scholarly article | Q13442814 |
P356 | DOI | 10.1126/SCIENCE.8066446 |
P698 | PubMed publication ID | 8066446 |
P2093 | author name string | R D Kolodner | |
R M Liskay | |||
T A Prolla | |||
E Alani | |||
Q Pang | |||
P2860 | cites work | Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis | Q22122362 |
P433 | issue | 5175 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | ATP-binding mismatch repair protein YNL082W | Q27548136 |
Mismatch repair ATPase MLH1 YMR167W | Q27552202 | ||
DNA mismatch repair | Q2984243 | ||
P304 | page(s) | 1091-1093 | |
P577 | publication date | 1994-08-01 | |
P1433 | published in | Science | Q192864 |
P1476 | title | MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast | |
P478 | volume | 265 |
Q36744978 | A Whole Genome Screen for Minisatellite Stability Genes in Stationary-Phase Yeast Cells |
Q41313494 | A hPMS2 mutant cell line is defective in strand-specific mismatch repair |
Q33968472 | A mutation in a Saccharomyces cerevisiae gene (RAD3) required for nucleotide excision repair and transcription increases the efficiency of mismatch correction |
Q33772742 | A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype |
Q36540457 | A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair |
Q34792868 | A versatile scaffold contributes to damage survival via sumoylation and nuclease interactions |
Q28610858 | ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair |
Q35690218 | Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System |
Q33576170 | Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden |
Q34614513 | Analysis of conditional mutations in the Saccharomyces cerevisiae MLH1 gene in mismatch repair and in meiotic crossing over. |
Q57570041 | Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients |
Q38328409 | Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system. |
Q34088809 | Application of molecular diagnostics for the detection of Lynch syndrome |
Q73893732 | Arabidopsis MutS homologs-AtMSH2, AtMSH3, AtMSH6, and a novel AtMSH7-form three distinct protein heterodimers with different specificities for mismatched DNA |
Q36597002 | Beta clamp directs localization of mismatch repair in Bacillus subtilis |
Q34270970 | Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene |
Q38320783 | Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA. |
Q34606685 | CYS3, a hotspot of meiotic recombination in Saccharomyces cerevisiae. Effects of heterozygosity and mismatch repair functions on gene conversion and recombination intermediates. |
Q37302747 | Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract |
Q46691965 | Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants |
Q52946367 | Chemoresistant lung cancer stem cells display high DNA repair capability to remove cisplatin-induced DNA damage. |
Q24312177 | Cloning and expression analysis of a meiosis-specific MutS homolog: the human MSH4 gene |
Q28564557 | Cloning of the cDNA encoding rat homologue of the mismatch repair gene MSH2 and its expression during spermatogenesis |
Q37357197 | Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine |
Q34013017 | Complementary analysis of microsatellite tumor profile and mismatch repair defects in colorectal carcinomas |
Q33677624 | Complex genetic predisposition to cancer in an extended HNPCC family with an ancestral hMLH1 mutation. |
Q39652175 | Conservation of functional asymmetry in the mammalian MutLα ATPase |
Q36700756 | Construction of a human genomic library of clones containing poly(dG-dA).poly(dT-dC) tracts by Mg(2+)-dependent triplex affinity capture. DNA polymorphism associated with the tracts |
Q74701340 | DNA mismatch repair and cancer |
Q28211143 | DNA mismatch repair and mutation avoidance pathways |
Q34568596 | DNA mismatch repair defects: role in colorectal carcinogenesis |
Q41561505 | DNA mismatch repair gene mutations in human cancer |
Q33947053 | DNA mismatch repair genes and colorectal cancer |
Q41264767 | DNA repair and colorectal cancer |
Q74825124 | DNA repair in higher plants |
Q28709604 | DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae |
Q38331192 | DNA-dependent activation of the hMutSalpha ATPase |
Q28592891 | Different mutator phenotypes in Mlh1- versus Pms2-deficient mice |
Q27934236 | Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast |
Q36670109 | Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis |
Q43976820 | Distinct gene expression signatures in the striata of wild-type and heterozygous c-fos knockout mice following methamphetamine administration: evidence from cDNA array analyses |
Q45962906 | DnaN clamp zones provide a platform for spatiotemporal coupling of mismatch detection to DNA replication. |
Q38289639 | Dominant Saccharomyces cerevisiae msh6 mutations cause increased mispair binding and decreased dissociation from mispairs by Msh2-Msh6 in the presence of ATP. |
Q28534756 | Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway |
Q57272811 | Dual recognition–incision enzymes might be involved in mismatch repair and meiosis |
Q92203157 | Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex |
Q22248073 | Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2 |
Q28592033 | Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells |
Q27939116 | Eukaryotic DNA mismatch repair |
Q77753605 | Eukaryotic mismatch repair: an update |
Q39542069 | Evolutionary origin, diversification and specialization of eukaryotic MutS homolog mismatch repair proteins |
Q40473975 | Examination of Mitotic Recombination by Means of Hyper-recombination Mutants in Saccharomyces cerevisiae |
Q28261787 | Exonuclease 1-dependent and independent mismatch repair |
Q36431145 | Expression of the DNA mismatch repair proteins hMLH1 and hPMS2 in normal human tissues |
Q36641429 | Extensive molecular screening for hereditary non-polyposis colorectal cancer |
Q36568343 | Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins |
Q27931247 | Functional Differences and Interactions among the Putative RecA Homologs Rad51, Rad55, and Rad57 |
Q36083305 | Functional characterization of pathogenic human MSH2 missense mutations in Saccharomyces cerevisiae. |
Q36570003 | Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations |
Q34425450 | Functional interactions and signaling properties of mammalian DNA mismatch repair proteins |
Q27939611 | Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction |
Q27929951 | Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha. |
Q27932001 | Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. |
Q41355776 | Genetic control of microsatellite stability |
Q35318165 | Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1 |
Q43002767 | Human mismatch-repair protein MutL homologue 1 (MLH1) interacts with Escherichia coli MutL and MutS in vivo and in vitro: a simple genetic system to assay MLH1 function |
Q28140727 | Identification of mismatch repair protein complexes in HeLa nuclear extracts and their interaction with heteroduplex DNA |
Q24555745 | Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements |
Q33967139 | Inactivation of DNA mismatch repair by increased expression of yeast MLH1. |
Q28182219 | Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility |
Q36564802 | Influence of DNA sequence identity on efficiency of targeted gene replacement |
Q41352120 | Inheritance and susceptibility to tumours of the large bowel: a new classification of colorectal malignancies. |
Q24629057 | Interaction between the Msh2 and Msh6 nucleotide-binding sites in the Saccharomyces cerevisiae Msh2-Msh6 complex |
Q73923892 | Interaction of Escherichia coli MutS and MutL at a DNA mismatch |
Q24553992 | Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin |
Q33933718 | Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae |
Q28282791 | Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over |
Q39675432 | Isolation and characterization of new proliferating cell nuclear antigen (POL30) mutator mutants that are defective in DNA mismatch repair |
Q30724354 | MSIsensor: microsatellite instability detection using paired tumor-normal sequence data |
Q28510650 | Meiotic pachytene arrest in MLH1-deficient mice |
Q33952006 | Meiotic recombination frequencies are affected by nutritional states in Saccharomycescerevisiae |
Q33401080 | Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression |
Q35774020 | Microsatellite instability in preinvasive and invasive head and neck squamous carcinoma |
Q34217505 | Microsatellite instability: application in hereditary non-polyposis colorectal cancer. |
Q39715504 | Mismatch DNA recognition protein from an extremely thermophilic bacterium, Thermus thermophilus HB8 |
Q41347026 | Mismatch Repair Deficiency in Phenotypically Normal Human Cells |
Q33970449 | Mismatch repair in Schizosaccharomyces pombe requires the mutL homologous gene pms1: molecular cloning and functional analysis. |
Q34194518 | Mismatch repair in correction of replication errors and processing of DNA damage |
Q33967893 | Mismatch repair mutants in yeast are not defective in transcription-coupled DNA repair of UV-induced DNA damage. |
Q35057393 | Mismatch repair protein expression in colorectal cancer |
Q33984294 | Mismatch repair proteins and mitotic genome stability |
Q28271480 | Mismatch repair: mechanisms and relationship to cancer susceptibility |
Q37691675 | Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex |
Q47313905 | Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies |
Q48038727 | Mitochondrial DNA of the coral Sarcophyton glaucum contains a gene for a homologue of bacterial MutS: a possible case of gene transfer from the nucleus to the mitochondrion |
Q36557503 | Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae |
Q34293069 | Molecular mechanisms of DNA mismatch repair |
Q35433209 | Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer |
Q33739279 | Mouse models for colorectal cancer |
Q44522189 | Msh2 separation of function mutations confer defects in the initiation steps of mismatch repair |
Q28776215 | Multiple functions of MutS- and MutL-related heterocomplexes |
Q24548535 | Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae |
Q38337755 | MutS and MutL activate DNA helicase II in a mismatch-dependent manner |
Q24606421 | MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice |
Q42409924 | MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA. |
Q28592583 | Mutation in the mismatch repair gene Msh6 causes cancer susceptibility |
Q33842093 | Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae |
Q28235642 | Mutations predisposing to hereditary nonpolyposis colorectal cancer |
Q33957827 | Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations. |
Q33572538 | Normally lethal amino acid substitutions suppress an ultramutator DNA Polymerase δ variant |
Q34097342 | Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication |
Q33961620 | PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. |
Q34975960 | Pathogenesis and clinical management of hereditary non-polyposis colorectal cancer |
Q36733353 | Physical interaction between components of DNA mismatch repair and nucleotide excision repair |
Q24292177 | Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms |
Q33966617 | Poorly repaired mismatches in heteroduplex DNA are hyper-recombinagenic in Saccharomyces cerevisiae |
Q40434039 | Progress against cancer |
Q28142999 | Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex |
Q37319600 | Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins |
Q34608647 | Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes |
Q33865368 | Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae |
Q42660015 | Replication errors: cha(lle)nging the genome |
Q38336291 | Requirement for DNA mismatch repair proteins in the transcription-coupled repair of thymine glycols in Saccharomyces cerevisiae |
Q27939891 | Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis |
Q34554581 | Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs |
Q41099585 | Saccharomyces cerevisiae DNA repair processes: an update |
Q27931230 | Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs |
Q27932017 | Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair |
Q34610604 | Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae. |
Q33775500 | Sex and the single cell: meiosis in yeast |
Q34167290 | Single nucleotide polymorphisms of DNA mismatch repair genes MSH2 and MLH1 confer susceptibility to esophageal cancer |
Q41602506 | Strand-specific mismatch repair in mammalian cells |
Q34657088 | The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA. |
Q27935158 | The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations |
Q27930815 | The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs |
Q34604064 | The chromosome bias of misincorporations during double-strand break repair is not altered in mismatch repair-defective strains of Saccharomyces cerevisiae. |
Q44530427 | The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair |
Q34895336 | The effects of mismatch repair and RAD1 genes on interchromosomal crossover recombination in Saccharomyces cerevisiae |
Q34526958 | The genetics of the target tissue in rheumatoid arthritis |
Q28258968 | The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch |
Q24596494 | The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2 |
Q28137782 | The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer |
Q33984289 | The many faces of mismatch repair in meiosis |
Q41064501 | The mismatch repair system contributes to meiotic sterility in an interspecific yeast hybrid. |
Q40020196 | The mismatch repair system reduces meiotic homeologous recombination and stimulates recombination-dependent chromosome loss |
Q36329441 | The role of Drosophila mismatch repair in suppressing recombination between diverged sequences |
Q33592366 | The role of mismatch repair in the prevention of base pair mutations in Saccharomyces cerevisiae |
Q71616387 | Transcription of mutS and mutL-homologous genes in Saccharomyces cerevisiae during the cell cycle |
Q50724526 | Trapping and visualizing intermediate steps in the mismatch repair pathway in vivo. |
Q73318790 | Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency |
Q28508905 | Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair |
Q24674130 | Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly |
Q36338245 | Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. |
Q27935389 | exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair |
Q38362634 | hMSH2-independent DNA mismatch recognition by human proteins |
Q24292227 | hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA. |
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