid colorectal tumorigenesis |
| Q41397954 | Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study. |
| Q35954134 | Is surveillance of the small bowel indicated for Lynch syndrome families? |
| Q61196108 | K-ras andp53 mutations in hereditary non-polyposis colorectal cancers |
| Q34204951 | Little evidence for involvement of MLH3 in colorectal cancer predisposition |
| Q99408636 | Long-Lasting Response to Nivolumab for a Patient With Lynch Syndrome-Associated Lung Adenocarcinoma |
| Q58876485 | Loss of heterozygosity at 19p13.2 and 2q21 in tumours from familial clusters of non-medullary thyroid carcinoma |
| Q36308096 | Loss of heterozygosity on chromosome 1 in sporadic colorectal carcinoma |
| Q30396926 | Loss of heterozygosity on long arm of chromosome 22 in sporadic colorectal carcinoma |
| Q54760397 | Low mutation rate of hMSH2 and hMLH1 in Taiwanese hereditary non-polyposis colorectal cancer. |
| Q35777640 | Low prevalence of germline hMSH6 mutations in colorectal cancer families from Spain |
| Q24618839 | Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X |
| Q33920573 | Lower gastrointestinal tract cancer predisposition syndromes |
| Q35715466 | Lynch Syndrome Associated With PMS2 Mutation: Understanding Current Concepts |
| Q91852820 | Lynch Syndrome in Urologic Malignancies - What Does the Urologist Need to Know? |
| Q37328144 | Lynch syndrome (HNPCC). |
| Q36259687 | Lynch syndrome (hereditary non-polyposis colorectal cancer): current concepts and approaches to management |
| Q33653935 | Lynch syndrome among gynecologic oncology patients meeting Bethesda guidelines for screening |
| Q21256711 | Lynch syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old |
| Q36246487 | Lynch syndrome genes |
| Q83396199 | Lynch syndrome in Tunisia: first description of clinical features and germline mutations |
| Q37248283 | Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion |
| Q38084166 | Lynch syndrome-associated neoplasms: a discussion on histopathology and immunohistochemistry. |
| Q34347636 | Lynch syndrome: an updated review |
| Q37987828 | Lynch syndrome: clinical, pathological, and genetic insights |
| Q36492360 | Lynch syndrome: still not a familiar picture |
| Q74323855 | MLH1 and MSH2 constitutional mutations in colorectal cancer families not meeting the standard criteria for hereditary nonpolyposis colorectal cancer |
| Q64070087 | MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 years |
| Q34650716 | MLH1 promoter methylation frequency in colorectal cancer patients and related clinicopathological and molecular features |
| Q52680910 | MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques. |
| Q54419889 | MLPA mutation detection in Argentine HNPCC and FAP families. |
| Q36695748 | MSH6 missense mutations are often associated with no or low cancer susceptibility |
| Q74455966 | MSI in endometrial carcinoma: absence of MLH1 promoter methylation is associated with increased familial risk for cancers |
| Q35881396 | Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16 |
| Q36774429 | Malignant transformation of residual endometriosis following hysterectomy and bilateral salpingo-oophorectomy in a female patient from a family with hereditary non-polyposis colorectal cancer |
| Q34788235 | Management of colorectal cancer. |
| Q37271434 | Managing hereditary gastrointestinal cancer syndromes: the partnership between genetic counselors and gastroenterologists |
| Q26740310 | Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer |
| Q62978241 | Meat consumption and meat preparation in relation to colorectal adenomas among sporadic and HNPCC family patients in The Netherlands |
| Q43919200 | Mechanisms of pathogenicity in human MSH2 missense mutants. |
| Q47391804 | Metachronous colorectal cancer following segmental or extended colectomy in Lynch syndrome: a systematic review and meta-analysis. |
| Q61196002 | Methylation pattern of different regions of theMLH1 promoter and silencing of gene expression in hereditary and sporadic colorectal cancer |
| Q73104112 | Microsatellite analysis at 10q25-q26 in Sardinian patients with sporadic endometrial carcinoma: identification of specification patterns of genetic alteration |
| Q25257189 | Microsatellite instability analysis in hereditary non-polyposis colon cancer using the Bethesda consensus panel of microsatellite markers in the absence of proband normal tissue |
| Q35746560 | Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis |
| Q73719421 | Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma |
| Q33757624 | Microsatellite instability at tetranucleotide repeats in sporadic colorectal cancer in Japan. |
| Q83841411 | Microsatellite instability did not predict individual survival of unselected patients with colorectal cancer |
| Q53436328 | Microsatellite instability in Japanese hereditary non-polyposis colorectal cancer does not induce mutation of a simple repeat sequence of the bax gene. |
| Q24627393 | Microsatellite instability in colorectal cancer |
| Q28247135 | Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases |
| Q83835402 | Microsatellite instability in colorectal cancer: from molecular oncogenic mechanisms to clinical implications |
| Q73554869 | Microsatellite instability in colorectal-cancer patients with suspected genetic predisposition |
| Q33678081 | Microsatellite instability in early onset and familial colorectal cancer. |
| Q35557578 | Microsatellite instability in patients with multiple primary cancers of the gastrointestinal tract |
| Q73112583 | Microsatellite instability is rare in rectal carcinomas and signifies hereditary cancer |
| Q36124008 | Microsatellite instability testing and its role in the management of colorectal cancer. |
| Q35355631 | Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer |
| Q34217505 | Microsatellite instability: application in hereditary non-polyposis colorectal cancer. |
| Q43864989 | Milestones of Lynch syndrome: 1895-2015. |
| Q36540568 | Mismatch repair defects and Lynch syndrome: The role of the basic scientist in the battle against cancer |
| Q72127255 | Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability |
| Q36607065 | Modern challenges in colorectal cancer. |
| Q41759485 | Molecular advances in the etiology and treatment of colorectal cancer |
| Q33904639 | Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene |
| Q37360286 | Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant |
| Q41686589 | Molecular biology of colorectal cancer |
| Q57316220 | Molecular characterization of the spectrum of genomic deletions in the mismatch repair genesMSH2,MLH1,MSH6, andPMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC) |
| Q33670210 | Molecular diagnostics of cancer predisposition: hereditary non-polyposis colorectal carcinoma and mismatch repair defects |
| Q33540554 | Molecular genetics of gastrointestinal malignancies |
| Q37680161 | Molecular genetics of microsatellite-unstable colorectal cancer for pathologists |
| Q35433209 | Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer |
| Q28214396 | Mouse models for human DNA mismatch-repair gene defects |
| Q36661641 | Mucinous carcinoma of the duodenum associated with hereditary nonpolyposis colorectal cancer: report of a case |
| Q34386209 | Muir-Torre phenotype has a frequency of DNA mismatch-repair-gene mutations similar to that in hereditary nonpolyposis colorectal cancer families defined by the Amsterdam criteria |
| Q73499371 | Muir-Torre syndrome: clinical features and molecular genetic analysis |
| Q54938040 | Multiple primary cancers with microsatellite instability: report of a case. |
| Q38109835 | Multivariate analysis of MLH1 c.1664T>C (p.Leu555Pro) mismatch repair gene variant demonstrates its pathogenicity. |
| Q42026314 | Mutation screening of MSH2 and MLH1 mRNA in hereditary non-polyposis colon cancer syndrome |
| Q37522727 | Mutation spectrum in South American Lynch syndrome families |
| Q81602162 | Mutational analysis of hMsh6 in Israeli HNPCC and HNPCC-like families |
| Q71970804 | Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instability |
| Q79198177 | Mutations of the 'minor' mismatch repair gene MSH6 in typical and atypical hereditary nonpolyposis colorectal cancer |
| Q28235642 | Mutations predisposing to hereditary nonpolyposis colorectal cancer |
| Q41099814 | Mutator genes and mosaicism in colorectal cancer |
| Q53401359 | No major difference in K-ras and p53 abnormalities in sporadic and hereditary nonpolyposis colorectal adenomas. |
| Q36080944 | Normal colonic mucosa in hereditary non-polyposis colorectal cancer shows no generalised increase in somatic mutation |
| Q35642022 | Novel MSH2 Mutation in the First Report of a Vietnamese-American Kindred with Lynch Syndrome |
| Q58695957 | Novel genetic mutations detected by multigene panel are associated with hereditary colorectal cancer predisposition |
| Q51819338 | Occult endometrial cancer and decision making for prophylactic hysterectomy in hereditary nonpolyposis colorectal cancer patients. |
| Q33930746 | Oral manifestations of hereditary nonpolyposis colorectal cancer syndrome: a family case series. |
| Q53885333 | PMS2 involvement in patients suspected of Lynch syndrome. |
| Q37247172 | PTEN germline mutations in patients initially tested for other hereditary cancer syndromes: would use of risk assessment tools reduce genetic testing? |
| Q35765148 | Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+ |
| Q33879359 | Parent of origin effects on age at colorectal cancer diagnosis |
| Q30906288 | Partial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers |
| Q37243606 | Past, present and future of colorectal cancer in the Kingdom of Saudi Arabia. |
| Q35594437 | Pathogenicity of missense and splice site mutations in hMSH2 and hMLH1 mismatch repair genes: implications for genetic testing |
| Q59273299 | Pathogenicity of the hereditary colorectal cancer mutation hMLH1 del616 linked to shortage of the functional protein |
| Q34102606 | Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study |
| Q42671419 | Patients at risk of familial colorectal cancer |
| Q36609603 | Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer |
| Q80060479 | Patients' and professionals' opinions of services for people at an increased risk of colorectal cancer: an exploratory qualitative study |
| Q36396727 | Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications |
| Q46324177 | Phenotypic and genotypic heterogeneity of Lynch syndrome: a complex diagnostic challenge |
| Q34520664 | Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome |
| Q36882484 | Prediction of germline mutations and cancer risk in the Lynch syndrome |
| Q62977764 | Prediction of the outcome of genetic testing in HNPCC kindreds using the revised Amsterdam criteria and immunohistochemistry |
| Q34155518 | Predictive models for mutations in mismatch repair genes: implication for genetic counseling in developing countries |
| Q70970972 | Predominance of normal karyotype in colorectal tumors from hereditary non-polyposis colorectal cancer patients |
| Q53421519 | Predominant germ-line mutation of the hMSH2 gene in Japanese hereditary non-polyposis colorectal cancer kindreds. |
| Q24653695 | Preoperative evaluation and oncologic principles of colon cancer surgery |
| Q73504243 | Preoperative treatment with tegafur suppositories enhances apoptosis and reduces the intratumoral microvessel density of human colorectal carcinoma |
| Q35022384 | Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers |
| Q57591232 | Prevalence of germline mutations ofMLH1 andMSH2 in hereditary nonpolyposis colorectal cancer families from Spain |
| Q38161230 | Prevalence of occult gynecologic malignancy at the time of risk reducing and nonprophylactic surgery in patients with Lynch syndrome |
| Q77738383 | Prevalence of the I1307K APC gene variant in Israeli Jews of differing ethnic origin and risk for colorectal cancer |
| Q34190072 | Preventive surgery for colon cancer in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer syndrome |
| Q33868034 | Primary signet-ring cell carcinoma of the colon at early stage: a case report and a review of the literature |
| Q74133434 | Proapoptotic gene BAX is frequently mutated in hereditary nonpolyposis colorectal cancers but not in adenomas |
| Q73784640 | Probable involvement of a germ-line mutation of an unknown mismatch repair gene in a Japanese Muir-Torre syndrome phenotype |
| Q36352432 | Proficiency of DNA repair genes and microsatellite instability in operated colorectal cancer patients with clinical suspicion of lynch syndrome |
| Q36629408 | Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal? |
| Q47962679 | Promoter analysis of the human mismatch repair gene hMSH2. |
| Q37834463 | Prophylactic surgery in Lynch syndrome |
| Q85155982 | Prospective Immunohistochemical Analysis of Primary Colorectal Cancers for Loss of Mismatch Repair Protein Expression |
| Q35594413 | Proximal adenomas in hereditary non-polyposis colorectal cancer are prone to rapid malignant transformation |
| Q58408439 | Prédispositions héréditaires au cancer colorectal |
| Q81886564 | Psycho-social counselling in predictive genetic testing for cancer: the association between number of supportive sessions and client characteristics as assessed by psycho-social workers |
| Q50997016 | Psychologic distress after disclosure of genetic test results regarding hereditary nonpolyposis colorectal carcinoma. |
| Q38558424 | Psychological opportunities and hazards in predictive genetic testing for cancer risk |
| Q35054808 | Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: report of a case |
| Q35882089 | RNA-based mutation screening in hereditary nonpolyposis colorectal cancer |
| Q36484887 | Recently identified colon cancer predispositions: MYH and MSH6 mutations |
| Q92341139 | Recommended care and care adherence following a diagnosis of Lynch syndrome: a mixed-methods study |
| Q62978317 | Rectal Cancer Risk in Hereditary Nonpolyposis Colorectal Cancer After Abdominal Colectomy |
| Q34263782 | Rectal cancer in hereditary nonpolyposis colorectal cancer |
| Q81825652 | Recurring MLH1 deleterious mutations in unrelated Chinese Lynch syndrome families in Singapore |
| Q37362198 | Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk |
| Q35249014 | Reduced frequency of extracolonic cancers in hereditary nonpolyposis colorectal cancer families with monoallelic hMLH1 expression |
| Q74610810 | Reduction in hMSH2 mRNA levels by premature translation termination: implications for mutation screening in hereditary nonpolyposis colorectal cancer |
| Q35444793 | Referral for cancer genetics consultation: a review and compilation of risk assessment criteria |
| Q36178900 | Refinement of heterozygosity loss on chromosome 5p15 in sporadic colorectal cancer |
| Q48557053 | Reflections on a rural surgical practice: the trip of a lifetime |
| Q35607535 | Relationship between DNA Mismatch Repair Deficiency and Endometrial Cancer |
| Q36642662 | Relationship of lower uterine segment cancer with Lynch syndrome: a novel case with an hMLH1 germline mutation |
| Q36316067 | Report of 16 kindreds and one kindred with hMLH1 germline mutation |
| Q47917318 | Results from an American Society of Colon and Rectal Surgeons survey on the management of young-onset colorectal cancer |
| Q33704556 | Results of a pilot study of endoscopic screening of first degree relatives of colorectal cancer patients in Italy |
| Q73412850 | Retroperitoneal liposarcoma in two siblings |
| Q34975833 | Review article: genetic testing and counselling for hereditary colorectal cancer |
| Q24610838 | Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications |
| Q35875374 | Risk assessment and screening for colorectal cancer. |
| Q36758605 | Risk assessment, genetic testing, and management of Lynch syndrome |
| Q36903207 | Risk of breast cancer in Lynch syndrome: a systematic review. |
| Q35428465 | Risk perception among Brazilian individuals with high risk for colorectal cancer and colonoscopy |
| Q58096541 | Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families |
| Q36621452 | Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome |
| Q36622905 | Role of chance in familial aggregation of colorectal cancer |
| Q50765059 | SISE matters: the sum of information on seventy-yr-old equivalents measures pedigree information content when assessing the risk of HNPCC in a family. |
| Q41563174 | Screening and surveillance for colorectal carcinoma |
| Q46946749 | Screening for Lynch syndrome in young Saudi colorectal cancer patients using microsatellite instability testing and next generation sequencing |
| Q34626113 | Screening for colon cancer and evaluation of chemoprevention with coxibs |
| Q73420426 | Screening for colorectal cancer |
| Q37160085 | Screening for germline mismatch repair mutations following diagnosis of sebaceous neoplasm |
| Q33775296 | Screening for mismatch repair deficiency in colorectal cancer: data from three academic medical centers. |
| Q55425174 | Screening for susceptibility genes in hereditary non-polyposis colorectal cancer. |
| Q41313487 | Screening of patients with a positive family history of colorectal cancer. |
| Q51772302 | Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation. |
| Q35435690 | Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. |
| Q24671692 | Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresis |
| Q42616545 | Single-amplicon MSH2 A636P mutation testing in Ashkenazi Jewish patients with colorectal cancer: role in presurgical management |
| Q44884428 | Somatic mosaicism and double somatic hits can lead to MSI colorectal tumors |
| Q36502627 | Somatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients |
| Q33722604 | Some aspects of molecular diagnostics in Lynch syndrome |
| Q47930955 | Subsequent primary malignancies after endometrial carcinoma and ovarian carcinoma |
| Q36262319 | Surgical management of colorectal cancer: A review of the literature |
| Q37939887 | Surgical management of hereditary nonpolyposis colorectal cancer |
| Q38090971 | Surgical treatment of hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome). |
| Q36246505 | Surveillance in Lynch syndrome |
| Q36919780 | Survival of hereditary non-polyposis colorectal cancer patients compared with sporadic colorectal cancer patients |
| Q35857243 | Synchronous primary cancers of the endometrium and ovary: a single institution review of 84 cases |
| Q35141950 | Systematic study on genetic and epimutational profile of a cohort of Amsterdam criteria-defined Lynch Syndrome in Singapore |
| Q37228468 | TGFBR1 variants TGFBR1(*)6A and Int7G24A are not associated with an increased familial colorectal cancer risk |
| Q41696433 | Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes. |
| Q76325357 | Testing guidelines for hereditary non-polyposis colorectal cancer |
| Q48332104 | The Changing Landscape of Lynch Syndrome due to PMS2 Mutations. |
| Q35360910 | The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea |
| Q37711787 | The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype |
| Q30501708 | The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history |
| Q37391248 | The association of tumor microsatellite instability phenotype with family history of colorectal cancer |
| Q34059188 | The cause of colorectal cancer |
| Q42573673 | The changing face of familial colorectal cancer |
| Q40606207 | The clinical and genetic manifestations of hereditary nonpolyposis colorectal carcinoma |
| Q24655454 | The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations |
| Q33805238 | The complexities of predictive genetic testing |
| Q36081288 | The effect of family size on estimates of the frequency of hereditary non-polyposis colorectal cancer. |
| Q34161196 | The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population |
| Q34020549 | The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas |
| Q34081267 | The genetic basis of Lynch syndrome and its implications for clinical practice and risk management |
| Q34618184 | The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease |
| Q38032859 | The genetic counselor: an important surgical ally in the optimal care of the cancer patient |
| Q34989790 | The genetic pathogenesis of colorectal cancer |
| Q38789406 | The genetic prediction of risk for gynecologic cancers. |
| Q41441057 | The genetics and natural history of hereditary colon cancer |
| Q73200819 | The genetics of colorectal cancer |
| Q40849233 | The genetics of inherited colon cancer |
| Q41194136 | The genotype of the human cancer cell: implications for risk analysis. |
| Q35608600 | The germline MLH1 K618A variant and susceptibility to Lynch syndrome-associated tumors |
| Q37038987 | The history of Lynch syndrome |
| Q37420429 | The identification of Lynch syndrome in British Columbia |
| Q43405021 | The impact of cancer pathology confirmation on clinical management of a family history of cancer |
| Q47157369 | The impact of hereditary cancer gene panels on clinical care and lessons learned |
| Q33595685 | The importance of family history in young patients with endometrial cancer. |
| Q34560535 | The incidence of Lynch syndrome |
| Q79198468 | The inframe MSH2 codon 596 deletion is linked with HNPCC and associated with lack of MSH2 protein in tumours |
| Q60449390 | The inherited nature of lung cancer: a pilot study |
| Q35037873 | The molecular and genetic basis of colon cancer |
| Q33822748 | The molecular biology of colorectal cancer development and the associated genetic events |
| Q34062115 | The mutational spectrum of Lynch syndrome in cyprus |
| Q90953408 | The practice of universal screening for Lynch syndrome in newly diagnosed endometrial carcinoma |
| Q100526148 | The relationship between BRCA-associated breast cancer and age factors: an analysis of the Japanese HBOC consortium database |
| Q44628695 | The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study |
| Q59548976 | The results of gynecologic surveillance in families with hereditary nonpolyposis colorectal cancer |
| Q34380045 | The revised Bethesda guidelines: extent of utilization in a university hospital medical center with a cancer genetics program |
| Q41193565 | The role of DNA repair in the prevention of cancer |
| Q38086720 | The role of epigenetics in Lynch syndrome |
| Q33912569 | The role of genetic screening and prophylactic surgery in surgical oncology |
| Q34792640 | The search for unaffected individuals with Lynch syndrome: do the ends justify the means? |
| Q77467844 | The value of microsatellite instability in the detection of HNPCC families and of sporadic colorectal cancers with special biological features: an investigation on a series of 100 consecutive cases |
| Q73855680 | There is no increase in frequency of somatic mutations in metastases compared with primary colorectal carcinomas with microsatellite instability |
| Q40597964 | Three new mutations in hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay |
| Q33298821 | Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families |
| Q36296721 | Tolerance of human MSH2+/- lymphoblastoid cells to the methylating agent temozolomide |
| Q77495206 | Transcripts with splicings of exons 15 and 16 of the hMLH1 gene in normal lymphocytes: implications in RNA-based mutation screening of hereditary non-polyposis colorectal cancer |
| Q37640727 | Translating clinical research of Molecular Biology into a personalized, multidisciplinary approach of colorectal cancer patients |
| Q46020269 | Tumor histology helps to identify Lynch syndrome among colorectal cancer patients. |
| Q54350048 | Two novel mutations in hMLH1 gene in Iranian hereditary non-polyposis colorectal cancer patients. |
| Q38646561 | Universal Screening of Colorectal Cancers for Lynch Syndrome: Challenges and Opportunities |
| Q33605565 | Universal molecular screening does not effectively detect Lynch syndrome in clinical practice |
| Q53519387 | Universal screening for Lynch syndrome among patients with colorectal cancer: patient perspectives on screening and sharing results with at-risk relatives. |
| Q36030785 | Universal tumor screening for Lynch syndrome: Assessment of the perspectives of patients with colorectal cancer regarding benefits and barriers |
| Q92129010 | Universal tumor screening for Lynch syndrome: Perceptions of Canadian pathologists and genetic counselors of barriers and facilitators |
| Q93345706 | Universal tumor screening for Lynch syndrome: perspectives of Canadian pathologists and genetic counselors |
| Q36990046 | Update on Lynch syndrome genomics |
| Q51421660 | Upper tract urothelial carcinomas: frequency of association with mismatch repair protein loss and lynch syndrome. |
| Q59272977 | Uroepithelial and kidney carcinoma in Lynch syndrome |
| Q38570349 | Using Genetics to Identify Hereditary Colorectal Polyposis and Cancer Syndromes in Your Patient |
| Q36024155 | Validation of an online questionnaire for identifying people at risk of familial and hereditary colorectal cancer |
| Q42287839 | Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants |
| Q50711835 | Very high incidence of familial colorectal cancer in Newfoundland: a comparison with Ontario and 13 other population-based studies. |
| Q57307281 | Very low incidence of microsatellite instability in rectal cancers from families at risk for HNPCC |
| Q36051960 | Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients. |
| Q74789011 | Why hereditary nonpolyposis colorectal carcinoma patients appear to have better survival than patients with sporadic colorectal carcinoma |
| Q47569384 | Working through a diagnostic challenge: colonic polyposis, Amsterdam criteria, and a mismatch repair mutation |
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