DNA mismatch repair gene mutations in human cancer

scientific article published on June 1997

DNA mismatch repair gene mutations in human cancer is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1289/EHP.97105S4775
P932PMC publication ID1470030
P698PubMed publication ID9255561
P5875ResearchGate publication ID13963746

P2093author name stringPeltomäki P
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Mutations of two PMS homologues in hereditary nonpolyposis colon cancerQ24318484
ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3Q24321908
Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresisQ24671692
Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genesQ28119040
Binding of mismatched microsatellite DNA sequences by the human MSH2 proteinQ28241673
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancerQ28257360
Genetic mapping of a locus predisposing to human colorectal cancerQ28268634
Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase geneQ28275920
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing overQ28282791
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor CellsQ28292781
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cellsQ28292790
Mutations of GTBP in genetically unstable cellsQ28292802
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancerQ28294774
MSH2 deficient mice are viable and susceptible to lymphoid tumoursQ28508486
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repairQ29618879
Microsatellite instability in cancer of the proximal colonQ29620692
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiaeQ33842093
Genomic organization of the human PMS2 gene family.Q34373629
A simple p53 functional assay for screening cell lines, blood, and tumorsQ34397902
Cloning and expression of the Xenopus and mouse Msh2 DNA mismatch repair genes.Q35004871
Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reactionQ35247229
Mutator phenotypes in human colorectal carcinoma cell linesQ35568305
Microsatellite alterations as clonal markers for the detection of human cancerQ35819311
How many mutations are required for tumorigenesis? Implications from human cancer dataQ36782475
Mechanisms and biological effects of mismatch repairQ37041860
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosisQ38293261
High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12.Q40388905
Mechanisms of DNA excision repairQ40556396
Mismatch repair, genetic stability, and cancerQ40556409
Microsatellite instability: marker of a mutator phenotype in cancer.Q40630726
Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated reviewQ40901949
Genetics of hereditary colon cancerQ41126304
Monoallelic mutation analysis (MAMA) for identifying germline mutationsQ41306100
Mismatch Repair Deficiency in Phenotypically Normal Human CellsQ41347026
DNA loop repair by human cell extractsQ41429743
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instabilityQ41467421
Hypermutability and mismatch repair deficiency in RER+ tumor cellsQ41508298
Genetic consequences of tolerance to methylation DNA damage in mammalian cellsQ41524494
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Clues to the pathogenesis of familial colorectal cancerQ42622043
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformationQ46049171
Microsatellite instability in sporadic endometrial carcinomaQ46250416
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
Instability of short tandem repeats (microsatellites) in human cancers.Q48181678
Microsatellite instability in colorectal cancer: improved assessment using fluorescent polymerase chain reaction.Q52870388
Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile.Q53465959
Genomic instability of microsatellite repeats and its association with the evolution of chronic myelogenous leukemia.Q53471593
Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.Q53477421
DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancerQ57200636
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancerQ57568035
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patientsQ57570041
A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instabilityQ59156997
Heteroduplex repair in extracts of human HeLa cellsQ68198738
In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancerQ71737275
Mismatch repair, somatic mutations, and the origins of cancerQ71805147
Microsatellite instability occurs frequently and in both diploid and aneuploid cell populations of Barrett's-associated esophageal adenocarcinomasQ72018711
A hereditary genetic marker closely associated with microsatellite instability in lung cancerQ72033731
Genomic instability of microsatellite repeats and mutations of H-, K-, and N-ras, and p53 genes in renal cell carcinomaQ72065156
Replication error-type genetic instability at 1q42-43 in human male germ cell tumorsQ72065274
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instabilityQ72127255
High frequency of mutator phenotype in human prostatic adenocarcinomaQ72185095
Microsatellite instability and loss of heterozygosity in breast cancerQ72313887
Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patientsQ72313890
Microsatellite instability and other molecular abnormalities in non-small cell lung cancerQ72368568
Genetic instability of microsatellite sequences in many non-small cell lung carcinomasQ72399771
Frequent microsatellite instability in primary small cell lung cancerQ72399781
Chromosome 9 allelic losses and microsatellite alterations in human bladder tumorsQ72428452
Genetic instability of microsatellites in endometrial carcinomaQ72559451
Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patientsQ72608543
Microsatellite instability in bladder cancerQ72613246
Genomic instability in colorectal cancer: relationship to clinicopathological variables and family historyQ72657539
Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndromeQ72657543
Microsatellite instability occurs frequently in human gastric carcinomaQ72760038
Instability of microsatellites in rat colon tumors induced by heterocyclic aminesQ72875184
P921main subjectDNA repairQ210538
genetic variationQ349856
mutationQ42918
Lynch syndromeQ783644
DNA mismatch repairQ2984243
P304page(s)775-780
P577publication date1997-06-01
P1433published inEnvironmental Health PerspectivesQ1345904
P1476titleDNA mismatch repair gene mutations in human cancer
P478volume105 Suppl 4

Reverse relations

cites work (P2860)
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Q74462661A comparative analysis of allelic imbalance events in chemically induced rat mammary, colon, and bladder tumors
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Q37169725Genetic changes of p53, K-ras, and microsatellite instability in gallbladder carcinoma in high-incidence areas of Japan and Hungary
Q33764029Genetic susceptibility to non-polyposis colorectal cancer
Q36622540Immunohistochemical analysis of expression and allelotype of mismatch repair genes (hMLH1 and hMSH2) in bladder cancer
Q47630690Lynch syndrome and sextuple primary malignancies.
Q35548710Mismatch repair and response to DNA-damaging antitumour therapies
Q84301243Missense mutations in MLH1, MSH2, KRAS, and APC genes in colorectal cancer patients in Malaysia
Q64389865Regulation of DNA repair by non-coding miRNAs
Q35827560Rheumatoid Arthritis as a Therapeutic Challenge in a Patient with Lynch Syndrome
Q33984337The Saccharomyces repair genes at the end of the century
Q45296256The influence of DNA glycosylases on spontaneous mutation

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