scholarly article | Q13442814 |
P2093 | author name string | J. W. Pollard | |
R. Kucherlapati | |||
N. Yu | |||
K. Lau | |||
W. Edelmann | |||
R. Kolodner | |||
M. Lipkin | |||
K. Fan | |||
K. Yang | |||
A. Umar | |||
J. Heyer | |||
T. Kunkel | |||
G. F. Crouse | |||
J. R. Lipford | |||
M. F. Kane | |||
P. E. Cohen | |||
W. Liedtke | |||
P2860 | cites work | Mutations of two PMS homologues in hereditary nonpolyposis colon cancer | Q24318484 |
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair | Q24318892 | ||
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients | Q57570041 | ||
Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer | Q58862199 | ||
Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability | Q71081409 | ||
Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients | Q72608543 | ||
A genetic map of the mouse with 4,006 simple sequence length polymorphisms | Q72702943 | ||
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6 | Q24323176 | ||
Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3. | Q27934985 | ||
Mutation of a mutL homolog in hereditary colon cancer | Q28114939 | ||
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer | Q28256988 | ||
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer | Q28257360 | ||
Biochemistry and genetics of eukaryotic mismatch repair | Q28282377 | ||
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over | Q28282791 | ||
Identification of mismatch repair genes and their role in the development of cancer | Q28288647 | ||
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells | Q28292781 | ||
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells | Q28292790 | ||
Mutations of GTBP in genetically unstable cells | Q28292802 | ||
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer | Q28294774 | ||
Polymerase delta variants in RER colorectal tumours | Q28299236 | ||
Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations | Q28299699 | ||
MSH2 deficient mice are viable and susceptible to lymphoid tumours | Q28508486 | ||
Meiotic pachytene arrest in MLH1-deficient mice | Q28510650 | ||
hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA | Q28610839 | ||
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes | Q29547355 | ||
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair | Q29615027 | ||
Mismatch repair in replication fidelity, genetic recombination, and cancer biology | Q29616483 | ||
WW6: an embryonic stem cell line with an inert genetic marker that can be traced in chimeras | Q34049134 | ||
Mice develop normally without the H1(0) linker histone | Q34126573 | ||
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs | Q34554581 | ||
Mutator phenotypes in human colorectal carcinoma cell lines | Q35568305 | ||
Mechanisms and biological effects of mismatch repair | Q37041860 | ||
APC mutations in colorectal tumors with mismatch repair deficiency | Q37383704 | ||
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis | Q38293261 | ||
Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype | Q38358374 | ||
Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes | Q40022200 | ||
Mismatch repair and cancer susceptibility | Q40535755 | ||
A hPMS2 mutant cell line is defective in strand-specific mismatch repair | Q41313494 | ||
Mismatch Repair Deficiency in Phenotypically Normal Human Cells | Q41347026 | ||
DNA loop repair by human cell extracts | Q41429743 | ||
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast | Q42427955 | ||
Clues to the pathogenesis of familial colorectal cancer | Q42622043 | ||
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation | Q46049171 | ||
cDNA sequence, map, and expression of the murine homolog of GTBP, a DNA mismatch repair gene. | Q48060657 | ||
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer | Q48084125 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA mismatch repair | Q2984243 |
MutS homolog 6 | Q14911719 | ||
P304 | page(s) | 467–477 | |
P577 | publication date | 1997-11-14 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Mutation in the mismatch repair gene Msh6 causes cancer susceptibility | |
P478 | volume | 91 |
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