DNA mismatch repair and cancer

scientific article published on 01 June 1998

DNA mismatch repair and cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0955-0674(98)80005-7
P698PubMed publication ID9640530

P2093author name stringT A Prolla
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Mutations of two PMS homologues in hereditary nonpolyposis colon cancerQ24318484
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repairQ24318892
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instabilityQ24319995
The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairsQ27930815
Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition.Q27932001
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancerQ28257360
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing overQ28282791
Escherichia coli mutS-encoded protein binds to mismatched DNA base pairsQ28287503
Mutations of GTBP in genetically unstable cellsQ28292802
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancerQ28294774
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repairQ28508905
Meiotic pachytene arrest in MLH1-deficient miceQ28510650
Mutation in the mismatch repair gene Msh6 causes cancer susceptibilityQ28592583
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repairQ29615027
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repairQ29618879
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiaeQ33842093
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologsQ34554581
Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins.Q34625095
Repair tracts in mismatched DNA heteroduplexesQ35037122
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunitQ35598571
Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB.Q36182527
Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutationsQ36570003
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coliQ36856385
APC mutations in colorectal tumors with mismatch repair deficiencyQ37383704
Mechanisms of DNA-mismatch correctionQ37858946
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosisQ38293261
The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertionsQ38299752
Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12Q39938870
High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12.Q40388905
Molecular matchmakersQ40885529
Microsatellite instability and DNA mismatch repair in human cancerQ41025066
hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agentsQ41100219
Hypermutability and mismatch repair deficiency in RER+ tumor cellsQ41508298
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Clues to the pathogenesis of familial colorectal cancerQ42622043
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.Q53445992
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.Q55066538
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patientsQ57570041
Mismatch correction at O 6 -methylguanine residues in E. coli DNAQ59049241
The E. coli uvrD gene product is DNA helicase IIQ60205950
N-Methyl-N'-nitro-N-nitrosoguanidine sensitivity of E. coli mutants deficient in DNA methylation and mismatch repairQ70221033
Molecular analysis of mutations in mutator colorectal carcinoma cell linesQ70972736
An adaptive response to the cytotoxic effects of N-methyl-N-nitrosourea is apparently absent in normal human fibroblastsQ71627385
P433issue3
P921main subjectDNA mismatch repairQ2984243
P304page(s)311-316
P577publication date1998-06-01
P1433published inCurrent Opinion in Cell BiologyQ13505682
P1476titleDNA mismatch repair and cancer
P478volume10

Reverse relations

cites work (P2860)
Q83398654A convenient fluorescent-labeled assay for in vitro measurement of DNA mismatch repair activity
Q44177099Association between Mismatch-repair Genetic variation and the Risk of Multiple Primary Cancers: A Meta-Analysis
Q34503454Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
Q36643467Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients
Q34568596DNA mismatch repair defects: role in colorectal carcinogenesis
Q33537493DNA secondary structure: a common and causative factor for expansion in human disease
Q28592033Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells
Q48731412Gene expression profiling defines molecular subtypes of classical Hodgkin's disease
Q26810051Genetic and epigenetic interactions in allopolyploid plants
Q24553992Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
Q36828042Measurement of DNA mismatch repair activity in live cells
Q44280420Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer
Q83835402Microsatellite instability in colorectal cancer: from molecular oncogenic mechanisms to clinical implications
Q38314351Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad51l3.
Q33756019Mismatch repair and immunoglobulin gene hypermutation: did we learn something?
Q28363159Molecular predictors of survival after adjuvant chemotherapy for colon cancer
Q55060101Mutational signatures and mutable motifs in cancer genomes.
Q35063954Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.
Q34612512Requirement for Msh6, but not for Swi4 (Msh3), in Msh2-dependent repair of base-base mismatches and mononucleotide loops in Schizosaccharomyces pombe
Q33941481Suppression of gene amplification and chromosomal DNA integration by the DNA mismatch repair system
Q33984337The Saccharomyces repair genes at the end of the century
Q31497967The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders
Q34804028The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors
Q24621737Unbalanced replication as a major source of genetic instability in cancer cells
Q83139208hMLH1 and MGMT inactivation as a mechanism of tumorigenesis in monoclonal gammopathies

Search more.