scholarly article | Q13442814 |
P2093 | author name string | Aaron R Ellison | |
Grant A Bitter | |||
Joan Lofing | |||
P2860 | cites work | The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage | Q22010200 |
MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability | Q22010995 | ||
Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae | Q24291685 | ||
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2 | Q24314329 | ||
The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair | Q24321288 | ||
Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindreds | Q24535557 | ||
Transformation of intact yeast cells treated with alkali cations | Q24672708 | ||
N-terminus of hMLH1 confers interaction of hMutLalpha and hMutLbeta with hMutSalpha | Q24679608 | ||
Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair | Q27617873 | ||
Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis | Q27766073 | ||
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae | Q27860636 | ||
Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha. | Q27929951 | ||
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations | Q27935158 | ||
exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair | Q27935389 | ||
Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins | Q27937399 | ||
Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous-tail removal during recombination | Q27938377 | ||
Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair | Q27938608 | ||
Eukaryotic DNA mismatch repair | Q27939116 | ||
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction | Q27939611 | ||
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis | Q27939891 | ||
Mutation of a mutL homolog in hereditary colon cancer | Q28114939 | ||
A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli | Q28131613 | ||
Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression | Q28131772 | ||
The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer | Q28137782 | ||
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex | Q28142999 | ||
Mutations predisposing to hereditary nonpolyposis colorectal cancer | Q28235642 | ||
The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch | Q28258968 | ||
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer | Q28294774 | ||
MSH2 deficient mice are viable and susceptible to lymphoid tumours | Q28508486 | ||
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair | Q28508905 | ||
Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes | Q28585862 | ||
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility | Q28592583 | ||
The role of mismatched nucleotides in activating the hMSH2-hMSH6 molecular switch | Q28610649 | ||
Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A | Q28610670 | ||
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair | Q29615027 | ||
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair | Q29618879 | ||
The distribution of the numbers of mutants in bacterial populations | Q29620123 | ||
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. | Q30454407 | ||
A yeast two-hybrid assay provides a simple way to evaluate the vast majority of hMLH1 germ-line mutations. | Q31146866 | ||
Genetic susceptibility to non-polyposis colorectal cancer | Q33764029 | ||
Mismatch repair defects in cancer | Q33885063 | ||
Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae | Q33933718 | ||
Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations. | Q33957827 | ||
Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis | Q33960642 | ||
Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast | Q34012877 | ||
DNA mismatch repair and genetic instability | Q34090778 | ||
Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha | Q34123282 | ||
Deficient DNA mismatch repair: a common etiologic factor for colon cancer | Q34189020 | ||
Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair | Q34463536 | ||
Analysis of conditional mutations in the Saccharomyces cerevisiae MLH1 gene in mismatch repair and in meiotic crossing over. | Q34614513 | ||
Functional analysis of human MutSalpha and MutSbeta complexes in yeast | Q34693488 | ||
Mismatch repair genes hMLH1 and hMSH2 and colorectal cancer: a HuGE review | Q34990750 | ||
Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae | Q36557503 | ||
Saccharomyces cerevisiae pms2 mutations are alleles of MLH1, and pms2-2 corresponds to a hereditary nonpolyposis colorectal carcinoma-causing missense mutation | Q36560284 | ||
Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations | Q36570003 | ||
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene | Q36643609 | ||
Mutator phenotype may be required for multistage carcinogenesis | Q37732904 | ||
Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosis | Q38344945 | ||
Dominant negative mutator mutations in the mutL gene of Escherichia coli | Q39716760 | ||
Mammalian p53 can function as a transcription factor in yeast | Q40421511 | ||
Mismatch repair, genetic stability, and cancer | Q40556409 | ||
Reporter gene regulation in Saccharomyces cerevisiae by the human p53 tumor suppressor protein | Q40689935 | ||
Contribution of human mlh1 and pms2 ATPase activities to DNA mismatch repair | Q40744193 | ||
Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation. | Q42676262 | ||
Germline MSH2 and MLH1 mutational spectrum in HNPCC families from Poland and the Baltic States | Q43075069 | ||
Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing. | Q46001047 | ||
Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae | Q47713981 | ||
Functional genetic tests of DNA mismatch repair protein activity in Saccharomyces cerevisiae | Q47962525 | ||
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer | Q48084125 | ||
Defects in mismatch repair promote telomerase-independent proliferation | Q48361396 | ||
Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds. | Q50627228 | ||
Function of hybrid human-yeast cyclin-dependent kinases in Saccharomyces cerevisiae. | Q52532719 | ||
Mutator phenotypes of common polymorphisms and missense mutations in MSH2. | Q54360036 | ||
Interpretation of Genetic Test Results for Hereditary Nonpolyposis Colorectal Cancer | Q57591274 | ||
Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families | Q58862127 | ||
Screening patients for heterozygous p53 mutations using a functional assay in yeast | Q72635302 | ||
Inhibition of nonsense-mediated messenger RNA decay in clinical samples facilitates detection of human MSH2 mutations with an in vivo fusion protein assay and conventional techniques | Q73555188 | ||
A human compound heterozygote for two MLH1 missense mutations | Q73777232 | ||
P433 | issue | 18 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA mismatch repair | Q2984243 |
P304 | page(s) | 5321-5338 | |
P577 | publication date | 2004-10-08 | |
P1433 | published in | Nucleic Acids Research | Q135122 |
P1476 | title | Human MutL homolog (MLH1) function in DNA mismatch repair: a prospective screen for missense mutations in the ATPase domain | |
P478 | volume | 32 |
Q34584251 | A novel c. 204 Ile68Met germline variant in exon 2 of the mutL homolog 1 gene in a colorectal cancer patient. |
Q47449157 | Comprehensive functional assessment of MLH1 variants of unknown significance |
Q45718448 | Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors. |
Q39581441 | Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays |
Q36670109 | Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis |
Q35869772 | Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics |
Q36190208 | Interaction between polymorphisms of DNA repair genes significantly modulated bladder cancer risk |
Q26774627 | Mouse models for the discovery of colorectal cancer driver genes |
Q33817381 | MutLα heterodimers modify the molecular phenotype of Friedreich ataxia |
Q36296744 | Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links |
Q34167290 | Single nucleotide polymorphisms of DNA mismatch repair genes MSH2 and MLH1 confer susceptibility to esophageal cancer |
Q57177032 | Using Somatic Mutations from Tumors to Classify Variants in Mismatch Repair Genes |
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