The history of Lynch syndrome

scientific article published on June 2013

The history of Lynch syndrome is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10689-013-9637-8
P932PMC publication ID3720817
P698PubMed publication ID23546821

P2093author name stringC Richard Boland
Henry T Lynch
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Mutations of two PMS homologues in hereditary nonpolyposis colon cancerQ24318484
Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancerQ24614511
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instabilityQ24618618
Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type XQ24618839
Microsatellite instability in colorectal cancerQ24627393
EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndromeQ24655053
Mutation of a mutL homolog in hereditary colon cancerQ28114939
Type, density, and location of immune cells within human colorectal tumors predict clinical outcomeQ28131662
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancerQ28253384
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancerQ28257360
Genetic mapping of a locus predisposing to human colorectal cancerQ28268634
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancerQ28289377
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cellsQ28292790
Mutations of GTBP in genetically unstable cellsQ28292802
The immune contexture in human tumours: impact on clinical outcomeQ29620667
Microsatellite instability in cancer of the proximal colonQ29620692
Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiencyQ33811768
Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancerQ33930691
Hereditary factors in cancer. Study of two large midwestern kindredsQ34241416
Report from the Jerusalem workshop on Lynch syndrome-hereditary nonpolyposis colorectal cancerQ34545510
Cancer family “G” revisited: 1895-1970Q34701495
Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndromeQ34901055
Mismatch repair proficiency and in vitro response to 5-fluorouracilQ35129256
Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trialQ35627411
Evolution of the nomenclature for the hereditary colorectal cancer syndromesQ36246478
Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletionQ37248283
Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reactionQ37265131
Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidineQ37357197
Hereditary Nonpolyposis Colorectal Cancer: the Syndrome, the Genes, and Historical PerspectivesQ40482404
Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.Q40582817
Conversion of diploidy to haploidyQ40897610
The role of DNA mismatch repair in platinum drug resistanceQ41155820
Loss of DNA mismatch repair in acquired resistance to cisplatinQ41189901
Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpointQ41303489
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutationQ41448577
Hypermutability and mismatch repair deficiency in RER+ tumor cellsQ41508298
Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.Q42607034
Clues to the pathogenesis of familial colorectal cancerQ42622043
History and molecular genetics of Lynch syndrome in family G: a century laterQ44082437
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
Origins of the Leeds Castle Polyposis GroupQ52859745
History of the International Collaborative Group on Hereditary Non Polyposis Colorectal Cancer.Q53296714
[Familial incidence of double malignancies]Q54447720
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.Q55033068
Heredity and adenocarcinoma of the colon.Q55493966
A family history of uterine and gastro-intestinal cancer.Q55509723
Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancerQ58862199
Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). I. Clinical description of resourceQ62772420
Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). II. Biomarker studiesQ62772424
MSH2 genomic deletions are a frequent cause of HNPCCQ62977773
The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)Q62978412
Familial colonic cancer without antecedent polyposisQ71317779
[Hereditary nature of cancers of the colon]Q72287592
Heredity and multiple primary malignant neoplasms: six cancer familiesQ72298705
FAMILIAL CANCER OF THE COLONQ76820704
[ON A CANCER FAMILY. A CONTRIBUTION TO THE PROBLEM OF THE HEREDITARY ASPECTS OF COLONIC CARCINOMA.]Q77107986
DOUBLE CANCER IN SIBLINGS. FAMILIAL ASSOCIATION OF CANCER OF THE GENITALIA AND INTESTINESQ78270857
FAMILIAL DISPOSITION OF CANCER OF THE GASTROINTESTINAL TRACTQ78527751
P433issue2
P304page(s)145-157
P577publication date2013-06-01
P1433published inFamilial CancerQ15761917
P1476titleThe history of Lynch syndrome
P478volume12

Reverse relations

cites work (P2860)
Q47210474Consequences of testing for mismatch repair deficiency of colorectal cancer in clinical practice
Q35601625Considerations and management of a patient with three metachronous cancers in association with Lynch syndrome and ileal Crohn's disease: A case report
Q45718448Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors.
Q37673618Historical Perspective on Familial Gastric Cancer.
Q52321073Immunohistochemistry for mismatch repair protein deficiency in endometrioid endometrial carcinoma yields equivalent results when performed on endometrial biopsy/curettage or hysterectomy specimens.
Q34347636Lynch syndrome: an updated review
Q36319705Mechanisms of glycosylase induced genomic instability
Q93079487Mismatch Recognition by Saccharomyces cerevisiae Msh2-Msh6: Role of Structure and Dynamics
Q38895750Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade
Q36540568Mismatch repair defects and Lynch syndrome: The role of the basic scientist in the battle against cancer
Q51116841Mismatch repair deficient-crypts in non-neoplastic colonic mucosa in Lynch syndrome: insights from an illustrative case.
Q38262826Mismatch repair genes founder mutations and cancer susceptibility in Lynch syndrome.
Q28084645New insights into the mechanism of DNA mismatch repair
Q42039194Novel Mutations in MLH1 and MSH2 Genes in Mexican Patients with Lynch Syndrome
Q27024662PMS2 monoallelic mutation carriers: the known unknown
Q40821149Recent discoveries in the molecular genetics of Lynch syndrome
Q53081522Recent progress in Lynch syndrome and other familial colorectal cancer syndromes.
Q48332104The Changing Landscape of Lynch Syndrome due to PMS2 Mutations.
Q34234950The evolution of colorectal cancer genetics-Part 2: clinical implications and applications

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