scholarly article | Q13442814 |
P50 | author | Nadine Kolas | Q30303526 |
P2093 | author name string | Thomas A Kunkel | |
Richard D Kolodner | |||
Tchaiko Parris | |||
Winfried Edelmann | |||
Edmund Wong | |||
Michael F Kane | |||
Alan B Clark | |||
Robert Russell | |||
Paula E Cohen | |||
Burkhard Kneitz | |||
Harry Hou | |||
Dan J Mazur | |||
Kaichun Wei | |||
Guohze Yang | |||
P2860 | cites work | Human exonuclease I interacts with the mismatch repair protein hMSH2 | Q22004013 |
The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities | Q22010967 | ||
The interaction of DNA mismatch repair proteins with human exonuclease I | Q24291370 | ||
Human exonuclease I is required for 5' and 3' mismatch repair | Q24292224 | ||
Molecular interactions of human Exo1 with DNA | Q24292290 | ||
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2 | Q24314329 | ||
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice | Q24606421 | ||
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations | Q27935158 | ||
exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair | Q27935389 | ||
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction | Q27939611 | ||
Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae | Q28140402 | ||
Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms | Q28190757 | ||
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer | Q28202143 | ||
Biochemistry and genetics of eukaryotic mismatch repair | Q28282377 | ||
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over | Q28282791 | ||
Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination | Q28289308 | ||
Mammalian MutS homologue 5 is required for chromosome pairing in meiosis | Q28295022 | ||
Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity | Q28507875 | ||
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair | Q28508905 | ||
Meiotic pachytene arrest in MLH1-deficient mice | Q28510650 | ||
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression | Q28513250 | ||
Expression specificity of the mouse exonuclease 1 (mExo1) gene | Q28585040 | ||
Mouse models for hereditary nonpolyposis colorectal cancer | Q28585761 | ||
Meiotic prophase abnormalities and metaphase cell death in MLH1-deficient mouse spermatocytes: insights into regulation of spermatogenic progress | Q28586542 | ||
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice | Q28589732 | ||
Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice | Q28593189 | ||
Meiotic arrest and aneuploidy in MLH3-deficient mice | Q28593875 | ||
Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha | Q28610863 | ||
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair | Q29615027 | ||
Mismatch repair in replication fidelity, genetic recombination, and cancer biology | Q29616483 | ||
Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog | Q29618405 | ||
Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae | Q33933718 | ||
The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae | Q33957467 | ||
Genetic analysis of mouse embryonic stem cells bearing Msh3 and Msh2 single and compound mutations | Q33961252 | ||
Destabilization of simple repetitive DNA sequences by transcription in yeast. | Q33967667 | ||
Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation | Q34157868 | ||
Deficient DNA mismatch repair: a common etiologic factor for colon cancer | Q34189020 | ||
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs | Q34554581 | ||
Functional overlap in mismatch repair by human MSH3 and MSH6. | Q34603929 | ||
EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae | Q34609730 | ||
A DNA polymerase epsilon mutant that specifically causes +1 frameshift mutations within homonucleotide runs in yeast | Q34610131 | ||
Decreased meiotic intergenic recombination and increased meiosis I nondisjunction in exo1 mutants of Saccharomyces cerevisiae | Q34611088 | ||
Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). | Q34614221 | ||
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair | Q36235057 | ||
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro | Q36568265 | ||
Mechanisms and biological effects of mismatch repair | Q37041860 | ||
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis | Q38293261 | ||
Bidirectional excision in methyl-directed mismatch repair | Q38318540 | ||
Methyl-directed mismatch repair is bidirectional | Q38318556 | ||
Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex | Q38337751 | ||
MutS and MutL activate DNA helicase II in a mismatch-dependent manner | Q38337755 | ||
Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair | Q39724404 | ||
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants | Q39860143 | ||
The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair | Q41396267 | ||
A 5'-3' exonuclease from Saccharomyces cerevisiae is required for in vitro recombination between linear DNA molecules with overlapping homology | Q42151362 | ||
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast | Q42427955 | ||
The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis | Q47858327 | ||
A DNA exonuclease induced during meiosis of Schizosaccharomyces pombe. | Q53926783 | ||
A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction. | Q53963518 | ||
Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer | Q61946741 | ||
EXO1 and MSH4 differentially affect crossing-over and segregation | Q73899517 | ||
Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair | Q74064844 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA mismatch repair | Q2984243 |
P304 | page(s) | 603-14 | |
P577 | publication date | 2003-03-01 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility | |
P478 | volume | 17 |
Q35583181 | 14-3-3 proteins restrain the Exo1 nuclease to prevent overresection. |
Q51769143 | A Reassessment of Genes Modulating Aging in Mice Using Demographic Measurements of the Rate of Aging. |
Q24298110 | A defined human system that supports bidirectional mismatch-provoked excision |
Q36749550 | A mutation in EXO1 defines separable roles in DNA mismatch repair and post-replication repair. |
Q36540457 | A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair |
Q37181822 | A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair |
Q36457060 | ATR-dependent pathways control hEXO1 stability in response to stalled forks. |
Q35690218 | Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System |
Q36954874 | Activities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regions |
Q50671986 | Age-associated alteration of gene expression patterns in mouse oocytes. |
Q28513971 | Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice |
Q33822488 | An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents |
Q47445150 | Analysis of factors decreasing testis weight in MRL mice |
Q33247666 | Analysis of the excision step in human DNA mismatch repair |
Q37699397 | Associations between single-nucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma |
Q33791321 | Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1. |
Q33604620 | Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates |
Q46726051 | Bound nucleotide controls the endonuclease activity of mismatch repair enzyme MutL. |
Q28534478 | Breast tumors with elevated expression of 1q candidate genes confer poor clinical outcome and sensitivity to Ras/PI3K inhibition |
Q28115810 | CSB-PGBD3 Mutations Cause Premature Ovarian Failure |
Q45129820 | Cadmium inhibits the functions of eukaryotic MutS complexes. |
Q27026386 | Causal link between microsatellite instability and hMRE11 dysfunction in human cancers |
Q85228405 | Characterization of C- and N-terminal domains of Aquifex aeolicus MutL endonuclease: N-terminal domain stimulates the endonuclease activity of C-terminal domain in a zinc-dependent manner |
Q37072156 | Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair |
Q34411080 | Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae |
Q57784307 | Coordinating Multi-Protein Mismatch Repair by Managing Diffusion Mechanics on the DNA |
Q33703015 | CtIP-mediated resection is essential for viability and can operate independently of BRCA1. |
Q36884849 | DNA Mismatch Repair Interacts with CAF-1- and ASF1A-H3-H4-dependent Histone (H3-H4)2 Tetramer Deposition |
Q38036830 | DNA damage checkpoints in stem cells, ageing and cancer. |
Q34814254 | DNA mismatch repair and infertility |
Q28291067 | DNA mismatch repair in eukaryotes and bacteria |
Q24647002 | DNA mismatch repair: molecular mechanism, cancer, and ageing |
Q52605096 | DNA repair and cell cycle checkpoint defects in a mouse model of 'BRCAness' are partially rescued by 53BP1 deletion. |
Q35020482 | DNA repair gene polymorphisms and tobacco smoking in the risk for colorectal adenomas |
Q36487307 | DNA-damage repair; the good, the bad, and the ugly |
Q52720061 | Deoxyribonucleic Acid Damage and Repair: Capitalizing on Our Understanding of the Mechanisms of Maintaining Genomic Integrity for Therapeutic Purposes. |
Q51039462 | Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors. |
Q50666210 | Developmental regulation and in vitro culture effects on expression of DNA repair and cell cycle checkpoint control genes in rhesus monkey oocytes and embryos. |
Q44761854 | Differential requirement for proliferating cell nuclear antigen in 5' and 3' nick-directed excision in human mismatch repair |
Q33529100 | Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA |
Q36670109 | Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis |
Q47070570 | DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork |
Q28534756 | Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway |
Q97073533 | EXO1 Plays a Carcinogenic Role in Hepatocellular Carcinoma and is related to the regulation of FOXP3 |
Q36002464 | EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele |
Q48587042 | EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells |
Q37964747 | Emerging evidence for the role of genomic instability in male factor infertility |
Q36764079 | Endonuclease activities of MutLα and its homologs in DNA mismatch repair |
Q33711830 | Eukaryotic Mismatch Repair in Relation to DNA Replication |
Q28551519 | Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites |
Q36115776 | Evidence that the DNA mismatch repair system removes 1-nucleotide Okazaki fragment flaps |
Q38974172 | Exo1 independent DNA mismatch repair involves multiple compensatory nucleases |
Q35564759 | Exo1 phosphorylation status controls the hydroxyurea sensitivity of cells lacking the Pol32 subunit of DNA polymerases delta and zeta |
Q36421123 | Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents |
Q38919536 | Exonuclease 1 and its versatile roles in DNA repair |
Q33573646 | Exonuclease 1 is a critical mediator of survival during DNA double strand break repair in nonquiescent hematopoietic stem and progenitor cells |
Q28261787 | Exonuclease 1-dependent and independent mismatch repair |
Q33297433 | Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice |
Q42043478 | Fen-1 facilitates homologous recombination by removing divergent sequences at DNA break ends |
Q35663520 | Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis |
Q36046488 | Genetic risk of lung cancer associated with a single nucleotide polymorphism from EXO1: a meta analysis. |
Q33631793 | Genome-wide identification of CBX2 targets: insights in the human sex development network |
Q47766916 | Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro |
Q35170755 | Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation |
Q33224078 | Human mismatch repair: reconstitution of a nick-directed bidirectional reaction |
Q33791326 | Hydrolytic function of Exo1 in mammalian mismatch repair. |
Q90647988 | Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners |
Q64376748 | Identification of a panel of MYC and Tip60 co-regulated genes functioning primarily in cell cycle and DNA replication |
Q36741556 | Identification of regulatory factor X as a novel mismatch repair stimulatory factor |
Q28074585 | Impact of DNA mismatch repair system alterations on human fertility and related treatments |
Q39991083 | Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine |
Q52769433 | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. |
Q47135454 | Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae. |
Q37215365 | Involvement of Exo1b in DNA damage-induced apoptosis |
Q35792957 | Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias |
Q33369076 | MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis |
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Q37590653 | Male infertility: a risk factor for testicular cancer |
Q35585478 | Male reproductive cancers and infertility: a mutual relationship |
Q35875365 | Male reproductive health and prostate cancer risk |
Q36991032 | Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes |
Q26740310 | Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer |
Q51793302 | Measuring strand discontinuity-directed mismatch repair in yeast Saccharomyces cerevisiae by cell-free nuclear extracts. |
Q24300483 | Mechanism of 5'-directed excision in human mismatch repair |
Q36547669 | Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching |
Q28262719 | Mechanisms and functions of DNA mismatch repair |
Q36564560 | Mechanisms in eukaryotic mismatch repair |
Q38618828 | Meiotic Recombination: The Essence of Heredity |
Q38153644 | Meiotic recombination in mammals: localization and regulation |
Q35910256 | Meiotic recombination intermediates and mismatch repair proteins |
Q34248904 | Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways |
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Q34773522 | Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining |
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Q28084645 | New insights into the mechanism of DNA mismatch repair |
Q35829272 | Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1) |
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Q37011985 | Nucleosome dynamics regulates DNA processing |
Q37037194 | O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo |
Q35893147 | Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex |
Q24632622 | Okazaki fragment maturation: nucleases take centre stage |
Q33961620 | PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. |
Q24606670 | PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair |
Q36258155 | PHF11 promotes DSB resection, ATR signaling, and HR. |
Q34068165 | PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance |
Q33519468 | Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks |
Q34488378 | Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. |
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Q36521428 | Structure and function of the components of the human DNA mismatch repair system |
Q27667527 | Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family |
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Q37334051 | The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs |
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