Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae

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Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae is …
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scholarly articleQ13442814

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P819ADS bibcode1995PNAS...9210418S
P356DOI10.1073/PNAS.92.22.10418
P932PMC publication ID40808
P698PubMed publication ID7479796
P5875ResearchGate publication ID15718897

P2093author name stringT D Petes
M Strand
G F Crouse
M C Earley
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Mutations of two PMS homologues in hereditary nonpolyposis colon cancerQ24318484
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instabilityQ24319995
Mutations of Bacteria from Virus Sensitivity to Virus ResistanceQ24533278
Identification of two initiator elements in the bidirectional promoter of the human dihydrofolate reductase and mismatch repair protein 1 genesQ24609037
Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functionsQ27932283
The yeast gene MSH3 defines a new class of eukaryotic MutS homologues.Q27937756
Mutation of a mutL homolog in hereditary colon cancerQ28114939
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistanceQ28131606
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancerQ28257360
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor CellsQ28292781
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repairQ29618879
Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteinsQ33960283
Marker effects of G to C transversions on intragenic recombination and mismatch repair in Schizosaccharomyces pombeQ33960709
Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiaeQ33964716
Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthdayQ34229913
Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB.Q36182527
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 geneQ36769994
Mechanisms and biological effects of mismatch repairQ37041860
Instability of simple sequence DNA in Saccharomyces cerevisiaeQ40655124
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instabilityQ41467421
Instability of simple sequence repeats in a mammalian cell lineQ41491923
Hypermutability and mismatch repair deficiency in RER+ tumor cellsQ41508298
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Clues to the pathogenesis of familial colorectal cancerQ42622043
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instabilityQ72127255
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
P304page(s)10418-10421
P577publication date1995-10-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae
P478volume92

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cites work (P2860)
Q36744978A Whole Genome Screen for Minisatellite Stability Genes in Stationary-Phase Yeast Cells
Q83339427A method to select for mutator DNA polymerase deltas in Saccharomyces cerevisiae
Q27934451A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition
Q34606404A mutation of the yeast gene encoding PCNA destabilizes both microsatellite and minisatellite DNA sequences
Q41031881A novel plasmid shuttle vector for the detection and analysis of microsatellite instability in cell lines
Q35878792Abundant microsatellite polymorphism in Saccharomyces cerevisiae, and the different distributions of microsatellites in eight prokaryotes and S. cerevisiae, result from strong mutation pressures and a variety of selective forces
Q34235281Analysis of microsatellite polymorphism in inbred knockout mice
Q34443496Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae
Q27934985Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3.
Q53244063Cadmium-induced microsatellite instability in the kidneys and leukocytes of C57BL/6J mice.
Q33952942Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms
Q57451645Correction of large mispaired DNA loops by extracts of Saccharomyces cerevisiae
Q28610848DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair
Q74701340DNA mismatch repair and cancer
Q41561505DNA mismatch repair gene mutations in human cancer
Q41536289DNA mismatch repair in mammals: role in disease and meiosis
Q41264767DNA repair and colorectal cancer
Q28709604DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae
Q91800201Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism
Q33967667Destabilization of simple repetitive DNA sequences by transcription in yeast.
Q33786528Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).
Q35034387Different roles of eukaryotic MutS and MutL complexes in repair of small insertion and deletion loops in yeast.
Q27932428Enhancement of MSH2-MSH3-mediated mismatch recognition by the yeast MLH1-PMS1 complex
Q33711830Eukaryotic Mismatch Repair in Relation to DNA Replication
Q27938608Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair
Q36553485Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α
Q36568343Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins
Q33791245Frameshift mutation, microsatellites and mismatch repair
Q55018082Frameshift mutations and a length polymorphism in the hMSH3 gene and the spectrum of microsatellite instability in sporadic colon cancer.
Q57978058Frameshift mutator mutations
Q48540606Functional assessment for elimination of mismatches in nuclear and whole cell extracts obtained from mouse and human blastocysts
Q47962525Functional genetic tests of DNA mismatch repair protein activity in Saccharomyces cerevisiae
Q34603929Functional overlap in mismatch repair by human MSH3 and MSH6.
Q41355776Genetic control of microsatellite stability
Q34359818Haplotype studies support slippage as the mechanism of germline mutations in short tandem repeats
Q33967684Homologous and homeologous intermolecular gene conversion are not differentially affected by mutations in the DNA damage or the mismatch repair genes RAD1, RAD50, RAD51, RAD52, RAD54, PMS1 and MSH2
Q36568353Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.
Q28364152Identification of a mutant DNA polymerase delta in Saccharomyces cerevisiae with an antimutator phenotype for frameshift mutations
Q39455847Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta
Q40022432Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae
Q47135454Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae.
Q34012877Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast
Q28610863Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha
Q48065235MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2.
Q27320576Mathematical and live meningococcal models for simple sequence repeat dynamics - coherent predictions and observations
Q42044589Mechanisms of dinucleotide repeat instability in Escherichia coli
Q34142398Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae
Q33970339Microsatellite Instability in Yeast: Dependence on the Length of the Microsatellite
Q24627393Microsatellite instability in colorectal cancer
Q40022200Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes
Q26771472Microsatellites in Pursuit of Microbial Genome Evolution
Q34057384Microsatellites: consensus and controversy
Q28262642Microsatellites: simple sequences with complex evolution
Q24681589Mismatch repair deficiency associated with overexpression of the MSH3 gene
Q33967893Mismatch repair mutants in yeast are not defective in transcription-coupled DNA repair of UV-induced DNA damage.
Q33984294Mismatch repair proteins and mitotic genome stability
Q36557503Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae
Q28303186MutS homologs in mammalian cells
Q24318892Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
Q28235642Mutations predisposing to hereditary nonpolyposis colorectal cancer
Q34097342Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication
Q36090192Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands
Q34975960Pathogenesis and clinical management of hereditary non-polyposis colorectal cancer
Q36733353Physical interaction between components of DNA mismatch repair and nucleotide excision repair
Q41886077Recognition of DNA alterations by the mismatch repair system
Q28254808Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC1
Q33865368Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae
Q42660015Replication errors: cha(lle)nging the genome
Q41099585Saccharomyces cerevisiae DNA repair processes: an update
Q27932017Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair
Q42967686Stabilization of microsatellite sequences by variant repeats in the yeast Saccharomyces cerevisiae
Q33957467The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae
Q28551589The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis
Q27935158The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations
Q27930815The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs
Q41477080The complex pathology of trinucleotide repeats
Q24814928The immunogenicity of colorectal cancers with high-degree microsatellite instability
Q33968093The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions.
Q36571784The rate and spectrum of microsatellite mutation in Caenorhabditis elegans and Daphnia pulex
Q71806485The stabilization of repetitive tracts of DNA by variant repeats requires a functional DNA mismatch repair system
Q41879541The yeast HSM3 gene acts in one of the mismatch repair pathways.
Q93216537Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts
Q39847637Two distinct models account for short and long deletions within sequence repeats in Escherichia coli
Q47148057Whole Genome Sequence Analysis of Mutations Accumulated in rad27Δ Yeast Strains with Defects in the Processing of Okazaki Fragments Indicates Template-Switching Events
Q24323176hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
Q28610839hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

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